ATE188476T1 - Polyzyklische antiparasitäre derivate, verfahren und stamm zu ihrer herstellung und ihrer verwendung - Google Patents

Polyzyklische antiparasitäre derivate, verfahren und stamm zu ihrer herstellung und ihrer verwendung

Info

Publication number
ATE188476T1
ATE188476T1 AT94932063T AT94932063T ATE188476T1 AT E188476 T1 ATE188476 T1 AT E188476T1 AT 94932063 T AT94932063 T AT 94932063T AT 94932063 T AT94932063 T AT 94932063T AT E188476 T1 ATE188476 T1 AT E188476T1
Authority
AT
Austria
Prior art keywords
strain
antiparasite
polycyclic
derivatives
production
Prior art date
Application number
AT94932063T
Other languages
English (en)
Inventor
Anne W Dombrowski
Richard G Endris
Gregory L Helms
Otto D Hensens
John G Ondeyka
Dan A Ostlind
Jon D Polishook
Deborah L Zink
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of ATE188476T1 publication Critical patent/ATE188476T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
    • C07D491/16—Peri-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/22—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains four or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
AT94932063T 1993-11-01 1994-10-27 Polyzyklische antiparasitäre derivate, verfahren und stamm zu ihrer herstellung und ihrer verwendung ATE188476T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/146,638 US5399582A (en) 1993-11-01 1993-11-01 Antiparasitic agents
PCT/US1994/012302 WO1995012599A1 (en) 1993-11-01 1994-10-27 Polycyclic antiparasitic agents, process and strain for their preparation and their use

Publications (1)

Publication Number Publication Date
ATE188476T1 true ATE188476T1 (de) 2000-01-15

Family

ID=22518283

Family Applications (1)

Application Number Title Priority Date Filing Date
AT94932063T ATE188476T1 (de) 1993-11-01 1994-10-27 Polyzyklische antiparasitäre derivate, verfahren und stamm zu ihrer herstellung und ihrer verwendung

Country Status (24)

Country Link
US (2) US5399582A (de)
EP (1) EP0726902B1 (de)
JP (1) JP3557212B2 (de)
KR (1) KR100333017B1 (de)
CN (2) CN1046943C (de)
AT (1) ATE188476T1 (de)
AU (1) AU688405B2 (de)
CA (1) CA2174645C (de)
CZ (1) CZ286032B6 (de)
DE (1) DE69422526T2 (de)
DK (1) DK0726902T3 (de)
ES (1) ES2143558T3 (de)
FI (2) FI110871B (de)
GR (1) GR3032493T3 (de)
HU (1) HU221276B1 (de)
NO (1) NO315942B1 (de)
NZ (1) NZ275339A (de)
PL (1) PL178879B1 (de)
PT (1) PT726902E (de)
RU (1) RU2139874C1 (de)
SI (1) SI0726902T1 (de)
SK (1) SK281510B6 (de)
WO (1) WO1995012599A1 (de)
ZA (1) ZA948542B (de)

