SI9012429B - Novi derivati kromana in tiokromana - Google Patents

Novi derivati kromana in tiokromana Download PDF

Info

Publication number
SI9012429B
SI9012429B SI9012429A SI9012429A SI9012429B SI 9012429 B SI9012429 B SI 9012429B SI 9012429 A SI9012429 A SI 9012429A SI 9012429 A SI9012429 A SI 9012429A SI 9012429 B SI9012429 B SI 9012429B
Authority
SI
Slovenia
Prior art keywords
alkyl
formula
alkenyl
compound
hydrogen
Prior art date
Application number
SI9012429A
Other languages
English (en)
Slovenian (sl)
Other versions
SI9012429A (en
Inventor
Lars-Gunnar Larsson
Rolf Noreen
Lucy Anna Renyi
Svante Bertil Ross
Daniel Dungan Sohn
Bjoern Eric Svensson
Seth Olov Thorberg
Original Assignee
Aktiebolaget Astra
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aktiebolaget Astra filed Critical Aktiebolaget Astra
Publication of SI9012429A publication Critical patent/SI9012429A/sl
Publication of SI9012429B publication Critical patent/SI9012429B/sl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D335/00Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/04Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D335/06Benzothiopyrans; Hydrogenated benzothiopyrans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D407/00Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/04Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D413/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pyrane Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Cosmetics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Threshing Machine Elements (AREA)
  • Bakery Products And Manufacturing Methods Therefor (AREA)
  • Liquid Crystal Substances (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Emulsifying, Dispersing, Foam-Producing Or Wetting Agents (AREA)
  • Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
  • Harvester Elements (AREA)
  • Medicinal Preparation (AREA)
  • Curing Cements, Concrete, And Artificial Stone (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
SI9012429A 1989-12-22 1990-12-21 Novi derivati kromana in tiokromana SI9012429B (sl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE8904361A SE8904361D0 (sv) 1989-12-22 1989-12-22 New chroman and thiochroman derivatives
YU242990A YU47936B (sh) 1989-12-22 1990-12-21 Derivati hromana i tiohromana i postupak za njihovo dobijanje

Publications (2)

Publication Number Publication Date
SI9012429A SI9012429A (en) 1997-12-31
SI9012429B true SI9012429B (sl) 1998-10-31

Family

ID=20377869

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9012429A SI9012429B (sl) 1989-12-22 1990-12-21 Novi derivati kromana in tiokromana

Country Status (42)

