ES552049A0 - Un procedimiento para la preparacion de esteres del acido 1,4-dihidro -3,5-piridindi-carboxilico. - Google Patents
Un procedimiento para la preparacion de esteres del acido 1,4-dihidro -3,5-piridindi-carboxilico.Info
- Publication number
- ES552049A0 ES552049A0 ES552049A ES552049A ES552049A0 ES 552049 A0 ES552049 A0 ES 552049A0 ES 552049 A ES552049 A ES 552049A ES 552049 A ES552049 A ES 552049A ES 552049 A0 ES552049 A0 ES 552049A0
- Authority
- ES
- Spain
- Prior art keywords
- piridindi
- carboxilico
- dihidro
- esters
- procedure
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
- C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C03—GLASS; MINERAL OR SLAG WOOL
- C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
- C03B2205/00—Fibre drawing or extruding details
- C03B2205/44—Monotoring or regulating the preform feed rate
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT22383/84A IT1175620B (it) | 1984-08-22 | 1984-08-22 | Derivati piridinici |
IT21460/85A IT1187678B (it) | 1985-07-05 | 1985-07-05 | Procedimento di preparazione di derivati eterociclici |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8802497A1 ES8802497A1 (es) | 1988-07-01 |
ES552049A0 true ES552049A0 (es) | 1988-07-01 |
Family
ID=26327905
Family Applications (5)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES546324A Expired ES8703839A1 (es) | 1984-08-22 | 1985-08-21 | Un procedimiento para la preparacion de esteres de acidos 1,4-dihidro-3,5-piridin-dicarbaxolicos. |
ES552051A Expired ES8707932A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4-dihidro-3,5, piridincarboxilico. |
ES552048A Expired ES8707931A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4, dihidro-3,5-piridincarboxilico. |
ES552049A Expired ES8802497A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4-dihidro -3,5-piridindi-carboxilico. |
ES552050A Expired ES8707930A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4-dihidro-3, 5, piridincarboxilico. |
Family Applications Before (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES546324A Expired ES8703839A1 (es) | 1984-08-22 | 1985-08-21 | Un procedimiento para la preparacion de esteres de acidos 1,4-dihidro-3,5-piridin-dicarbaxolicos. |
ES552051A Expired ES8707932A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4-dihidro-3,5, piridincarboxilico. |
ES552048A Expired ES8707931A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4, dihidro-3,5-piridincarboxilico. |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES552050A Expired ES8707930A1 (es) | 1984-08-22 | 1986-02-14 | Un procedimiento para la preparacion de esteres del acido 1,4-dihidro-3, 5, piridincarboxilico. |
Country Status (33)
Country | Link |
---|---|
US (2) | US4801599A (es) |
JP (2) | JPS6193162A (es) |
KR (1) | KR920004482B1 (es) |
AT (1) | AT394042B (es) |
AU (1) | AU578724B2 (es) |
BE (1) | BE903103A (es) |
BG (1) | BG60409B2 (es) |
CA (1) | CA1268180A (es) |
CH (1) | CH666684A5 (es) |
CS (1) | CS403091A3 (es) |
CY (1) | CY1494A (es) |
DE (1) | DE3529997C2 (es) |
DK (1) | DK165949C (es) |
ES (5) | ES8703839A1 (es) |
FI (1) | FI81568C (es) |
FR (1) | FR2569402B1 (es) |
GB (1) | GB2164336B (es) |
GR (1) | GR852016B (es) |
HK (1) | HK52990A (es) |
HU (1) | HU196754B (es) |
IE (1) | IE58486B1 (es) |
LU (2) | LU86047A1 (es) |
MX (1) | MX159974A (es) |
NL (2) | NL193065C (es) |
NO (2) | NO167142C (es) |
NZ (1) | NZ212895A (es) |
PH (1) | PH22014A (es) |
PT (1) | PT81000B (es) |
SA (1) | SA91120277B1 (es) |
SE (1) | SE459920B (es) |
SG (1) | SG40889G (es) |
SK (1) | SK278327B6 (es) |
ZW (1) | ZW13185A1 (es) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
EP0226271B1 (en) * | 1985-08-21 | 1990-11-22 | GLAXO S.p.A. | 1,4-dihydropyridine compounds and their preparation and pharmaceutical formulation |
ES2001104A6 (es) * | 1985-08-21 | 1988-04-16 | Glaxo Spa | Un procedimiento para la preparacion de nuevos derivados sustituidos del acido 1,4-dihidro-3,5-piridindicarboxilico. |
