FI853206L - Heterocykliska derivat. - Google Patents

Heterocykliska derivat.

Info

Publication number
FI853206L
FI853206L FI853206A FI853206A FI853206L FI 853206 L FI853206 L FI 853206L FI 853206 A FI853206 A FI 853206A FI 853206 A FI853206 A FI 853206A FI 853206 L FI853206 L FI 853206L
Authority
FI
Finland
Prior art keywords
heterocyclis
derivatives
heterocyclis derivatives
Prior art date
Application number
FI853206A
Other languages
English (en)
Other versions
FI81568C (fi
FI81568B (fi
FI853206A0 (fi
Inventor
Claudio Semeraro
Dino Micheli
Daniele Pieraccioli
Giovanni Gaviraghi
Allan David Borthwick
Original Assignee
Glaxo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT22383/84A external-priority patent/IT1175620B/it
Priority claimed from IT21460/85A external-priority patent/IT1187678B/it
Application filed by Glaxo Spa filed Critical Glaxo Spa
Publication of FI853206A0 publication Critical patent/FI853206A0/fi
Publication of FI853206L publication Critical patent/FI853206L/fi
Application granted granted Critical
Publication of FI81568B publication Critical patent/FI81568B/fi
Publication of FI81568C publication Critical patent/FI81568C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/80—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D211/84—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen directly attached to ring carbon atoms
    • C07D211/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C03—GLASS; MINERAL OR SLAG WOOL
    • C03B—MANUFACTURE, SHAPING, OR SUPPLEMENTARY PROCESSES
    • C03B2205/00—Fibre drawing or extruding details
    • C03B2205/44—Monotoring or regulating the preform feed rate

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI853206A 1984-08-22 1985-08-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,4-dihydropyridinderivat. FI81568C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
IT2238384 1984-08-22
IT22383/84A IT1175620B (it) 1984-08-22 1984-08-22 Derivati piridinici
IT2146085 1985-07-05
IT21460/85A IT1187678B (it) 1985-07-05 1985-07-05 Procedimento di preparazione di derivati eterociclici

Publications (4)

Publication Number Publication Date
FI853206A0 FI853206A0 (fi) 1985-08-21
FI853206L true FI853206L (fi) 1986-02-23
FI81568B FI81568B (fi) 1990-07-31
FI81568C FI81568C (fi) 1990-11-12

Family

ID=26327905

Family Applications (1)

Application Number Title Priority Date Filing Date
FI853206A FI81568C (fi) 1984-08-22 1985-08-21 Foerfarande foer framstaellning av terapeutiskt anvaendbara 1,4-dihydropyridinderivat.

Country Status (33)

