SK280199B6 - Fragment dna(h) kódujúci polypeptid s nitril-hydra - Google Patents

Fragment dna(h) kódujúci polypeptid s nitril-hydra Download PDF

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Publication number
SK280199B6
SK280199B6 SK531-91A SK53191A SK280199B6 SK 280199 B6 SK280199 B6 SK 280199B6 SK 53191 A SK53191 A SK 53191A SK 280199 B6 SK280199 B6 SK 280199B6
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SK
Slovakia
Prior art keywords
dna
nitrile hydratase
transformant
fragment
mixture
Prior art date
Application number
SK531-91A
Other languages
English (en)
Slovak (sk)
Inventor
Beppu Teruhiko
Yamada Hideaki
Nagasawa Toru
Horinouchi Sueharu
Nishiyama Nakoto
Original Assignee
Mitsubishi Rayon Co.
Beppu Teruhiko
Yamada Hideaki
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mitsubishi Rayon Co., Beppu Teruhiko, Yamada Hideaki filed Critical Mitsubishi Rayon Co.
Publication of SK280199B6 publication Critical patent/SK280199B6/sk

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/78—Hydrolases (3) acting on carbon to nitrogen bonds other than peptide bonds (3.5)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
SK531-91A 1990-02-28 1991-02-28 Fragment dna(h) kódujúci polypeptid s nitril-hydra SK280199B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4807890 1990-02-28
US08/028,463 US5731176A (en) 1990-02-28 1993-03-09 DNA fragment encoding a polypeptide having nitrile hydratase activity, a transformant containing the gene and a process for the production of amides using the transformant

Publications (1)

Publication Number Publication Date
SK280199B6 true SK280199B6 (sk) 1999-09-10

Family

ID=26388301

Family Applications (1)

Application Number Title Priority Date Filing Date
SK531-91A SK280199B6 (sk) 1990-02-28 1991-02-28 Fragment dna(h) kódujúci polypeptid s nitril-hydra

Country Status (18)

