SI1697347T1 - 5- ali 6-substituirani benzimidazolni derivati kot inhibitorji replikacije respiratornega sincicijskega virusa - Google Patents
5- ali 6-substituirani benzimidazolni derivati kot inhibitorji replikacije respiratornega sincicijskega virusaInfo
- Publication number
- SI1697347T1 SI1697347T1 SI200431657T SI200431657T SI1697347T1 SI 1697347 T1 SI1697347 T1 SI 1697347T1 SI 200431657 T SI200431657 T SI 200431657T SI 200431657 T SI200431657 T SI 200431657T SI 1697347 T1 SI1697347 T1 SI 1697347T1
- Authority
- SI
- Slovenia
- Prior art keywords
- inhibitors
- respiratory syncytial
- syncytial virus
- virus replication
- benzimidazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03104806 | 2003-12-18 | ||
US56686704P | 2004-04-30 | 2004-04-30 | |
EP04804954A EP1697347B1 (en) | 2003-12-18 | 2004-12-20 | 5- or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication |
PCT/EP2004/053618 WO2005058874A1 (en) | 2003-12-18 | 2004-12-20 | 5- or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication |
Publications (1)
Publication Number | Publication Date |
---|---|
SI1697347T1 true SI1697347T1 (sl) | 2011-06-30 |
Family
ID=43646156
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200431657T SI1697347T1 (sl) | 2003-12-18 | 2004-12-20 | 5- ali 6-substituirani benzimidazolni derivati kot inhibitorji replikacije respiratornega sincicijskega virusa |
Country Status (19)
Country | Link |
---|---|
US (2) | US20070093502A1 (sl) |
EP (1) | EP1697347B1 (sl) |
JP (1) | JP2007514719A (sl) |
KR (1) | KR101123055B1 (sl) |
CN (1) | CN1914196B (sl) |
AR (1) | AR046770A1 (sl) |
AT (1) | ATE499361T1 (sl) |
AU (1) | AU2004298459B2 (sl) |
BR (1) | BRPI0417273A (sl) |
CA (1) | CA2548793A1 (sl) |
DE (1) | DE602004031555D1 (sl) |
DK (1) | DK1697347T3 (sl) |
HR (1) | HRP20110313T1 (sl) |
MX (1) | MXPA06007111A (sl) |
MY (1) | MY142783A (sl) |
RU (1) | RU2369606C2 (sl) |
SI (1) | SI1697347T1 (sl) |
TW (1) | TWI382981B (sl) |
WO (1) | WO2005058874A1 (sl) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BRPI0611744B8 (pt) * | 2005-06-20 | 2021-05-25 | Janssen R & D Ireland | benzimidazóis heterociclilaminoalquila substituída, seu processo de preparação e composição farmacêutica |
TWI650321B (zh) | 2011-10-14 | 2019-02-11 | 美商安比特生物科學公司 | 雜環化合物及其使用方法 |
TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
MX2018014032A (es) | 2017-03-20 | 2019-08-21 | Forma Therapeutics Inc | Composiciones de pirrolopirrol como activadores de piruvato cinasa (pkr). |
US10793551B2 (en) | 2017-10-19 | 2020-10-06 | Effector Therapeutics Inc. | Benzimidazole-indole inhibitors of Mnk1 and Mnk2 |
CN113226356A (zh) | 2018-09-19 | 2021-08-06 | 福马治疗股份有限公司 | 活化丙酮酸激酶r |
EP3853206B1 (en) | 2018-09-19 | 2024-04-10 | Novo Nordisk Health Care AG | Treating sickle cell disease with a pyruvate kinase r activating compound |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4025621A (en) * | 1975-01-09 | 1977-05-24 | Purdy Clarence L | Method of curing and providing immunity from viral infections |
CA1140119A (en) | 1978-04-03 | 1983-01-25 | Joseph Torremans | N-heterocyclyl-4-piperidinamines |
US4556660A (en) | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
US4634704A (en) | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
