ATE210675T1 - Zwischenprodukten für oligonukleotid-synthese - Google Patents
Zwischenprodukten für oligonukleotid-syntheseInfo
- Publication number
- ATE210675T1 ATE210675T1 AT97924155T AT97924155T ATE210675T1 AT E210675 T1 ATE210675 T1 AT E210675T1 AT 97924155 T AT97924155 T AT 97924155T AT 97924155 T AT97924155 T AT 97924155T AT E210675 T1 ATE210675 T1 AT E210675T1
- Authority
- AT
- Austria
- Prior art keywords
- group
- hydrogen
- formula
- nucleoside
- nuc
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 238000002515 oligonucleotide synthesis Methods 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 3
- 229910052739 hydrogen Inorganic materials 0.000 abstract 3
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 3
- 125000000008 (C1-C10) alkyl group Chemical group 0.000 abstract 2
- 125000003342 alkenyl group Chemical group 0.000 abstract 2
- 125000003710 aryl alkyl group Chemical group 0.000 abstract 2
- 125000003118 aryl group Chemical group 0.000 abstract 2
- 125000001316 cycloalkyl alkyl group Chemical group 0.000 abstract 2
- 239000002777 nucleoside Substances 0.000 abstract 2
- 150000003833 nucleoside derivatives Chemical class 0.000 abstract 2
- 108091034117 Oligonucleotide Proteins 0.000 abstract 1
- 125000004429 atom Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000623 heterocyclic group Chemical group 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB9612600.8A GB9612600D0 (en) | 1996-06-13 | 1996-06-13 | Chemical compounds |
PCT/GB1997/001490 WO1997047636A2 (en) | 1996-06-13 | 1997-06-03 | Intermediates for oligonucleotide synthesis |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE210675T1 true ATE210675T1 (de) | 2001-12-15 |
Family
ID=10795396
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT97924155T ATE210675T1 (de) | 1996-06-13 | 1997-06-03 | Zwischenprodukten für oligonukleotid-synthese |
Country Status (12)
Country | Link |
---|---|
US (1) | US6329519B1 (de) |
EP (1) | EP0906327B1 (de) |
JP (1) | JP2000512288A (de) |
CN (1) | CN1221423A (de) |
AT (1) | ATE210675T1 (de) |
AU (1) | AU2971997A (de) |
BR (1) | BR9709791A (de) |
CA (1) | CA2257453A1 (de) |
DE (1) | DE69709098T2 (de) |
GB (1) | GB9612600D0 (de) |
WO (1) | WO1997047636A2 (de) |
ZA (1) | ZA975197B (de) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6770748B2 (en) | 1997-03-07 | 2004-08-03 | Takeshi Imanishi | Bicyclonucleoside and oligonucleotide analogue |
JP3756313B2 (ja) * | 1997-03-07 | 2006-03-15 | 武 今西 | 新規ビシクロヌクレオシド及びオリゴヌクレオチド類縁体 |
USRE44779E1 (en) | 1997-03-07 | 2014-02-25 | Santaris Pharma A/S | Bicyclonucleoside and oligonucleotide analogues |
US7030230B2 (en) | 2002-10-25 | 2006-04-18 | Isis Pharmaceuticals, Inc. | Process of purifying phosphoramidites |
EP1692139B1 (de) | 2003-11-13 | 2013-02-13 | Isis Pharmaceuticals, Inc. | 5,6-dihydroxy-isoindolderivate als linker für die festphasensynthese von oligomeren |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3307744A1 (de) | 1983-03-04 | 1984-09-06 | Gesellschaft für Biotechnologische Forschung mbH (GBF), 3300 Braunschweig | 2'-desoxy-3'-phosphonylmethyl-nucleoside |
WO1989009221A1 (en) * | 1988-03-25 | 1989-10-05 | University Of Virginia Alumni Patents Foundation | Oligonucleotide n-alkylphosphoramidates |
DE4037363A1 (de) | 1990-04-09 | 1991-10-10 | Europ Lab Molekularbiolog | 2-0-alkylnukleotide sowie polymere, die solche nukleotide enthalten |
US5658731A (en) * | 1990-04-09 | 1997-08-19 | Europaisches Laboratorium Fur Molekularbiologie | 2'-O-alkylnucleotides as well as polymers which contain such nucleotides |
US5378825A (en) | 1990-07-27 | 1995-01-03 | Isis Pharmaceuticals, Inc. | Backbone modified oligonucleotide analogs |
US5386023A (en) * | 1990-07-27 | 1995-01-31 | Isis Pharmaceuticals | Backbone modified oligonucleotide analogs and preparation thereof through reductive coupling |
GB9304618D0 (en) * | 1993-03-06 | 1993-04-21 | Ciba Geigy Ag | Chemical compounds |
