SI0885220T1 - Tropane-derivatives, their preparation and use - Google Patents
Tropane-derivatives, their preparation and useInfo
- Publication number
- SI0885220T1 SI0885220T1 SI9730163T SI9730163T SI0885220T1 SI 0885220 T1 SI0885220 T1 SI 0885220T1 SI 9730163 T SI9730163 T SI 9730163T SI 9730163 T SI9730163 T SI 9730163T SI 0885220 T1 SI0885220 T1 SI 0885220T1
- Authority
- SI
- Slovenia
- Prior art keywords
- disorders
- derivatives
- tropane
- monoamine neurotransmitter
- uptake
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Psychiatry (AREA)
- Addiction (AREA)
- Psychology (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Child & Adolescent Psychology (AREA)
- Obesity (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK19496 | 1996-02-22 | ||
PCT/EP1997/000850 WO1997030997A1 (en) | 1996-02-22 | 1997-02-21 | Tropane-derivatives, their preparation and use |
EP97903355A EP0885220B1 (en) | 1996-02-22 | 1997-02-21 | Tropane-derivatives, their preparation and use |
Publications (1)
Publication Number | Publication Date |
---|---|
SI0885220T1 true SI0885220T1 (en) | 2001-12-31 |
Family
ID=8090830
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI9730163T SI0885220T1 (en) | 1996-02-22 | 1997-02-21 | Tropane-derivatives, their preparation and use |
Country Status (32)
Country | Link |
---|---|
US (3) | US6288079B1 (et) |
EP (2) | EP0885220B1 (et) |
JP (1) | JP3238414B2 (et) |
KR (1) | KR100446571B1 (et) |
CN (1) | CN1077574C (et) |
AT (1) | ATE203023T1 (et) |
AU (1) | AU720358B2 (et) |
BG (1) | BG63945B1 (et) |
BR (1) | BR9707636A (et) |
CA (1) | CA2244773C (et) |
CZ (1) | CZ287007B6 (et) |
DE (1) | DE69705608T2 (et) |
DK (1) | DK0885220T3 (et) |
EE (1) | EE04751B1 (et) |
ES (1) | ES2159839T3 (et) |
GR (1) | GR3036829T3 (et) |
HK (1) | HK1018957A1 (et) |
HU (1) | HU228356B1 (et) |
IL (1) | IL125146A (et) |
IS (1) | IS1824B (et) |
NO (1) | NO318731B1 (et) |
NZ (1) | NZ330886A (et) |
PL (1) | PL185132B1 (et) |
PT (1) | PT885220E (et) |
RU (1) | RU2167876C2 (et) |
SG (1) | SG99853A1 (et) |
SI (1) | SI0885220T1 (et) |
SK (1) | SK281813B6 (et) |
TR (1) | TR199801641T2 (et) |
UA (1) | UA49872C2 (et) |
WO (1) | WO1997030997A1 (et) |
ZA (1) | ZA971525B (et) |
Families Citing this family (77)
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KR100615867B1 (ko) * | 1998-09-30 | 2006-08-25 | 니혼 메디피직스 가부시키가이샤 | 광학 활성 트로피논 모노카르복실산 유도체의 제조 방법 |
AUPP627498A0 (en) | 1998-10-02 | 1998-10-22 | University Of Queensland, The | Novel peptides - i |
EP1397358A1 (en) * | 2001-05-23 | 2004-03-17 | Neurosearch A/S | Tropane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
JP4071012B2 (ja) * | 2001-10-11 | 2008-04-02 | オーガニクス インコーポレーテッド | セロトニンの伝達抑制物質 |
WO2003037313A2 (en) * | 2001-10-31 | 2003-05-08 | Recovery Pharmaceuticals, Inc. | Methods for the treatment of addiction |
WO2003045388A1 (en) * | 2001-11-30 | 2003-06-05 | Neurosearch A/S | Tropane derivatives having dopamine reuptake inhibitor activity for the treatment of ischemic diseases |
MXPA04011859A (es) * | 2002-05-30 | 2005-03-31 | Neurosearch As | Inhibidores de la receptacion de monoamina triple para el tratamiento de dolor cronico. |
