DK1697347T3 - 5- eller 6-substituerede benzimidazolderivater som inhibitorer af replikation af respiratorisk syncytial-virus - Google Patents
5- eller 6-substituerede benzimidazolderivater som inhibitorer af replikation af respiratorisk syncytial-virusInfo
- Publication number
- DK1697347T3 DK1697347T3 DK04804954.8T DK04804954T DK1697347T3 DK 1697347 T3 DK1697347 T3 DK 1697347T3 DK 04804954 T DK04804954 T DK 04804954T DK 1697347 T3 DK1697347 T3 DK 1697347T3
- Authority
- DK
- Denmark
- Prior art keywords
- inhibitors
- respiratory syncytial
- syncytial virus
- virus replication
- benzimidazole derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Virology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP03104806 | 2003-12-18 | ||
| US56686704P | 2004-04-30 | 2004-04-30 | |
| PCT/EP2004/053618 WO2005058874A1 (en) | 2003-12-18 | 2004-12-20 | 5- or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK1697347T3 true DK1697347T3 (da) | 2011-06-06 |
Family
ID=43646156
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK04804954.8T DK1697347T3 (da) | 2003-12-18 | 2004-12-20 | 5- eller 6-substituerede benzimidazolderivater som inhibitorer af replikation af respiratorisk syncytial-virus |
Country Status (19)
| Country | Link |
|---|---|
| US (2) | US20070093502A1 (da) |
| EP (1) | EP1697347B1 (da) |
| JP (1) | JP2007514719A (da) |
| KR (1) | KR101123055B1 (da) |
| CN (1) | CN1914196B (da) |
| AR (1) | AR046770A1 (da) |
| AT (1) | ATE499361T1 (da) |
| AU (1) | AU2004298459B2 (da) |
| BR (1) | BRPI0417273A (da) |
| CA (1) | CA2548793A1 (da) |
| DE (1) | DE602004031555D1 (da) |
| DK (1) | DK1697347T3 (da) |
| HR (1) | HRP20110313T1 (da) |
| MX (1) | MXPA06007111A (da) |
| MY (1) | MY142783A (da) |
| RU (1) | RU2369606C2 (da) |
| SI (1) | SI1697347T1 (da) |
| TW (1) | TWI382981B (da) |
| WO (1) | WO2005058874A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2444690T3 (es) * | 2005-06-20 | 2014-02-26 | Janssen R&D Ireland | Bencimidazoles sustituidos con heterociclilaminoalquilo. |
| AR089568A1 (es) | 2011-10-14 | 2014-09-03 | Ambit Biosciences Corp | Compuestos heterociclicos y sus metodos de usos |
| TW201813963A (zh) | 2016-09-23 | 2018-04-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201825465A (zh) | 2016-09-23 | 2018-07-16 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| TW201815787A (zh) | 2016-09-23 | 2018-05-01 | 美商基利科學股份有限公司 | 磷脂醯肌醇3-激酶抑制劑 |
| NZ748072A (en) | 2017-03-20 | 2020-06-26 | Forma Therapeutics Inc | Pyrrolopyrrole compositions as pyruvate kinase (pkr) activators |
| AU2018352695A1 (en) | 2017-10-19 | 2020-05-28 | Effector Therapeutics, Inc. | Benzimidazole-indole inhibitors of Mnk1 and Mnk2 |
| CN113226356A (zh) | 2018-09-19 | 2021-08-06 | 福马治疗股份有限公司 | 活化丙酮酸激酶r |
| US12053458B2 (en) | 2018-09-19 | 2024-08-06 | Novo Nordisk Health Care Ag | Treating sickle cell disease with a pyruvate kinase R activating compound |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4025621A (en) * | 1975-01-09 | 1977-05-24 | Purdy Clarence L | Method of curing and providing immunity from viral infections |
| CA1140119A (en) | 1978-04-03 | 1983-01-25 | Joseph Torremans | N-heterocyclyl-4-piperidinamines |
| US4556660A (en) | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| US4634704A (en) | 1983-10-06 | 1987-01-06 | Janssen Pharmaceutica, N.V. | Anti-allergic five membered heterocyclic ring containing N-(bicyclic heterocycyl)-4-piperidinamines |