KR100190299B1 (ko) | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
ATE258928T1 (de) * | 1999-06-28 | 2004-02-15 | Janssen Pharmaceutica Nv | Respiratorisches syncytialvirus replikation inhibitoren |
AP1552A (en) * | 1999-06-28 | 2006-01-17 | Janssen Pharmaceutica Nv | Respiratory syncytial virus replication inhibitors. |
DE60033859T2 (de) * | 1999-06-28 | 2007-11-08 | Janssen Pharmaceutica N.V. | Hemmer des Respiratorischen Syncytial Virus |
JP2004532856A (ja) * | 2001-04-30 | 2004-10-28 | 藤沢薬品工業株式会社 | アポリポタンパク質b阻害剤としてのビアリールカルボキサミド化合物 |
US7030150B2 (en) * | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
FR2833948B1 (fr) * | 2001-12-21 | 2004-02-06 | Sod Conseils Rech Applic | Nouveaux derives de benzimidazole et leur utilisation en tant que medicament |
-
2004
- 2004-12-20 AT AT04804954T patent/ATE499361T1/de not_active IP Right Cessation
- 2004-12-20 WO PCT/EP2004/053618 patent/WO2005058874A1/en active Application Filing
- 2004-12-20 MX MXPA06007111A patent/MXPA06007111A/es active IP Right Grant
- 2004-12-20 DE DE602004031555T patent/DE602004031555D1/de active Active
- 2004-12-20 AR ARP040104808A patent/AR046770A1/es not_active Application Discontinuation
- 2004-12-20 EP EP04804954A patent/EP1697347B1/en active Active
- 2004-12-20 BR BRPI0417273-6A patent/BRPI0417273A/pt not_active Application Discontinuation
- 2004-12-20 AU AU2004298459A patent/AU2004298459B2/en not_active Ceased
- 2004-12-20 MY MYPI20045258A patent/MY142783A/en unknown
- 2004-12-20 US US10/596,521 patent/US20070093502A1/en not_active Abandoned
- 2004-12-20 SI SI200431657T patent/SI1697347T1/sl unknown
- 2004-12-20 JP JP2006544465A patent/JP2007514719A/ja active Pending
- 2004-12-20 DK DK04804954.8T patent/DK1697347T3/da active
- 2004-12-20 CA CA002548793A patent/CA2548793A1/en not_active Abandoned
- 2004-12-20 KR KR1020067014248A patent/KR101123055B1/ko not_active IP Right Cessation
- 2004-12-20 CN CN2004800416543A patent/CN1914196B/zh active Active
- 2004-12-20 RU RU2006125727/04A patent/RU2369606C2/ru not_active IP Right Cessation
- 2004-12-20 TW TW093139735A patent/TWI382981B/zh not_active IP Right Cessation
-
2008
- 2008-10-17 US US12/253,450 patent/US8278455B2/en active Active
-
2011
- 2011-04-29 HR HR20110313T patent/HRP20110313T1/hr unknown
Also Published As
Publication number | Publication date |
---|---|
MXPA06007111A (es) | 2006-08-23 |
HRP20110313T1 (hr) | 2011-05-31 |
JP2007514719A (ja) | 2007-06-07 |
TWI382981B (zh) | 2013-01-21 |
CN1914196A (zh) | 2007-02-14 |
DE602004031555D1 (de) | 2011-04-07 |
CN1914196B (zh) | 2012-01-25 |
US8278455B2 (en) | 2012-10-02 |
US20070093502A1 (en) | 2007-04-26 |
DK1697347T3 (da) | 2011-06-06 |
KR101123055B1 (ko) | 2012-04-12 |
RU2006125727A (ru) | 2008-01-27 |
EP1697347B1 (en) | 2011-02-23 |
AU2004298459B2 (en) | 2011-03-17 |
AU2004298459A1 (en) | 2005-06-30 |
TW200531970A (en) | 2005-10-01 |
CA2548793A1 (en) | 2005-06-30 |
EP1697347A1 (en) | 2006-09-06 |
RU2369606C2 (ru) | 2009-10-10 |
WO2005058874A1 (en) | 2005-06-30 |
MY142783A (en) | 2010-12-31 |
ATE499361T1 (de) | 2011-03-15 |
KR20060127047A (ko) | 2006-12-11 |
AR046770A1 (es) | 2005-12-21 |
BRPI0417273A (pt) | 2007-03-27 |
US20090062278A1 (en) | 2009-03-05 |
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