IT1204460B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1204461B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1204462B (it) * | 1986-02-20 | 1989-03-01 | Glaxo Spa | Derivati eterociclici |
IT1233370B (it) * | 1988-11-21 | 1992-03-27 | Glaxo Spa | Procedimento di preparazione di derivati diidropipiridinici utili nel trattamento di disturbi cardiovascolari |
EP0395369B1 (en) | 1989-04-27 | 1997-07-02 | Canon Inc. | Optical recording medium and process for production thereof |
US5177202A (en) * | 1990-10-09 | 1993-01-05 | Merck & Co., Inc. | 2-phenanthrenyl-carbapenems |
US5196529A (en) * | 1990-10-09 | 1993-03-23 | Merck & Co., Inc. | 2-phenanthrenyl carbapenem intermediates |
US5132421A (en) * | 1990-10-09 | 1992-07-21 | Merck & Co., Inc. | 2-naphthyl-carbapenem intermediates |
US5132422A (en) * | 1990-10-09 | 1992-07-21 | Merck & Co., Inc. | 2-naphthyl-carbapenem intermediates |
US5144028A (en) * | 1990-10-09 | 1992-09-01 | Merck & Co., Inc. | 2-(9-fluorenonyl)-carbapenem intermediates |
US5356889A (en) * | 1990-08-01 | 1994-10-18 | Merck & Co., Inc. | 2-(9-fluorenonyl)-carbapenem intermediates |
US5208329A (en) * | 1990-10-09 | 1993-05-04 | Merck & Co., Inc. | 2-biphenyl carbapenem intermediates |
IT1244728B (it) * | 1991-02-13 | 1994-08-08 | Glaxo Spa | Impiego medicamentoso di derivati diidropiridinici |
TW483763B (en) * | 1994-09-02 | 2002-04-21 | Astra Ab | Pharmaceutical composition comprising of ramipril and dihydropyridine compound |
AU1042199A (en) * | 1998-11-06 | 2000-05-29 | Boehringer Ingelheim International Gmbh | Antihypertensive medicaments containing lacidipine and telmisartan |
CN1681495B (zh) | 2002-08-19 | 2010-05-12 | 辉瑞产品公司 | 用于治疗过度增生性疾病的组合物 |
WO2004106299A2 (en) * | 2003-05-30 | 2004-12-09 | Ranbaxy Laboratories Limited | Substituted pyrrole derivatives and their use as hmg-co inhibitors |
US20050037063A1 (en) * | 2003-07-21 | 2005-02-17 | Bolton Anthony E. | Combined therapies |
BRPI0513866A (pt) * | 2004-07-26 | 2008-05-20 | Cotherix Inc | composição, micropartìculas, método para o tratamento da hipertensão pulmonar, e dispositivo de inalação |
WO2006113309A1 (en) | 2005-04-15 | 2006-10-26 | Dr. Reddy's Laboratories Ltd. | Lacidipine particles |
US20070043088A1 (en) * | 2005-08-16 | 2007-02-22 | Eswaraiah Sajja | Process for preparing lacidipine |
US7741317B2 (en) | 2005-10-21 | 2010-06-22 | Bristol-Myers Squibb Company | LXR modulators |
EP2351569B1 (en) | 2005-10-26 | 2012-08-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
US7893050B2 (en) * | 2005-10-26 | 2011-02-22 | Asahi Kasei Pharma Corporation | Fasudil in combination therapies for the treatment of pulmonary arterial hypertension |
KR101329112B1 (ko) * | 2005-11-08 | 2013-11-14 | 랜박시 래보러터리스 리미티드 | (3r,5r)-7-〔2-(4-플루오로페닐)-5-이소프로필-3-페닐-4-〔(4-히드록시 메틸 페닐 아미노)카르보닐〕-피롤-1-일〕-3,5-디히드록시 헵탄산 헤미 칼슘염의 제조 방법 |
US7888376B2 (en) | 2005-11-23 | 2011-02-15 | Bristol-Myers Squibb Company | Heterocyclic CETP inhibitors |
US7919506B2 (en) | 2006-03-10 | 2011-04-05 | Pfizer Inc. | Dibenzyl amine compounds and derivatives |
WO2008020314A2 (en) * | 2006-03-14 | 2008-02-21 | Ranbaxy Laboratories Limited | Statin stabilizing dosage formulations |
MX2009000439A (es) * | 2006-07-14 | 2009-02-04 | Ranbaxy Lab Ltd | Formas polimorficas de un inhibidor de hmg-coa reductasa y usos de las mismas. |
US20080089947A1 (en) * | 2006-08-18 | 2008-04-17 | Knox Clayton D | Calcium Influx Inhibitors in the Treatment of Ischemia |
CN101663262B (zh) | 2006-12-01 | 2014-03-26 | 百时美施贵宝公司 | 用于治疗动脉粥样硬化和心血管疾病的作为cetp抑制剂的n-(3-苄基)-2,2-(二苯基)-丙-1胺衍生物 |
US8883844B2 (en) | 2010-09-24 | 2014-11-11 | Nitrogenix Inc. | Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions |
PL2705839T3 (pl) | 2012-09-10 | 2018-07-31 | Rivopharm Sa | Farmaceutyczna kompozycja zawierająca lacydypinę i proces przygotowania |
WO2014170786A1 (en) | 2013-04-17 | 2014-10-23 | Pfizer Inc. | N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases |
WO2016055901A1 (en) | 2014-10-08 | 2016-04-14 | Pfizer Inc. | Substituted amide compounds |