Families Citing this family (74)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399582A (en) * 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents
US5541208A (en) * 1994-01-24 1996-07-30 Merck & Co., Inc. Indole diterpene alkaloid compounds
US5962499A (en) * 1995-03-20 1999-10-05 Merck & Co., Inc. Nodulisporic acid derivatives
US6221894B1 (en) 1995-03-20 2001-04-24 Merck & Co., Inc. Nodulisporic acid derivatives
US5595991A (en) * 1995-03-20 1997-01-21 Merck & Co., Inc. Anthelmintic use of nodulisporic acid and analogs thereof
JP3020279B2 (ja) * 1995-03-20 2000-03-15 メルク エンド カンパニー インコーポレーテッド ノジュリスポル酸誘導体
US5834260A (en) * 1996-08-30 1998-11-10 Merck & Co., Inc. Antiparasitic agents
ATE234841T1 (de) * 1996-09-19 2003-04-15 Merck & Co Inc Nodulisporinsäurederivate
AU1155499A (en) * 1997-10-09 1999-05-03 Rhone-Poulenc Agro Pesticidal combination
ES2359973T3 (es) 1998-03-19 2011-05-30 MERCK SHARP & DOHME CORP. Composiciones poliméricas líquidas para la liberación controlada de sustancias bioactivas.
US6787342B2 (en) 2000-02-16 2004-09-07 Merial Limited Paste formulations
US6586452B1 (en) 2000-07-14 2003-07-01 Merck & Co., Inc. C1 to C4 side chain modified nodulisporic acid analogs
US6399786B1 (en) * 2000-07-14 2002-06-04 Merck & Co., Inc. Nonacyclic nodulisporic acid derivatives
US20040077703A1 (en) * 2002-10-02 2004-04-22 Soll Mark D. Nodulisporic acid derivative spot-on formulations for combating parasites
US8362086B2 (en) 2005-08-19 2013-01-29 Merial Limited Long acting injectable formulations
NZ573758A (en) 2006-07-05 2012-01-12 Aventis Agriculture 1-Phenyl-3-cyano-pyrazole derivatives and pesticidal formulations containing them
SI2639228T1 (sl) 2007-05-15 2017-03-31 Merial, Inc. Ariloazol-2-il cianoetilamino spojine, postopek njihove izdelave in postopek njihove uporabe
TWI556741B (zh) 2007-08-17 2016-11-11 英特威特國際股份有限公司 異唑啉組成物及其作為抗寄生蟲藥上的應用
ES2584930T3 (es) 2007-12-21 2016-09-30 Merial Limited El uso de compuestos de 6-halógeno-(1,2,4)-triazolo-(1,5-a)-pirimidina para combatir plagas en y sobre animales
ME03409B (de) 2008-11-14 2020-01-20 Merial Inc Mit enantiomeren angereicherte, parasitentötende aryloazol-2-yl-cyanoethylamino-verbindungen
EP2364147A2 (de) 2008-11-19 2011-09-14 Merial Limited Zusammensetzungen mit 1-arylpyrazol allein oder in kombination mit formamidin zur behandlung von parasiteninfektionen
ES2537424T3 (es) 2008-12-04 2015-06-08 Merial Limited Derivados de dímeros de avermectina y de milbemicina
NZ597929A (en) 2009-07-30 2013-09-27 Merial Ltd Insecticidal 4-amino-thieno[2,3-d]-pyrimidine compounds and methods of their use
CA2782902C (en) 2009-12-04 2017-10-17 Merial Limited Pesticidal bis-organosulfur compounds
WO2011075591A1 (en) 2009-12-17 2011-06-23 Merial Limited Anti parasitic dihydroazole compounds and compositions comprising same
EP2512467A1 (de) 2009-12-17 2012-10-24 Merial Limited Zusammensetzung mit makrocyclischen lactonverbindungen undspirodioxepinoindolen
US20120295931A1 (en) 2010-02-05 2012-11-22 Lutz Juergen Spiroindoline compounds for use as anthelminthics
UA108641C2 (uk) 2010-04-02 2015-05-25 Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування
HUE034347T2 (en) 2010-09-29 2018-02-28 Intervet Int Bv N-heteroaryl compounds with a cyclic bridge unit for the treatment of parasitic diseases
KR101916481B1 (ko) 2010-09-29 2018-11-07 인터벳 인터내셔널 비.브이. Ｎ-헤테로아릴 화합물
CA2818563C (en) 2010-11-16 2019-11-12 Merial Limited Monensin derivatives for the treatment and prevention of protozoal infections.
CN103619818A (zh) 2011-06-20 2014-03-05 纳幕尔杜邦公司 用于治疗蠕虫感染的杂环化合物
WO2013003168A1 (en) 2011-06-27 2013-01-03 Merial Limited Novel insect-repellent coumarin derivatives, syntheses, and methods of use
US8946270B2 (en) 2011-06-27 2015-02-03 Merial Limited Amido-pyridyl ether compounds and compositions and their use against parasites
EP2739626B1 (de) 2011-08-04 2016-05-04 Intervet International B.V. Neue spiroindolinverbindungen
HUE052594T2 (hu) 2011-09-12 2021-05-28 Boehringer Ingelheim Animal Health Usa Inc Izoxazolint tartalmazó parazita-ellenes készítmények, ezek elõállítása és alkalmazása
US20130079394A1 (en) 2011-09-23 2013-03-28 Cnrs (Centre National Recherche Scientifique) Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods
MX368738B (es) 2011-11-17 2019-10-14 Boehringer Ingelheim Animal Health Usa Inc Composiciones que comprenden un aril pirazol y un imidazol sustituido, metodos y usos de las mismas.
CN103958476A (zh) 2011-11-28 2014-07-30 纳幕尔杜邦公司 N-(4-喹啉基甲基)磺酰胺衍生物以及它们作为驱肠虫剂的用途
