US5498088A
(en)
*
|
1992-07-27 |
1996-03-12 |
Choate; John I. M. |
Keyboard arrangement to maximize typing speed and ease of transition from a qwerty keyboard
|
US5836705A
(en)
*
|
1992-07-27 |
1998-11-17 |
Choate; John I. M. |
Keyboard arrangement to maximize typing speed and data entry and to ease transition from a qwerty keyboard
|
US5352050A
(en)
*
|
1992-07-27 |
1994-10-04 |
Choate John I M |
Keyboard arrangement to maximize typing speed and ease of transition from a QWERTY keyboard
|
DK72793D0
(da)
*
|
1993-06-21 |
1993-06-21 |
Novo Nordisk As |
Nyt produkt
|
US5461031A
(en)
*
|
1994-06-16 |
1995-10-24 |
Eli Lilly And Company |
Monomeric insulin analog formulations
|
US5474978A
(en)
*
|
1994-06-16 |
1995-12-12 |
Eli Lilly And Company |
Insulin analog formulations
|
US5547929A
(en)
*
|
1994-09-12 |
1996-08-20 |
Eli Lilly And Company |
Insulin analog formulations
|
US5693609A
(en)
*
|
1994-11-17 |
1997-12-02 |
Eli Lilly And Company |
Acylated insulin analogs
|
AR002976A1
(es)
*
|
1995-03-31 |
1998-05-27 |
Lilly Co Eli |
Formulaciones farmaceuticas parenterales de efecto prolongado de insulina; cristales de dichos analogos aplicables en dichas formulaciones yprocedimiento de las formulaciones mencionadas
|
US6274549B1
(en)
*
|
1995-06-30 |
2001-08-14 |
Novo Nordisk A/S |
Treatment of type 1 diabetes
|
WO1997048414A1
(en)
*
|
1996-06-20 |
1997-12-24 |
Novo Nordisk A/S |
INSULIN PREPARATIONS CONTAINING NaCl
|
PE79099A1
(es)
|
1997-06-13 |
1999-08-24 |
Lilly Co Eli |
Formulaciones de insulina estables
|
KR20010024556A
(ko)
|
1997-10-24 |
2001-03-26 |
피터 지. 스트링거 |
불용성 인슐린 조성물
|
US6531448B1
(en)
*
|
1997-12-23 |
2003-03-11 |
Eli Lilly And Company |
Insoluble compositions for controlling blood glucose
|
DE69924232D1
(de)
*
|
1998-01-09 |
2005-04-21 |
Novo Nordisk As |
Stabilisierte insulin-zubereitungen
|
PT1121145E
(pt)
*
|
1998-10-16 |
2002-09-30 |
Novo Nordisk As |
Preparacoes de insulina contendo mentol e destinadas a administracao via pulmonar
|
US6211144B1
(en)
|
1998-10-16 |
2001-04-03 |
Novo Nordisk A/S |
Stable concentrated insulin preparations for pulmonary delivery
|
US6635617B1
(en)
|
1998-10-16 |
2003-10-21 |
Novo Nordisk A/S |
Insulin preparations for pulmonary delivery containing menthol
|
PL197504B1
(pl)
*
|
1998-10-16 |
2008-04-30 |
Novo Nordisk As |
Trwałe stężone preparaty insulinowe do podawania do płuc
|
US6489292B1
(en)
|
1998-11-18 |
2002-12-03 |
Novo Nordisk A/S |
Stable aqueous insulin preparations without phenol and cresol
|
WO2000029013A1
(en)
*
|
1998-11-18 |
2000-05-25 |
Novo Nordisk A/S |
Stable aqueous insulin preparations without phenol and cresol
|
US20040214747A1
(en)
*
|
1999-01-06 |
2004-10-28 |
Dimarchi Richard Dennis |
Method for administering monomeric insulin
|
US7678364B2
(en)
|
1999-08-25 |
2010-03-16 |
