SG40889G - 4-aryl-1,4-dihydropyridine-3,5-dicarboxylate derivatives - Google Patents
4-aryl-1,4-dihydropyridine-3,5-dicarboxylate derivativesInfo
- Publication number
- SG40889G SG40889G SG40889A SG40889A SG40889G SG 40889 G SG40889 G SG 40889G SG 40889 A SG40889 A SG 40889A SG 40889 A SG40889 A SG 40889A SG 40889 G SG40889 G SG 40889G
- Authority
- SG
- Singapore
- Prior art keywords
- dihydropyridine
- aryl
- dicarboxylate derivatives
- dicarboxylate
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B2205/00—Fibre drawing or extruding details
- C03B2205/44—Monotoring or regulating the preform feed rate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22383/84A IT1175620B (it) | 1984-08-22 | 1984-08-22 | Derivati piridinici |
IT21460/85A IT1187678B (it) | 1985-07-05 | 1985-07-05 | Procedimento di preparazione di derivati eterociclici |
Publications (1)
Publication Number | Publication Date |
---|---|
SG40889G true SG40889G (en) | 1989-12-22 |
Family
ID=26327905
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG40889A SG40889G (en) | 1984-08-22 | 1989-07-06 | 4-aryl-1,4-dihydropyridine-3,5-dicarboxylate derivatives |
Country Status (33)
Country | Link |
---|---|
US (2) | US4801599A (no) |
JP (2) | JPS6193162A (no) |
KR (1) | KR920004482B1 (no) |
AT (1) | AT394042B (no) |
AU (1) | AU578724B2 (no) |
BE (1) | BE903103A (no) |
BG (1) | BG60409B2 (no) |
CA (1) | CA1268180A (no) |
CH (1) | CH666684A5 (no) |
CS (1) | CS403091A3 (no) |
CY (1) | CY1494A (no) |
DE (1) | DE3529997C2 (no) |
DK (1) | DK165949C (no) |
ES (5) | ES8703839A1 (no) |
FI (1) | FI81568C (no) |
FR (1) | FR2569402B1 (no) |
GB (1) | GB2164336B (no) |
GR (1) | GR852016B (no) |
HK (1) | HK52990A (no) |
HU (1) | HU196754B (no) |
IE (1) | IE58486B1 (no) |
LU (2) | LU86047A1 (no) |
MX (1) | MX159974A (no) |
NL (2) | NL193065C (no) |
NO (2) | NO167142C (no) |
NZ (1) | NZ212895A (no) |
PH (1) | PH22014A (no) |
PT (1) | PT81000B (no) |
SA (1) | SA91120277B1 (no) |
SE (1) | SE459920B (no) |
SG (1) | SG40889G (no) |
SK (1) | SK278327B6 (no) |
ZW (1) | ZW13185A1 (no) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
ES2001104A6 (es) * | 1985-08-21 | 1988-04-16 | Glaxo Spa | Un procedimiento para la preparacion de nuevos derivados sustituidos del acido 1,4-dihidro-3,5-piridindicarboxilico. |
EP0226271B1 (en) * | 1985-08-21 | 1990-11-22 | GLAXO S.p.A. | 1,4-dihydropyridine compounds and their preparation and pharmaceutical formulation |
IT1204460B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1204462B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1204461B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1233370B (it) * | 1988-11-21 | 1992-03-27 | Glaxo Spa | Procedimento di preparazione di derivati diidropipiridinici utili nel trattamento di disturbi cardiovascolari |
US5102709A (en) | 1989-04-27 | 1992-04-07 | Canon Kabushiki Kaisha | Optical recording medium and process for production thereof |
US5196529A (en) * | 1990-10-09 | 1993-03-23 | Merck & Co., Inc. | 2-phenanthrenyl carbapenem intermediates |
US5177202A (en) * | 1990-10-09 | 1993-01-05 | Merck & Co., Inc. | 2-phenanthrenyl-carbapenems |
