SK281510B6 - Polycyklická zlúčenina, spôsob jej výroby, farmaceutický prostriedok s jej obsahom, jej použitie a biologicky čistá kultúra - Google Patents

Polycyklická zlúčenina, spôsob jej výroby, farmaceutický prostriedok s jej obsahom, jej použitie a biologicky čistá kultúra Download PDF

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Publication number
SK281510B6
SK281510B6 SK539-96A SK53996A SK281510B6 SK 281510 B6 SK281510 B6 SK 281510B6 SK 53996 A SK53996 A SK 53996A SK 281510 B6 SK281510 B6 SK 281510B6
Authority
SK
Slovakia
Prior art keywords
compound
compounds
medium
ppm
nodulisporium
Prior art date
Application number
SK539-96A
Other languages
English (en)
Slovak (sk)
Other versions
SK53996A3 (en
Inventor
Anne W. Dombrowski
Richard G. Endris
Gregory L. Helms
Otto D. Hensens
John G. Ondeyka
Dan A. Ostlind
Jon D. Polishook
Deborah L. Zink
Original Assignee
Merck & Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co., Inc. filed Critical Merck & Co., Inc.
Publication of SK53996A3 publication Critical patent/SK53996A3/sk
Publication of SK281510B6 publication Critical patent/SK281510B6/sk

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Microbiology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Steroid Compounds (AREA)
SK539-96A 1993-11-01 1994-10-27 Polycyklická zlúčenina, spôsob jej výroby, farmaceutický prostriedok s jej obsahom, jej použitie a biologicky čistá kultúra SK281510B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/146,638 US5399582A (en) 1993-11-01 1993-11-01 Antiparasitic agents
PCT/US1994/012302 WO1995012599A1 (en) 1993-11-01 1994-10-27 Polycyclic antiparasitic agents, process and strain for their preparation and their use

Publications (2)

Publication Number Publication Date
SK53996A3 SK53996A3 (en) 1997-03-05
SK281510B6 true SK281510B6 (sk) 2001-04-09

Family

ID=22518283

Family Applications (1)

Application Number Title Priority Date Filing Date
SK539-96A SK281510B6 (sk) 1993-11-01 1994-10-27 Polycyklická zlúčenina, spôsob jej výroby, farmaceutický prostriedok s jej obsahom, jej použitie a biologicky čistá kultúra

Country Status (24)

Country Link
US (2) US5399582A (ja)
EP (1) EP0726902B1 (ja)
JP (1) JP3557212B2 (ja)
KR (1) KR100333017B1 (ja)
CN (2) CN1046943C (ja)
AT (1) ATE188476T1 (ja)
AU (1) AU688405B2 (ja)
CA (1) CA2174645C (ja)
CZ (1) CZ286032B6 (ja)
DE (1) DE69422526T2 (ja)
DK (1) DK0726902T3 (ja)
ES (1) ES2143558T3 (ja)
FI (2) FI110871B (ja)
GR (1) GR3032493T3 (ja)
HU (1) HU221276B1 (ja)
NO (1) NO315942B1 (ja)
NZ (1) NZ275339A (ja)
PL (1) PL178879B1 (ja)
PT (1) PT726902E (ja)
RU (1) RU2139874C1 (ja)
SI (1) SI0726902T1 (ja)
SK (1) SK281510B6 (ja)
WO (1) WO1995012599A1 (ja)
ZA (1) ZA948542B (ja)

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Also Published As

Publication number Publication date
WO1995012599A1 (en) 1995-05-11
EP0726902A1 (en) 1996-08-21
PT726902E (pt) 2000-06-30
PL314190A1 (en) 1996-09-02
NO961748L (no) 1996-07-01
FI961839A (fi) 1996-04-30
PL178879B1 (pl) 2000-06-30
HUT74959A (en) 1997-03-28
KR100333017B1 (ko) 2002-09-27
JP3557212B2 (ja) 2004-08-25
FI110871B (fi) 2003-04-15
NZ275339A (en) 1997-11-24
CN1137796A (zh) 1996-12-11
GR3032493T3 (en) 2000-05-31
CA2174645A1 (en) 1995-05-11
SI0726902T1 (en) 2000-04-30
RU2139874C1 (ru) 1999-10-20
CN1236012A (zh) 1999-11-24
FI112503B (fi) 2003-12-15
KR960705828A (ko) 1996-11-08
ATE188476T1 (de) 2000-01-15
ZA948542B (en) 1995-06-27
NO961748D0 (no) 1996-04-30
EP0726902B1 (en) 2000-01-05
NO315942B1 (no) 2003-11-17
US5614546A (en) 1997-03-25
HU221276B1 (en) 2002-09-28
ES2143558T3 (es) 2000-05-16
JPH09505567A (ja) 1997-06-03
AU8092994A (en) 1995-05-23
CZ286032B6 (cs) 1999-12-15
HU9601138D0 (en) 1996-06-28
CZ124996A3 (en) 1996-10-16
US5399582A (en) 1995-03-21
DE69422526T2 (de) 2000-07-27
DK0726902T3 (da) 2000-05-01
CA2174645C (en) 2004-09-07
CN1082543C (zh) 2002-04-10
FI961839A0 (fi) 1996-04-30
AU688405B2 (en) 1998-03-12
SK53996A3 (en) 1997-03-05
CN1046943C (zh) 1999-12-01
FI20012318A (fi) 2001-11-27
DE69422526D1 (de) 2000-02-10

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