IT1235153B - Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento - Google Patents

Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento

Info

Publication number
IT1235153B
IT1235153B IT8848558A IT4855888A IT1235153B IT 1235153 B IT1235153 B IT 1235153B IT 8848558 A IT8848558 A IT 8848558A IT 4855888 A IT4855888 A IT 4855888A IT 1235153 B IT1235153 B IT 1235153B
Authority
IT
Italy
Prior art keywords
treatment
carnitine
acetyl
cataract
pharmaceutical compositions
Prior art date
Application number
IT8848558A
Other languages
English (en)
Other versions
IT8848558A0 (it
Inventor
Claudio Cavazza
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Priority to IT8848558A priority Critical patent/IT1235153B/it
Publication of IT8848558A0 publication Critical patent/IT8848558A0/it
Priority to AT89830491T priority patent/ATE99172T1/de
Priority to ES89830491T priority patent/ES2062100T3/es
Priority to DE89830491T priority patent/DE68911891T2/de
Priority to EP89830491A priority patent/EP0375628B1/en
Priority to ZA898667A priority patent/ZA898667B/xx
Priority to US07/436,203 priority patent/US5037851A/en
Priority to JP1298729A priority patent/JPH02180820A/ja
Application granted granted Critical
Publication of IT1235153B publication Critical patent/IT1235153B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/12—Ophthalmic agents for cataracts

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Emergency Medicine (AREA)
  • Organic Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IT8848558A 1988-11-15 1988-11-15 Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento IT1235153B (it)

Priority Applications (8)

Application Number Priority Date Filing Date Title
IT8848558A IT1235153B (it) 1988-11-15 1988-11-15 Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento
AT89830491T ATE99172T1 (de) 1988-11-15 1989-11-13 Verwendung von acetyl-l-carnitin zur behandlung von katarakt, sowie pharmazeutische zusammensetzungen fuer eine derartige behandlung.
ES89830491T ES2062100T3 (es) 1988-11-15 1989-11-13 Empleo de acetil l-carnitina en el tratamiento terapeutico de cataratas y composiciones farmaceuticas utiles en este tratamiento.
DE89830491T DE68911891T2 (de) 1988-11-15 1989-11-13 Verwendung von Acetyl-L-carnitin zur Behandlung von Katarakt, sowie pharmazeutische Zusammensetzungen für eine derartige Behandlung.
EP89830491A EP0375628B1 (en) 1988-11-15 1989-11-13 Use of acetyl L-carnitine in the therapeutic treatment of cataract, and pharmaceutical compositions useful in such treatment
ZA898667A ZA898667B (en) 1988-11-15 1989-11-14 Use of acetyl l-carnitine in the therapeutic treatment of cataract and pharmaceutical compositions useful in such treatment
US07/436,203 US5037851A (en) 1988-11-15 1989-11-14 Use of acetyl l-carnitine in the therapeutic treatment of cataract, and pharmaceutical compositions useful in such treatment
JP1298729A JPH02180820A (ja) 1988-11-15 1989-11-15 アセチル―ｌ―カルニチン白内障処置剤

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT8848558A IT1235153B (it) 1988-11-15 1988-11-15 Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento

Publications (2)

Publication Number Publication Date
IT8848558A0 IT8848558A0 (it) 1988-11-15
IT1235153B true IT1235153B (it) 1992-06-22

Family

ID=11267312

Family Applications (1)

Application Number Title Priority Date Filing Date
IT8848558A IT1235153B (it) 1988-11-15 1988-11-15 Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento

Country Status (8)

