SI1196410T1 - Inhibitorji replikacije respiratornega sincitialnega virusa - Google Patents

Inhibitorji replikacije respiratornega sincitialnega virusa

Info

Publication number
SI1196410T1
SI1196410T1 SI200030358T SI200030358T SI1196410T1 SI 1196410 T1 SI1196410 T1 SI 1196410T1 SI 200030358 T SI200030358 T SI 200030358T SI 200030358 T SI200030358 T SI 200030358T SI 1196410 T1 SI1196410 T1 SI 1196410T1
Authority
SI
Slovenia
Prior art keywords
respiratory syncytial
syncytial virus
virus replication
replication inhibitors
inhibitors
Prior art date
Application number
SI200030358T
Other languages
English (en)
Inventor
Frans Eduard Janssens
Jean Fernand Armand Janssen-Cilag S.A. LACRAMPE
Jerome Emile G. Janssen-Cilag S.A. GUILLEMONT
Marc Gaston Janssen-Cilag S.A. VENET
Koenraad Jozef Lodewijk Marcel Andries
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of SI1196410T1 publication Critical patent/SI1196410T1/sl

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
SI200030358T 1999-06-28 2000-06-20 Inhibitorji replikacije respiratornega sincitialnega virusa SI1196410T1 (sl)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP99202089 1999-06-28
PCT/EP2000/005677 WO2001000615A1 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors
EP00936899A EP1196410B1 (en) 1999-06-28 2000-06-20 Respiratory syncytial virus replication inhibitors

Publications (1)

Publication Number Publication Date
SI1196410T1 true SI1196410T1 (sl) 2004-08-31

Family

ID=8240374

Family Applications (1)

Application Number Title Priority Date Filing Date
SI200030358T SI1196410T1 (sl) 1999-06-28 2000-06-20 Inhibitorji replikacije respiratornega sincitialnega virusa

Country Status (34)

Country Link
US (2) US7071192B1 (sl)
EP (2) EP1400519B1 (sl)
JP (1) JP2003503403A (sl)
KR (1) KR100731273B1 (sl)
CN (1) CN1171887C (sl)
AR (1) AR024495A1 (sl)
AT (2) ATE259796T1 (sl)
AU (1) AU774829B2 (sl)
BG (1) BG65373B1 (sl)
BR (1) BR0011997A (sl)
CA (1) CA2376785A1 (sl)
CZ (1) CZ20014573A3 (sl)
DE (2) DE60008382T2 (sl)
DK (1) DK1196410T3 (sl)
EA (1) EA004746B1 (sl)
EE (1) EE04592B1 (sl)
ES (2) ES2215670T3 (sl)
HK (1) HK1045998B (sl)
HR (2) HRP20010934A2 (sl)
HU (1) HUP0201789A3 (sl)
IL (2) IL147328A0 (sl)
MX (1) MXPA02000117A (sl)
MY (1) MY129810A (sl)
NO (1) NO321599B1 (sl)
NZ (1) NZ515392A (sl)
PL (1) PL200694B1 (sl)
PT (1) PT1196410E (sl)
SI (1) SI1196410T1 (sl)
SK (1) SK18952001A3 (sl)
TR (2) TR200103805T2 (sl)
TW (1) TWI267513B (sl)
UA (1) UA75866C2 (sl)
WO (1) WO2001000615A1 (sl)
ZA (1) ZA200110473B (sl)