PT2785719T (pt) 2011-12-02 2018-02-08 Merial Inc Formulações injetáveis de moxidectina de ação prolongada e novas formas cristalinas de moxidectina
PL232463B1 (pl) 2012-02-06 2019-06-28 Merial Inc Miękka, nadająca się do żucia kompozycja weterynaryjna do leczenia i/lub zapobiegania infekcji lub inwazji pasożytniczej u zwierzęcia oraz jej zastosowanie
JO3626B1 (ar) 2012-02-23 2020-08-27 Merial Inc تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها
US9260441B2 (en) 2012-03-28 2016-02-16 Intervet Inc. Heteroaryl compounds with cyclic bridging unit
US9321724B2 (en) 2012-03-28 2016-04-26 Intervet Inc. Heteroaryl compounds with A-cyclic bridging unit
UA115981C2 (uk) 2012-04-20 2018-01-25 Меріал, Інк. Паразитицидні композиції, що містять похідні бензимідазолу, способи їх одержання та застосування
NZ723198A (en) 2012-11-20 2018-11-30 Boehringer Ingelheim Animal Health Usa Inc Anthelmintic compounds and compositions and methods of using thereof
WO2014099837A1 (en) 2012-12-18 2014-06-26 E. I. Du Pont De Nemours And Company Sulfonamide anthelmintics
EP3063144B1 (de) 2013-11-01 2021-09-08 Boehringer Ingelheim Animal Health USA Inc. Antiparasitäre und pestizide isoxazolinverbindungen
NZ726251A (en) 2014-04-17 2017-11-24 Merial Inc Use of malononitrile compounds for protecting animals from parasites
AU2015264336B2 (en) 2014-05-19 2018-08-30 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic compounds
ES2895826T3 (es) 2014-06-19 2022-02-22 Boehringer Ingelheim Animal Health Usa Inc Composiciones parasiticidas que comprenden derivados de indol, procedimientos y usos de las mismas
WO2016069983A1 (en) 2014-10-31 2016-05-06 Merial, Inc. Parasiticidal composition comprising fipronil
UY36570A (es) 2015-02-26 2016-10-31 Merial Inc Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas
PT3298027T (pt) 2015-05-20 2022-01-26 Boehringer Ingelheim Animal Health Usa Inc Compostos depsipéptidos antelmínticos
UY37137A (es) 2016-02-24 2017-09-29 Merial Inc Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos
WO2018039508A1 (en) 2016-08-25 2018-03-01 Merial, Inc. Method for reducing unwanted effects in parasiticidal treatments
EP3525590A1 (de) 2016-10-14 2019-08-21 Boehringer Ingelheim Animal Health USA Inc. Pestizide und parasitizide vinylisoxazolinverbindungen
BR112019009977A2 (pt) 2016-11-16 2019-08-27 Boehringer Ingelheim Animal Health Usa Inc compostos depsipeptídicos anti-helmínticos
AR111260A1 (es) 2017-03-31 2019-06-19 Intervet Int Bv Formulación farmacéutica de la sal de crotonil amino piridina
WO2019036407A1 (en) 2017-08-14 2019-02-21 Merial, Inc. PYRAZOLE-ISOXAZOLINE COMPOUNDS WITH PESTICIDE AND PARASITICIDE ACTIVITY
EP3688174A4 (de) 2017-09-29 2021-09-08 Victoria Link Limited Heterologe biosynthese von nodulisporsäure
US11583545B2 (en) 2018-02-08 2023-02-21 Boehringer Ingelheim Animal Health USA Inc. Parasiticidal compositions comprising eprinomectin and praziquantel, methods and uses thereof
WO2020002593A1 (en) 2018-06-29 2020-01-02 Intervet International B.V. Compound for use against helminthic infection
US20220048903A1 (en) 2018-07-09 2022-02-17 Boehringer Ingelheim Animal Health USA Inc. Anthelminthic Heterocyclic Compounds
WO2020112374A1 (en) 2018-11-20 2020-06-04 Boehringer Ingelheim Animal Health USA Inc. Indazolylcyanoethylamino compound, compositions of same, method of making, and methods of using thereof
AU2020208145B2 (en) 2019-01-16 2023-02-02 Boehringer Ingelheim Vetmedica Gmbh Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof
BR112021016196A2 (pt) 2019-03-01 2021-10-05 Boehringer Ingelheim Animal Health USA Inc. Composições injetáveis de clorsulon, métodos e usos das mesmas
CA3133100A1 (en) 2019-03-19 2020-09-24 Boehringer Ingelheim Animal Health USA Inc. Anthelmintic aza-benzothiophene and aza-benzofuran compounds
MX2022007670A (es) 2019-12-18 2022-07-19 Intervet Int Bv Compuestos antihelminticos que comprenden una estructura de quinolina.
EP4077322A1 (de) 2019-12-18 2022-10-26 Intervet International B.V. Anthelmintische verbindungen mit azaindolstruktur
JP2023528822A (ja) 2020-05-29 2023-07-06 ベーリンガー インゲルハイム アニマル ヘルス ユーエスエイ インコーポレイテッド 駆虫性複素環式化合物
EP4259636A1 (de) 2020-12-11 2023-10-18 Intervet International B.V. Anthelmintische verbindungen mit einer thienopyridinstruktur
AU2021410052A1 (en) 2020-12-21 2023-08-03 Boehringer Ingelheim Vetmedica Gmbh Parasiticidal collar comprising isoxazoline compounds
US20230312207A1 (en) 2022-02-17 2023-10-05 Boehringer Ingelheim Vetmedica Gmbh Method and system for providing a fluid product mailer