Country Link
US (1) US5037851A (it)
EP (1) EP0375628B1 (it)
JP (1) JPH02180820A (it)
AT (1) ATE99172T1 (it)
DE (1) DE68911891T2 (it)
ES (1) ES2062100T3 (it)
IT (1) IT1235153B (it)
ZA (1) ZA898667B (it)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5668117A (en) * 1991-02-22 1997-09-16 Shapiro; Howard K. Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments
IT1254314B (it) * 1992-03-27 1995-09-14 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari.
IT1263004B (it) * 1992-10-08 1996-07-23 Sigma Tau Ind Farmaceuti Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti.
IT1276225B1 (it) * 1995-10-17 1997-10-27 Sigma Tau Ind Farmaceuti Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per
IT1276253B1 (it) 1995-12-15 1997-10-27 Sigma Tau Ind Farmaceuti Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi
IT1291113B1 (it) * 1997-03-20 1998-12-29 Sigma Tau Ind Farmaceuti Composizione nutritiva terapeutica per soggetti affetti da diabete mellito
US6090848A (en) * 1997-12-01 2000-07-18 Sigma-Tau Healthscience S.P.A. Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans
US5863940A (en) 1997-12-01 1999-01-26 Sigma-Tau Healthscience S.P.A. Medicament and therapeutical method for treating idiopathic asthenozoospermia
ES2210705T5 (es) 1998-03-19 2011-02-15 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Composición combinada que comprende una l-carnitina o una alcanoil-l-carnitina, un glucosaminoglucano y/o un constituyente del mismo.
ES2235499T3 (es) * 1998-07-30 2005-07-01 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Uso de derivados de propionil l-carnitina y de acetil l-carnitina en la preparacion de medicamentos con actividad anticancerigena.
ATE339445T1 (de) * 2000-12-15 2006-10-15 Sigma Tau Ind Farmaceuti Verwendung von l-carnitin als stabilitsator für proteine
US8569367B2 (en) 2004-11-16 2013-10-29 Allergan, Inc. Ophthalmic compositions and methods for treating eyes
EP1906949B1 (en) * 2005-07-01 2015-02-11 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Use of l-carnitine or of alkanoyl l-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops
JP5112308B2 (ja) 2005-07-08 2013-01-09 シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ 角膜疾患の治療のための食餌サプリメントまたは医薬の調製のためのｌ−カルニチンまたはアルカノイルｌ−カルニチン、脂溶性ベンゾキノンおよびオメガ−３−多価不飽和脂肪酸を含む組合せの使用
US20110015154A1 (en) * 2009-07-20 2011-01-20 Kellermann Gottfried H Supporting acetylcholine function
US20110098265A1 (en) * 2009-10-28 2011-04-28 Neuroscience, Inc. Methods for reducing cravings and impulses associated with addictive and compulsive behaviors
EP2363126A1 (en) 2010-03-04 2011-09-07 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Composition comprising as active ingredient L-carnitine in combination with hydroxykynurenine-O-beta-DL-glucoside, for the prevention and/or treatment of pathologies of the eye due to ultraviolet radiation
EP2642991A1 (en) 2010-11-22 2013-10-02 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Therapeutical method for the treatment of the leber optic
US9907826B2 (en) 2011-12-07 2018-03-06 Allergan, Inc. Efficient lipid delivery to human tear film using a salt-sensitive emulsion system
EP2783695A1 (en) 2013-03-28 2014-10-01 SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. Physiological supplement or medicament for ophthalmic use containing L-carnitine or alkanoyl L-carnitines in combination with eledoisin

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1184655B (it) * 1985-10-14 1987-10-28 Sigma Tau Ind Farmaceuti Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock

Also Published As

Publication number Publication date
US5037851A (en) 1991-08-06
EP0375628A3 (en) 1991-08-14
DE68911891D1 (de) 1994-02-10
JPH02180820A (ja) 1990-07-13
IT8848558A0 (it) 1988-11-15
ATE99172T1 (de) 1994-01-15
EP0375628A2 (en) 1990-06-27
ES2062100T3 (es) 1994-12-16
ZA898667B (en) 1990-10-31
DE68911891T2 (de) 1994-04-21
EP0375628B1 (en) 1993-12-29

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19931014