GB9311682D0 (en) | 1993-06-05 | 1993-07-21 | Ciba Geigy Ag | Chemical compounds |
GB9417746D0 (en) * | 1994-09-03 | 1994-10-19 | Ciba Geigy Ag | Chemical compounds |
-
1996
- 1996-06-13 GB GBGB9612600.8A patent/GB9612600D0/en active Pending
-
1997
- 1997-06-03 CN CN97195452A patent/CN1221423A/zh active Pending
- 1997-06-03 US US09/202,294 patent/US6329519B1/en not_active Expired - Lifetime
- 1997-06-03 AU AU29719/97A patent/AU2971997A/en not_active Abandoned
- 1997-06-03 CA CA002257453A patent/CA2257453A1/en not_active Abandoned
- 1997-06-03 EP EP97924155A patent/EP0906327B1/de not_active Expired - Lifetime
- 1997-06-03 BR BR9709791A patent/BR9709791A/pt not_active Application Discontinuation
- 1997-06-03 WO PCT/GB1997/001490 patent/WO1997047636A2/en active IP Right Grant
- 1997-06-03 JP JP10501337A patent/JP2000512288A/ja active Pending
- 1997-06-03 AT AT97924155T patent/ATE210675T1/de active
- 1997-06-03 DE DE69709098T patent/DE69709098T2/de not_active Expired - Lifetime
- 1997-06-12 ZA ZA9705197A patent/ZA975197B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0906327B1 (de) | 2001-12-12 |
ZA975197B (en) | 1997-12-15 |
BR9709791A (pt) | 1999-08-10 |
DE69709098T2 (de) | 2002-09-05 |
AU2971997A (en) | 1998-01-07 |
CN1221423A (zh) | 1999-06-30 |
WO1997047636A2 (en) | 1997-12-18 |
EP0906327A2 (de) | 1999-04-07 |
US6329519B1 (en) | 2001-12-11 |
WO1997047636A3 (en) | 1998-02-12 |
JP2000512288A (ja) | 2000-09-19 |
CA2257453A1 (en) | 1997-12-18 |
DE69709098D1 (de) | 2002-01-24 |
GB9612600D0 (en) | 1996-08-21 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ATE188216T1 (de) | Therapeutische mittel für die parkinsonsche krankheit | |
DK0915866T3 (da) | Forbedret fremgangsmåde til syntese af beskyttende estere af (S)-3,4-dihydroxysmørsyre | |
IL117848A0 (en) | Novel compounds a process for their production and pharmacetical compositions containing same | |
GR3036017T3 (en) | Heterocyclic fungicides | |
MX9204029A (es) | Procedimiento de preparacion de un derivado de la bacatina iii y de la 10-desacetil bacatina iii | |
MX9602806A (es) | Derivados del 1,2,4-oxadiazol y su uso como parasiticidas para animales. | |
HUP0003484A2 (hu) | Pirrolidin-3-karbonsav-származékok és alkalmazásuk endotelin antagonistaként | |
TR199801039T2 (xx) | Yeni fenilamidin t�revlerinin elde edilmesine y�nelik usul. | |
EP1022276A4 (de) | Epoxybernsteinsäureamid-derivate | |
EP0714900A3 (de) | Alkylhydrogenchlorsilane, Verfahren zu deren Herstellung und deren Verwendung | |
ATE143023T1 (de) | Chirale 1,5-diiodo-2-methoxy oder benzyloxy zwischenprodukte | |
TR200001239T2 (tr) | Tiyazolidinediyon türevlerini hazırlama prosesi. | |
ATE210675T1 (de) | Zwischenprodukten für oligonukleotid-synthese | |
ES2055535T3 (es) | Derivados de amina. | |
YU12000A (sh) | Supstituisani 1,2,3,4,5,6-heksahidro-2,6-metano-3-benzazocin -10-oli, postupak za njihovo pripremanje i njihova primena kao lekova | |
ATE234818T1 (de) | Chinolinderivate, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel | |
NO981970L (no) | FremgangsmÕte for fremstilling av Camptothecin-derivater | |
TR200100286T2 (tr) | (1H)-Benzo[C]kuinolizin-3-on türevlerinin sentezi için proses. | |
SE8501988D0 (sv) | Iminothiazolidine derivatives | |
ATE102955T1 (de) | Zyklisches tetrapeptid und verfahren zu dessen herstellung. | |
HUP9900903A2 (hu) | Eljárás 2-aril-benzo[b]tiofén-származékok és intermedierjeik előállítására | |
ATE106080T1 (de) | Sulfonylindolizinderivate, verfahren zu ihrer herstellung und ihre verwendung als synthese- zwischenprodukte. | |
YU71400A (sh) | Poboljšani postupak za pripremanje farmaceutski dragocenih derivata norbenzomorfana | |
DE3860117D1 (de) | 2,3-dihydro-3-phenyl-benzofuran-2-on-acetamidderivate, verfahren zu ihrer herstellung und diese enthaltende arzneimittel. | |
ATE219497T1 (de) | 15-methyl-cyclopropanosteroide und verfharen zu ihrer herstellung |