DE69523571D1 - Pyridylimidazol-derivate und verfahren zu ihrer herstellung - Google Patents

Pyridylimidazol-derivate und verfahren zu ihrer herstellung

Info

Publication number
DE69523571D1
DE69523571D1 DE69523571T DE69523571T DE69523571D1 DE 69523571 D1 DE69523571 D1 DE 69523571D1 DE 69523571 T DE69523571 T DE 69523571T DE 69523571 T DE69523571 T DE 69523571T DE 69523571 D1 DE69523571 D1 DE 69523571D1
Authority
DE
Germany
Prior art keywords
production
pyridylimidazole derivatives
pyridylimidazole
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69523571T
Other languages
English (en)
Other versions
DE69523571T2 (de
Inventor
Eun Yoo
Yang Yi
Hee Lee
Ryung Kim
Hee Suh
Jeong Kim
Ju Kim
Ja Cha
Ah Shin
Sup Shin
Hou Lee
Sook Jung
Ho Lee
Won Seo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Chemical Technology KRICT
Original Assignee
Korea Research Institute of Chemical Technology KRICT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute of Chemical Technology KRICT filed Critical Korea Research Institute of Chemical Technology KRICT
Publication of DE69523571D1 publication Critical patent/DE69523571D1/de
Application granted granted Critical
Publication of DE69523571T2 publication Critical patent/DE69523571T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE69523571T 1994-02-08 1995-02-08 Pyridylimidazol-derivate und verfahren zu ihrer herstellung Expired - Fee Related DE69523571T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
KR19940002354 1994-02-08
KR19940013795 1994-06-18
KR19940017900 1994-07-25
KR1019950001286A KR0151816B1 (ko) 1994-02-08 1995-01-25 신규의 치환된 피리딜 이미다졸 유도체 및 그의 제조방법
PCT/KR1995/000009 WO1995021838A1 (en) 1994-02-08 1995-02-08 Pyridyl imidazole derivatives and processes for the preparation thereof

Publications (2)

Publication Number Publication Date
DE69523571D1 true DE69523571D1 (de) 2001-12-06
DE69523571T2 DE69523571T2 (de) 2002-07-25

Family

ID=27483030

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69523571T Expired - Fee Related DE69523571T2 (de) 1994-02-08 1995-02-08 Pyridylimidazol-derivate und verfahren zu ihrer herstellung

Country Status (9)

Country Link
US (1) US5849753A (de)
EP (1) EP0743943B1 (de)
JP (1) JP2905599B2 (de)
KR (1) KR0151816B1 (de)
AU (1) AU691879B2 (de)
CA (1) CA2182477C (de)
DE (1) DE69523571T2 (de)
ES (1) ES2166816T3 (de)
WO (1) WO1995021838A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ502642A (en) * 1997-07-03 2002-06-28 Du Pont Pharm Co Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
US6465484B1 (en) * 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
AR051596A1 (es) * 2004-10-26 2007-01-24 Irm Llc Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios
ES2274712B1 (es) * 2005-10-06 2008-03-01 Laboratorios Almirall S.A. Nuevos derivados imidazopiridina.
KR101117128B1 (ko) * 2009-06-02 2012-03-14 한국화학연구원 페닐테트라졸 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 골다공증 또는 비만의 예방 또는 치료용 약학적 조성물
US8372862B2 (en) * 2009-06-02 2013-02-12 Korea Research Institute Of Chemical Technology Pharmaceutical composition for preventing or treating osteoporosis or obesity comprising phenyltetrazole derivative
WO2011134019A1 (en) * 2010-04-30 2011-11-03 The University Of Melbourne Novel biphenyl sartans
KR20140040801A (ko) * 2011-07-15 2014-04-03 시오노기세야쿠 가부시키가이샤 Ａｍｐｋ 활성화 작용을 갖는 아자벤즈이미다졸 유도체
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
IE70593B1 (en) * 1989-09-29 1996-12-11 Eisai Co Ltd Biphenylmethane derivative the use of it and pharmacological compositions containing same
IL96019A0 (en) * 1989-10-31 1991-07-18 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5053329A (en) * 1990-07-05 1991-10-01 Merck & Co., Inc. Process for preparation of novel angiotensin II antagonists
US5066586A (en) * 1990-08-20 1991-11-19 Merck & Co., Inc. Process for preparation of novel angiotensin II antagonists
US5049565A (en) * 1990-12-07 1991-09-17 Merck & Co., Inc. Microbial transformation process for preparing anti-hypertensive products

Also Published As

Publication number Publication date
KR950025039A (ko) 1995-09-15
CA2182477C (en) 1999-06-15
AU691879B2 (en) 1998-05-28
DE69523571T2 (de) 2002-07-25
EP0743943A1 (de) 1996-11-27
JP2905599B2 (ja) 1999-06-14
US5849753A (en) 1998-12-15
KR0151816B1 (ko) 1998-10-15
CA2182477A1 (en) 1995-08-17
WO1995021838A1 (en) 1995-08-17
JPH09507675A (ja) 1997-08-05
ES2166816T3 (es) 2002-05-01
AU1718495A (en) 1995-08-29
EP0743943B1 (de) 2001-10-31

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee