SI1196410T1 - Respiratory syncytial virus replication inhibitors - Google Patents
Respiratory syncytial virus replication inhibitorsInfo
- Publication number
- SI1196410T1 SI1196410T1 SI200030358T SI200030358T SI1196410T1 SI 1196410 T1 SI1196410 T1 SI 1196410T1 SI 200030358 T SI200030358 T SI 200030358T SI 200030358 T SI200030358 T SI 200030358T SI 1196410 T1 SI1196410 T1 SI 1196410T1
- Authority
- SI
- Slovenia
- Prior art keywords
- respiratory syncytial
- syncytial virus
- virus replication
- replication inhibitors
- inhibitors
- Prior art date
Links
- 241000725643 Respiratory syncytial virus Species 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
- 230000029812 viral genome replication Effects 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP99202089 | 1999-06-28 | ||
| PCT/EP2000/005677 WO2001000615A1 (en) | 1999-06-28 | 2000-06-20 | Respiratory syncytial virus replication inhibitors |
| EP00936899A EP1196410B1 (de) | 1999-06-28 | 2000-06-20 | Respiratorisches syncytialvirus replikation inhibitoren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SI1196410T1 true SI1196410T1 (en) | 2004-08-31 |
Family
ID=8240374
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI200030358T SI1196410T1 (en) | 1999-06-28 | 2000-06-20 | Respiratory syncytial virus replication inhibitors |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US7071192B1 (de) |
| EP (2) | EP1400519B1 (de) |
| JP (1) | JP2003503403A (de) |
| KR (1) | KR100731273B1 (de) |
| CN (1) | CN1171887C (de) |
| AR (1) | AR024495A1 (de) |
| AT (2) | ATE356121T1 (de) |
| AU (1) | AU774829B2 (de) |
| BG (1) | BG65373B1 (de) |
| BR (1) | BR0011997A (de) |
| CA (1) | CA2376785A1 (de) |
| CZ (1) | CZ20014573A3 (de) |
| DE (2) | DE60008382T2 (de) |
| DK (1) | DK1196410T3 (de) |
| EA (1) | EA004746B1 (de) |
| EE (1) | EE04592B1 (de) |
| ES (2) | ES2215670T3 (de) |
| HK (1) | HK1045998B (de) |
| HR (2) | HRP20010934A2 (de) |
| HU (1) | HUP0201789A3 (de) |
| IL (2) | IL147328A0 (de) |
| MX (1) | MXPA02000117A (de) |
| MY (1) | MY129810A (de) |
| NO (1) | NO321599B1 (de) |
| NZ (1) | NZ515392A (de) |
| PL (1) | PL200694B1 (de) |
| PT (1) | PT1196410E (de) |
| SI (1) | SI1196410T1 (de) |
| SK (1) | SK18952001A3 (de) |
| TR (2) | TR200500707T2 (de) |
| TW (1) | TWI267513B (de) |
| UA (1) | UA75866C2 (de) |
| WO (1) | WO2001000615A1 (de) |
| ZA (1) | ZA200110473B (de) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6495580B1 (en) | 1998-01-29 | 2002-12-17 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| CA2336909C (en) | 1998-07-15 | 2009-10-20 | Teijin Limited | Thiobenzimidazole derivatives which are useful as inhibitors of human chymase activity |
| US20040010004A1 (en) | 2000-01-17 | 2004-01-15 | Naoki Tsuchiya | Benzimidazole derivatives |
| CA2396908A1 (en) * | 2000-01-17 | 2001-07-26 | Teijin Limited | Benzimidazole derivative |
| US6489338B2 (en) | 2000-06-13 | 2002-12-03 | Bristol-Myers Squibb Company | Imidazopyridine and imidazopyrimidine antiviral agents |
| US6506738B1 (en) | 2000-09-27 | 2003-01-14 | Bristol-Myers Squibb Company | Benzimidazolone antiviral agents |
| ES2243579T3 (es) | 2000-12-15 | 2005-12-01 | Glaxo Group Ltd | Derivados de pirazolopirideno. |
| ATE301653T1 (de) | 2000-12-15 | 2005-08-15 | Glaxo Group Ltd | Pyrazolopyridine |
| US6774134B2 (en) | 2000-12-20 | 2004-08-10 | Bristol-Myers Squibb Company | Heterocyclic substituted 2-methyl-benzimidazole antiviral agents |
| WO2002072581A2 (en) | 2001-03-08 | 2002-09-19 | Smithkline Beecham Corporation | Pyrazolopyriadine derivatives |
| JP4237497B2 (ja) | 2001-03-30 | 2009-03-11 | スミスクライン ビーチャム コーポレーション | ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用 |
| US7141569B2 (en) | 2001-04-10 | 2006-11-28 | Smithkline Beecham Corporation | Antiviral pyrazolopyridine compounds |
| JP2004527560A (ja) | 2001-04-27 | 2004-09-09 | スミスクライン ビーチャム コーポレーション | ピラゾロ［１，５−α］ピリジン誘導体 |
| US7030150B2 (en) | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
| BR0210464A (pt) | 2001-06-21 | 2004-07-20 | Smithkline Beecham Corp | Composto, composição farmacêutica, processo para preparar um composto, e, uso de um composto |
| EP1432712B1 (de) * | 2001-10-05 | 2006-05-17 | SmithKline Beecham Corporation | Imidazopyridinderivate zur verwendung bei der behandlung von herpes-vireninfektion |
| US6919331B2 (en) | 2001-12-10 | 2005-07-19 | Bristol-Myers Squibb Company | Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents |
| ES2292839T3 (es) | 2001-12-11 | 2008-03-16 | Smithkline Beecham Corporation | Derivados de pirazolo-piridina como agentes contra el herpes. |
| US7244847B2 (en) * | 2002-02-06 | 2007-07-17 | Isis Pharmaceuticals, Inc. | Benzimidazole compounds |
| AU2003258177A1 (en) | 2002-08-09 | 2004-02-25 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| WO2004014316A2 (en) | 2002-08-09 | 2004-02-19 | Viropharma Incorporated | Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases |
| AU2003275266A1 (en) | 2002-10-03 | 2004-05-04 | Smithkline Beecham Corporation | Therapeutic compounds based on pyrazolopyridine derivatives |
| WO2005042530A1 (en) | 2003-10-30 | 2005-05-12 | Boehringer Ingelheim (Canada) Ltd. | Rsv polymerase inhibitors |
| SI1697347T1 (sl) * | 2003-12-18 | 2011-06-30 | Tibotec Pharm Ltd | 5- ali 6-substituirani benzimidazolni derivati kot inhibitorji replikacije respiratornega sincicijskega virusa |
| AR046959A1 (es) * | 2003-12-18 | 2006-01-04 | Tibotec Pharm Ltd | Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio |
| AU2004298458B2 (en) * | 2003-12-18 | 2010-05-20 | Tibotec Pharmaceuticals Ltd. | Amino-benzimidazoles derivatives as inhibitors of respiratory syncytial virus replication |
| TWI378926B (en) * | 2003-12-18 | 2012-12-11 | Tibotec Pharm Ltd | Amino-benzimidazoles derivatives as inhibitors of respiratory syncytial virus replication |
| CN103450159A (zh) * | 2003-12-18 | 2013-12-18 | 泰博特克药品有限公司 | 作为呼吸道合胞病毒复制的抑制剂的哌啶-氨基-苯并咪唑类衍生物 |
| AU2004298457B2 (en) * | 2003-12-18 | 2010-05-27 | Tibotec Pharmaceuticals Ltd. | Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication |
| BRPI0606278B8 (pt) | 2005-03-17 | 2021-05-25 | Janssen R & D Ireland | aminas de 1,3-diidro-benzimidazol-2-ilideno como inibidores de replicação de vírus sincicial respiratório, seu processo de preparação e composição farmacêutica |
| JP5078887B2 (ja) * | 2005-06-20 | 2012-11-21 | テイボテク・フアーマシユーチカルズ | 呼吸器シンシチウムウイルスに活性をもつ、１−（２−アミノ−３−（置換アルキル）−３ｈ−ベンズイミダゾイルメチル）−３−置換−１，３−ジヒドロ−ベンゾイミダゾル−２−オン |
| EP1896449B1 (de) | 2005-06-20 | 2013-11-06 | Janssen R&D Ireland | Heterocyclylaminoalkylsubstituierte benzimidazole |
| CL2008001003A1 (es) | 2007-04-11 | 2008-10-17 | Actelion Pharmaceuticals Ltd | Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana. |
| US20110190336A1 (en) * | 2008-10-16 | 2011-08-04 | Cara Therapeutics, Inc. | Azabenzimidazolones |
| JP5487692B2 (ja) | 2009-04-10 | 2014-05-07 | 国立大学法人京都大学 | 複素環骨格を有する化合物および該化合物を不斉触媒として用いる光学活性化合物の製造方法 |
| WO2011002635A1 (en) * | 2009-06-30 | 2011-01-06 | Siga Technologies, Inc. | Treatment and prevention of dengue virus infections |
| US8993604B2 (en) | 2009-06-30 | 2015-03-31 | Siga Technologies, Inc. | Treatment and prevention of dengue virus infections |
| EP2733141B1 (de) * | 2011-07-15 | 2019-01-09 | Shionogi & Co., Ltd. | Azabenzimidazolderivate mit ampk-aktivierender wirkung |
| CA2882088C (en) * | 2012-08-23 | 2021-11-23 | Alios Biopharma, Inc. | Compounds for the treatment of paramoxyvirus viral infections |
| JP2016079168A (ja) | 2014-10-17 | 2016-05-16 | 塩野義製薬株式会社 | ９員縮合環誘導体 |
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| CA1140119A (en) | 1978-04-03 | 1983-01-25 | Joseph Torremans | N-heterocyclyl-4-piperidinamines |
| US4556660A (en) | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| US4634704A (en) | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
| US4695569A (en) | 1983-11-30 | 1987-09-22 | Janssen Pharmaceutica N.V. | Bicyclic heterocyclyl containing N-(bicyclic heterocyclyl)-4-piperidinamines |
| DE3484096D1 (de) | 1983-11-30 | 1991-03-14 | Janssen Pharmaceutica Nv | Bizyklisches heterozyklyl aufveisende n-(bizyklisches heterozyklyl-4-piperidinamine. |
| US4588722A (en) | 1984-01-09 | 1986-05-13 | Janssen Pharmaceutica N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives |
| PH23995A (en) | 1984-01-09 | 1990-02-09 | Janssen Pharmaceutica Nv | 4((bicycle heterocyclyl)-methyl and hetero)piperidines |
| EP0232937B1 (de) | 1986-02-03 | 1992-08-19 | Janssen Pharmaceutica N.V. | N-Heterozyklische-4-piperidinamine enthaltende anti-histaminische Zusammensetzungen |
| US4897401A (en) | 1987-06-19 | 1990-01-30 | Janssen Pharmaceutical N.V. | N-(4-piperidinyl) bicyclic condensed 2-imidazolamine derivatives useful in treating allergic diseases |
| CA1317939C (en) * | 1987-07-01 | 1993-05-18 | Janssen Pharmaceutica Naamloze Vennootschap | ¬(bicyclic heterocyclyl)methyl and -hetero| substituted hexahydro-1h-azepines and pyrrolidines |
| GB8716313D0 (en) | 1987-07-10 | 1987-08-19 | Janssen Pharmaceutica Nv | 2-(heterocyclylalkyl)imidazopyridines |
| US5597824A (en) | 1987-11-03 | 1997-01-28 | Abbott Laboratories | Analogs of oxetanyl purines and pyrimidines |
| IE904378A1 (en) | 1989-12-20 | 1991-07-03 | Abbott Lab | Analogs of oxetanyl purines and pyrimidines |
| KR100190299B1 (ko) | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
| NZ238863A (en) * | 1990-07-19 | 1993-03-26 | Janssen Pharmaceutica Nv | Substituted thiazolyl and pyridinyl derivatives |
| US5567824A (en) * | 1994-05-24 | 1996-10-22 | Merck & Co., Inc. | Palladium catalyzed ring closure of triazolyltryptamine |
| US5693661A (en) * | 1995-06-07 | 1997-12-02 | Eli Lilly And Company | Anti-viral compounds |
| PE107598A1 (es) * | 1996-09-11 | 1999-01-29 | Ucb Sa | Cetirizina util para el tratamiento de enfermedades de tipo virico |
| AU6031898A (en) * | 1997-01-22 | 1998-08-07 | Eli Lilly And Company | Anti-viral compounds |
| JP2002503253A (ja) * | 1997-06-04 | 2002-01-29 | イーライ・リリー・アンド・カンパニー | 抗ウイルス化合物 |