Alkermes, Inc. |
Particles for inhalation having sustained release properties
|
US7022674B2
(en)
|
1999-12-16 |
2006-04-04 |
Eli Lilly And Company |
Polypeptide compositions with improved stability
|
AU2001220765A1
(en)
|
2000-01-24 |
2001-07-31 |
Medtronic Minimed, Inc. |
Mixed buffer system for stabilizing polypeptide formulations
|
US20040037828A1
(en)
|
2002-07-09 |
2004-02-26 |
Bar-Ilan University |
Methods and pharmaceutical compositions for healing wounds
|
IL154210A0
(en)
*
|
2000-07-31 |
2003-07-31 |
Univ Bar Ilan |
Methods and pharmaceutical compositions for healing wounds
|
DE10114178A1
(de)
*
|
2001-03-23 |
2002-10-10 |
Aventis Pharma Gmbh |
Zinkfreie und zinkarme Insulinzubereitungen mit verbesserter Stabilität
|
US6737401B2
(en)
|
2001-06-28 |
2004-05-18 |
Metronic Minimed, Inc. |
Methods of evaluating protein formulation stability and surfactant-stabilized insulin formulations derived therefrom
|
AU2003223158B2
(en)
|
2002-01-09 |
2008-01-17 |
Emisphere Technologies, Inc. |
Polymorphs of sodium 4-[(4-chloro-2-hydroxybenzoyl)amino]butanoate
|
US20040005999A1
(en)
*
|
2002-03-07 |
2004-01-08 |
Andreasen Kasper Huus |
Polyamino acid-based particle insulin preparation
|
US20030211976A1
(en)
*
|
2002-03-07 |
2003-11-13 |
Andreasen Kasper Huus |
Polyamino acid-based particle insulin formulation
|
DE10227232A1
(de)
*
|
2002-06-18 |
2004-01-15 |
Aventis Pharma Deutschland Gmbh |
Saure Insulinzubereitungen mit verbesserter Stabilität
|
US20060258561A1
(en)
*
|
2003-03-13 |
2006-11-16 |
Novo Nordisk A/S |
Novel NPH insulin preparations
|
AU2004247762B2
(en)
|
2003-06-17 |
2010-05-27 |
Sembiosys Genetics Inc. |
Methods for the production of insulin in plants
|
ES2328579T3
(es)
*
|
2003-07-25 |
2009-11-16 |
Conjuchem Biotechnologies Inc. |
Derivados de insulina de larga duracion y procedimientos asociados.
|
US7658721B2
(en)
*
|
2004-01-16 |
2010-02-09 |
Biodel Inc. |
Sublingual drug delivery device
|
US20080096800A1
(en)
*
|
2004-03-12 |
2008-04-24 |
Biodel, Inc. |
Rapid mucosal gel or film insulin compositions
|
US20080085298A1
(en)
*
|
2004-03-12 |
2008-04-10 |
Biodel, Inc. |
Rapid Mucosal Gel or Film Insulin Compositions
|
US20080090753A1
(en)
|
2004-03-12 |
2008-04-17 |
Biodel, Inc. |
Rapid Acting Injectable Insulin Compositions
|
ES2879880T3
(es)
|
2004-05-06 |
2021-11-23 |
Novo Nordisk North America Operations As |
Formas polimórficas cristalinas del n-[8-(2-hidroxibenzoil)amino]caprilato monosódico
|
NZ551241A
(en)
*
|
2004-05-14 |
2010-08-27 |
Emisphere Tech Inc |
Aryl ketone compounds and compositions for delivering active agents
|
US20080044481A1
(en)
*
|
2004-05-27 |
2008-02-21 |
Mordechai Harel |
Microparticles for Oral Delivery
|
UA91512C2
(ru)
|
2004-07-19 |
2010-08-10 |
Биокон Лимитед |
Коньюгати олигомеров инсулина, их композиция (варианты) и применение
