IT1244728B - Impiego medicamentoso di derivati diidropiridinici - Google Patents
Impiego medicamentoso di derivati diidropiridiniciInfo
- Publication number
- IT1244728B IT1244728B ITMI910359A ITMI910359A IT1244728B IT 1244728 B IT1244728 B IT 1244728B IT MI910359 A ITMI910359 A IT MI910359A IT MI910359 A ITMI910359 A IT MI910359A IT 1244728 B IT1244728 B IT 1244728B
- Authority
- IT
- Italy
- Prior art keywords
- medical use
- dihydropyridine derivatives
- preparation
- drugs
- pyridinbicarboxylic
- Prior art date
Links
- YNGDWRXWKFWCJY-UHFFFAOYSA-N 1,4-Dihydropyridine Chemical class C1C=CNC=C1 YNGDWRXWKFWCJY-UHFFFAOYSA-N 0.000 title 1
- 229940085304 dihydropyridine derivative selective calcium channel blockers with mainly vascular effects Drugs 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 2
- 229940079593 drug Drugs 0.000 abstract 2
- 206010003210 Arteriosclerosis Diseases 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 208000024172 Cardiovascular disease Diseases 0.000 abstract 1
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 208000011775 arteriosclerosis disease Diseases 0.000 abstract 1
- 125000004925 dihydropyridyl group Chemical class N1(CC=CC=C1)* 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000002969 morbid Effects 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicinal Preparation (AREA)
Abstract
Un derivato diidropiridinico è utilizzato, in miscela con eccipienti o veicoli di uso farmaceutico, nella preparazione di farmaci attivi contro disturbi cardiovascolari. In particolare è descritto l'uso dell'estere dietilico dell'acido (E) -4-[2[3-(1, 1-dimetiletossi)-3-osso-1-propenil]fenil]-1, 4-diidro-2, 6-dimetil-3, 5-piridinbicarbossilico nella preparazione di farmaci utili nella prevenzione e nel trattamento dell'aterosclerosi e dell'arteriosclerosi, nonché di forme morbose ad esse associate.
Priority Applications (25)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI910359A IT1244728B (it) | 1991-02-13 | 1991-02-13 | Impiego medicamentoso di derivati diidropiridinici |
| US08/094,150 US5455257A (en) | 1991-02-13 | 1992-02-08 | Lacidipine for the treatment of arteriosclerosis |
| DE69221649T DE69221649T2 (de) | 1991-02-13 | 1992-02-08 | Lacidipin zur Behandlung der Arteriosklerosis |
| EP92102146A EP0499920B1 (en) | 1991-02-13 | 1992-02-08 | Lacidipine for the treatment of arteriosclerosis |
| EP92903946A EP0576433A1 (en) | 1991-02-13 | 1992-02-08 | Use of lacidipine for the treatment of arteriosclerosis |
| ES92102146T ES2106098T3 (es) | 1991-02-13 | 1992-02-08 | Lacidipino para el tratamiento de la arteriosclerosis. |
| RU93054780A RU2136279C1 (ru) | 1991-02-13 | 1992-02-08 | Применение лацидипина для лечения артериосклероза |
| DK92102146.5T DK0499920T3 (da) | 1991-02-13 | 1992-02-08 | Lacidipin til behandling af arteriosclerosis |
| PCT/EP1992/000276 WO1992014460A1 (en) | 1991-02-13 | 1992-02-08 | Use of lacidipine for the treatment of arteriosclerosis |
| CS931650A CZ281760B6 (cs) | 1991-02-13 | 1992-02-08 | Použití diethylesteru kyseliny (E)-4-/2-/3-(1,1-dimethylethosy)-3-oxo-1-propenyl/fenyl/-1,4-dihydr o-2,6-dimethyl-3,5-pyridindikarboxylové pro výrobu farmaceutických prostředků pro léčení nebo.... |
| UA93004263A UA27780C2 (uk) | 1991-02-13 | 1992-02-08 | Діюча речовина лікарського засобу для лікування або профілактики артеріосклерозу та/або асоційованих з ним серцево-судинних захворювань, спосіб лікування або профілактики артеріосклерозу у ссавців та лікарський засіб, що в ньому використовується |