| KR100190299B1 (ko) | 1990-07-19 | 1999-06-01 | 디르크 반테 | 신규한 옥사졸릴 유도체 |
| CA2376781A1 (en) * | 1999-06-28 | 2001-01-04 | Janssen Pharmaceutica N.V. | Benzimidazoles and imidazopyridines as respiratory syncytial virus replication inhibitors |
| CN1210275C (zh) * | 1999-06-28 | 2005-07-13 | 詹森药业有限公司 | 呼吸道合胞病毒复制抑制剂 |
| DE60033859T2 (de) * | 1999-06-28 | 2007-11-08 | Janssen Pharmaceutica N.V. | Hemmer des Respiratorischen Syncytial Virus |
| US20040157866A1 (en) * | 2001-04-30 | 2004-08-12 | Hisashi Takasugi | Amide compounds |
| US7030150B2 (en) * | 2001-05-11 | 2006-04-18 | Trimeris, Inc. | Benzimidazole compounds and antiviral uses thereof |
| FR2833948B1 (fr) * | 2001-12-21 | 2004-02-06 | Sod Conseils Rech Applic | Nouveaux derives de benzimidazole et leur utilisation en tant que medicament |
-
2004
- 2004-12-20 US US10/596,521 patent/US20070093502A1/en not_active Abandoned
- 2004-12-20 CN CN2004800416543A patent/CN1914196B/zh active Active
- 2004-12-20 DK DK04804954.8T patent/DK1697347T3/da active
- 2004-12-20 MY MYPI20045258A patent/MY142783A/en unknown
- 2004-12-20 CA CA002548793A patent/CA2548793A1/en not_active Abandoned
- 2004-12-20 JP JP2006544465A patent/JP2007514719A/ja active Pending
- 2004-12-20 DE DE602004031555T patent/DE602004031555D1/de active Active
- 2004-12-20 EP EP04804954A patent/EP1697347B1/en active Active
- 2004-12-20 WO PCT/EP2004/053618 patent/WO2005058874A1/en active Application Filing
- 2004-12-20 BR BRPI0417273-6A patent/BRPI0417273A/pt not_active Application Discontinuation
- 2004-12-20 AT AT04804954T patent/ATE499361T1/de not_active IP Right Cessation
- 2004-12-20 SI SI200431657T patent/SI1697347T1/sl unknown
- 2004-12-20 TW TW093139735A patent/TWI382981B/zh not_active IP Right Cessation
- 2004-12-20 KR KR1020067014248A patent/KR101123055B1/ko not_active IP Right Cessation
- 2004-12-20 MX MXPA06007111A patent/MXPA06007111A/es active IP Right Grant
- 2004-12-20 AR ARP040104808A patent/AR046770A1/es not_active Application Discontinuation
- 2004-12-20 RU RU2006125727/04A patent/RU2369606C2/ru not_active IP Right Cessation
- 2004-12-20 AU AU2004298459A patent/AU2004298459B2/en not_active Ceased
-
2008
- 2008-10-17 US US12/253,450 patent/US8278455B2/en active Active
-
2011
- 2011-04-29 HR HR20110313T patent/HRP20110313T1/hr unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HRP20110313T1 (hr) | 2011-05-31 |
| WO2005058874A1 (en) | 2005-06-30 |
| EP1697347B1 (en) | 2011-02-23 |
| AU2004298459B2 (en) | 2011-03-17 |
| SI1697347T1 (sl) | 2011-06-30 |
| ATE499361T1 (de) | 2011-03-15 |
| JP2007514719A (ja) | 2007-06-07 |
| DE602004031555D1 (de) | 2011-04-07 |
| EP1697347A1 (en) | 2006-09-06 |
| AR046770A1 (es) | 2005-12-21 |
| MXPA06007111A (es) | 2006-08-23 |
| KR101123055B1 (ko) | 2012-04-12 |
| US20070093502A1 (en) | 2007-04-26 |
| CN1914196B (zh) | 2012-01-25 |
| US20090062278A1 (en) | 2009-03-05 |
| CN1914196A (zh) | 2007-02-14 |
| RU2369606C2 (ru) | 2009-10-10 |
| AU2004298459A1 (en) | 2005-06-30 |
| TWI382981B (zh) | 2013-01-21 |
| US8278455B2 (en) | 2012-10-02 |
| MY142783A (en) | 2010-12-31 |
| TW200531970A (en) | 2005-10-01 |
| KR20060127047A (ko) | 2006-12-11 |
| BRPI0417273A (pt) | 2007-03-27 |
| CA2548793A1 (en) | 2005-06-30 |
| RU2006125727A (ru) | 2008-01-27 |
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