PT96313A - Processo paraa preparacao de derivados da 1-fenil-imidazolino-2,5-diona - Google Patents

Processo paraa preparacao de derivados da 1-fenil-imidazolino-2,5-diona

Info

Publication number
PT96313A
PT96313A PT96313A PT9631390A PT96313A PT 96313 A PT96313 A PT 96313A PT 96313 A PT96313 A PT 96313A PT 9631390 A PT9631390 A PT 9631390A PT 96313 A PT96313 A PT 96313A
Authority
PT
Portugal
Prior art keywords
phenyl
imidazoline
preparation
diona
formula
Prior art date
Application number
PT96313A
Other languages
English (en)
Other versions
PT96313B (pt
Inventor
Patrick Seuron
Daniel Varraillon
Original Assignee
Roussel Uclaf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Roussel Uclaf filed Critical Roussel Uclaf
Publication of PT96313A publication Critical patent/PT96313A/pt
Publication of PT96313B publication Critical patent/PT96313B/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin
    • C07D233/74—Two oxygen atoms, e.g. hydantoin with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to other ring members
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/72—Two oxygen atoms, e.g. hydantoin

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Reinforced Plastic Materials (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
PT96313A 1989-12-22 1990-12-21 Processo paraa preparacao de derivados da 1-fenil-imidazolino-2,5-diona PT96313B (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8917046A FR2656302B1 (fr) 1989-12-22 1989-12-22 Nouveau procede de preparation de l'anandron et derives de l'anandron.

Publications (2)

Publication Number Publication Date
PT96313A true PT96313A (pt) 1991-09-30
PT96313B PT96313B (pt) 1998-06-30

Family

ID=9388859

Family Applications (1)

Application Number Title Priority Date Filing Date
PT96313A PT96313B (pt) 1989-12-22 1990-12-21 Processo paraa preparacao de derivados da 1-fenil-imidazolino-2,5-diona

Country Status (24)

Country Link
US (1) US5166358A (pt)
EP (1) EP0436426B1 (pt)
JP (1) JP2836041B2 (pt)
KR (1) KR0173307B1 (pt)
CN (1) CN1048011C (pt)
AT (1) ATE107289T1 (pt)
AU (1) AU628699B2 (pt)
CA (1) CA2032988C (pt)
CZ (1) CZ281655B6 (pt)
DE (1) DE69009964T2 (pt)
DK (1) DK0436426T3 (pt)
ES (1) ES2055382T3 (pt)
FI (1) FI103203B1 (pt)
FR (1) FR2656302B1 (pt)
HU (1) HU207301B (pt)
IE (1) IE65510B1 (pt)
IL (1) IL96696A (pt)
NZ (1) NZ236621A (pt)
PL (1) PL164694B1 (pt)
PT (1) PT96313B (pt)
RU (1) RU1836356C (pt)
SK (1) SK656790A3 (pt)
UA (1) UA27220C2 (pt)
ZA (1) ZA909648B (pt)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5411981A (en) * 1991-01-09 1995-05-02 Roussel Uclaf Phenylimidazolidines having antiandrogenic activity
FR2693461B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
FR2694290B1 (fr) * 1992-07-08 1994-09-02 Roussel Uclaf Nouvelles phénylimidazolidines éventuellement substituées, leur procédé de préparation, leur application comme médicaments et les compositions pharmaceutiques les renfermant.
US5656651A (en) * 1995-06-16 1997-08-12 Biophysica Inc. Androgenic directed compositions
FR2741346B1 (fr) * 1995-11-16 1997-12-19 Roussel Uclaf Nouveau procede de preparation de derives phenylimidazolidine
FR2741342B1 (fr) * 1995-11-22 1998-02-06 Roussel Uclaf Nouvelles phenylimidazolidines fluorees ou hydroxylees, procede, intermediaires de preparation, application comme medicaments, nouvelle utilisation et compositions pharmaceutiques
JPH1072446A (ja) * 1996-06-24 1998-03-17 Sumitomo Chem Co Ltd １−置換−ヒダントイン類の製造法
JP2004509072A (ja) * 2000-06-28 2004-03-25 ブリストル−マイヤーズ　スクイブ　カンパニー 選択的アンドロゲン受容体モジュレーター並びにその同定、設計及び使用方法
EP1854798A3 (en) 2000-09-19 2007-11-28 Bristol-Myers Squibb Company Fused heterocyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
US20040087548A1 (en) 2001-02-27 2004-05-06 Salvati Mark E. Fused cyclic succinimide compounds and analogs thereof, modulators of nuclear hormone receptor function
JP2007514442A (ja) * 2003-12-19 2007-06-07 ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア 前立腺癌治療を評価するための方法および物質
NZ550102A (en) * 2004-02-24 2010-10-29 Univ California Methods and materials for assessing prostate cancer therapies and compounds (thiohydantoine derivatives)
US7709517B2 (en) 2005-05-13 2010-05-04 The Regents Of The University Of California Diarylhydantoin compounds
HUE053877T2 (hu) 2006-03-27 2021-07-28 Univ California Androgén receptormodulátor a prosztatarák és az androgén receptorral összefüggõ betegségek kezeléséhez
NZ572374A (en) 2006-03-29 2011-12-22 Univ California Diarylthiohydantoin compounds
CA2703635C (en) 2007-10-26 2017-06-27 Michael E. Jung Diarylhydantoin compounds as androgen receptor modulators
CN106983749A (zh) 2010-02-16 2017-07-28 亚拉冈制药公司 雄激素受体调节剂及其用途
BR112015006705A8 (pt) 2012-09-26 2019-08-27 Aragon Pharmaceuticals Inc antiandrogênios para o tratamento de câncer de próstata resistente à castração não metastático e usos destes
JOP20200097A1 (ar) 2013-01-15 2017-06-16 Aragon Pharmaceuticals Inc معدل مستقبل أندروجين واستخداماته
TWI726969B (zh) 2016-01-11 2021-05-11 比利時商健生藥品公司 用作雄性激素受體拮抗劑之經取代之硫尿囊素衍生物
CA3079135A1 (en) 2017-10-16 2019-04-25 Arturo Molina Anti-androgens for the treatment of non-metastatic castration-resistant prostate cancer

