CA2103805A1 - Use of lacidipine for the treatment of arteriosclerosis - Google Patents

Use of lacidipine for the treatment of arteriosclerosis

Info

Publication number
CA2103805A1
CA2103805A1 CA002103805A CA2103805A CA2103805A1 CA 2103805 A1 CA2103805 A1 CA 2103805A1 CA 002103805 A CA002103805 A CA 002103805A CA 2103805 A CA2103805 A CA 2103805A CA 2103805 A1 CA2103805 A1 CA 2103805A1
Authority
CA
Canada
Prior art keywords
lacidipine
arteriosclerosis
treatment
dimethylethoxy
propenyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CA002103805A
Other languages
French (fr)
Other versions
CA2103805C (en
Inventor
Giovanni Gaviraghi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
GlaxoSmithKline SpA
Original Assignee
Giovanni Gaviraghi
Glaxo S.P.A.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Giovanni Gaviraghi, Glaxo S.P.A. filed Critical Giovanni Gaviraghi
Publication of CA2103805A1 publication Critical patent/CA2103805A1/en
Application granted granted Critical
Publication of CA2103805C publication Critical patent/CA2103805C/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)

Abstract

The use of (E)-4-[2-[3-(1,1-dimethylethoxy)-3-oxo-1-propenyl]phenyl]-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid diethyl ester (lacidipine) for the treatment and/or prevention of arteriosclerosis.
CA002103805A 1991-02-13 1992-02-08 Use of lacidipine for the treatment of arteriosclerosis Expired - Fee Related CA2103805C (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI910359A IT1244728B (en) 1991-02-13 1991-02-13 MEDICAL USE OF DIHYDROPYRIDINE DERIVATIVES
ITMI91A000359 1991-02-13
PCT/EP1992/000276 WO1992014460A1 (en) 1991-02-13 1992-02-08 Use of lacidipine for the treatment of arteriosclerosis

Publications (2)

Publication Number Publication Date
CA2103805A1 true CA2103805A1 (en) 1992-08-14
CA2103805C CA2103805C (en) 2002-09-17

Family

ID=11358541

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002103805A Expired - Fee Related CA2103805C (en) 1991-02-13 1992-02-08 Use of lacidipine for the treatment of arteriosclerosis

Country Status (24)

Country Link
US (1) US5455257A (en)
EP (2) EP0576433A1 (en)
JP (1) JP2996725B2 (en)
KR (1) KR100188171B1 (en)
AT (1) ATE157004T1 (en)
AU (1) AU646929B2 (en)
CA (1) CA2103805C (en)
CZ (1) CZ281760B6 (en)
DE (1) DE69221649T2 (en)
DK (1) DK0499920T3 (en)
ES (1) ES2106098T3 (en)
GR (1) GR3024661T3 (en)
HK (1) HK1009585A1 (en)
IE (1) IE920453A1 (en)
IL (1) IL100928A (en)
IT (1) IT1244728B (en)
MX (1) MX9200600A (en)
NO (1) NO303713B1 (en)
PH (1) PH30130A (en)
RU (1) RU2136279C1 (en)
SG (1) SG59972A1 (en)
UA (1) UA27780C2 (en)
WO (1) WO1992014460A1 (en)
ZA (1) ZA921006B (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006113309A1 (en) * 2005-04-15 2006-10-26 Dr. Reddy's Laboratories Ltd. Lacidipine particles
WO2007096694A1 (en) * 2006-02-22 2007-08-30 Ramiro Vergara Combination of neuroactivating active principles

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597163A (en) * 1982-07-02 1984-01-14 Yamanouchi Pharmaceut Co Ltd Agent for lowering lipid level
NZ212895A (en) * 1984-08-22 1988-07-28 Glaxo Spa 1,4-dihydropyridine derivatives and pharmaceutical compositions
GB8431119D0 (en) * 1984-12-10 1985-01-16 Fujisawa Pharmaceutical Co Anti-arteriosclerotic composition

Also Published As

Publication number Publication date
ITMI910359A0 (en) 1991-02-13
DK0499920T3 (en) 1998-01-26
MX9200600A (en) 1992-10-30
NO303713B1 (en) 1998-08-24
IT1244728B (en) 1994-08-08
ES2106098T3 (en) 1997-11-01
KR100188171B1 (en) 1999-06-01
EP0576433A1 (en) 1994-01-05
DE69221649T2 (en) 1997-12-11
SG59972A1 (en) 1999-02-22
WO1992014460A1 (en) 1992-09-03
EP0499920A1 (en) 1992-08-26
RU2136279C1 (en) 1999-09-10
EP0499920B1 (en) 1997-08-20
AU646929B2 (en) 1994-03-10
NO932874L (en) 1993-08-12
IL100928A (en) 1997-02-18
HK1009585A1 (en) 1999-06-04
AU1223192A (en) 1992-09-15
CZ165093A3 (en) 1994-03-16
JPH06505002A (en) 1994-06-09
DE69221649D1 (en) 1997-09-25
IE920453A1 (en) 1992-08-12
ATE157004T1 (en) 1997-09-15
ITMI910359A1 (en) 1992-08-13
US5455257A (en) 1995-10-03
NO932874D0 (en) 1993-08-12
CA2103805C (en) 2002-09-17
ZA921006B (en) 1992-12-30
JP2996725B2 (en) 2000-01-11
UA27780C2 (en) 2000-10-16
PH30130A (en) 1997-01-21
GR3024661T3 (en) 1997-12-31
CZ281760B6 (en) 1997-01-15

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Legal Events

Date Code Title Description
EEER Examination request
MKLA Lapsed