SI3464318T1 - Agonist glukokortikoidnega receptorja in njegovi imunokonjugati - Google Patents
Agonist glukokortikoidnega receptorja in njegovi imunokonjugatiInfo
- Publication number
- SI3464318T1 SI3464318T1 SI201730791T SI201730791T SI3464318T1 SI 3464318 T1 SI3464318 T1 SI 3464318T1 SI 201730791 T SI201730791 T SI 201730791T SI 201730791 T SI201730791 T SI 201730791T SI 3464318 T1 SI3464318 T1 SI 3464318T1
- Authority
- SI
- Slovenia
- Prior art keywords
- immunoconjugates
- receptor agonist
- glucocorticoid receptor
- glucocorticoid
- agonist
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/241—Tumor Necrosis Factors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
- A61K47/6803—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6845—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a cytokine, e.g. growth factors, VEGF, TNF, a lymphokine or an interferon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6835—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site
- A61K47/6849—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment the modifying agent being an antibody or an immunoglobulin bearing at least one antigen-binding site the antibody targeting a receptor, a cell surface antigen or a cell surface determinant
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
- A61K47/6889—Conjugates wherein the antibody being the modifying agent and wherein the linker, binder or spacer confers particular properties to the conjugates, e.g. peptidic enzyme-labile linkers or acid-labile linkers, providing for an acid-labile immuno conjugate wherein the drug may be released from its antibody conjugated part in an acidic, e.g. tumoural or environment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/0026—Oxygen-containing hetero ring cyclic ketals
- C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/31—Immunoglobulins specific features characterized by aspects of specificity or valency multispecific
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/55—Fab or Fab'
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2318/00—Antibody mimetics or scaffolds
- C07K2318/20—Antigen-binding scaffold molecules wherein the scaffold is not an immunoglobulin variable region or antibody mimetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201662344948P | 2016-06-02 | 2016-06-02 | |
US201662371134P | 2016-08-04 | 2016-08-04 | |
PCT/US2017/035518 WO2017210471A1 (en) | 2016-06-02 | 2017-06-01 | Glucocorticoid receptor agonist and immunoconjugates thereof |
EP17733222.8A EP3464318B1 (en) | 2016-06-02 | 2017-06-01 | Glucocorticoid receptor agonist and immunoconjugates thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
SI3464318T1 true SI3464318T1 (sl) | 2021-07-30 |
Family
ID=59215995
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI201730791T SI3464318T1 (sl) | 2016-06-02 | 2017-06-01 | Agonist glukokortikoidnega receptorja in njegovi imunokonjugati |
Country Status (35)
Country | Link |
---|---|
US (4) | US20180126000A1 (sl) |
EP (2) | EP3901162A1 (sl) |
JP (2) | JP6843891B2 (sl) |
KR (2) | KR102435599B1 (sl) |
CN (1) | CN109476699B (sl) |
AU (2) | AU2017274442B2 (sl) |
BR (1) | BR112018074922B1 (sl) |
CA (1) | CA3025377A1 (sl) |
CL (1) | CL2018003406A1 (sl) |
CO (1) | CO2018012996A2 (sl) |
CR (1) | CR20180594A (sl) |
CY (1) | CY1124293T1 (sl) |
DK (1) | DK3464318T3 (sl) |
DO (1) | DOP2018000261A (sl) |
EC (1) | ECSP18094857A (sl) |
ES (1) | ES2877548T3 (sl) |
HR (1) | HRP20210924T1 (sl) |
HU (1) | HUE054804T2 (sl) |
IL (1) | IL263214B2 (sl) |
LT (1) | LT3464318T (sl) |
MA (1) | MA51586A (sl) |
MX (2) | MX2018014927A (sl) |
MY (1) | MY194619A (sl) |
PE (1) | PE20190622A1 (sl) |
PH (1) | PH12018502539A1 (sl) |
PL (1) | PL3464318T3 (sl) |
PT (1) | PT3464318T (sl) |
RS (1) | RS62040B1 (sl) |
RU (1) | RU2745748C2 (sl) |
SG (2) | SG10202001787QA (sl) |
SI (1) | SI3464318T1 (sl) |
TW (1) | TWI728118B (sl) |
UY (1) | UY37269A (sl) |
WO (1) | WO2017210471A1 (sl) |
ZA (1) | ZA201808623B (sl) |
Families Citing this family (30)
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CR20180594A (es) * | 2016-06-02 | 2019-07-29 | Abbvie Inc | Agonista del receptor de glucocorticoides e inmunoconjugados del mismo |
IL266353B2 (en) | 2016-11-08 | 2024-03-01 | Regeneron Pharma | Steroids and their protein conjugates |
