SI1007017T2 - Budezonid/formoterol formulacija za inhaliranje, ki ima nasipno gostoto od 0,30 g/ml do 0,36 g/ml, postopek za pripravo formulacije in njena uporaba - Google Patents
Budezonid/formoterol formulacija za inhaliranje, ki ima nasipno gostoto od 0,30 g/ml do 0,36 g/ml, postopek za pripravo formulacije in njena uporabaInfo
- Publication number
- SI1007017T2 SI1007017T2 SI9830754T SI9830754T SI1007017T2 SI 1007017 T2 SI1007017 T2 SI 1007017T2 SI 9830754 T SI9830754 T SI 9830754T SI 9830754 T SI9830754 T SI 9830754T SI 1007017 T2 SI1007017 T2 SI 1007017T2
- Authority
- SI
- Slovenia
- Prior art keywords
- formulation
- budesonide
- inhalation
- preparing
- bulk density
- Prior art date
Links
- 238000009472 formulation Methods 0.000 title 2
- 239000000203 mixture Substances 0.000 title 2
- PJFHZKIDENOSJB-UHFFFAOYSA-N Budesonide/formoterol Chemical compound C1=CC(OC)=CC=C1CC(C)NCC(O)C1=CC=C(O)C(NC=O)=C1.C1CC2=CC(=O)C=CC2(C)C2C1C1CC3OC(CCC)OC3(C(=O)CO)C1(C)CC2O PJFHZKIDENOSJB-UHFFFAOYSA-N 0.000 title 1
- 229940080593 budesonide / formoterol Drugs 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/16—Amides, e.g. hydroxamic acids
- A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
- A61K31/167—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide having the nitrogen of a carboxamide group directly attached to the aromatic ring, e.g. lidocaine, paracetamol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Otolaryngology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9700135A SE9700135D0 (sv) | 1997-01-20 | 1997-01-20 | New formulation |
| PCT/SE1998/000040 WO1998031352A1 (en) | 1997-01-20 | 1998-01-13 | New formulation for inhalation having a poured bulk density of 0.28 to 0.38 g/ml, a process for preparing the formulation and the use thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SI1007017T1 SI1007017T1 (sl) | 2005-06-30 |
| SI1007017T2 true SI1007017T2 (sl) | 2011-03-31 |
Family
ID=20405455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SI9830754T SI1007017T2 (sl) | 1997-01-20 | 1998-01-13 | Budezonid/formoterol formulacija za inhaliranje, ki ima nasipno gostoto od 0,30 g/ml do 0,36 g/ml, postopek za pripravo formulacije in njena uporaba |
Country Status (34)
| Country | Link |
|---|---|
| US (2) | US6030604A (sl) |
| EP (1) | EP1007017B2 (sl) |
| JP (1) | JP2010059181A (sl) |
| KR (1) | KR100528416B1 (sl) |
| CN (1) | CN1271993C (sl) |
| AR (1) | AR011080A1 (sl) |
| AT (1) | ATE288260T1 (sl) |
| AU (1) | AU731192B2 (sl) |
| BR (1) | BR9811249A (sl) |
| CA (1) | CA2277913C (sl) |
| CZ (1) | CZ296301B6 (sl) |
| DE (1) | DE69828886T3 (sl) |
| DK (1) | DK1007017T4 (sl) |
| EE (1) | EE03951B1 (sl) |
| ES (1) | ES2235311T5 (sl) |
| HU (1) | HU228622B1 (sl) |
| ID (1) | ID21865A (sl) |
| IL (1) | IL130838A (sl) |
| IS (1) | IS2788B (sl) |
| MY (1) | MY132999A (sl) |
| NO (1) | NO327426B1 (sl) |
| NZ (1) | NZ336594A (sl) |
| PL (1) | PL192115B1 (sl) |
| PT (1) | PT1007017E (sl) |
| RU (1) | RU2194497C2 (sl) |
| SA (1) | SA98180818B1 (sl) |
| SE (1) | SE9700135D0 (sl) |
| SI (1) | SI1007017T2 (sl) |
| SK (1) | SK283950B6 (sl) |
| TR (1) | TR199901690T2 (sl) |
| TW (1) | TW557217B (sl) |
| UA (1) | UA57764C2 (sl) |
| WO (1) | WO1998031352A1 (sl) |
| ZA (1) | ZA9878B (sl) |
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| SE9700135D0 (sv) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
| US6495167B2 (en) | 1997-03-20 | 2002-12-17 | Schering Corporation | Preparation of powder agglomerates |
| US6503537B2 (en) | 1997-03-20 | 2003-01-07 | Schering Corporation | Preparation of powder agglomerates |
