ES2166816T3 - Derivados piridil-imidazolicos y procedimientos para su preparacion. - Google Patents

Derivados piridil-imidazolicos y procedimientos para su preparacion.

Info

Publication number
ES2166816T3
ES2166816T3 ES95909125T ES95909125T ES2166816T3 ES 2166816 T3 ES2166816 T3 ES 2166816T3 ES 95909125 T ES95909125 T ES 95909125T ES 95909125 T ES95909125 T ES 95909125T ES 2166816 T3 ES2166816 T3 ES 2166816T3
Authority
ES
Spain
Prior art keywords
piridil
procedures
preparation
derivatives
imidazolic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES95909125T
Other languages
English (en)
Inventor
Sung Eun Yoo
Kyu Yang Yi
Sang Hee Lee
Hye Ryung Kim
Jee Hee Suh
Nak Jeong Kim
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Korea Research Institute of Chemical Technology KRICT
Original Assignee
Korea Research Institute of Chemical Technology KRICT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Korea Research Institute of Chemical Technology KRICT filed Critical Korea Research Institute of Chemical Technology KRICT
Application granted granted Critical
Publication of ES2166816T3 publication Critical patent/ES2166816T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/415—1,2-Diazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

NUEVOS DERIVADOS SUSTITUIDOS DE PIRIDIL IMIDAZOL DE FORMULA (I) INHIBEN EFICAZMENTE LA ACCION DE LA ANGIOTENSINA II Y TIENEN UNA ACTIVIDAD ANTIHIPERTENSORA SUPERIOR.
ES95909125T 1994-02-08 1995-02-08 Derivados piridil-imidazolicos y procedimientos para su preparacion. Expired - Lifetime ES2166816T3 (es)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
KR19940002354 1994-02-08
KR19940013795 1994-06-18
KR19940017900 1994-07-25
KR1019950001286A KR0151816B1 (ko) 1994-02-08 1995-01-25 신규의 치환된 피리딜 이미다졸 유도체 및 그의 제조방법

Publications (1)

Publication Number Publication Date
ES2166816T3 true ES2166816T3 (es) 2002-05-01

Family

ID=27483030

Family Applications (1)

Application Number Title Priority Date Filing Date
ES95909125T Expired - Lifetime ES2166816T3 (es) 1994-02-08 1995-02-08 Derivados piridil-imidazolicos y procedimientos para su preparacion.

Country Status (9)

Country Link
US (1) US5849753A (es)
EP (1) EP0743943B1 (es)
JP (1) JP2905599B2 (es)
KR (1) KR0151816B1 (es)
AU (1) AU691879B2 (es)
CA (1) CA2182477C (es)
DE (1) DE69523571T2 (es)
ES (1) ES2166816T3 (es)
WO (1) WO1995021838A1 (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HRP980375A2 (en) 1997-07-03 1999-04-30 Argyrios Georgios Arvanitis Imidazopyrimidines and imidazopyridines for the treatment of neurological disorders
US6465484B1 (en) * 1997-09-26 2002-10-15 Merck & Co., Inc. Angiogenesis inhibitors
US6365589B1 (en) 1998-07-02 2002-04-02 Bristol-Myers Squibb Pharma Company Imidazo-pyridines, -pyridazines, and -triazines as corticotropin releasing factor antagonists
AR051596A1 (es) * 2004-10-26 2007-01-24 Irm Llc Compuestos heterociclicos condensados nitrogenados como inhibidores de la actividad del receptor canabinoide 1; composiciones farmaceuticas que los contienen y su empleo en la preparacion de medicamentos para el tratamiento de trastornos alimentarios
ES2274712B1 (es) * 2005-10-06 2008-03-01 Laboratorios Almirall S.A. Nuevos derivados imidazopiridina.
KR101117128B1 (ko) * 2009-06-02 2012-03-14 한국화학연구원 페닐테트라졸 유도체 또는 이의 약학적으로 허용가능한 염을 유효성분으로 포함하는 골다공증 또는 비만의 예방 또는 치료용 약학적 조성물
US8372862B2 (en) 2009-06-02 2013-02-12 Korea Research Institute Of Chemical Technology Pharmaceutical composition for preventing or treating osteoporosis or obesity comprising phenyltetrazole derivative
WO2011134019A1 (en) * 2010-04-30 2011-11-03 The University Of Melbourne Novel biphenyl sartans
EP2733141B1 (en) * 2011-07-15 2019-01-09 Shionogi & Co., Ltd. Azabenzimidazole derivative having ampk-activating activity
WO2018002673A1 (en) 2016-07-01 2018-01-04 N4 Pharma Uk Limited Novel formulations of angiotensin ii receptor antagonists

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IE64514B1 (en) * 1989-05-23 1995-08-09 Zeneca Ltd Azaindenes
IL94390A (en) * 1989-05-30 1996-03-31 Merck & Co Inc The 6-membered trans-nitrogen-containing heterocycles are compressed with imidazo and pharmaceutical preparations containing them
IE70593B1 (en) * 1989-09-29 1996-12-11 Eisai Co Ltd Biphenylmethane derivative the use of it and pharmacological compositions containing same
IL96019A0 (en) * 1989-10-31 1991-07-18 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US5053329A (en) * 1990-07-05 1991-10-01 Merck & Co., Inc. Process for preparation of novel angiotensin II antagonists
US5066586A (en) * 1990-08-20 1991-11-19 Merck & Co., Inc. Process for preparation of novel angiotensin II antagonists
US5049565A (en) * 1990-12-07 1991-09-17 Merck & Co., Inc. Microbial transformation process for preparing anti-hypertensive products

Also Published As

Publication number Publication date
AU1718495A (en) 1995-08-29
KR0151816B1 (ko) 1998-10-15
AU691879B2 (en) 1998-05-28
JP2905599B2 (ja) 1999-06-14
KR950025039A (ko) 1995-09-15
DE69523571D1 (de) 2001-12-06
WO1995021838A1 (en) 1995-08-17
CA2182477A1 (en) 1995-08-17
EP0743943A1 (en) 1996-11-27
EP0743943B1 (en) 2001-10-31
DE69523571T2 (de) 2002-07-25
US5849753A (en) 1998-12-15
CA2182477C (en) 1999-06-15
JPH09507675A (ja) 1997-08-05

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