CN113574055A (zh) | 2019-01-18 | 2021-10-29 | 阿斯利康(瑞典)有限公司 | Pcsk9抑制剂及其使用方法 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3455945A (en) * | 1967-06-07 | 1969-07-15 | Smithkline Corp | 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines |
DE2228363A1 (de) * | 1972-06-10 | 1974-01-03 | Bayer Ag | 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel |
GB1409865A (en) * | 1973-02-13 | 1975-10-15 | Science Union & Cie | Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them |
US4307103A (en) * | 1978-09-08 | 1981-12-22 | Fujisawa Pharmaceutical Co., Ltd. | Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same |
DE3018259A1 (de) * | 1980-05-13 | 1981-11-19 | Bayer Ag, 5090 Leverkusen | 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln |
NZ201395A (en) * | 1981-07-30 | 1987-02-20 | Bayer Ag | Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines |
DE3207982A1 (de) * | 1982-03-05 | 1983-09-08 | Bayer Ag, 5090 Leverkusen | Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln |
NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
-
1985
- 1985-07-29 NZ NZ212895A patent/NZ212895A/xx unknown
- 1985-08-20 DK DK378085A patent/DK165949C/da not_active IP Right Cessation
- 1985-08-20 US US06/767,593 patent/US4801599A/en not_active Expired - Lifetime
- 1985-08-20 GR GR852016A patent/GR852016B/el unknown
- 1985-08-20 ZW ZW131/85A patent/ZW13185A1/xx unknown
- 1985-08-20 NL NL8502296A patent/NL193065C/nl not_active IP Right Cessation
- 1985-08-20 SE SE8503888A patent/SE459920B/sv not_active IP Right Cessation
- 1985-08-21 ES ES546324A patent/ES8703839A1/es not_active Expired
- 1985-08-21 JP JP60181934A patent/JPS6193162A/ja active Granted
- 1985-08-21 GB GB08520924A patent/GB2164336B/en not_active Expired
- 1985-08-21 MX MX206376A patent/MX159974A/es unknown
- 1985-08-21 NO NO853293A patent/NO167142C/no not_active IP Right Cessation
- 1985-08-21 FI FI853206A patent/FI81568C/fi not_active IP Right Cessation
- 1985-08-21 CY CY1494A patent/CY1494A/xx unknown
- 1985-08-21 CH CH3593/85A patent/CH666684A5/de not_active IP Right Cessation
- 1985-08-21 LU LU86047A patent/LU86047A1/fr active Protection Beyond IP Right Term
- 1985-08-21 LU LU88267C patent/LU88267I2/xx unknown
- 1985-08-21 IE IE205485A patent/IE58486B1/en not_active IP Right Cessation
- 1985-08-22 PT PT81000A patent/PT81000B/pt unknown
- 1985-08-22 FR FR8512631A patent/FR2569402B1/fr not_active Expired
- 1985-08-22 CA CA000489261A patent/CA1268180A/en not_active Expired - Lifetime
- 1985-08-22 AU AU46576/85A patent/AU578724B2/en not_active Expired
- 1985-08-22 DE DE3529997A patent/DE3529997C2/de not_active Expired - Lifetime
- 1985-08-22 AT AT0245485A patent/AT394042B/de not_active IP Right Cessation
- 1985-08-22 HU HU853202A patent/HU196754B/hu unknown
- 1985-08-22 BE BE0/215493A patent/BE903103A/fr not_active IP Right Cessation
- 1985-08-22 KR KR1019850006044A patent/KR920004482B1/ko not_active IP Right Cessation
- 1985-08-22 PH PH32680A patent/PH22014A/en unknown
-
1986
- 1986-02-14 ES ES552051A patent/ES8707932A1/es not_active Expired
- 1986-02-14 ES ES552048A patent/ES8707931A1/es not_active Expired
- 1986-02-14 ES ES552049A patent/ES8802497A1/es not_active Expired
- 1986-02-14 ES ES552050A patent/ES8707930A1/es not_active Expired
-
1988
- 1988-07-27 JP JP63185661A patent/JPH0686430B2/ja not_active Expired - Lifetime
-
1989
- 1989-01-23 US US07/300,022 patent/US5011848A/en not_active Expired - Lifetime
- 1989-07-06 SG SG40889A patent/SG40889G/en unknown
-
1990
- 1990-07-12 HK HK529/90A patent/HK52990A/xx not_active IP Right Cessation
-
1991
- 1991-12-16 SA SA91120277A patent/SA91120277B1/ar unknown
- 1991-12-23 SK SK4030-91A patent/SK278327B6/sk unknown
- 1991-12-23 CS CS914030A patent/CS403091A3/cs unknown
-
1993
- 1993-08-20 BG BG98061A patent/BG60409B2/bg unknown
-
1998
- 1998-11-27 NL NL980037C patent/NL980037I2/nl unknown
-
1999
- 1999-04-23 NO NO1999007C patent/NO1999007I1/no unknown
Also Published As
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20080416 |