| IL138228A0 (en) | 1998-03-06 | 2001-10-31 | Janssen Pharmaceutica Nv | Glycine transport inhibitors |
| JP2002521334A (ja) * | 1998-07-20 | 2002-07-16 | ブリストルーマイヤーズ スクイブ カンパニー | 置換ベンズイミダゾール抗ウィルス剤 |
-
2000
- 2000-06-20 PL PL352385A patent/PL200694B1/pl not_active IP Right Cessation
- 2000-06-20 US US10/019,376 patent/US7071192B1/en not_active Expired - Fee Related
- 2000-06-20 AU AU52222/00A patent/AU774829B2/en not_active Ceased
- 2000-06-20 DE DE60008382T patent/DE60008382T2/de not_active Expired - Fee Related
- 2000-06-20 DK DK00936899T patent/DK1196410T3/da active
- 2000-06-20 CZ CZ20014573A patent/CZ20014573A3/cs unknown
- 2000-06-20 TR TR2005/00707T patent/TR200500707T2/xx unknown
- 2000-06-20 EE EEP200100694A patent/EE04592B1/xx not_active IP Right Cessation
- 2000-06-20 PT PT00936899T patent/PT1196410E/pt unknown
- 2000-06-20 EA EA200200086A patent/EA004746B1/ru not_active IP Right Cessation
- 2000-06-20 EP EP03102464A patent/EP1400519B1/de not_active Expired - Lifetime
- 2000-06-20 JP JP2001507023A patent/JP2003503403A/ja not_active Withdrawn
- 2000-06-20 KR KR1020017015284A patent/KR100731273B1/ko not_active IP Right Cessation
- 2000-06-20 ES ES00936899T patent/ES2215670T3/es not_active Expired - Lifetime
- 2000-06-20 SK SK1895-2001A patent/SK18952001A3/sk unknown
- 2000-06-20 ES ES03102464T patent/ES2283716T3/es not_active Expired - Lifetime
- 2000-06-20 CA CA002376785A patent/CA2376785A1/en not_active Abandoned
- 2000-06-20 IL IL14732800A patent/IL147328A0/xx active IP Right Grant
- 2000-06-20 BR BR0011997-0A patent/BR0011997A/pt not_active Application Discontinuation
- 2000-06-20 UA UA2002010361A patent/UA75866C2/uk unknown
- 2000-06-20 DE DE60033859T patent/DE60033859T2/de not_active Expired - Fee Related
- 2000-06-20 AT AT03102464T patent/ATE356121T1/de not_active IP Right Cessation
- 2000-06-20 EP EP00936899A patent/EP1196410B1/de not_active Expired - Lifetime
- 2000-06-20 HU HU0201789A patent/HUP0201789A3/hu unknown
- 2000-06-20 MX MXPA02000117A patent/MXPA02000117A/es active IP Right Grant
- 2000-06-20 NZ NZ515392A patent/NZ515392A/xx unknown
- 2000-06-20 WO PCT/EP2000/005677 patent/WO2001000615A1/en active Application Filing
- 2000-06-20 CN CNB008095302A patent/CN1171887C/zh not_active Expired - Fee Related
- 2000-06-20 SI SI200030358T patent/SI1196410T1/xx unknown
- 2000-06-20 TR TR2001/03805T patent/TR200103805T2/xx unknown
- 2000-06-20 AT AT00936899T patent/ATE259796T1/de not_active IP Right Cessation
- 2000-06-26 TW TW089112479A patent/TWI267513B/zh not_active IP Right Cessation
- 2000-06-27 AR ARP000103222A patent/AR024495A1/es unknown
- 2000-06-27 MY MYPI20002914A patent/MY129810A/en unknown
-
2001
- 2001-12-19 HR HR20010934A patent/HRP20010934A2/hr not_active Application Discontinuation
- 2001-12-20 ZA ZA200110473A patent/ZA200110473B/xx unknown
- 2001-12-26 IL IL147328A patent/IL147328A/en not_active IP Right Cessation
- 2001-12-27 NO NO20016370A patent/NO321599B1/no unknown
-
2002
- 2002-01-08 BG BG106288A patent/BG65373B1/bg unknown
- 2002-10-21 HK HK02107623.8A patent/HK1045998B/zh not_active IP Right Cessation
-
2005
- 2005-10-11 US US11/247,392 patent/US7407969B2/en not_active Expired - Fee Related
-
2008
- 2008-08-12 HR HR20080390A patent/HRP20080390A2/xx not_active Application Discontinuation
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