Country Link
EP (1) EP0460169B1 (esLanguage)
JP (1) JP2879972B2 (esLanguage)
KR (1) KR0178991B1 (esLanguage)
CN (1) CN1037438C (esLanguage)
AT (1) ATE138918T1 (esLanguage)
AU (1) AU641204B2 (esLanguage)
CA (1) CA2047237C (esLanguage)
CY (1) CY1991A (esLanguage)
CZ (1) CZ283630B6 (esLanguage)
DE (1) DE69027311T2 (esLanguage)
DK (1) DK0460169T3 (esLanguage)
DZ (1) DZ1469A1 (esLanguage)
EG (1) EG19749A (esLanguage)
ES (1) ES2087993T3 (esLanguage)
FI (1) FI102177B (esLanguage)
GR (1) GR3020497T3 (esLanguage)
HK (1) HK55897A (esLanguage)
HR (1) HRP920851B1 (esLanguage)
HU (1) HU211860A9 (esLanguage)
ID (1) ID945B (esLanguage)
IE (1) IE80753B1 (esLanguage)
IL (1) IL96712A (esLanguage)
IS (1) IS1665B (esLanguage)
LT (1) LT3967B (esLanguage)
LV (2) LV10449B (esLanguage)
MX (1) MX23889A (esLanguage)
NO (1) NO180336C (esLanguage)
NZ (1) NZ236407A (esLanguage)
PH (1) PH30797A (esLanguage)
PL (3) PL164592B1 (esLanguage)
PT (1) PT96304B (esLanguage)
RU (1) RU2092483C1 (esLanguage)
SA (1) SA90110186B1 (esLanguage)
SE (1) SE8904361D0 (esLanguage)
SG (1) SG48043A1 (esLanguage)
SI (1) SI9012429B (esLanguage)
SK (1) SK657890A3 (esLanguage)
TW (1) TW221056B (esLanguage)
UA (1) UA34416C2 (esLanguage)
WO (1) WO1991009853A1 (esLanguage)
YU (2) YU47936B (esLanguage)
ZA (1) ZA909708B (esLanguage)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5420151A (en) * 1989-12-22 1995-05-30 Aktiebolaget Astra Chroman derivatives
ATE149480T1 (de) * 1990-08-15 1997-03-15 Lilly Co Eli Ring-substituierte 2-amino-1,2,3,4-tetra- hydronaphthaline, 3-aminochromane und 3- aminothiochromane
EP0498590B1 (en) * 1991-02-08 1997-04-09 Eli Lilly And Company Ring-substituted 2-amino-1,2,3,4-tetra-hydronaphthalenes
HRP920935A2 (en) * 1991-10-08 1995-08-31 Astra Ab New therapeutically active compound
SE9103745D0 (sv) * 1991-12-18 1991-12-18 Wikstroem Haakan Aryl-triflates and related compounds
FR2691149B1 (fr) * 1992-05-18 1994-07-08 Adir Nouveaux composes thiochromaniques, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent.
US5434174A (en) * 1992-07-17 1995-07-18 Eli Lilly And Company Isoxazole derivatives for the treatment of irritable bowel syndrome
SE9301732D0 (sv) * 1993-05-18 1993-05-18 Haakan Wilhelm Wikstroem New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
SE9703377D0 (sv) 1997-09-18 1997-09-18 Astra Ab New compounds
SE9703378D0 (sv) 1997-09-18 1997-09-18 Astra Ab New compounds
TW555757B (en) * 1998-07-31 2003-10-01 Akzo Nobel Nv Aminomethylcarboxylic acid derivatives
US6184226B1 (en) 1998-08-28 2001-02-06 Scios Inc. Quinazoline derivatives as inhibitors of P-38 α
WO2002055014A2 (en) * 2001-01-16 2002-07-18 Astrazeneca Ab Therapeutic chroman compounds
CN100509794C (zh) 2001-01-16 2009-07-08 阿斯特拉曾尼卡有限公司 治疗性杂环化合物
CA2433950A1 (en) 2001-01-16 2002-07-18 Timothy Davenport Therapeutic chromone compounds
RU2193559C1 (ru) * 2001-05-16 2002-11-27 Пермская государственная фармацевтическая академия 2,4-ксилидид и м-фенетидид 2-ацетилиминокумарин-3-карбоновой кислоты, обладающие антикоагулянтной активностью
EP1408976B3 (en) 2001-07-20 2010-08-25 Psychogenics Inc. Treatment for attention-deficit hyperactivity disorder
US7125904B2 (en) 2002-10-11 2006-10-24 Portela & C.A., S.A. Peripherally-selective inhibitors of dopamine-β-hydroxylase and method of their preparation
SE0301796D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use II
SE0301795D0 (sv) * 2003-06-19 2003-06-19 Astrazeneca Ab New use I
US20080221193A1 (en) * 2006-12-22 2008-09-11 Wyeth 3-amino chromane derivatives
SA08290245B1 (ar) * 2007-04-23 2012-02-12 استرازينيكا ايه بي مشتقات كربو كساميد جديدة من -n (8-اريل رباعي هيدرو نفثالين غير متجانس- 2- يل) أو -n (5-اريل كرومان غير متجانس -3-يل) لعلاج الألم
CN101712672B (zh) * 2008-10-06 2013-02-06 中国中医科学院中药研究所 一种治疗心脑血管系统疾病新化合物及其制备方法、用途
DE102010041948A1 (de) 2010-10-04 2012-04-05 Mahle International Gmbh Filtereinrichtung
GB201316410D0 (en) 2013-09-13 2013-10-30 Bial Portela & Ca Sa Processes for preparing peripherally-selective inhibitors of dopamine-?-hydroxylase and intermediates for use therein
CN116655242A (zh) * 2023-05-10 2023-08-29 东北大学 一系列有机-无机杂化金属卤化物玻璃材料及其制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH22522A (en) * 1985-09-03 1988-10-17 Ciba Geigy Ag 3-amino-dihydro-1-benzopyrans and benzothiopyrans, their pharmaceutical compositions and method of using said compounds
US4801605A (en) * 1986-08-29 1989-01-31 Ciba-Geigy Corporation 3-amino-dihydro-[1]-benzopyrans and benzothiopyrans
SE8605504D0 (sv) * 1986-12-19 1986-12-19 Astra Laekemedel Ab Novel chroman derivatives
US5258287A (en) * 1988-03-22 1993-11-02 Genentech, Inc. DNA encoding and methods of production of insulin-like growth factor binding protein BP53