| SE9703407D0 (sv) * | 1997-09-19 | 1997-09-19 | Astra Ab | New use |
| SE9802073D0 (sv) | 1998-06-11 | 1998-06-11 | Astra Ab | New use |
| GB9826286D0 (en) * | 1998-12-01 | 1999-01-20 | Rhone Poulence Rorer Limited | Process |
| GB9826284D0 (en) * | 1998-12-01 | 1999-01-20 | Rhone Poulence Rorer Limited | Process |
| AU1786199A (en) * | 1998-12-11 | 2000-07-03 | Pharmachemie B.V. | Pharmaceutical preparation for inhalation of an opioid |
| US8722668B2 (en) * | 1998-12-23 | 2014-05-13 | Daryl W. Hochman | Methods and compositions for the treatment of neuropathic pain and neuropsychiatric disorders |
| AR022695A1 (es) * | 1999-01-28 | 2002-09-04 | Schering Corp | PORTADOR SoLIDO PARTICULADO Y MÉTODO PARA PROVEER CONTROL DE LA PARTICULADA PARA LA DISTRIBUCIoN DE TAMANO DE PARTíCULAS Y DE CONTENIDO AMORFO CONVERTIBLE DURANTE SU PREPARACION |
| US6623760B1 (en) * | 1999-01-28 | 2003-09-23 | Schering Corporation | Method of preparing particles for agglomeration |
| GB9903759D0 (en) * | 1999-02-18 | 1999-04-14 | Novartis Ag | Organic compounds |
| GB9904919D0 (en) * | 1999-03-03 | 1999-04-28 | Novartis Ag | Organic compounds |
| CA2369262A1 (en) * | 1999-04-13 | 2000-10-19 | Sudha Nagarajan | Pulmonary administration of dry powder formulations for treating infertility |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1429184A (en) * | 1972-04-20 | 1976-03-24 | Allen & Hanburys Ltd | Physically anti-inflammatory steroids for use in aerosols |
| US4161516A (en) † | 1975-07-25 | 1979-07-17 | Fisons Limited | Composition for treating airway disease |
| GB1571629A (en) * | 1977-11-30 | 1980-07-16 | Fisons Ltd | Pharmaceutical compositions containing beclomethasone dipropionate |
| ATE23272T1 (de) * | 1981-07-08 | 1986-11-15 | Draco Ab | Pulverinhalator. |
| SE438261B (sv) * | 1981-07-08 | 1985-04-15 | Draco Ab | Anvendning i dosinhalator av ett perforerat membran |
| EP0072046B1 (en) * | 1981-07-24 | 1986-01-15 | FISONS plc | Inhalation drugs, methods for their production and pharmaceutical formulations containing them |
| GB8825541D0 (en) † | 1988-11-01 | 1988-12-07 | Fisons Plc | Formulation |
| WO1990013327A1 (en) * | 1989-04-28 | 1990-11-15 | Riker Laboratories, Inc. | Dry powder inhalation device |
| US5176132A (en) * | 1989-05-31 | 1993-01-05 | Fisons Plc | Medicament inhalation device and formulation |
| DK0441740T3 (da) † | 1990-01-29 | 1993-11-08 | Ciba Geigy Ag | Fremgangsmåde og apparat til dosering af et firkornet pulver |
| US5192548A (en) * | 1990-04-30 | 1993-03-09 | Riker Laboratoires, Inc. | Device |
| SE9100341D0 (sv) * | 1991-02-04 | 1991-02-04 | Astra Ab | Novel steroids |
| SE9100342D0 (sv) * | 1991-02-04 | 1991-02-04 | Astra Ab | Novel steroid esters |
| SE9302777D0 (sv) * | 1993-08-27 | 1993-08-27 | Astra Ab | Process for conditioning substances |
| SE9101090D0 (sv) * | 1991-04-11 | 1991-04-11 | Astra Ab | Process for conditioning of water-soluble substances |
| EP1092430B1 (en) * | 1991-06-10 | 2003-08-06 | Schering Corporation | Non-chlorofluorocarbon aerosol formulations |
| US5736124A (en) * | 1991-12-12 | 1998-04-07 | Glaxo Group Limited | Aerosol formulations containing P134a and particulate medicament |
| WO1993011773A1 (en) * | 1991-12-18 | 1993-06-24 | Aktiebolaget Astra | New combination of formoterol and budesonide |
| US5355872B1 (en) * | 1992-03-04 | 1998-10-20 | John H Riggs | Low flow rate nebulizer apparatus and method of nebulization |
| DE69332240T2 (de) † | 1992-06-12 | 2003-04-10 | Teijin Ltd., Osaka | Ultrafeines pulver zur inhalation und dessen herstellung |