Country Link
US (2) US4801599A (fi)
JP (2) JPS6193162A (fi)
KR (1) KR920004482B1 (fi)
AT (1) AT394042B (fi)
AU (1) AU578724B2 (fi)
BE (1) BE903103A (fi)
BG (1) BG60409B2 (fi)
CA (1) CA1268180A (fi)
CH (1) CH666684A5 (fi)
CS (1) CS403091A3 (fi)
CY (1) CY1494A (fi)
DE (1) DE3529997C2 (fi)
DK (1) DK165949C (fi)
ES (5) ES8703839A1 (fi)
FI (1) FI81568C (fi)
FR (1) FR2569402B1 (fi)
GB (1) GB2164336B (fi)
GR (1) GR852016B (fi)
HK (1) HK52990A (fi)
HU (1) HU196754B (fi)
IE (1) IE58486B1 (fi)
LU (2) LU86047A1 (fi)
MX (1) MX159974A (fi)
NL (2) NL193065C (fi)
NO (2) NO167142C (fi)
NZ (1) NZ212895A (fi)
PH (1) PH22014A (fi)
PT (1) PT81000B (fi)
SA (1) SA91120277B1 (fi)
SE (1) SE459920B (fi)
SG (1) SG40889G (fi)
SK (1) SK278327B6 (fi)
ZW (1) ZW13185A1 (fi)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
DE3675747D1 (de) * 1985-08-21 1991-01-03 Glaxo Spa 1,4-dihydropyridinverbindungen und ihre herstellung und pharmazeutische formulierung.
DK397686A (da) * 1985-08-21 1987-02-22 Glaxo Spa Heterocycliske forbindelser
IT1204462B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204460B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1204461B (it) * 1986-02-20 1989-03-01 Glaxo Spa Derivati eterociclici
IT1233370B (it) * 1988-11-21 1992-03-27 Glaxo Spa Procedimento di preparazione di derivati diidropipiridinici utili nel trattamento di disturbi cardiovascolari
EP0395369B1 (en) 1989-04-27 1997-07-02 Canon Inc. Optical recording medium and process for production thereof
US5196529A (en) * 1990-10-09 1993-03-23 Merck & Co., Inc. 2-phenanthrenyl carbapenem intermediates
US5177202A (en) * 1990-10-09 1993-01-05 Merck & Co., Inc. 2-phenanthrenyl-carbapenems
US5132422A (en) * 1990-10-09 1992-07-21 Merck & Co., Inc. 2-naphthyl-carbapenem intermediates
US5132421A (en) * 1990-10-09 1992-07-21 Merck & Co., Inc. 2-naphthyl-carbapenem intermediates
US5356889A (en) * 1990-08-01 1994-10-18 Merck & Co., Inc. 2-(9-fluorenonyl)-carbapenem intermediates
US5144028A (en) * 1990-10-09 1992-09-01 Merck & Co., Inc. 2-(9-fluorenonyl)-carbapenem intermediates
US5208329A (en) * 1990-10-09 1993-05-04 Merck & Co., Inc. 2-biphenyl carbapenem intermediates
IT1244728B (it) * 1991-02-13 1994-08-08 Glaxo Spa Impiego medicamentoso di derivati diidropiridinici
TW483763B (en) * 1994-09-02 2002-04-21 Astra Ab Pharmaceutical composition comprising of ramipril and dihydropyridine compound
WO2000027397A1 (en) * 1998-11-06 2000-05-18 Glaxo Group Limited Antihypertensive medicaments containing lacidipine and telmisartan
BR0313593A (pt) 2002-08-19 2005-07-12 Pfizer Prod Inc Terapia de combinação para doenças hiperproliferativas
JP4901474B2 (ja) * 2003-05-30 2012-03-21 ランバクシー ラボラトリーズ リミテッド 置換ピロール誘導体
US20050037063A1 (en) * 2003-07-21 2005-02-17 Bolton Anthony E. Combined therapies
US20060147520A1 (en) * 2004-07-26 2006-07-06 Curtis Ruegg Treatment of pulmonary hypertension by inhaled iloprost with a microparticle formulation
WO2006113309A1 (en) 2005-04-15 2006-10-26 Dr. Reddy's Laboratories Ltd. Lacidipine particles
US20070043088A1 (en) * 2005-08-16 2007-02-22 Eswaraiah Sajja Process for preparing lacidipine
US7741317B2 (en) 2005-10-21 2010-06-22 Bristol-Myers Squibb Company LXR modulators
ATE551059T1 (de) 2005-10-26 2012-04-15 Asahi Kasei Pharma Corp Fasudil in kombination mit bosentan zur behandlung von pulmonaler arterieller hypertonie
EP2351569B1 (en) 2005-10-26 2012-08-22 Asahi Kasei Pharma Corporation Fasudil in combination therapies for the treatment of pulmonary arterial hypertension
SG166829A1 (en) * 2005-11-08 2010-12-29 Ranbaxy Lab Ltd Process for (3r, 5r)-7-[2-(4-fluorophenyl)-5-isopropyl-3-phenyl-4- [(4-hydroxy methyl phenyl amino) carbonyl]-pyrrol-1-yl]-3, 5-dihydroxy-heptanoic acid hemi calcium salt
US7888376B2 (en) 2005-11-23 2011-02-15 Bristol-Myers Squibb Company Heterocyclic CETP inhibitors
US7919506B2 (en) 2006-03-10 2011-04-05 Pfizer Inc. Dibenzyl amine compounds and derivatives
CL2007000667A1 (es) * 2006-03-14 2008-03-14 Ranbaxi Lab Ltd Composicion farmaceutica que comprende al acido 7-[2-(4-fluorofenil)-5-isopropil-3-fenil-4-[(4-hidroximetilfenilamino)carbonil]pirrol-1-il]-3,5-dihidroxi-heptanoico o una sal y al menos un agente estabilizante; procedimiento de preparacion, util en e
EP2049102A4 (en) * 2006-07-14 2010-12-22 Ranbaxy Lab Ltd POLYMORPHIC FORMS OF AN HMG COA REDUCTASE HEATHER AND USE
US20080089947A1 (en) * 2006-08-18 2008-04-17 Knox Clayton D Calcium Influx Inhibitors in the Treatment of Ischemia
EP2094643B1 (en) 2006-12-01 2012-02-29 Bristol-Myers Squibb Company N-((3-benzyl)-2,2-(bis-phenyl)-propan-1-amine derivatives as cetp inhibitors for the treatment of atherosclerosis and cardiovascular diseases
US8883844B2 (en) 2010-09-24 2014-11-11 Nitrogenix Inc. Nitric oxide releasing amino acid ester for treatment of pulmonary hypertension and other respiratory conditions
ITMI20131485A1 (it) 2012-09-10 2014-03-11 Rivopharm Sa Composizione farmaceutica comprendente lacipidina e processo di preparazione
EP2986599A1 (en) 2013-04-17 2016-02-24 Pfizer Inc. N-piperidin-3-ylbenzamide derivatives for treating cardiovascular diseases
WO2016055901A1 (en) 2014-10-08 2016-04-14 Pfizer Inc. Substituted amide compounds
CA3125765A1 (en) 2019-01-18 2020-07-23 Astrazeneca Ab Pcsk9 inhibitors and methods of use thereof