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US6506738B1 (en) 2000-09-27 2003-01-14 Bristol-Myers Squibb Company Benzimidazolone antiviral agents
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ATE300541T1 (de) 2000-12-15 2005-08-15 Glaxo Group Ltd Pyrazolopyridinderivate
US6774134B2 (en) 2000-12-20 2004-08-10 Bristol-Myers Squibb Company Heterocyclic substituted 2-methyl-benzimidazole antiviral agents
WO2002072581A2 (en) 2001-03-08 2002-09-19 Smithkline Beecham Corporation Pyrazolopyriadine derivatives
JP4237497B2 (ja) 2001-03-30 2009-03-11 スミスクライン ビーチャム コーポレーション ピラゾロピリジン類、その調製方法及びその治療用化合物としての使用
DE60212949T2 (de) 2001-04-10 2007-01-04 Smithkline Beecham Corp. Antivirale pyrazolopyridin verbindungen
WO2002088124A2 (en) 2001-04-27 2002-11-07 Smithkline Beecham Corporation Pyrazolo'1,5-a!pyridine derivatives
US7030150B2 (en) * 2001-05-11 2006-04-18 Trimeris, Inc. Benzimidazole compounds and antiviral uses thereof
EP1401836B1 (en) 2001-06-21 2006-08-23 SmithKline Beecham Corporation Imidazo¬1,2-a|pyridine derivatives for the prophylaxis and treatment of herpes viral infections
ES2262893T3 (es) 2001-10-05 2006-12-01 Smithkline Beecham Corporation Derivados de imidazo-piridina para su uso en el tratamiento de infeccion virica por herpes.
US6919331B2 (en) 2001-12-10 2005-07-19 Bristol-Myers Squibb Company Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents
US7199120B2 (en) 2001-12-11 2007-04-03 Smithkline Beecham Corporation Pyrazolo-pyridine derivatives as antiherpes agents
US7244847B2 (en) * 2002-02-06 2007-07-17 Isis Pharmaceuticals, Inc. Benzimidazole compounds
EP1545513A2 (en) 2002-08-09 2005-06-29 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
EP1539691A2 (en) 2002-08-09 2005-06-15 Viropharma Incorporated Compounds, compositions and methods for treating or preventing pneumovirus infection and associated diseases
US7153863B2 (en) 2002-10-03 2006-12-26 Smithkline Beecham Corporation Therapeutic compounds based on pyrazolopyridline derivatives
WO2005042530A1 (en) * 2003-10-30 2005-05-12 Boehringer Ingelheim (Canada) Ltd. Rsv polymerase inhibitors
CN1894236B (zh) * 2003-12-18 2011-08-17 泰博特克药品有限公司 作为呼吸道合胞病毒复制抑制剂的氨基-苯并咪唑类衍生物
AU2004298456B2 (en) 2003-12-18 2011-04-07 Tibotec Pharmaceuticals Ltd. Piperidine-amino-benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
AR046959A1 (es) * 2003-12-18 2006-01-04 Tibotec Pharm Ltd Morfolinilo que contiene bencimidazoles como inhibidores de la replicacion del virus sincitial respiratorio
RU2332414C2 (ru) * 2003-12-18 2008-08-27 Тиботек Фармасьютикалз Лтд. Производные аминобензимидазолов в качестве ингибиторов репликации респираторного синцитиального вируса
US20070093502A1 (en) * 2003-12-18 2007-04-26 Jean-Francois Bonfanti 5- Or 6-substituted benzimidazole derivatives as inhibitors of respiratory syncytial virus replication
EP1697343B1 (en) 2003-12-18 2009-07-01 Tibotec Pharmaceuticals Ltd. Aminobenzimidazoles and benzimidazoles as inhibitors of respiratory syncytial virus replication
RU2410382C2 (ru) * 2005-03-17 2011-01-27 Тиботек Фармасьютикалз Лтд 1, 3-дигидробензимидазол-2-илиденовые амины в качестве ингибиторов репликации респираторного синцитиального вируса
CN101203506B (zh) * 2005-06-20 2012-02-22 泰博特克药品有限公司 杂环基氨基烷基取代的苯并咪唑
JP5078887B2 (ja) * 2005-06-20 2012-11-21 テイボテク・フアーマシユーチカルズ 呼吸器シンシチウムウイルスに活性をもつ、１−（２−アミノ−３−（置換アルキル）−３ｈ−ベンズイミダゾイルメチル）−３−置換−１，３−ジヒドロ−ベンゾイミダゾル−２−オン
CL2008001003A1 (es) 2007-04-11 2008-10-17 Actelion Pharmaceuticals Ltd Compuestos derivados de oxazolidinona; composicion farmaceutica que comprende a dichos compuestos; y su uso para preparar un medicamento para tratar una infeccion bacteriana.
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US8993604B2 (en) 2009-06-30 2015-03-31 Siga Technologies, Inc. Treatment and prevention of dengue virus infections
KR20120049852A (ko) * 2009-06-30 2012-05-17 시가 테크놀로지스, 인크. 뎅기 바이러스 감염의 치료 및 예방
US9567330B2 (en) 2011-07-15 2017-02-14 Shionogi & Co., Ltd. Azabenzimidazole derivative having AMPK-activating activity
EA201590197A1 (ru) * 2012-08-23 2015-07-30 Алиос Биофарма, Инк. Соединения для лечения парамиксовирусных вирусных инфекций
JP2016079168A (ja) 2014-10-17 2016-05-16 塩野義製薬株式会社 ９員縮合環誘導体

