SK278447B6 - Method for preparing 1-phenylimidazolin-2,5-dione derivatives - Google Patents

Method for preparing 1-phenylimidazolin-2,5-dione derivatives Download PDF

Info

Publication number
SK278447B6
SK278447B6 SK6567-90A SK656790A SK278447B6 SK 278447 B6 SK278447 B6 SK 278447B6 SK 656790 A SK656790 A SK 656790A SK 278447 B6 SK278447 B6 SK 278447B6
Authority
SK
Slovakia
Prior art keywords
oxide
copper
catalyst
reaction
hydrogen atom
Prior art date
Application number
SK6567-90A
Other languages
English (en)
Slovak (sk)
Other versions
SK656790A3 (en
Inventor
Patrick Seuron
Daniel Varraillon
Original Assignee
Patrick Seuron
Daniel Varraillon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Patrick Seuron, Daniel Varraillon filed Critical Patrick Seuron
Publication of SK656790A3 publication Critical patent/SK656790A3/sk
Publication of SK278447B6 publication Critical patent/SK278447B6/sk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Reinforced Plastic Materials (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
SK6567-90A 1989-12-22 1990-12-21 Method for preparing 1-phenylimidazolin-2,5-dione derivatives SK278447B6 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8917046A FR2656302B1 (fr) 1989-12-22 1989-12-22 Nouveau procede de preparation de l'anandron et derives de l'anandron.

Publications (2)

Publication Number Publication Date
SK656790A3 SK656790A3 (en) 1997-06-04
SK278447B6 true SK278447B6 (en) 1997-06-04

Family

ID=9388859

Family Applications (1)

Application Number Title Priority Date Filing Date
SK6567-90A SK278447B6 (en) 1989-12-22 1990-12-21 Method for preparing 1-phenylimidazolin-2,5-dione derivatives

Country Status (24)

Country Link
US (1) US5166358A (ja)
EP (1) EP0436426B1 (ja)
JP (1) JP2836041B2 (ja)
KR (1) KR0173307B1 (ja)
CN (1) CN1048011C (ja)
AT (1) ATE107289T1 (ja)
AU (1) AU628699B2 (ja)
CA (1) CA2032988C (ja)
CZ (1) CZ281655B6 (ja)
DE (1) DE69009964T2 (ja)
DK (1) DK0436426T3 (ja)
ES (1) ES2055382T3 (ja)
FI (1) FI103203B1 (ja)
FR (1) FR2656302B1 (ja)
HU (1) HU207301B (ja)
IE (1) IE65510B1 (ja)
IL (1) IL96696A (ja)
NZ (1) NZ236621A (ja)
PL (1) PL164694B1 (ja)
PT (1) PT96313B (ja)
RU (1) RU1836356C (ja)
SK (1) SK278447B6 (ja)
UA (1) UA27220C2 (ja)
ZA (1) ZA909648B (ja)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2693461B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5656651A (en) * 1995-06-16 1997-08-12 Biophysica Inc. Androgenic directed compositions
FR2741346B1 (fr) * 1995-11-16 1997-12-19 Roussel Uclaf Nouveau procede de preparation de derives phenylimidazolidine
FR2741342B1 (fr) * 1995-11-22 1998-02-06 Roussel Uclaf Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
JPH1072446A (ja) * 1996-06-24 1998-03-17 Sumitomo Chem Co Ltd １−置換−ヒダントイン類の製造法
EP1299094A2 (en) * 2000-06-28 2003-04-09 Bristol-Myers Squibb Company Selective androgen receptor modulators and methods for their identification, design and use
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
ATE502298T1 (de) * 2003-12-19 2011-04-15 Univ California Verfahren und materialien zur beurteilung von prostatakrebstherapien
WO2005099693A2 (en) * 2004-02-24 2005-10-27 The Regents Of The University Of California Methods and materials for assessing prostate cancer therapies and compounds
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
EP2656841B1 (en) * 2006-03-27 2016-08-10 The Regents of The University of California Androgen receptor modulator for the treatment of prostate cancer and androgen receptor-associated diseases
CN102755318B (zh) 2006-03-29 2014-09-10 加利福尼亚大学董事会 二芳基硫代乙内酰脲化合物
JP5535925B2 (ja) 2007-10-26 2014-07-02 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア アンドロゲン受容体調節物質としてのジアリールヒダントイン化合物
SI3124481T1 (en) 2010-02-16 2018-06-29 Aragon Pharmaceuticals, Inc. Androgen receptor modulators and their use
SI3305285T1 (sl) 2012-09-26 2021-03-31 Aragon Pharmaceuticals, Inc. Anti-androgeni za zdravljenje proti kastraciji odpornega ne-metastatskega raka
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
JP7201694B2 (ja) 2017-10-16 2023-01-10 アラゴン ファーマシューティカルズ，インコーポレイテッド 非転移性去勢抵抗性前立腺癌の治療のための抗アンドロゲン剤