US11491237B2 (en) | 2017-05-18 | 2022-11-08 | Regeneron Pharmaceuticals, Inc. | Cyclodextrin protein drug conjugates |
RU2020117698A (ru) | 2017-12-01 | 2022-01-04 | Эббви Инк. | Агонист глюкокортикоидного рецептора и его иммуноконъюгаты |
MX2020006994A (es) * | 2018-01-08 | 2020-11-06 | Regeneron Pharma | Esteroides y conjugados de anticuerpos de los mismos. |
CN110357959B (zh) * | 2018-04-10 | 2023-02-28 | 鸿运华宁(杭州)生物医药有限公司 | Gcgr抗体及其与glp-1的融合蛋白质,以及其药物组合物和应用 |
CA3098453A1 (en) | 2018-05-09 | 2019-11-14 | Regeneron Pharmaceuticals, Inc. | Anti-msr1 antibodies and methods of use thereof |
MX2021008114A (es) * | 2019-01-08 | 2021-08-05 | Regeneron Pharma | Enlazadores sin rastro y conjugados de proteinas de los mismos. |
US20220389092A1 (en) * | 2019-04-05 | 2022-12-08 | The Regents Of The University Of California | Methods and compositions involving chimeric binding polypeptides |
WO2021161263A1 (en) * | 2020-02-13 | 2021-08-19 | Abbvie Inc. | Glucocorticoid receptor agonist and immunoconjugates thereof |
WO2022135332A1 (zh) * | 2020-12-21 | 2022-06-30 | 映恩生物制药(苏州)有限公司 | 一种甾体偶联物 |
CA3203533A1 (en) * | 2021-01-07 | 2022-07-14 | Jay ROTHSTEIN | Novel steroid payloads, steroid linkers, adcs containing and use thereof |
JP2024506012A (ja) * | 2021-02-04 | 2024-02-08 | 上海森▲輝▼医▲葯▼有限公司 | グルココルチコイド受容体アゴニストの薬物複合体及びその医薬的応用 |
WO2022171101A1 (zh) * | 2021-02-10 | 2022-08-18 | 映恩生物制药(苏州)有限公司 | 一种甾体偶联物 |
AR125084A1 (es) | 2021-03-23 | 2023-06-07 | Lilly Co Eli | Agonistas del receptor de glucocorticoides novedosos |
AR125079A1 (es) | 2021-03-23 | 2023-06-07 | Lilly Co Eli | Agonistas de receptores de glucocorticoides sustituidos con carboxi |
TW202304462A (zh) | 2021-03-23 | 2023-02-01 | 美商美國禮來大藥廠 | 糖皮質素受體激動劑 |
WO2022268176A1 (zh) * | 2021-06-24 | 2022-12-29 | 江苏先声药业有限公司 | 甾体类化合物、其药物组合物及其应用 |
US20230183331A1 (en) * | 2021-07-09 | 2023-06-15 | Bright Peak Therapeutics Ag | Modified tnf-alpha antibodies and uses thereof |
WO2023025248A1 (zh) * | 2021-08-26 | 2023-03-02 | 映恩生物制药(苏州)有限公司 | 一种甾体化合物及其缀合物 |
TW202327620A (zh) * | 2021-09-14 | 2023-07-16 | 大陸商映恩生物製藥(蘇州)有限公司 | 一種抗炎症的化合物及其用途 |
WO2023092048A1 (en) | 2021-11-18 | 2023-05-25 | Adafre Biosciences, Llc | Anti-tnf-alpha antibodies and compositions |
TW202340252A (zh) * | 2022-01-29 | 2023-10-16 | 大陸商上海盛迪醫藥有限公司 | 糖皮質激素的藥物偶聯物 |
TW202345788A (zh) * | 2022-04-01 | 2023-12-01 | 大陸商江蘇先聲藥業有限公司 | 配體-藥物偶聯物及其用途 |
WO2023220549A1 (en) | 2022-05-13 | 2023-11-16 | Eli Lilly And Company | Human tumor necrosis factor alpha antibody glucocorticoid conjugates |
WO2023235738A1 (en) | 2022-06-02 | 2023-12-07 | Eli Lilly And Company | Human interleukin-4 receptor alpha antibody glucocorticoid conjugates |
WO2023250341A2 (en) | 2022-06-22 | 2023-12-28 | Eli Lilly And Company | Human cd33 antibodies and glucocorticoid conjugates |
WO2024006681A1 (en) | 2022-06-28 | 2024-01-04 | Adafre Biosciences, Llc | Anti-tnf-αlpha antibodies and compositions |
WO2024020164A2 (en) | 2022-07-21 | 2024-01-25 | Firefly Bio, Inc. | Glucocorticoid receptor agonists and conjugates thereof |
WO2024064779A1 (en) | 2022-09-22 | 2024-03-28 | Eli Lilly And Company | Glucocorticoid receptor agonists |
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- 2018-11-29 CL CL2018003406A patent/CL2018003406A1/es unknown
- 2018-11-30 MX MX2020012562A patent/MX2020012562A/es unknown
- 2018-11-30 CO CONC2018/0012996A patent/CO2018012996A2/es unknown
- 2018-11-30 DO DO2018000261A patent/DOP2018000261A/es unknown
- 2018-12-20 ZA ZA2018/08623A patent/ZA201808623B/en unknown
- 2018-12-26 EC ECSENADI201894857A patent/ECSP18094857A/es unknown
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2019
- 2019-05-10 US US16/408,602 patent/US10668167B2/en active Active
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2020
- 2020-04-16 US US16/850,866 patent/US20200338208A1/en not_active Abandoned
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2021
- 2021-02-22 JP JP2021025922A patent/JP2021088582A/ja active Pending
- 2021-05-12 US US17/318,723 patent/US20220354959A1/en active Pending
- 2021-06-09 HR HRP20210924TT patent/HRP20210924T1/hr unknown
- 2021-06-28 CY CY20211100570T patent/CY1124293T1/el unknown
- 2021-11-19 AU AU2021269433A patent/AU2021269433A1/en not_active Abandoned
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