Also Published As

Publication number Publication date
EG19749A (en) 1996-01-31
IL96712A0 (en) 1991-09-16
EP0460169A1 (en) 1991-12-11
FI102177B1 (fi) 1998-10-30
LT3967B (en) 1996-05-27
PL164609B1 (en) 1994-08-31
PL164592B1 (pl) 1994-08-31
PT96304B (pt) 1998-09-30
PL293066A1 (en) 1992-08-10
LTIP1730A (en) 1995-08-25
MX23889A (es) 1993-10-01
CA2047237C (en) 2003-02-11
LV11894A (lv) 1997-12-20
ES2087993T3 (es) 1996-08-01
NO180336B (no) 1996-12-23
IL96712A (en) 1995-08-31
DE69027311T2 (de) 1996-10-24
PH30797A (en) 1997-10-17
CZ283630B6 (cs) 1998-05-13
CZ657890A3 (cs) 1998-02-18
KR920701193A (ko) 1992-08-11
GR3020497T3 (en) 1996-10-31
LV10449A (lv) 1995-02-20
IE904535A1 (en) 1991-07-03
SK280261B6 (sk) 1999-10-08
ZA909708B (en) 1991-08-28
HU211860A9 (en) 1995-12-28
RU2092483C1 (ru) 1997-10-10
LV11894B (en) 1998-05-20
PL164608B1 (pl) 1994-08-31
YU47936B (sh) 1996-05-20
HRP920851B1 (en) 2000-02-29
PT96304A (pt) 1991-09-30
WO1991009853A1 (en) 1991-07-11
DZ1469A1 (fr) 2004-09-13
HK55897A (en) 1997-05-09
FI102177B (fi) 1998-10-30
IS1665B (is) 1997-07-04
PL293065A1 (en) 1992-08-10
AU641204B2 (en) 1993-09-16
HRP920851A2 (en) 1995-10-31
IS3662A7 (is) 1991-06-23
YU242990A (sh) 1993-10-20
TW221056B (esLanguage) 1994-02-11
ID945B (id) 1996-09-20
DK0460169T3 (da) 1996-09-23
CN1052669A (zh) 1991-07-03
SA90110186B1 (ar) 2001-11-11
SI9012429A (en) 1997-12-31
LV10449B (en) 1995-10-20
EP0460169B1 (en) 1996-06-05
SK657890A3 (en) 1999-10-08
ATE138918T1 (de) 1996-06-15
CN1037438C (zh) 1998-02-18
NZ236407A (en) 1993-08-26
CY1991A (en) 1997-09-05
JPH04503682A (ja) 1992-07-02
NO913273L (no) 1991-10-08
DE69027311D1 (en) 1996-07-11
KR0178991B1 (ko) 1999-03-20
NO913273D0 (no) 1991-08-21
SG48043A1 (en) 1998-04-17
NO180336C (no) 1997-04-02
YU47923B (sh) 1996-05-20
FI913943A0 (fi) 1991-08-21
CA2047237A1 (en) 1991-06-23
JP2879972B2 (ja) 1999-04-05
IE80753B1 (en) 1999-01-13
SE8904361D0 (sv) 1989-12-22
UA34416C2 (uk) 2001-03-15
AU6977091A (en) 1991-07-24
YU72191A (sh) 1995-01-31

Similar Documents

Publication Publication Date Title
SI9012429B (sl) Novi derivati kromana in tiokromana
DE69513383D1 (de) Substituierte 3-arylidinene-7-azaoxindol verbindungen und verfahren zu ihrer herstellung
TWI245764B (en) Amyloid plaque aggregation inhibitors and diagnostic imaging agents
Occhiato et al. Preparation and Suzuki− Miyaura coupling reactions of tetrahydropyridine-2-boronic acid pinacol esters
ES2559764T3 (es) Complejos de tecnecio-dipiridina, y métodos de uso de los mismos
KR940007026A (ko) 4차 염기성 아미드류, 그의 제조방법 및 그를 함유하는 약학 조성물
Li et al. Selective α‐Oxyamination and Hydroxylation of Aliphatic Amides
ME00376B (me) DIHIDROPTERIDINONI, POSTUPAK ZA NJlHOVO PRIPREMANJE I NJlHOVA PRIMJENA KAO LIJEK
Sisti et al. Intramolecular Diels− Alder Reaction of 2-Cyano-1-aza-1, 3-butadienes
JP2007510668A (ja) キノリノン化合物を合成する方法
González-Temprano et al. Enantiodivergent Synthesis of pyrrolo [2, 1-a] isoquinolines based on diastereoselective Parham cyclization and α-amidoalkylation reactions
Garduno et al. Synthesis of amidines and benzoxazoles from activated nitriles with Ni (0) catalysts
Kim et al. Boron–Heck Reaction of Cyclic Enaminones: Regioselective Direct Arylation via Oxidative Palladium (II) Catalysis
NZ518637A (en) Bicyclic imidazo-3-yl amine derivatives substituted on the 6-membered ring
Hansen et al. Mechanistic evidence for intermolecular radical carbonyl additions promoted by samarium diiodide
Vara et al. Trans-stereoselectivity in the reaction between homophthalic anhydride and imines
Ollero et al. A Kulinkovich entry into tertiary N-acyliminium ion chemistry
SI9111975B (en) Novel derivatives of 3,4-dihydroisoquinoline, processes for their preparation and pharmaceutical compositions containing novel compounds
US8067648B2 (en) Method for synthesizing radioactive ligand having 18F-labeled fluorobenzene ring
Chen et al. Bis (pyridiniopropionate) hydrogen bromide
AU2522692A (en) Imidazol-1-yl methyl pyridine derivatives, processes for their production and their use as pharmaceuticals
Chaudhuri et al. Synthesis of 2, 3-disubstituted pyrroles initiated by 1, 4-addition of chelated enolates onto alkynyl carbene complexes
IS4204A (is) Hliðstæð aðferð við að framleiða ný fenýletýl- ogfenýlprópýlamín
Archibald et al. 1, 4-Bis (2-indol-3-ylethyl) piperazines
PT69804A (de) Neue imidazo/1,2-a/imidazole deren saureadditionssalze diese enthaltende arzneimittel und verfahren zu deren herstellung

Legal Events

Date Code Title Description
IF Valid on the event date
KO00 Lapse of patent

Effective date: 20070821