ATE210675T1 - Zwischenprodukten für oligonukleotid-synthese - Google Patents

Zwischenprodukten für oligonukleotid-synthese

Info

Publication number
ATE210675T1
ATE210675T1 AT97924155T AT97924155T ATE210675T1 AT E210675 T1 ATE210675 T1 AT E210675T1 AT 97924155 T AT97924155 T AT 97924155T AT 97924155 T AT97924155 T AT 97924155T AT E210675 T1 ATE210675 T1 AT E210675T1
Authority
AT
Austria
Prior art keywords
group
hydrogen
formula
nucleoside
nuc
Prior art date
Application number
AT97924155T
Other languages
English (en)
Inventor
Stephen Paul Collingwood
Heinz Ernst Moser
Karl-Heinz Altmann
Mark Edward Douglas
Original Assignee
Isis Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Isis Pharmaceuticals Inc filed Critical Isis Pharmaceuticals Inc
Application granted granted Critical
Publication of ATE210675T1 publication Critical patent/ATE210675T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
AT97924155T 1996-06-13 1997-06-03 Zwischenprodukten für oligonukleotid-synthese ATE210675T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9612600.8A GB9612600D0 (en) 1996-06-13 1996-06-13 Chemical compounds
PCT/GB1997/001490 WO1997047636A2 (en) 1996-06-13 1997-06-03 Intermediates for oligonucleotide synthesis

Publications (1)

Publication Number Publication Date
ATE210675T1 true ATE210675T1 (de) 2001-12-15

Family

ID=10795396

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97924155T ATE210675T1 (de) 1996-06-13 1997-06-03 Zwischenprodukten für oligonukleotid-synthese

Country Status (12)

Country Link
US (1) US6329519B1 (de)
EP (1) EP0906327B1 (de)
JP (1) JP2000512288A (de)
CN (1) CN1221423A (de)
AT (1) ATE210675T1 (de)
AU (1) AU2971997A (de)
BR (1) BR9709791A (de)
CA (1) CA2257453A1 (de)
DE (1) DE69709098T2 (de)
GB (1) GB9612600D0 (de)
WO (1) WO1997047636A2 (de)
ZA (1) ZA975197B (de)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6770748B2 (en) 1997-03-07 2004-08-03 Takeshi Imanishi Bicyclonucleoside and oligonucleotide analogue
JP3756313B2 (ja) * 1997-03-07 2006-03-15 武 今西 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体
USRE44779E1 (en) 1997-03-07 2014-02-25 Santaris Pharma A/S Bicyclonucleoside and oligonucleotide analogues
US7030230B2 (en) 2002-10-25 2006-04-18 Isis Pharmaceuticals, Inc. Process of purifying phosphoramidites
EP1692139B1 (de) 2003-11-13 2013-02-13 Isis Pharmaceuticals, Inc. 5,6-dihydroxy-isoindolderivate als linker für die festphasensynthese von oligomeren

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3307744A1 (de) 1983-03-04 1984-09-06 Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig 2'-desoxy-3'-phosphonylmethyl-nucleoside
JPH03503894A (ja) * 1988-03-25 1991-08-29 ユニバーシィティ オブ バージニア アランミ パテンツ ファウンデイション オリゴヌクレオチド n‐アルキルホスホラミデート
US5658731A (en) * 1990-04-09 1997-08-19 Europaisches Laboratorium Fur Molekularbiologie 2'-O-alkylnucleotides as well as polymers which contain such nucleotides
DE4037363A1 (de) 1990-04-09 1991-10-10 Europ Lab Molekularbiolog 2-0-alkylnukleotide sowie polymere, die solche nukleotide enthalten
US5386023A (en) * 1990-07-27 1995-01-31 Isis Pharmaceuticals Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling
US5378825A (en) 1990-07-27 1995-01-03 Isis Pharmaceuticals, Inc. Backbone modified oligonucleotide analogs
GB9304618D0 (en) 1993-03-06 1993-04-21 Ciba Geigy Ag Chemical compounds
GB9311682D0 (en) 1993-06-05 1993-07-21 Ciba Geigy Ag Chemical compounds
GB9417746D0 (en) 1994-09-03 1994-10-19 Ciba Geigy Ag Chemical compounds

Also Published As

Publication number Publication date
JP2000512288A (ja) 2000-09-19
ZA975197B (en) 1997-12-15
AU2971997A (en) 1998-01-07
EP0906327B1 (de) 2001-12-12
GB9612600D0 (en) 1996-08-21
US6329519B1 (en) 2001-12-11
CA2257453A1 (en) 1997-12-18
BR9709791A (pt) 1999-08-10
DE69709098D1 (de) 2002-01-24
DE69709098T2 (de) 2002-09-05
WO1997047636A3 (en) 1998-02-12
CN1221423A (zh) 1999-06-30
EP0906327A2 (de) 1999-04-07
WO1997047636A2 (en) 1997-12-18

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