NO20016369D0 - Respiratorisk syncytialvirus-replikasjonsinhibitorer - Google Patents

Respiratorisk syncytialvirus-replikasjonsinhibitorer

Info

Publication number
NO20016369D0
NO20016369D0 NO20016369A NO20016369A NO20016369D0 NO 20016369 D0 NO20016369 D0 NO 20016369D0 NO 20016369 A NO20016369 A NO 20016369A NO 20016369 A NO20016369 A NO 20016369A NO 20016369 D0 NO20016369 D0 NO 20016369D0
Authority
NO
Norway
Prior art keywords
respiratory syncytial
syncytial virus
virus replication
replication inhibitors
inhibitors
Prior art date
Application number
NO20016369A
Other languages
English (en)
Other versions
NO20016369L (no
NO322458B1 (no
Inventor
Frans Eduard Janssens
Kathleen Petrus Meersman
Francois Maria Sommen
Koenraad Jozef Lodewij Andries
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of NO20016369D0 publication Critical patent/NO20016369D0/no
Publication of NO20016369L publication Critical patent/NO20016369L/no
Publication of NO322458B1 publication Critical patent/NO322458B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
NO20016369A 1999-06-28 2001-12-27 Benzimidazoler og imidazopyridiner, deres fremstilling og sammensetninger omfattende dem, samt deres anvendelse NO322458B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP99202088 1999-06-28
PCT/EP2000/005675 WO2001000612A2 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors

Publications (3)

Publication Number Publication Date
NO20016369D0 true NO20016369D0 (no) 2001-12-27
NO20016369L NO20016369L (no) 2002-02-20
NO322458B1 NO322458B1 (no) 2006-10-09

Family

ID=8240373

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20016369A NO322458B1 (no) 1999-06-28 2001-12-27 Benzimidazoler og imidazopyridiner, deres fremstilling og sammensetninger omfattende dem, samt deres anvendelse

Country Status (33)

Country Link
US (3) US6747028B1 (no)
EP (1) EP1196409B1 (no)
JP (1) JP2003503402A (no)
KR (1) KR100731271B1 (no)
CN (1) CN1210275C (no)
AR (1) AR035991A1 (no)
AT (1) ATE258928T1 (no)
AU (1) AU778218B2 (no)
BG (1) BG65328B1 (no)
BR (1) BR0012047A (no)
CA (1) CA2376676C (no)
DE (1) DE60008112T2 (no)
DK (1) DK1196409T3 (no)
EA (1) EA005027B1 (no)
EE (1) EE04591B1 (no)
ES (1) ES2215683T3 (no)
HK (1) HK1045997A1 (no)
HR (1) HRP20010935A2 (no)
HU (1) HUP0201869A3 (no)
IL (2) IL147327A0 (no)
MX (1) MXPA02000120A (no)
MY (1) MY127687A (no)
NO (1) NO322458B1 (no)
NZ (1) NZ515664A (no)
PL (1) PL200674B1 (no)
PT (1) PT1196409E (no)
SI (1) SI1196409T1 (no)
SK (1) SK19122001A3 (no)
TR (1) TR200103806T2 (no)
TW (1) TWI278454B (no)
UA (1) UA74787C2 (no)
WO (1) WO2001000612A2 (no)
ZA (1) ZA200110479B (no)