| EP0665010B1 (en) * | 1992-10-16 | 2002-09-11 | Nippon Shinyaku Company, Limited | Method of manufacturing wax matrices |
| WO1995005147A1 (en) * | 1993-08-18 | 1995-02-23 | Unilever Plc | Shaving composition |
| IS1736B (is) * | 1993-10-01 | 1999-12-30 | Astra Ab | Aðferð og tæki sem stuðla að aukinni samloðun agna |
| DK0721331T3 (da) † | 1993-10-01 | 2002-02-11 | Astrazeneca Ab | Fremgangsmåde |
| GB9404945D0 (en) † | 1994-03-15 | 1994-04-27 | Glaxo Group Ltd | Pharmaceutical composition |
| US5503869A (en) * | 1994-10-21 | 1996-04-02 | Glaxo Wellcome Inc. | Process for forming medicament carrier for dry powder inhalator |
| US5647347A (en) * | 1994-10-21 | 1997-07-15 | Glaxo Wellcome Inc. | Medicament carrier for dry powder inhalator |
| US5654007A (en) * | 1995-06-07 | 1997-08-05 | Inhale Therapeutic Systems | Methods and system for processing dispersible fine powders |
| SE9603669D0 (sv) * | 1996-10-08 | 1996-10-08 | Astra Ab | New combination |
| SE9700135D0 (sv) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
-
1997
- 1997-01-20 SE SE9700135A patent/SE9700135D0/xx unknown
-
1998
- 1998-01-06 ZA ZA9878A patent/ZA9878B/xx unknown
- 1998-01-09 US US09/004,902 patent/US6030604A/en not_active Expired - Lifetime
- 1998-01-13 BR BR9811249-0A patent/BR9811249A/pt not_active Application Discontinuation
- 1998-01-13 CZ CZ0255799A patent/CZ296301B6/cs not_active IP Right Cessation
- 1998-01-13 PT PT98901618T patent/PT1007017E/pt unknown
- 1998-01-13 IL IL13083898A patent/IL130838A/xx not_active IP Right Cessation
- 1998-01-13 DE DE69828886T patent/DE69828886T3/de not_active Expired - Lifetime
- 1998-01-13 PL PL334527A patent/PL192115B1/pl unknown
- 1998-01-13 HU HU0000714A patent/HU228622B1/hu unknown
- 1998-01-13 ID IDW990663A patent/ID21865A/id unknown
- 1998-01-13 NZ NZ336594A patent/NZ336594A/xx not_active IP Right Cessation
- 1998-01-13 AU AU57859/98A patent/AU731192B2/en not_active Expired
- 1998-01-13 EE EEP199900295A patent/EE03951B1/xx unknown
- 1998-01-13 AT AT98901618T patent/ATE288260T1/de active
- 1998-01-13 CA CA002277913A patent/CA2277913C/en not_active Expired - Lifetime
- 1998-01-13 WO PCT/SE1998/000040 patent/WO1998031352A1/en not_active Ceased
- 1998-01-13 SK SK959-99A patent/SK283950B6/sk not_active IP Right Cessation
- 1998-01-13 ES ES98901618T patent/ES2235311T5/es not_active Expired - Lifetime
- 1998-01-13 UA UA99074044A patent/UA57764C2/uk unknown
- 1998-01-13 TR TR1999/01690T patent/TR199901690T2/xx unknown
- 1998-01-13 RU RU99118587/14A patent/RU2194497C2/ru active
- 1998-01-13 KR KR10-1999-7006414A patent/KR100528416B1/ko not_active Expired - Lifetime
- 1998-01-13 SI SI9830754T patent/SI1007017T2/sl unknown
- 1998-01-13 DK DK98901618.3T patent/DK1007017T4/da active
- 1998-01-13 EP EP98901618A patent/EP1007017B2/en not_active Expired - Lifetime
- 1998-01-13 CN CNB988019000A patent/CN1271993C/zh not_active Expired - Lifetime
- 1998-01-15 MY MYPI98000164A patent/MY132999A/en unknown
- 1998-01-19 AR ARP980100224A patent/AR011080A1/es not_active Application Discontinuation
- 1998-02-10 SA SA98180818A patent/SA98180818B1/ar unknown
- 1998-03-11 TW TW087103589A patent/TW557217B/zh not_active IP Right Cessation
-
1999
- 1999-07-06 IS IS5108A patent/IS2788B/is unknown
- 1999-07-19 NO NO19993539A patent/NO327426B1/no not_active IP Right Cessation
- 1999-11-02 US US09/431,916 patent/US6287540B1/en not_active Expired - Lifetime
-
2009
- 2009-11-06 JP JP2009255070A patent/JP2010059181A/ja active Pending
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