|
AU2005271526B2
(en)
|
2004-08-03 |
2011-12-08 |
Emisphere Technologies, Inc. |
Antidiabetic oral insulin-biguanide combination
|
US7597884B2
(en)
|
2004-08-09 |
2009-10-06 |
Alios Biopharma, Inc. |
Hyperglycosylated polypeptide variants and methods of use
|
US20060078622A1
(en)
*
|
2004-08-13 |
2006-04-13 |
Emisphere Technologies, Inc. |
Pharmaceutical formulations containing microparticles or nanoparticles of a delivery agent
|
EP3689366A1
(en)
*
|
2004-10-05 |
2020-08-05 |
Novo Nordisk A/S |
A pharmaceutical formulation
|
WO2006053906A1
(en)
|
2004-11-22 |
2006-05-26 |
Novo Nordisk A/S |
Soluble, stable insulin-containing formulations with a protamine salt
|
US7833513B2
(en)
|
2004-12-03 |
2010-11-16 |
Rhode Island Hospital |
Treatment of Alzheimer's Disease
|
JPWO2006093222A1
(ja)
*
|
2005-03-02 |
2008-08-07 |
味の素株式会社 |
インスリンの多量体形成阻害剤
|
CA2625674C
(en)
|
2005-08-29 |
2015-04-14 |
Healor Ltd. |
Methods and compositions for prevention and treatment of diabetic and aged skin
|
CN105641686A
(zh)
*
|
2005-09-19 |
2016-06-08 |
爱密斯菲尔科技公司 |
N-(5-氯水杨酰基)-8-氨基辛酸的二钠盐的晶形
|
US7713929B2
(en)
*
|
2006-04-12 |
2010-05-11 |
Biodel Inc. |
Rapid acting and long acting insulin combination formulations
|
US8084420B2
(en)
|
2005-09-29 |
2011-12-27 |
Biodel Inc. |
Rapid acting and long acting insulin combination formulations
|
JP2009527526A
(ja)
*
|
2006-02-21 |
2009-07-30 |
ノボ・ノルデイスク・エー/エス |
単鎖インスリンのアナログとその製薬的製剤
|
US8927015B2
(en)
|
2006-04-12 |
2015-01-06 |
Emisphere Technologies, Inc. |
Formulations for delivering insulin
|
WO2007121256A2
(en)
|
2006-04-12 |
2007-10-25 |
Biodel, Inc. |
Rapid acting and long acting insulin combination formulations
|
EP2074140B8
(en)
|
2006-10-04 |
2015-10-28 |
Case Western Reserve University |
Fibrillation-resistant insulin and insulin analogues
|
CA2681158C
(en)
|
2007-03-13 |
2018-09-18 |
Nutrition 21, Inc. |
Methods and compositions for the sustained release of chromium
|
JP5526018B2
(ja)
*
|
2007-03-21 |
2014-06-18 |
エミスフェアー・テクノロジーズ・インク |
アリルオキシおよびアルキルオキシ安息香酸送達薬剤
|
EP2152243A2
(en)
*
|
2007-04-30 |
2010-02-17 |
Novo Nordisk A/S |
Highly concentrated insulin solutions and compositions
|
WO2009002867A2
(en)
|
2007-06-26 |
2008-12-31 |
Nutrition 21, Inc. |
Multiple unit dosage form having a therapeutic agents in combination with a nutritional supplement
|
UA114700C2
(uk)
|
2007-10-16 |
2017-07-25 |
Біокон Лімітед |
Тверда фармацевтична форма для перорального застосування та процес її виготовлення
|
NZ585080A
(en)
|
2007-11-02 |
2012-05-25 |
Emisphere Tech Inc |
Composition comprising Vitamin B12 and N-[8-(2-hydroxybenzoyl) amino ]caprylic acid and salts thereof for treating Vitamin B12 deficiency
|
MX2011001181A
(es)
|
2008-07-31 |
2011-04-05 |
Univ Case Western Reserve |
Insulina estabilizada con halogeno.