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH166004A (de) * 1934-06-06 1933-12-15 Chem Fab Vormals Sandoz Verfahren zur Darstellung eines Derivates des 5,5-Phenyläthylhydantoins.
US2490813A (en) * 1944-11-29 1949-12-13 Standard Oil Co Continuous process for making aryl amines
US2759002A (en) * 1954-03-24 1956-08-14 Abbott Lab 3-benzyl hydantoin and process
US3134663A (en) * 1957-07-23 1964-05-26 Geigy Chem Corp Herbicidal composition and method employing hydantoins
US3914311A (en) * 1973-06-15 1975-10-21 Du Pont Preparation of aromatic secondary and tertiary amines using a nickel complex catalyst
DE2414613A1 (de) * 1974-03-26 1975-10-16 Bayer Ag 1-aryl-5-alkyliden-2,4-dioxo-imidazolidine
FR2329276A1 (fr) * 1975-10-29 1977-05-27 Roussel Uclaf Nouvelles imidazolidines substituees, procede de preparation, application comme medicament et compositions les renfermant
CA1138334A (en) * 1977-10-28 1982-12-28 Karl Bernauer Pharmaceutical preparations containing certain urea derivatives
GB1598166A (en) * 1978-05-23 1981-09-16 Lilly Industries Ltd 3,5-disubstituted hydantoin derivatives
US4764625A (en) * 1980-12-12 1988-08-16 Xerox Corporation Process for preparing arylamines
EP0091596B1 (de) * 1982-04-08 1991-09-11 Shell Internationale Researchmaatschappij B.V. Neue Hydantoine, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
CZ281655B6 (cs) 1996-12-11
KR910011799A (ko) 1991-08-07
IL96696A0 (en) 1991-09-16
CN1048011C (zh) 2000-01-05
CA2032988A1 (fr) 1991-06-23
CZ656790A3 (en) 1996-08-14
JPH04103573A (ja) 1992-04-06
PL164694B1 (pl) 1994-09-30
PT96313B (pt) 1998-06-30
AU628699B2 (en) 1992-09-17
CN1052666A (zh) 1991-07-03
DK0436426T3 (da) 1994-07-04
FR2656302A1 (fr) 1991-06-28
RU1836356C (ru) 1993-08-23
SK278447B6 (en) 1997-06-04
FR2656302B1 (fr) 1992-05-07
EP0436426A1 (fr) 1991-07-10
PL288365A1 (en) 1991-09-09
ATE107289T1 (de) 1994-07-15
FI103203B (fi) 1999-05-14
UA27220C2 (uk) 2000-08-15
FI103203B1 (fi) 1999-05-14
NZ236621A (en) 1992-04-28
FI906366A0 (fi) 1990-12-21
US5166358A (en) 1992-11-24
HU908416D0 (en) 1991-07-29
IE904142A1 (en) 1991-07-03
DE69009964D1 (de) 1994-07-21
IE65510B1 (en) 1995-11-01
ES2055382T3 (es) 1994-08-16
AU6826590A (en) 1991-06-27
ZA909648B (en) 1992-02-26
FI906366A (fi) 1991-06-23
KR0173307B1 (ko) 1999-02-01
DE69009964T2 (de) 1994-10-13
HU207301B (en) 1993-03-29
IL96696A (en) 1995-08-31
JP2836041B2 (ja) 1998-12-14
SK656790A3 (en) 1997-06-04
EP0436426B1 (fr) 1994-06-15
CA2032988C (fr) 2003-04-29

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Legal Events

Date Code Title Description
BB1A Laying open of patent application

Effective date: 19910509

FG3A Patent granted, date of granting

Effective date: 19980330

PC3A Transfer or assignment

Free format text: 19991011 HOECHST MARION ROUSSEL FR

PD3A Change of proprietorship

Owner name: ROUSSEL UCLAF

Effective date: 19991011

TE3A Change of address (patent)

Owner name: ROUSSEL UCLAF

Effective date: 19991011

PC3A Transfer or assignment

Free format text: AVENTIS PHARMA S.A. FR

Effective date: 20030110

MM4A Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: MAXIMUM VALIDITY LIMIT REACHED

Effective date: 20130401