| SG1996007490A SG59972A1 (en) | 1991-02-13 | 1992-02-08 | Medicaments |
| CA002103805A CA2103805C (en) | 1991-02-13 | 1992-02-08 | Use of lacidipine for the treatment of arteriosclerosis |
| JP4503957A JP2996725B2 (ja) | 1991-02-13 | 1992-02-08 | 動脈硬化の治療のためのラシジピンの使用 |
| AU12231/92A AU646929B2 (en) | 1991-02-13 | 1992-02-08 | Use of lacidipine for the treatment of arteriosclerosis |
| AT92102146T ATE157004T1 (de) | 1991-02-13 | 1992-02-08 | Lacidipin zur behandlung der arteriosklerosis |
| IL10092892A IL100928A (en) | 1991-02-13 | 1992-02-12 | Use of lacidipine for the preparation of pharmaceutical compositions for the treatment and/or prevention of arteriosclerosis |
| IE045392A IE920453A1 (en) | 1991-02-13 | 1992-02-12 | Medicaments |
| PH43915A PH30130A (en) | 1991-02-13 | 1992-02-12 | Lacidipine for the treatment of arteriosclerosis |
| MX9200600A MX9200600A (es) | 1991-02-13 | 1992-02-12 | Medicamento que contiene lacidipina, para el tratamiento o prevencion de arteriosclerosis. |
| ZA921006A ZA921006B (en) | 1991-02-13 | 1992-02-12 | Medicaments |
| NO932874A NO303713B1 (no) | 1991-02-13 | 1993-08-12 | Anvendelse av lacidipin for behandling av arteriosklerose |
| KR1019930702402A KR100188171B1 (en) | 1991-02-13 | 1993-08-12 | Use of lacidipine for the treatment of arteriosclerosis |
| GR970402303T GR3024661T3 (en) | 1991-02-13 | 1997-09-09 | Lacidipine for the treatment of arteriosclerosis |
| HK98110314.1A HK1009585B (en) | 1991-02-13 | 1998-08-31 | Lacidipine for the treatment of arteriosclerosis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ITMI910359A IT1244728B (it) | 1991-02-13 | 1991-02-13 | Impiego medicamentoso di derivati diidropiridinici |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| ITMI910359A0 ITMI910359A0 (it) | 1991-02-13 |
| ITMI910359A1 ITMI910359A1 (it) | 1992-08-13 |
| IT1244728B true IT1244728B (it) | 1994-08-08 |
Family
ID=11358541
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ITMI910359A IT1244728B (it) | 1991-02-13 | 1991-02-13 | Impiego medicamentoso di derivati diidropiridinici |
Country Status (23)
| Country | Link |
|---|---|
| US (1) | US5455257A (it) |
| EP (2) | EP0499920B1 (it) |
| JP (1) | JP2996725B2 (it) |
| KR (1) | KR100188171B1 (it) |
| AT (1) | ATE157004T1 (it) |
| AU (1) | AU646929B2 (it) |
| CA (1) | CA2103805C (it) |
| CZ (1) | CZ281760B6 (it) |
| DE (1) | DE69221649T2 (it) |
| DK (1) | DK0499920T3 (it) |
| ES (1) | ES2106098T3 (it) |
| GR (1) | GR3024661T3 (it) |
| IE (1) | IE920453A1 (it) |
| IL (1) | IL100928A (it) |
| IT (1) | IT1244728B (it) |
| MX (1) | MX9200600A (it) |
| NO (1) | NO303713B1 (it) |
| PH (1) | PH30130A (it) |
| RU (1) | RU2136279C1 (it) |
| SG (1) | SG59972A1 (it) |
| UA (1) | UA27780C2 (it) |
| WO (1) | WO1992014460A1 (it) |
| ZA (1) | ZA921006B (it) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE69627137T2 (de) * | 1995-06-07 | 2003-12-04 | Ivax Research, Inc. | Verwendung von pentosan polysulfat zur behandlung von narben in chronischer fortschreitender gefässerkrankungen |
| RU2287327C2 (ru) * | 2003-10-16 | 2006-11-20 | Юрий Антонович Кошелев | Средство для лечения и профилактики атеросклероза |
| EP1868577A4 (en) * | 2005-04-15 | 2009-12-09 | Reddys Lab Inc Dr | Lacidipine PARTICLE |