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE434277B (sv) * 1976-04-19 1984-07-16 Merck & Co Inc Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis
US4199569A (en) * 1977-10-03 1980-04-22 Merck & Co., Inc. Selective hydrogenation products of C-076 compounds and derivatives thereof
DE3611168C2 (de) * 1985-04-02 1994-01-20 Asahi Chemical Ind Hydroxybenzoesäurephenylester, deren Herstellung und deren Verwendung als physiologisch wirksame Substanzen
JP2805564B2 (ja) * 1992-08-13 1998-09-30 明治製菓株式会社 新規物質ｐｆ１１０１ｂ物質及びその製造法
US5399582A (en) * 1993-11-01 1995-03-21 Merck & Co., Inc. Antiparasitic agents

Also Published As

Publication number Publication date
CN1137796A (zh) 1996-12-11
AU688405B2 (en) 1998-03-12
SI0726902T1 (en) 2000-04-30
US5399582A (en) 1995-03-21
NZ275339A (en) 1997-11-24
NO961748L (no) 1996-07-01
CZ286032B6 (cs) 1999-12-15
US5614546A (en) 1997-03-25
WO1995012599A1 (en) 1995-05-11
GR3032493T3 (en) 2000-05-31
SK53996A3 (en) 1997-03-05
ES2143558T3 (es) 2000-05-16
DE69422526T2 (de) 2000-07-27
JP3557212B2 (ja) 2004-08-25
CN1082543C (zh) 2002-04-10
SK281510B6 (sk) 2001-04-09
FI20012318A (fi) 2001-11-27
FI961839A (fi) 1996-04-30
DK0726902T3 (da) 2000-05-01
FI110871B (fi) 2003-04-15
PL178879B1 (pl) 2000-06-30
CA2174645C (en) 2004-09-07
DE69422526D1 (de) 2000-02-10
EP0726902B1 (de) 2000-01-05
HU221276B1 (en) 2002-09-28
NO961748D0 (no) 1996-04-30
HU9601138D0 (en) 1996-06-28
CN1046943C (zh) 1999-12-01
EP0726902A1 (de) 1996-08-21
AU8092994A (en) 1995-05-23
JPH09505567A (ja) 1997-06-03
HUT74959A (en) 1997-03-28
CN1236012A (zh) 1999-11-24
KR960705828A (ko) 1996-11-08
ZA948542B (en) 1995-06-27
CA2174645A1 (en) 1995-05-11
PL314190A1 (en) 1996-09-02
KR100333017B1 (ko) 2002-09-27
PT726902E (pt) 2000-06-30
NO315942B1 (no) 2003-11-17
FI112503B (fi) 2003-12-15
RU2139874C1 (ru) 1999-10-20
CZ124996A3 (en) 1996-10-16
FI961839A0 (fi) 1996-04-30

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