US5132421A (en) * | 1990-10-09 | 1992-07-21 | Merck & Co., Inc. | 2-naphthyl-carbapenem intermediates |
US5132422A (en) * | 1990-10-09 | 1992-07-21 | Merck & Co., Inc. | 2-naphthyl-carbapenem intermediates |
US5144028A (en) * | 1990-10-09 | 1992-09-01 | Merck & Co., Inc. | 2-(9-fluorenonyl)-carbapenem intermediates |
US5356889A (en) * | 1990-08-01 | 1994-10-18 | Merck & Co., Inc. | 2-(9-fluorenonyl)-carbapenem intermediates |
US5208329A (en) * | 1990-10-09 | 1993-05-04 | Merck & Co., Inc. | 2-biphenyl carbapenem intermediates |
IT1244728B (it) * | 1991-02-13 | 1994-08-08 | Glaxo Spa | Impiego medicamentoso di derivati diidropiridinici |
TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
WO2000027397A1 (en) * | 1998-11-06 | 2000-05-18 | Glaxo Group Limited | Antihypertensive medicaments containing lacidipine and telmisartan |
MXPA05001958A (es) | 2002-08-19 | 2005-04-28 | Pfizer Prod Inc | Terapia de combinacion para enfermedades hiperproliferativas. |
EA009646B1 (ru) * | 2003-05-30 | 2008-02-28 | Рэнбакси Лабораториз Лтд. | Замещённые производные пиррола и их применение в качестве ингибиторов hmg-coa |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
CN101090714A (zh) * | 2004-07-26 | 2007-12-19 | 康泽里克斯公司 | 通过吸入伊洛前列素和微粒制剂治疗肺动脉高血压症 |
WO2006113309A1 (en) | 2005-04-15 | 2006-10-26 | Dr. Reddy's Laboratories Ltd. | Lacidipine particles |
US20070043088A1 (en) * | 2005-08-16 | 2007-02-22 | Eswaraiah Sajja | Process for preparing lacidipine |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
ATE551059T1 (de) | 2005-10-26 | 2012-04-15 | Asahi Kasei Pharma Corp | Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie |
EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
AU2006313430B2 (en) * | 2005-11-08 | 2012-09-06 | Ranbaxy Laboratories Limited | Process for (3R,5R)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
TW200744583A (en) * | 2006-03-14 | 2007-12-16 | Ranbaxy Lab Ltd | Statin stabilizing dosage formulations |
MX2009000439A (es) * | 2006-07-14 | 2009-02-04 | Ranbaxy Lab Ltd | Formas polimorficas de un inhibidor de hmg-coa reductasa y usos de las mismas. |
US20080089947A1 (en) * | 2006-08-18 | 2008-04-17 | Knox Clayton D | Calcium Influx Inhibitors in the Treatment of Ischemia |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
WO2012037665A1 (en) | 2010-09-24 | 2012-03-29 | Oral Delivery Technology Ltd. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
PL2705839T3 (pl) | 2012-09-10 | 2018-07-31 | Rivopharm Sa | Farmaceutyczna kompozycja zawierająca lacydypinę i proces przygotowania |
CN105143203A (zh) | 2013-04-17 | 2015-12-09 | 辉瑞大药厂 | 用于治疗心血管疾病的n-哌啶-3-基苯甲酰胺衍生物 |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055B (zh) | 2019-01-18 | 2024-07-23 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3455945A (en) * | 1967-06-07 | 1969-07-15 | Smithkline Corp | 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines |
DE2228363A1 (de) * | 1972-06-10 | 1974-01-03 | Bayer Ag | 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
GB1409865A (en) * | 1973-02-13 | 1975-10-15 | Science Union & Cie | Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them |