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US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
US6919331B2 (en) 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
WO2004014317A2 (en) 2002-08-09 2004-02-19 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
US8202896B2 (en) 2002-08-09 2012-06-19 Microdose Therapeutx, Inc. Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
EP1551811A1 (en) * 2002-10-17 2005-07-13 Amgen Inc. Benzimidazole derivatives and their use as vanilloid receptor ligands
US7323567B2 (en) 2003-10-30 2008-01-29 Boehringer Ingelheim (Canada) Ltd. RSV polymerase inhibitors
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
ATE435222T1 (de) * 2003-12-18 2009-07-15 Tibotec Pharm Ltd Aminobenzimidazole und benzimidazole als inhibitoren der replikation von respiratory syncytial virus
CN1894236B (zh) * 2003-12-18 2011-08-17 泰博特克药品有限公司 作为呼吸道合胞病毒复制抑制剂的氨基-苯并咪唑类衍生物
ATE499361T1 (de) * 2003-12-18 2011-03-15 Tibotec Pharm Ltd 5- oder 6-substituierte benzimidazolderivate als inhibitoren der replikation des respiratory syncytial virus
AR046771A1 (es) 2003-12-18 2005-12-21 Tibotec Pharm Ltd Derivados piperidina-amino-bencimidazol como inhibidores de la replicacion del virus sincitial respiratorio
WO2005058870A1 (en) 2003-12-18 2005-06-30 Tibotec Pharmaceuticals Ltd. Amino-benzimidazoles derivatives as inhibitors of respiratory syncytial virus replication
DE102004010207A1 (de) * 2004-03-02 2005-09-15 Aventis Pharma S.A. Neue 4-Benzimidazol-2-yl-pyridazin-3-on-Derivate
JP5289934B2 (ja) 2005-03-17 2013-09-11 テイボテク・フアーマシユーチカルズ 呼吸シンシチウムウイルス複製の阻害剤としての１，３−ジヒドロ−ベンズイミダゾール−２−イリデンアミン類
EP1896473B1 (en) 2005-06-20 2011-10-19 Tibotec Pharmaceuticals 1-[[2-amino-3-(substituted alkyl)-3h-benzimidazolyl]methyl]-3-subtituted-1,3-dihydro-benzoimidazol-2-ones as inhibitors of respiratory syncytial virus replication
BRPI0612317B8 (pt) * 2005-06-20 2021-05-25 Janssen R & D Ireland benzimidazóis 2-substituídos, seu processo de preparação e composição farmacêutica
CN101203506B (zh) 2005-06-20 2012-02-22 泰博特克药品有限公司 杂环基氨基烷基取代的苯并咪唑
US20130085133A1 (en) * 2010-02-08 2013-04-04 Sourthern Research Institute Office of Commercialization and Intellectual Prop. Anti-viral treatment and assay to screenfor anti-viral agent
TWI501967B (zh) 2010-12-16 2015-10-01 Janssen R&D Ireland 作為呼吸道融合病毒抗病毒劑之氮雜吲哚類
TWI515187B (zh) 2010-12-16 2016-01-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之吲哚類
TWI541241B (zh) * 2010-12-16 2016-07-11 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之咪唑并吡啶類
TWI530495B (zh) 2010-12-16 2016-04-21 健生科學愛爾蘭無限公司 苯并咪唑呼吸道融合病毒抑制劑
TWI527814B (zh) 2010-12-16 2016-04-01 健生科學愛爾蘭無限公司 作為呼吸道融合病毒抗病毒劑之氮雜苯并咪唑類
JP6242810B2 (ja) 2011-12-28 2017-12-06 グローバル・ブラッド・セラピューティクス・インコーポレイテッドＧｌｏｂａｌ Ｂｌｏｏｄ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 置換ベンズアルデヒド化合物および組織酸素化の増加におけるそれらの使用方法
EP2797597B1 (en) 2011-12-28 2020-02-26 Global Blood Therapeutics, Inc. Substituted heteroaryl aldehyde compounds and methods for their use in increasing tissue oxygenation
CN104540817B (zh) 2012-06-15 2017-03-01 爱尔兰詹森科学公司 作为呼吸道合胞病毒抗病毒剂的用杂环取代的1，3‑二氢‑2h‑苯并咪唑‑2‑酮衍生物
US20160083343A1 (en) 2013-03-15 2016-03-24 Global Blood Therapeutics, Inc Compounds and uses thereof for the modulation of hemoglobin
US10100043B2 (en) 2013-03-15 2018-10-16 Global Blood Therapeutics, Inc. Substituted aldehyde compounds and methods for their use in increasing tissue oxygenation
US9458139B2 (en) 2013-03-15 2016-10-04 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US10266551B2 (en) 2013-03-15 2019-04-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
MX2015011769A (es) 2013-03-15 2016-06-02 Global Blood Therapeutics Inc Compuestos y sus usos para modular la hemoglobina.
US20140274961A1 (en) 2013-03-15 2014-09-18 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9604999B2 (en) 2013-03-15 2017-03-28 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US9802900B2 (en) 2013-03-15 2017-10-31 Global Blood Therapeutics, Inc. Bicyclic heteroaryl compounds and uses thereof for the modulation of hemoglobin
US9422279B2 (en) 2013-03-15 2016-08-23 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
US8952171B2 (en) 2013-03-15 2015-02-10 Global Blood Therapeutics, Inc. Compounds and uses thereof for the modulation of hemoglobin
KR20190041548A (ko) 2013-03-15 2019-04-22 글로벌 블러드 테라퓨틱스, 인크. 헤모글로빈 조정을 위한 화합물 및 이의 용도
EA201992707A1 (ru) 2013-11-18 2020-06-30 Глобал Блад Терапьютикс, Инк. Соединения и их применения для модуляции гемоглобина
EA028529B1 (ru) 2014-02-07 2017-11-30 Глобал Блад Терапьютикс, Инк. Кристаллические полиморфные формы свободного основания 2-гидрокси-6-((2-(1-изопропил-1н-пиразол-5-ил)пиридин-3-ил)метокси)бензальдегида
JP2016079168A (ja) * 2014-10-17 2016-05-16 塩野義製薬株式会社 ９員縮合環誘導体
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Also Published As