ATE461174T1 (de) | 2002-11-01 | 2010-04-15 | Neurosearch As | Neue piperidinderivate und deren verwendung als monoaminneurotransmitter-wiederaufnahmehemmer |
WO2004050688A1 (en) | 2002-12-02 | 2004-06-17 | Xenome Ltd | NOVEL χ-CONOTOXIN PEPTIDES (-II) |
EP1572725B1 (en) | 2002-12-02 | 2012-02-29 | Xenome Ltd | Chi-conotoxin peptides having a n-terminal pyroglutamic acid |
CN100372850C (zh) * | 2003-02-12 | 2008-03-05 | 神经研究公司 | 新的8-氮杂-双环[3.2.1]辛烷衍生物和它们作为单胺神经递质再摄取抑制剂的用途 |
CN100551924C (zh) * | 2003-02-12 | 2009-10-21 | 神经研究公司 | 8-氮杂-双环[3.2.1]辛烷衍生物和它们作为单胺神经递质再摄取抑制剂的用途 |
US7247643B2 (en) | 2003-02-12 | 2007-07-24 | Neurosearch A/S | 8-aza-bicyclo (3.2.1) octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
NZ541248A (en) | 2003-02-12 | 2008-04-30 | Neurosearch As | Novel 8-aza-bicyclo[3.2.1]octane derivatives and their use as monoamine neurotransmitter re-uptake inhibitors |
UA82517C2 (uk) | 2003-06-24 | 2008-04-25 | Ньюросерч А/С | Нові похідні 8-аза-біцикло[3.2.1]октану та їх застосування як інгібіторів ресорбції моноамінових медіаторів |
AR045141A1 (es) * | 2003-07-31 | 2005-10-19 | Neurosearch As | Sales de tartrato de 2- metoximetil-3-(3,4-diclorofenil)-8-azabiciclo (3,2,1) octano. composiciones farmaceuticas que los contienen y usos de las mismas. |
WO2005033107A1 (en) | 2003-10-03 | 2005-04-14 | Pfizer Limited | Imidazopyridine substituted tropane derivatives with ccr5 receptor antagonist activity for the treatment of hiv and inflammation |
NZ547152A (en) | 2003-10-16 | 2009-12-24 | Neurosearch As | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and an acetylcholinesterase inhibitor |
RU2377987C2 (ru) * | 2003-11-18 | 2010-01-10 | Бёрингер Ингельхайм Интернациональ Гмбх | Твердая лекарственная форма |
JP2007518755A (ja) * | 2004-01-22 | 2007-07-12 | ノイロサーチ アクティーゼルスカブ | モノアミン神経伝達物質再取り込み阻害剤及びn−メチル−d−アスパラギン酸(nmda)受容体アンタゴニストを含む医薬組成物 |
WO2005070428A1 (en) * | 2004-01-22 | 2005-08-04 | Boehringer Ingelheim International Gmbh | Pharmaceutical composition comprising a monoamine neurotransmitter re-uptake inhibitor and a dopamine agonist |
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DE102004004965B4 (de) | 2004-01-31 | 2006-01-05 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Verfahren zur Herstellung eines 2-(Ethoxymethyl)-tropanderivates |
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UA95454C2 (uk) | 2005-07-15 | 2011-08-10 | Амр Текнолоджи, Інк. | Арил- і гетероарилзаміщені тетрагідробензазепіни і їх застосування для блокування зворотного захоплення норепінефрину, допаміну і серотоніну |
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EA033298B1 (ru) | 2015-03-03 | 2019-09-30 | Саниона А/С | Комбинированная лекарственная форма тезофензина и метопролола |
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JP2852467B2 (ja) * | 1991-11-15 | 1999-02-03 | リサーチ・トライアングル・インスティテュート | コカイン受容体結合性リガント |
AU672644B2 (en) * | 1992-12-23 | 1996-10-10 | Neurosearch A/S | Aryl substituted heterocyclic compounds |
AU672052B2 (en) * | 1992-12-23 | 1996-09-19 | Neurosearch A/S | Antidepressant and antiparkinsonian compounds |