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3455945A (en) * 1967-06-07 1969-07-15 Smithkline Corp 4-(carboxy (and carbo-lower alkoxy)phenyl)-1,4-dihydropyridines
DE2228363A1 (de) * 1972-06-10 1974-01-03 Bayer Ag 1,4-dihydropyridine, verfahren zu ihrer herstellung sowie ihre verwendung als arzneimittel
GB1409865A (en) * 1973-02-13 1975-10-15 Science Union & Cie Dihydropyridines derivatives their preparation and pharmaceu tical compositions containing them
US4307103A (en) * 1978-09-08 1981-12-22 Fujisawa Pharmaceutical Co., Ltd. Dihydropyridine derivative, processes for preparation thereof and pharmaceutical composition comprising the same
DE3018259A1 (de) * 1980-05-13 1981-11-19 Bayer Ag, 5090 Leverkusen 1,4-dihydropyridine mit unterschiedlichen substituenten in 2- und 6-position, verfahren zu ihrer herstellung und ihre verwendung in arzneimitteln
NZ201395A (en) * 1981-07-30 1987-02-20 Bayer Ag Pharmaceutical compositions containing 1,4-dihydropyridines and certain of these dihydropyridines
DE3207982A1 (de) * 1982-03-05 1983-09-08 Bayer Ag, 5090 Leverkusen Neue 1,4-dihydropyridine, verfahren zu ihrer herstellung und ihrer verwendung in arzneimitteln
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions

Also Published As

Publication number Publication date
GB2164336B (en) 1988-06-08
DE3529997A1 (de) 1986-03-06
ES8703839A1 (es) 1987-03-01
ZW13185A1 (en) 1986-03-19
NO853293L (no) 1986-02-24
NL193065B (nl) 1998-05-06
NL193065C (nl) 1998-09-08
SE8503888D0 (sv) 1985-08-20
JPS6193162A (ja) 1986-05-12
HU196754B (en) 1989-01-30
ES552051A0 (es) 1987-09-01
DE3529997C2 (de) 1996-01-18
PH22014A (en) 1988-05-02
US5011848A (en) 1991-04-30
GB8520924D0 (en) 1985-09-25
LU88267I2 (fi) 1994-02-03
SE8503888L (sv) 1986-02-23
NL980037I1 (nl) 1999-02-01
ES552049A0 (es) 1988-07-01
CS403091A3 (en) 1992-06-17
IE58486B1 (en) 1993-09-22
NL8502296A (nl) 1986-03-17
CY1494A (en) 1990-02-16
NL980037I2 (nl) 1999-03-01
LU86047A1 (fr) 1986-02-28
FR2569402B1 (fr) 1989-09-22
KR870002073A (ko) 1987-03-28
FI81568C (fi) 1990-11-12
SK278327B6 (en) 1996-11-06
CH666684A5 (de) 1988-08-15
SG40889G (en) 1989-12-22
JPS6479152A (en) 1989-03-24
CA1268180A (en) 1990-04-24
PT81000B (pt) 1988-03-03
KR920004482B1 (ko) 1992-06-05
ES552048A0 (es) 1987-09-01
PT81000A (en) 1985-09-01
DK378085A (da) 1986-02-23
NO167142C (no) 1991-10-09
BE903103A (fr) 1986-02-24
NO167142B (no) 1991-07-01
DK165949B (da) 1993-02-15
ES8707930A1 (es) 1987-09-01
FI81568B (fi) 1990-07-31
ES552050A0 (es) 1987-09-01
ES8802497A1 (es) 1988-07-01
AU578724B2 (en) 1988-11-03
GB2164336A (en) 1986-03-19
ES546324A0 (es) 1987-03-01
US4801599A (en) 1989-01-31
FR2569402A1 (fr) 1986-02-28
HK52990A (en) 1990-07-20
DK378085D0 (da) 1985-08-20
ES8707931A1 (es) 1987-09-01
MX159974A (es) 1989-10-17
JPH0686430B2 (ja) 1994-11-02
NZ212895A (en) 1988-07-28
FI853206A0 (fi) 1985-08-21
SE459920B (sv) 1989-08-21
JPH0550506B2 (fi) 1993-07-29
BG60409B2 (bg) 1995-02-28
ATA245485A (de) 1991-07-15
IE852054L (en) 1986-02-22
AU4657685A (en) 1986-02-27
HUT40625A (en) 1987-01-28
SA91120277B1 (ar) 2006-05-15
AT394042B (de) 1992-01-27
ES8707932A1 (es) 1987-09-01
DK165949C (da) 1993-07-05
NO1999007I1 (no) 1999-04-23
GR852016B (fi) 1985-12-19

Similar Documents

Publication Publication Date Title
FI853206A0 (fi) Heterocykliska derivat.
DE3580134D1 (de) Benzoesaeurederivate.
DE3581051D1 (de) Substituierte azolylmethyl-cyclopropyl-carbinol-derivate.
DE3585671D1 (de) 5-amino-4-hydroxyvalerylamid-derivate.
DE3579625D1 (de) Aminoalkylphenoxyderivate.
MX9203043A (es) Derivados de piridina.
FI896014A0 (fi) Heterocykliska derivat.
FI851738L (fi) Foerhandsupptagningssystem av en order foer villkorlig hoppinstruktion i en centralprocessorenhet.
FI842211A0 (fi) Kefalosporin derivat.
FI852964L (fi) Foerfarande foer framstaellning av 3-substituerade derivat av 1-amino-2-hydroxipropan.
FI860622A0 (fi) Heterocykliska derivat.
FI820882L (fi) Heterocykliska derivat
ATE32711T1 (de) Fluorallylaminderivate.
DE3583726D1 (de) 5-fluoruracilderivate.
DE3482590D1 (de) Carboxyalkyl-peptid-derivate.
NO853435L (no) Substituerte 7-oksomitosaner.
FI852064L (fi) Cykloalkan-inden-karboxi -imidamidderivat.
FI851520A0 (fi) Anordning foer sammanpressning av en blaosfolieslang.
FI860929A0 (fi) Foerfarande foer framstaellning av tricykliskt dibenzo-kondenserade derivat.
FI851444L (fi) Kefalosporin derivat och salter daerav.
ATE36330T1 (de) Eburnanderivate.
NO892643L (no) Substituerte azacykloheksyl-derivater.
FI853718A0 (fi) Foerfarande foer framstaellning av derivat av difenylazometiner med omaettad kolvaetekedja.
IT8523063A0 (it) Mezzi fungicidi-selettivi.
ATE37550T1 (de) 9a-aza-9a-homoerythromycin-derivate.

Legal Events

Date Code Title Description
FG Patent granted

Owner name: GLAXO S.P.A.

MA Patent expired