Publication number Publication date
TR200103806T2 (tr) 2002-06-21
EA005027B1 (ru) 2004-10-28
HRP20010935A2 (en) 2003-06-30
ATE258928T1 (de) 2004-02-15
CN1358181A (zh) 2002-07-10
WO2001000612A2 (en) 2001-01-04
JP2003503402A (ja) 2003-01-28
MY127687A (en) 2006-12-29
NZ515664A (en) 2004-01-30
SI1196409T1 (en) 2004-06-30
HK1045997A1 (zh) 2002-12-20
EE200100688A (et) 2003-04-15
EE04591B1 (et) 2006-02-15
US6747028B1 (en) 2004-06-08
PT1196409E (pt) 2004-06-30
UA74787C2 (en) 2006-02-15
US20070015747A1 (en) 2007-01-18
US7528149B2 (en) 2009-05-05
MXPA02000120A (es) 2002-07-02
CN1210275C (zh) 2005-07-13
DE60008112D1 (en) 2004-03-11
BG106286A (en) 2002-10-31
BG65328B1 (bg) 2008-02-29
KR100731271B1 (ko) 2007-06-21
NO20016369L (no) 2002-02-20
PL200674B1 (pl) 2009-01-30
DK1196409T3 (da) 2004-06-07
TWI278454B (en) 2007-04-11
AU5816600A (en) 2001-01-31
HUP0201869A2 (hu) 2002-11-28
BR0012047A (pt) 2002-03-12
CA2376676A1 (en) 2001-01-04
ES2215683T3 (es) 2004-10-16
EP1196409A2 (en) 2002-04-17
US7179811B2 (en) 2007-02-20
IL147327A (en) 2007-06-03
SK19122001A3 (sk) 2003-01-09
AR035991A1 (es) 2004-08-04
DE60008112T2 (de) 2004-09-16
CA2376676C (en) 2009-01-20
KR20020003884A (ko) 2002-01-15
PL352378A1 (en) 2003-08-25
NO322458B1 (no) 2006-10-09
IL147327A0 (en) 2002-08-14
AU778218B2 (en) 2004-11-25
EP1196409B1 (en) 2004-02-04
EA200200088A1 (ru) 2002-06-27
HUP0201869A3 (en) 2003-12-29
ZA200110479B (en) 2003-03-20
US20070135404A1 (en) 2007-06-14
WO2001000612A3 (en) 2001-03-29

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