AU671163B2 (en) * | 1992-12-23 | 1996-08-15 | Neurosearch A/S | Alkyl substituted heterocyclic compounds |
AU690257B2 (en) * | 1994-04-19 | 1998-04-23 | Neurosearch A/S | Tropane-2-alcoxime derivatives as neurotransmitter reuptake inhibitors |
GB9626611D0 (en) * | 1996-12-20 | 1997-02-05 | Unilever Plc | Agglomerated silicas |
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1997
- 1997-02-21 UA UA98073814A patent/UA49872C2/uk unknown
- 1997-02-21 KR KR10-1998-0706518A patent/KR100446571B1/ko not_active IP Right Cessation
- 1997-02-21 DK DK97903355T patent/DK0885220T3/da active
- 1997-02-21 RU RU98117314/04A patent/RU2167876C2/ru active
- 1997-02-21 EP EP97903355A patent/EP0885220B1/en not_active Expired - Lifetime
- 1997-02-21 EP EP01108256A patent/EP1130020A1/en not_active Withdrawn
- 1997-02-21 TR TR1998/01641T patent/TR199801641T2/xx unknown
- 1997-02-21 HU HU9901199A patent/HU228356B1/hu not_active IP Right Cessation
- 1997-02-21 SG SG9903902A patent/SG99853A1/en unknown
- 1997-02-21 AT AT97903355T patent/ATE203023T1/de active
- 1997-02-21 US US09/101,524 patent/US6288079B1/en not_active Expired - Lifetime
- 1997-02-21 SI SI9730163T patent/SI0885220T1/xx unknown
- 1997-02-21 PT PT97903355T patent/PT885220E/pt unknown
- 1997-02-21 EE EE9800254A patent/EE04751B1/et not_active IP Right Cessation
- 1997-02-21 IL IL12514697A patent/IL125146A/en not_active IP Right Cessation
- 1997-02-21 SK SK929-98A patent/SK281813B6/sk not_active IP Right Cessation
- 1997-02-21 PL PL97328503A patent/PL185132B1/pl not_active IP Right Cessation
- 1997-02-21 DE DE69705608T patent/DE69705608T2/de not_active Expired - Lifetime
- 1997-02-21 AU AU17940/97A patent/AU720358B2/en not_active Ceased
- 1997-02-21 WO PCT/EP1997/000850 patent/WO1997030997A1/en active IP Right Grant
- 1997-02-21 CZ CZ19982520A patent/CZ287007B6/cs not_active IP Right Cessation
- 1997-02-21 ES ES97903355T patent/ES2159839T3/es not_active Expired - Lifetime
- 1997-02-21 ZA ZA9701525A patent/ZA971525B/xx unknown
- 1997-02-21 CN CN97192505A patent/CN1077574C/zh not_active Expired - Fee Related
- 1997-02-21 CA CA002244773A patent/CA2244773C/en not_active Expired - Lifetime
- 1997-02-21 BR BR9707636A patent/BR9707636A/pt not_active IP Right Cessation
- 1997-02-21 NZ NZ330886A patent/NZ330886A/xx not_active IP Right Cessation
- 1997-02-21 JP JP52981097A patent/JP3238414B2/ja not_active Expired - Fee Related
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1998
- 1998-07-15 BG BG102637A patent/BG63945B1/bg unknown
- 1998-08-17 IS IS4825A patent/IS1824B/is unknown
- 1998-08-21 NO NO19983877A patent/NO318731B1/no not_active IP Right Cessation
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1999
- 1999-09-17 HK HK99104015A patent/HK1018957A1/xx not_active IP Right Cessation
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2001
- 2001-03-21 US US09/814,413 patent/US6395748B2/en not_active Expired - Fee Related
- 2001-10-08 GR GR20010401690T patent/GR3036829T3/el unknown
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2002
- 2002-03-15 US US10/099,642 patent/US20020128284A1/en not_active Abandoned
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