ATE258928T1 - Respiratorisches syncytialvirus replikation inhibitoren - Google Patents

Respiratorisches syncytialvirus replikation inhibitoren

Info

Publication number
ATE258928T1
ATE258928T1 AT00943840T AT00943840T ATE258928T1 AT E258928 T1 ATE258928 T1 AT E258928T1 AT 00943840 T AT00943840 T AT 00943840T AT 00943840 T AT00943840 T AT 00943840T AT E258928 T1 ATE258928 T1 AT E258928T1
Authority
AT
Austria
Prior art keywords
replication inhibitors
syncytialvirus
respiratory
respiratory syncytialvirus
replication
Prior art date
Application number
AT00943840T
Other languages
English (en)
Inventor
Frans Eduard Janssens
Kathleen Petrus Marie Meersman
Francois Maria Sommen
Koenraad Jozef Lodewij Andries
Turnhoutseweg
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Application granted granted Critical
Publication of ATE258928T1 publication Critical patent/ATE258928T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00Technologies relating to chemical industry
    • Y02P20/50Improvements relating to the production of bulk chemicals
    • Y02P20/55Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • Molecular Biology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
AT00943840T 1999-06-28 2000-06-20 Respiratorisches syncytialvirus replikation inhibitoren ATE258928T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202088 1999-06-28
PCT/EP2000/005675 WO2001000612A2 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors

Publications (1)

Publication Number Publication Date
ATE258928T1 true ATE258928T1 (de) 2004-02-15

Family

ID=8240373

Family Applications (1)

Application Number Title Priority Date Filing Date
AT00943840T ATE258928T1 (de) 1999-06-28 2000-06-20 Respiratorisches syncytialvirus replikation inhibitoren

Country Status (33)

Country Link
US (3) US6747028B1 (de)
EP (1) EP1196409B1 (de)
JP (1) JP2003503402A (de)
KR (1) KR100731271B1 (de)
CN (1) CN1210275C (de)
AR (1) AR035991A1 (de)
AT (1) ATE258928T1 (de)
AU (1) AU778218B2 (de)
BG (1) BG65328B1 (de)
BR (1) BR0012047A (de)
CA (1) CA2376676C (de)
DE (1) DE60008112T2 (de)
DK (1) DK1196409T3 (de)
EA (1) EA005027B1 (de)
EE (1) EE04591B1 (de)
ES (1) ES2215683T3 (de)
HK (1) HK1045997A1 (de)
HR (1) HRP20010935A2 (de)
HU (1) HUP0201869A3 (de)
IL (2) IL147327A0 (de)
MX (1) MXPA02000120A (de)
MY (1) MY127687A (de)
NO (1) NO322458B1 (de)
NZ (1) NZ515664A (de)
PL (1) PL200674B1 (de)
PT (1) PT1196409E (de)
SI (1) SI1196409T1 (de)
SK (1) SK19122001A3 (de)
TR (1) TR200103806T2 (de)
TW (1) TWI278454B (de)
UA (1) UA74787C2 (de)
WO (1) WO2001000612A2 (de)
ZA (1) ZA200110479B (de)

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CA2495266A1 (en) 2002-08-09 2004-02-19 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
CA2495245A1 (en) 2002-08-09 2004-02-19 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
US7582761B2 (en) * 2002-10-17 2009-09-01 Amgen Inc. Vanilloid receptor ligands and their use in treatments
JP4537407B2 (ja) 2003-10-30 2010-09-01 ベーリンガー インゲルハイム (カナダ) リミテッド Rsvポリメラーゼインヒビター
PL1711485T3 (pl) 2003-12-18 2009-11-30 Tibotec Pharm Ltd Pochodne aminobenzoimidazoli jako inhibitory replikacji wirusa zespólni układu oddechowego
DK1723136T3 (da) * 2003-12-18 2011-06-27 Tibotec Pharm Ltd Piperidinamino-benzimidazol-derivat som inhibitorer af replikation af respiratorisk syncytial virus
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
ATE435222T1 (de) * 2003-12-18 2009-07-15 Tibotec Pharm Ltd Aminobenzimidazole und benzimidazole als inhibitoren der replikation von respiratory syncytial virus
CN1894236B (zh) * 2003-12-18 2011-08-17 泰博特克药品有限公司 作为呼吸道合胞病毒复制抑制剂的氨基-苯并咪唑类衍生物
AR046770A1 (es) * 2003-12-18 2005-12-21 Tibotec Pharm Ltd Derivados bencimidazol 5- o 6-substituidos como inhibidores de la replicacion del virus sincitial respiratorio
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TWI515187B (zh) 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI527814B (zh) 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
TWI530495B (zh) 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
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ES2790358T3 (es) 2011-12-28 2020-10-27 Global Blood Therapeutics Inc Compuestos de heteroaril aldehído sustituido y métodos para su uso en el aumento de la oxigenación tisular
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US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
EP2968299B1 (de) 2013-03-15 2021-01-20 Global Blood Therapeutics, Inc. Verbindungen und verwendungen davon zur modulation von hämoglobin
EP3919056B1 (de) 2013-03-15 2024-08-28 Global Blood Therapeutics, Inc. Verbindungen und verwendungen davon zur modulation von hämoglobin
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Also Published As

Publication number Publication date
DK1196409T3 (da) 2004-06-07
SK19122001A3 (sk) 2003-01-09
EA005027B1 (ru) 2004-10-28
HUP0201869A3 (en) 2003-12-29
NO20016369L (no) 2002-02-20
HK1045997A1 (zh) 2002-12-20
AU5816600A (en) 2001-01-31
JP2003503402A (ja) 2003-01-28
IL147327A0 (en) 2002-08-14
BR0012047A (pt) 2002-03-12
DE60008112D1 (en) 2004-03-11
DE60008112T2 (de) 2004-09-16
BG65328B1 (bg) 2008-02-29
ES2215683T3 (es) 2004-10-16
KR20020003884A (ko) 2002-01-15
TR200103806T2 (tr) 2002-06-21
KR100731271B1 (ko) 2007-06-21
BG106286A (en) 2002-10-31
MXPA02000120A (es) 2002-07-02
EP1196409A2 (de) 2002-04-17
IL147327A (en) 2007-06-03
US20070135404A1 (en) 2007-06-14
HRP20010935A2 (en) 2003-06-30
CN1210275C (zh) 2005-07-13
EE200100688A (et) 2003-04-15
US7528149B2 (en) 2009-05-05
TWI278454B (en) 2007-04-11
EE04591B1 (et) 2006-02-15
NO322458B1 (no) 2006-10-09
WO2001000612A3 (en) 2001-03-29
UA74787C2 (en) 2006-02-15
ZA200110479B (en) 2003-03-20
EA200200088A1 (ru) 2002-06-27
MY127687A (en) 2006-12-29
AU778218B2 (en) 2004-11-25
PL352378A1 (en) 2003-08-25
NO20016369D0 (no) 2001-12-27
AR035991A1 (es) 2004-08-04
US6747028B1 (en) 2004-06-08
CA2376676C (en) 2009-01-20
SI1196409T1 (en) 2004-06-30
HUP0201869A2 (hu) 2002-11-28
PT1196409E (pt) 2004-06-30
PL200674B1 (pl) 2009-01-30
CA2376676A1 (en) 2001-01-04
US7179811B2 (en) 2007-02-20
US20070015747A1 (en) 2007-01-18
WO2001000612A2 (en) 2001-01-04
NZ515664A (en) 2004-01-30
CN1358181A (zh) 2002-07-10
EP1196409B1 (de) 2004-02-04

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