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Also Published As

Publication number Publication date
EA200200086A1 (ru) 2002-06-27
ATE259796T1 (de) 2004-03-15
EE200100694A (et) 2003-02-17
TR200500707T2 (tr) 2005-04-21
UA75866C2 (en) 2006-06-15
EP1400519A1 (en) 2004-03-24
KR100731273B1 (ko) 2007-06-21
BR0011997A (pt) 2002-03-05
AU774829B2 (en) 2004-07-08
TR200103805T2 (tr) 2002-06-21
WO2001000615A1 (en) 2001-01-04
CN1358182A (zh) 2002-07-10
EA004746B1 (ru) 2004-08-26
HUP0201789A2 (hu) 2002-11-28
US7071192B1 (en) 2006-07-04
KR20020000815A (ko) 2002-01-05
BG65373B1 (bg) 2008-04-30
CN1171887C (zh) 2004-10-20
ATE356121T1 (de) 2007-03-15
IL147328A0 (en) 2002-08-14
JP2003503403A (ja) 2003-01-28
DE60033859T2 (de) 2007-11-08
US7407969B2 (en) 2008-08-05
MXPA02000117A (es) 2002-07-02
US20060058309A1 (en) 2006-03-16
SK18952001A3 (sk) 2002-11-06
HUP0201789A3 (en) 2003-12-29
DE60008382D1 (en) 2004-03-25
PT1196410E (pt) 2004-07-30
PL352385A1 (en) 2003-08-25
NZ515392A (en) 2004-03-26
CZ20014573A3 (cs) 2002-05-15
AR024495A1 (es) 2002-10-02
DK1196410T3 (da) 2004-06-28
WO2001000615A8 (en) 2002-01-10
HRP20080390A2 (en) 2008-12-31
HRP20010934A2 (en) 2003-06-30
NO321599B1 (no) 2006-06-06
DE60033859D1 (de) 2007-04-19
AU5222200A (en) 2001-01-31
PL200694B1 (pl) 2009-01-30
EP1196410B1 (en) 2004-02-18
NO20016370D0 (no) 2001-12-27
HK1045998B (zh) 2005-06-03
HK1045998A1 (en) 2002-12-20
ZA200110473B (en) 2003-03-20
TWI267513B (en) 2006-12-01
ES2283716T3 (es) 2007-11-01
DE60008382T2 (de) 2004-12-02
EP1196410A1 (en) 2002-04-17
CA2376785A1 (en) 2001-01-04
ES2215670T3 (es) 2004-10-16
BG106288A (en) 2002-10-31
EE04592B1 (et) 2006-02-15
NO20016370L (no) 2001-12-27
IL147328A (en) 2007-06-03
MY129810A (en) 2007-05-31
EP1400519B1 (en) 2007-03-07

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