Country Link
US (1) US5731176A (zh)
EP (1) EP0445646B1 (zh)
JP (1) JP3162091B2 (zh)
KR (1) KR950002004B1 (zh)
CN (1) CN1054639C (zh)
AT (1) ATE138101T1 (zh)
AU (1) AU627648B2 (zh)
CA (1) CA2037291C (zh)
CZ (2) CZ284048B6 (zh)
DE (1) DE69119454T2 (zh)
DK (1) DK0445646T3 (zh)
ES (1) ES2089044T3 (zh)
FI (1) FI102539B1 (zh)
MX (1) MX193790B (zh)
NO (1) NO306684B1 (zh)
PL (1) PL166201B1 (zh)
RU (1) RU2081173C1 (zh)
SK (1) SK280199B6 (zh)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2907479B2 (ja) * 1990-02-28 1999-06-21 輝彦 別府 ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、これを含有する形質転換体及びアミド類の製造法
EP0502476B1 (en) * 1991-03-04 2001-07-18 Mitsubishi Rayon Co., Ltd. Hybrid plasmid vectors containing genes encoding nitrile degrading enzymes and methods of producing amides and acids
AU3692593A (en) * 1992-04-28 1993-11-04 Mitsubishi Kasei Corporation Novel protein having nitrile hydratase activity and the gene encoding the same, and a method for producing amides from nitriles via a transformant containing the gene
JP3828590B2 (ja) * 1994-10-03 2006-10-04 昌 清水 ニトリルヒドラターゼ遺伝子発現のための調節遺伝子
JP3154633B2 (ja) * 1994-12-28 2001-04-09 三菱レイヨン株式会社 ニトリラーゼ遺伝子発現のための調節因子およびその遺伝子
AU7514896A (en) * 1995-10-06 1997-04-28 E.I. Du Pont De Nemours And Company Nucleic acid fragments encoding stereospecific nitrile hydratase and amidase enzymes and recombinant microorganisms expressing those enzymes useful for the production of chiral amides and acides
CN1101470C (zh) * 1996-02-14 2003-02-12 三井东压化学株式会社 新型腈水合酶
US5866379A (en) * 1997-01-28 1999-02-02 Novus International Enzymatic conversion of α-hydroxynitriles to the corresponding .alpha.
FR2770214B1 (fr) * 1997-10-24 1999-12-31 Rhodia Chimie Sa Procede de preparation d'un benzamide halogene
JP2000050866A (ja) * 1998-08-06 2000-02-22 Rikagaku Kenkyusho ニトリルヒドラターゼの生産方法
JP4185607B2 (ja) 1998-12-15 2008-11-26 ダイセル化学工業株式会社 新規な微生物及びアミド化合物の製造方法
CN1340101A (zh) * 1999-10-26 2002-03-13 昭和电工株式会社 新型红球菌属细菌、源自于红球菌属细菌的腈水解酶基因、腈水合酶基因和酰胺酶基因,以及利用它们生产羧酸的方法
RU2288270C2 (ru) 2000-12-20 2006-11-27 Диа-Нитрикс Ко., Лтд. Способ производства амидного соединения с применением микробного катализатора
PT1352050E (pt) * 2001-01-09 2009-03-24 Lonza Ag Processo microbiológico para a produção de amidas
JP2002325587A (ja) * 2001-03-02 2002-11-12 Daicel Chem Ind Ltd ニトリルヒドラターゼ、およびアミドの製造方法
JP2004194588A (ja) 2002-12-19 2004-07-15 Mitsui Chemicals Inc 新規なニトリルヒドラターゼ
WO2004067738A2 (en) * 2003-01-27 2004-08-12 Degussa Ag Nitrile hydratases from rhodococcus erythropolis and their application
SG148992A1 (en) 2003-12-02 2009-01-29 Ciba Spec Chem Water Treat Ltd Strain of rhodococcus rhodochrous ncimb 41164 and its use as producer of nitrile hydratase
CN103146670B (zh) * 2004-05-26 2014-11-26 Dia-Nitrix株式会社 改良型腈水合酶
JP2006187257A (ja) 2005-01-07 2006-07-20 Daiyanitorikkusu Kk アミド化合物の製造方法およびアクリルアミド系ポリマー
EP1842907A1 (en) 2006-04-07 2007-10-10 B.R.A.I.N. Ag A group of novel enantioselective microbial nitrile hydratases with broad substrate specificity
WO2008004473A1 (fr) * 2006-07-06 2008-01-10 University Of Tsukuba Nouveau complexe de protéines, procédé de maturation de nitrile hydratase à faible poids moléculaire de type au cobalt utilisant le complexe de protéines, nitrile hydratase correspondante et procédé l'utilisant
WO2008056827A1 (en) 2006-11-09 2008-05-15 Mitsubishi Rayon Co., Ltd. Process for production of betaine
AU2012264058B2 (en) 2011-05-31 2015-10-22 Mitsubishi Chemical Corporation Improved nitrile hydratase
US9193966B2 (en) 2011-06-07 2015-11-24 Mitsubishi Rayon Co., Ltd. Nitrile hydratase
FR3002542B1 (fr) * 2013-02-28 2016-01-22 Servier Lab Procede de synthese enzymatique de l'acide (7s) 3,4-dimethoxybicyclo[4.2.0]octa-1,3,5-triene 7-carboxylique et application a la synthese de l'ivabradine et de ses sels
KR101995103B1 (ko) * 2014-06-06 2019-07-03 미쯔비시 케미컬 주식회사 개량형 니트릴 히드라타제
EP3535386A4 (en) * 2016-11-04 2020-04-15 Georgia State University Research Foundation, Inc. ENDOTOXIN-FREE ASPARAGINASE
CN116888269A (zh) 2021-02-10 2023-10-13 三菱化学株式会社 用醛提高腈水合酶的反应性
CN114934006A (zh) * 2022-06-02 2022-08-23 无锡新晨宇生物工程有限公司 一种腈水合酶催化乙腈生成乙酰胺的应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD274631A5 (de) * 1987-09-18 1989-12-27 Kk Verfahren zur biologischen herstellung von amiden
JP2840253B2 (ja) * 1988-07-06 1998-12-24 輝彦 別府 ニトリルヒドラターゼ活性を有するポリペプチドをコードする遺伝子ｄｎａ、これを含有する形質転換体によるニトリル類からアミド類の製造法

Also Published As

Publication number Publication date
CZ284017B6 (cs) 1998-07-15
CN1054639C (zh) 2000-07-19
JPH04211379A (ja) 1992-08-03
ATE138101T1 (de) 1996-06-15
DK0445646T3 (da) 1996-09-30
MX193790B (en) 1999-10-19
CS9100531A2 (en) 1991-10-15
KR910021473A (ko) 1991-12-20
RU2081173C1 (ru) 1997-06-10
NO910797D0 (no) 1991-02-27
CZ284048B6 (cs) 1998-07-15
CZ317094A3 (cs) 1998-05-13
NO306684B1 (no) 1999-12-06
EP0445646A2 (en) 1991-09-11
KR950002004B1 (ko) 1995-03-08
CA2037291C (en) 2001-07-24
PL289239A1 (en) 1992-03-23
FI910960A (fi) 1991-08-29
AU7129391A (en) 1991-09-12
AU627648B2 (en) 1992-08-27
FI102539B (fi) 1998-12-31
CA2037291A1 (en) 1991-08-29
DE69119454T2 (de) 1996-09-26
CN1054616A (zh) 1991-09-18
ES2089044T3 (es) 1996-10-01
PL166201B1 (pl) 1995-04-28
JP3162091B2 (ja) 2001-04-25
NO910797L (no) 1991-08-29
EP0445646B1 (en) 1996-05-15
EP0445646A3 (en) 1992-01-08
DE69119454D1 (de) 1996-06-20
US5731176A (en) 1998-03-24
FI910960A0 (fi) 1991-02-27
FI102539B1 (fi) 1998-12-31

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