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH166004A (de) * 1934-06-06 1933-12-15 Chem Fab Vormals Sandoz Verfahren zur Darstellung eines Derivates des 5,5-Phenyläthylhydantoins.
US2490813A (en) * 1944-11-29 1949-12-13 Standard Oil Co Continuous process for making aryl amines
US2759002A (en) * 1954-03-24 1956-08-14 Abbott Lab 3-benzyl hydantoin and process
US3134663A (en) * 1957-07-23 1964-05-26 Geigy Chem Corp Herbicidal composition and method employing hydantoins
US3914311A (en) * 1973-06-15 1975-10-21 Du Pont Preparation of aromatic secondary and tertiary amines using a nickel complex catalyst
DE2414613A1 (de) * 1974-03-26 1975-10-16 Bayer Ag 1-aryl-5-alkyliden-2,4-dioxo-imidazolidine
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
IL55774A (en) * 1977-10-28 1982-04-30 Sparamedica Ag Pharmaceutical compositions containing urea derivatives,certain such novel derivatives and their manufacture
GB1598166A (en) * 1978-05-23 1981-09-16 Lilly Industries Ltd 3,5-disubstituted hydantoin derivatives
US4764625A (en) * 1980-12-12 1988-08-16 Xerox Corporation Process for preparing arylamines
DE3382406D1 (de) * 1982-04-08 1991-10-17 Shell Int Research Neue hydantoine, ihre herstellung und verwendung.

Also Published As

Publication number Publication date
ES2055382T3 (es) 1994-08-16
CN1048011C (zh) 2000-01-05
RU1836356C (ru) 1993-08-23
FI906366A0 (fi) 1990-12-21
SK656790A3 (en) 1997-06-04
KR910011799A (ko) 1991-08-07
FR2656302A1 (fr) 1991-06-28
CZ656790A3 (en) 1996-08-14
JPH04103573A (ja) 1992-04-06
FI906366A (fi) 1991-06-23
FR2656302B1 (fr) 1992-05-07
PL288365A1 (en) 1991-09-09
ATE107289T1 (de) 1994-07-15
US5166358A (en) 1992-11-24
AU628699B2 (en) 1992-09-17
PT96313B (pt) 1998-06-30
PL164694B1 (pl) 1994-09-30
FI103203B (fi) 1999-05-14
CA2032988A1 (fr) 1991-06-23
IL96696A (en) 1995-08-31
DE69009964D1 (de) 1994-07-21
UA27220C2 (uk) 2000-08-15
EP0436426A1 (fr) 1991-07-10
DE69009964T2 (de) 1994-10-13
DK0436426T3 (da) 1994-07-04
NZ236621A (en) 1992-04-28
IE65510B1 (en) 1995-11-01
CA2032988C (fr) 2003-04-29
KR0173307B1 (ko) 1999-02-01
EP0436426B1 (fr) 1994-06-15
ZA909648B (en) 1992-02-26
FI103203B1 (fi) 1999-05-14
IE904142A1 (en) 1991-07-03
CZ281655B6 (cs) 1996-12-11
HU207301B (en) 1993-03-29
AU6826590A (en) 1991-06-27
CN1052666A (zh) 1991-07-03
JP2836041B2 (ja) 1998-12-14
PT96313A (pt) 1991-09-30
IL96696A0 (en) 1991-09-16
HU908416D0 (en) 1991-07-29

Similar Documents

Publication Publication Date Title
SK278447B6 (en) Method for preparing 1-phenylimidazolin-2,5-dione derivatives
Uhle The synthesis of 5-keto-1, 3, 4, 5-tetrahydrobenz [cd] indole. A synthesis of 4-substituted indoles
Delia et al. Purine N-Oxides. XVII. The Oxidation of Guanine at Position 71
Brown Preparation of some new aminimides
KR910006125B1 (ko) 아세메타신의 제조방법
Gardner et al. The coupling of organic radicals by the action of Grignard reagents on heavy metal salts. II. Coupling of dissimilar radicals
JPS6150971A (ja) ２位で置換されたイミダゾ−ル−４，５−ジカルボン酸の製法
JPS60139657A (ja) 置換α‐ブロモアセトアミドの製法
Chauhan et al. The Preparation and Properties of Some 2, 1-Benzisoxazole and 2, 1-Benzisothiazole Derivatives
Považanec et al. The conversion of 5-nitrofurfuryl derivatives into 5-aminofurfurylidenemalonodinitrile
JPS5846514B2 (ja) ３−フエニルインド−ル誘導体の製造法
SK154294A3 (en) Method of production of 2,4,5-tribrompyrole-3-carbonitrile
KR890002425B1 (ko) 1-(하이드록시페닐)-3-메틸-4-디플루오로메틸-△²-1,2,4-트리아졸린-5-온 유도체의 제조방법
Koeppe et al. Syntheses of Some 2-Thiocyanoimidazoles1
US2451310A (en) Alkyl esters of alpha-acylamino, alpha-cyano, beta-(3 indole)-propionic acid
Birnbaum et al. Amines related to epinephrine. III. Amines of the eprocaine type
JPH0149323B2 (ja)
JPS6231713B2 (ja)
JPS63172771A (ja) インドアニリン系染料の製造法
GB2039885A (en) N-phenyl-N'-acyl-S- alkylisothiocarbamides
JPS62242672A (ja) １，２，４−トリアゾリン−５−オン誘導体及びその製法
Gorgos et al. Synthesis of 2-acylindoles from α-(N-isatinyl) ketones
JPH01207271A (ja) ４−ヒドロキシオリゴピリジン類の製造方法
JPS6023083B2 (ja) 新規ピリジルアゾ化合物及びその製造法
JPH04202187A (ja) フルジアゼパムの結晶化方法

Legal Events

Date Code Title Description
MK4A Patent expired

Expiry date: 20101221