| WO2007096694A1 (es) * | 2006-02-22 | 2007-08-30 | Ramiro Vergara | Asociacion de principios activos neuroactivadores |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS597163A (ja) * | 1982-07-02 | 1984-01-14 | Yamanouchi Pharmaceut Co Ltd | 抗動脈硬化剤 |
| NZ212895A (en) * | 1984-08-22 | 1988-07-28 | Glaxo Spa | 1,4-dihydropyridine derivatives and pharmaceutical compositions |
| GB8431119D0 (en) * | 1984-12-10 | 1985-01-16 | Fujisawa Pharmaceutical Co | Anti-arteriosclerotic composition |
-
1991
- 1991-02-13 IT ITMI910359A patent/IT1244728B/it active IP Right Grant
-
1992
- 1992-02-08 US US08/094,150 patent/US5455257A/en not_active Expired - Lifetime
- 1992-02-08 DE DE69221649T patent/DE69221649T2/de not_active Expired - Fee Related
- 1992-02-08 AU AU12231/92A patent/AU646929B2/en not_active Ceased
- 1992-02-08 UA UA93004263A patent/UA27780C2/uk unknown
- 1992-02-08 CA CA002103805A patent/CA2103805C/en not_active Expired - Fee Related
- 1992-02-08 RU RU93054780A patent/RU2136279C1/ru active
- 1992-02-08 DK DK92102146.5T patent/DK0499920T3/da active
- 1992-02-08 SG SG1996007490A patent/SG59972A1/en unknown
- 1992-02-08 AT AT92102146T patent/ATE157004T1/de not_active IP Right Cessation
- 1992-02-08 CZ CS931650A patent/CZ281760B6/cs not_active IP Right Cessation
- 1992-02-08 ES ES92102146T patent/ES2106098T3/es not_active Expired - Lifetime
- 1992-02-08 WO PCT/EP1992/000276 patent/WO1992014460A1/en not_active Ceased
- 1992-02-08 JP JP4503957A patent/JP2996725B2/ja not_active Expired - Fee Related
- 1992-02-08 EP EP92102146A patent/EP0499920B1/en not_active Expired - Lifetime
- 1992-02-08 EP EP92903946A patent/EP0576433A1/en not_active Withdrawn
- 1992-02-12 MX MX9200600A patent/MX9200600A/es unknown
- 1992-02-12 PH PH43915A patent/PH30130A/en unknown
- 1992-02-12 IE IE045392A patent/IE920453A1/en not_active IP Right Cessation
- 1992-02-12 IL IL10092892A patent/IL100928A/xx not_active IP Right Cessation
- 1992-02-12 ZA ZA921006A patent/ZA921006B/xx unknown
-
1993
- 1993-08-12 KR KR1019930702402A patent/KR100188171B1/ko not_active Expired - Fee Related
- 1993-08-12 NO NO932874A patent/NO303713B1/no not_active IP Right Cessation
-
1997
- 1997-09-09 GR GR970402303T patent/GR3024661T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| RU2136279C1 (ru) | 1999-09-10 |
| HK1009585A1 (en) | 1999-06-04 |
| CA2103805A1 (en) | 1992-08-14 |
| DK0499920T3 (da) | 1998-01-26 |
| UA27780C2 (uk) | 2000-10-16 |
| WO1992014460A1 (en) | 1992-09-03 |
| IL100928A (en) | 1997-02-18 |
| AU646929B2 (en) | 1994-03-10 |
| NO303713B1 (no) | 1998-08-24 |
| KR100188171B1 (en) | 1999-06-01 |
| CA2103805C (en) | 2002-09-17 |
| ZA921006B (en) | 1992-12-30 |
| DE69221649T2 (de) | 1997-12-11 |
| GR3024661T3 (en) | 1997-12-31 |
| CZ165093A3 (en) | 1994-03-16 |
| ATE157004T1 (de) | 1997-09-15 |
| DE69221649D1 (de) | 1997-09-25 |
| JPH06505002A (ja) | 1994-06-09 |
| NO932874D0 (no) | 1993-08-12 |
| CZ281760B6 (cs) | 1997-01-15 |
| EP0499920A1 (en) | 1992-08-26 |
| PH30130A (en) | 1997-01-21 |
| EP0499920B1 (en) | 1997-08-20 |
| US5455257A (en) | 1995-10-03 |
| ITMI910359A1 (it) | 1992-08-13 |
| EP0576433A1 (en) | 1994-01-05 |
| ES2106098T3 (es) | 1997-11-01 |
| AU1223192A (en) | 1992-09-15 |
| JP2996725B2 (ja) | 2000-01-11 |
| NO932874L (no) | 1993-08-12 |
| IE920453A1 (en) | 1992-08-12 |
| MX9200600A (es) | 1992-10-30 |
| SG59972A1 (en) | 1999-02-22 |
| ITMI910359A0 (it) | 1991-02-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 0001 | Granted | ||
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970227 |