|
CN102209541B
(zh)
|
2008-09-08 |
2016-05-18 |
小利兰·斯坦福大学托管委员会 |
醛脱氢酶活性调节剂和其使用方法
|
CA3016451A1
(en)
|
2008-10-17 |
2010-04-22 |
Sanofi-Aventis Deutschland Gmbh |
Combination of an insulin and a glp-1 agonist
|
CN102202669A
(zh)
|
2008-10-28 |
2011-09-28 |
利兰·斯坦福青年大学托管委员会 |
醛脱氢酶调节剂及其使用方法
|
US8940690B2
(en)
|
2009-01-28 |
2015-01-27 |
National Institutes Of Health (Nih) |
Synthetic conjugates and uses thereof
|
MA33064B1
(fr)
|
2009-01-28 |
2012-02-01 |
Smartcells Inc |
Systemes à base de conjugués pour administration contrôlée de médicaments
|
BRPI1008415A2
(pt)
|
2009-02-12 |
2018-02-27 |
Proyecto De Biomedicina Cima S.L. |
uso de cardiotrofina-1 para o tratamento de doenças metabólicas
|
US9060927B2
(en)
|
2009-03-03 |
2015-06-23 |
Biodel Inc. |
Insulin formulations for rapid uptake
|
WO2010107519A1
(en)
|
2009-03-20 |
2010-09-23 |
Smartcells, Inc. |
Terminally-functionalized conjugates and uses thereof
|
KR101772372B1
(ko)
|
2009-11-13 |
2017-08-29 |
사노피-아벤티스 도이칠란트 게엠베하 |
Glp-1 효능제 및 메티오닌을 포함하는 약제학적 조성물
|
RU2537239C2
(ru)
|
2009-11-13 |
2014-12-27 |
Санофи-Авентис Дойчланд Гмбх |
Фармацевтическая композиция, включающая агонист glp-1, инсулин и метионин
|
CN102724994A
(zh)
|
2010-01-11 |
2012-10-10 |
希尔洛有限公司 |
用于治疗炎性疾病和病症的方法
|
NZ701274A
(en)
*
|
2010-02-24 |
2016-03-31 |
Emisphere Tech Inc |
Oral b12 therapy
|
HUE031181T2
(en)
|
2010-08-30 |
2017-06-28 |
Sanofi Aventis Deutschland |
Use of AVE0010 for the manufacture of a medicament for the treatment of type 2 diabetes
|
CN103261181A
(zh)
|
2010-09-30 |
2013-08-21 |
索尔维公司 |
天然来源的环氧氯丙烷的衍生物
|
WO2012115641A1
(en)
|
2011-02-23 |
2012-08-30 |
Elona Biotechnologies |
Lis-pro proinsulin compositions and methods of producing lis-pro insulin analogs therefrom
|
WO2012119007A1
(en)
|
2011-03-01 |
2012-09-07 |
N21 Acquisition Holding, Llc |
Compositions of insulin and chromium for the treatment and prevention of diabetes, hypoglycemia and related disorders
|
US10457659B2
(en)
|
2011-04-29 |
2019-10-29 |
The Board Of Trustees Of The Leland Stanford Junior University |
Compositions and methods for increasing proliferation of adult salivary stem cells
|
US9821032B2
(en)
|
2011-05-13 |
2017-11-21 |
Sanofi-Aventis Deutschland Gmbh |
Pharmaceutical combination for improving glycemic control as add-on therapy to basal insulin
|
SI2750699T1
(sl)
|
2011-08-29 |
2015-11-30 |
Sanofi-Aventis Deutschland Gmbh |
Farmacevtska kombinacija, za uporabo pri glikemični kontroli pri pacientih, ki imajo sladkorno bolezen tipa 2
|
TWI559929B
(en)
|
2011-09-01 |
2016-12-01 |
Sanofi Aventis Deutschland |
Pharmaceutical composition for use in the treatment of a neurodegenerative disease
|
WO2013063572A1
(en)
|
2011-10-27 |
2013-05-02 |
Case Western Reserve University |
Ultra-concentrated rapid-acting insulin analogue formulations