US4307103A (en) * | 1978-09-08 | 1981-12-22 | Fujisawa Pharmaceutical Co., Ltd. | Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same |
DE3018259A1 (de) * | 1980-05-13 | 1981-11-19 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
-
1985
- 1985-07-29 NZ NZ212895A patent/NZ212895A/xx unknown
- 1985-08-20 SE SE8503888A patent/SE459920B/sv not_active IP Right Cessation
- 1985-08-20 GR GR852016A patent/GR852016B/el unknown
- 1985-08-20 ZW ZW131/85A patent/ZW13185A1/xx unknown
- 1985-08-20 NL NL8502296A patent/NL193065C/nl not_active IP Right Cessation
- 1985-08-20 DK DK378085A patent/DK165949C/da not_active IP Right Cessation
- 1985-08-20 US US06/767,593 patent/US4801599A/en not_active Expired - Lifetime
- 1985-08-21 FI FI853206A patent/FI81568C/fi not_active IP Right Cessation
- 1985-08-21 NO NO853293A patent/NO167142C/no not_active IP Right Cessation
- 1985-08-21 JP JP60181934A patent/JPS6193162A/ja active Granted
- 1985-08-21 MX MX206376A patent/MX159974A/es unknown
- 1985-08-21 LU LU86047A patent/LU86047A1/fr active Protection Beyond IP Right Term
- 1985-08-21 IE IE205485A patent/IE58486B1/en not_active IP Right Cessation
- 1985-08-21 CH CH3593/85A patent/CH666684A5/de not_active IP Right Cessation
- 1985-08-21 GB GB08520924A patent/GB2164336B/en not_active Expired
- 1985-08-21 LU LU88267C patent/LU88267I2/xx unknown
- 1985-08-21 CY CY1494A patent/CY1494A/xx unknown
- 1985-08-21 ES ES546324A patent/ES8703839A1/es not_active Expired
- 1985-08-22 KR KR1019850006044A patent/KR920004482B1/ko not_active IP Right Cessation
- 1985-08-22 AU AU46576/85A patent/AU578724B2/en not_active Expired
- 1985-08-22 DE DE3529997A patent/DE3529997C2/de not_active Expired - Lifetime
- 1985-08-22 BE BE0/215493A patent/BE903103A/fr not_active IP Right Cessation
- 1985-08-22 HU HU853202A patent/HU196754B/hu unknown
- 1985-08-22 PT PT81000A patent/PT81000B/pt unknown
- 1985-08-22 AT AT0245485A patent/AT394042B/de not_active IP Right Cessation
- 1985-08-22 CA CA000489261A patent/CA1268180A/en not_active Expired - Lifetime
- 1985-08-22 PH PH32680A patent/PH22014A/en unknown
- 1985-08-22 FR FR8512631A patent/FR2569402B1/fr not_active Expired
-
1986
- 1986-02-14 ES ES552048A patent/ES8707931A1/es not_active Expired
- 1986-02-14 ES ES552051A patent/ES8707932A1/es not_active Expired
- 1986-02-14 ES ES552050A patent/ES8707930A1/es not_active Expired
- 1986-02-14 ES ES552049A patent/ES8802497A1/es not_active Expired
-
1988
- 1988-07-27 JP JP63185661A patent/JPH0686430B2/ja not_active Expired - Lifetime
-
1989
- 1989-01-23 US US07/300,022 patent/US5011848A/en not_active Expired - Lifetime
- 1989-07-06 SG SG40889A patent/SG40889G/en unknown
-
1990
- 1990-07-12 HK HK529/90A patent/HK52990A/xx not_active IP Right Cessation
-
1991
- 1991-12-16 SA SA91120277A patent/SA91120277B1/ar unknown
- 1991-12-23 SK SK4030-91A patent/SK278327B6/sk unknown
- 1991-12-23 CS CS914030A patent/CS403091A3/cs unknown
-
1993
- 1993-08-20 BG BG98061A patent/BG60409B2/bg unknown
-
1998
- 1998-11-27 NL NL980037C patent/NL980037I2/nl unknown
-
1999
- 1999-04-23 NO NO1999007C patent/NO1999007I1/no unknown
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