|
US10159735B2
(en)
*
|
2012-06-26 |
2018-12-25 |
The Curators Of The University Of Missouri |
Photocleavable drug conjugates
|
EP2877200B1
(en)
|
2012-07-17 |
2019-05-08 |
Case Western Reserve University |
O-linked carbohydrate-modified insulin analogues
|
KR20150082640A
(ko)
|
2012-11-13 |
2015-07-15 |
아도시아 |
치환된 음이온성 화합물을 포함하는 속효성 인슐린 제형
|
US9707276B2
(en)
|
2012-12-03 |
2017-07-18 |
Merck Sharp & Dohme Corp. |
O-glycosylated carboxy terminal portion (CTP) peptide-based insulin and insulin analogues
|
BR112015011179A8
(pt)
|
2012-12-19 |
2019-10-01 |
Wockhardt Ltd |
composições farmacêuticas aquosas estáveis compreendendo insulina humana ou um análogo ou derivado das mesmas, seu uso e processos para sua preparação
|
RU2015130613A
(ru)
|
2012-12-26 |
2017-01-31 |
Вокхардт Лимитед |
Фармацевтическая композиция
|
KR20150135332A
(ko)
|
2013-03-14 |
2015-12-02 |
더 보드 오브 트러스티스 오브 더 리랜드 스탠포드 쥬니어 유니버시티 |
미토콘드리아 알데히드 탈수소효소-2 조절인자들 및 이들의 사용 방법
|
AR098168A1
(es)
|
2013-10-25 |
2016-05-04 |
Sanofi Sa |
Formulación estable de insulina glulisina
|
WO2016032869A1
(en)
|
2014-08-26 |
2016-03-03 |
Merck Sharp & Dohme Corp. |
Method for preparing crystalline insulin or insulin analog compositions
|
HRP20230470T1
(hr)
|
2014-12-12 |
2023-07-21 |
Sanofi-Aventis Deutschland Gmbh |
Formulacija fiksnog omjera inzulin glargin/liksisenatid
|
AR102869A1
(es)
|
2014-12-16 |
2017-03-29 |
Lilly Co Eli |
Composiciones de insulina de rápida acción
|
TWI748945B
(zh)
|
2015-03-13 |
2021-12-11 |
德商賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患治療
|
TW201705975A
(zh)
|
2015-03-18 |
2017-02-16 |
賽諾菲阿凡提斯德意志有限公司 |
第2型糖尿病病患之治療
|
JO3749B1
(ar)
|
2015-08-27 |
2021-01-31 |
Lilly Co Eli |
تركيبات إنسولين سريعة المفعول
|
EP3413900A1
(en)
|
2016-02-11 |
2018-12-19 |
Nutrition 21, LLC |
Chromium containing compositions for improving health and fitness
|
ES2912162T3
(es)
|
2017-06-01 |
2022-05-24 |
Lilly Co Eli |
Composiciones de insulina de acción rápida
|
EP3727424A4
(en)
|
2017-12-18 |
2021-10-27 |
Merck Sharp & Dohme Corp. |
CONJUGATE-BASED SYSTEMS FOR CONTROLLED INSULIN RELEASE
|
US11413352B2
(en)
|
2017-12-18 |
2022-08-16 |
Merck, Sharp & Dohme LLC |
Conjugate based systems for controlled insulin delivery
|
US11951186B2
(en)
|
2019-10-25 |
2024-04-09 |
Willow Laboratories, Inc. |
Indicator compounds, devices comprising indicator compounds, and methods of making and using the same
|
AU2021247169A1
(en)
|
2020-03-31 |
2022-10-20 |
Protomer Technologies Inc. |
Conjugates for selective responsiveness to vicinal diols
|
EP4247429A1
(en)
|
2020-11-19 |
2023-09-27 |
Protomer Technologies Inc. |
Aromatic boron-containing compounds and insulin analogs
|
TW202409070A
(zh)
|
2022-05-18 |
2024-03-01 |
美商普羅托莫科技公司 |
芳族含硼化合物及相關胰島素類似物
|