ATE99172T1 - Verwendung von acetyl-l-carnitin zur behandlung von katarakt, sowie pharmazeutische zusammensetzungen fuer eine derartige behandlung. - Google Patents
Verwendung von acetyl-l-carnitin zur behandlung von katarakt, sowie pharmazeutische zusammensetzungen fuer eine derartige behandlung.Info
- Publication number
- ATE99172T1 ATE99172T1 AT89830491T AT89830491T ATE99172T1 AT E99172 T1 ATE99172 T1 AT E99172T1 AT 89830491 T AT89830491 T AT 89830491T AT 89830491 T AT89830491 T AT 89830491T AT E99172 T1 ATE99172 T1 AT E99172T1
- Authority
- AT
- Austria
- Prior art keywords
- treatment
- carnitine
- acetyl
- cataract
- pharmaceutical compositions
- Prior art date
Links
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 title abstract 3
- 208000002177 Cataract Diseases 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8848558A IT1235153B (it) | 1988-11-15 | 1988-11-15 | Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento |
| EP89830491A EP0375628B1 (de) | 1988-11-15 | 1989-11-13 | Verwendung von Acetyl-L-carnitin zur Behandlung von Katarakt, sowie pharmazeutische Zusammensetzungen für eine derartige Behandlung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE99172T1 true ATE99172T1 (de) | 1994-01-15 |
Family
ID=11267312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT89830491T ATE99172T1 (de) | 1988-11-15 | 1989-11-13 | Verwendung von acetyl-l-carnitin zur behandlung von katarakt, sowie pharmazeutische zusammensetzungen fuer eine derartige behandlung. |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5037851A (de) |
| EP (1) | EP0375628B1 (de) |
| JP (1) | JPH02180820A (de) |
| AT (1) | ATE99172T1 (de) |
| DE (1) | DE68911891T2 (de) |
| ES (1) | ES2062100T3 (de) |
| IT (1) | IT1235153B (de) |
| ZA (1) | ZA898667B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| IT1254314B (it) * | 1992-03-27 | 1995-09-14 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari. |
| IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
| IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
| US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
| US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
| SI0951909T2 (sl) | 1998-03-19 | 2010-11-30 | Sigma Tau Ind Farmaceuti | Kombinirana zmes ki vsebuje L karnitin ali alkanoil L karnitin glikozaminoglikan in ali njegov sestavni del |
| DE69923322T2 (de) * | 1998-07-30 | 2005-12-22 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Verwendung von propionyl-l-carnitin und acetyl-l-carnitin zur herstellung von arzneimittel mit antikrebs wirkung |
| SK287787B6 (sk) * | 2000-12-15 | 2011-09-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Použitie L-karnitínu ako stabilizačného činidla proteínov |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| JP5117384B2 (ja) * | 2005-07-01 | 2013-01-16 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | 点眼剤の形態における眼用生理学的サプリメントまたは医薬の調製のためのl−カルニチンまたはアルカノイルl−カルニチンの使用 |
| AU2006268787B2 (en) | 2005-07-08 | 2012-02-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of a combination comprising L-carnitine or alkanoyl L-carnitine, lipid solubl benzoquinone and omega-3-polyunsaturated fatty acid for the preparation of a dietary supplement or medicament for the treatment of corneal diseases |
| US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
| US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
| EP2363126A1 (de) | 2010-03-04 | 2011-09-07 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Zusammensetzung mit L-Carnitin als aktivem Bestandteil in Kombination mit hydroxykynurenine-O-beta-DL-glucoside,zur Verhinderung und/oder Behandlung von Augenkrankheiten, die aufgrund der ultravioletten Strahlung entstanden sind |
| US9114120B2 (en) | 2010-11-22 | 2015-08-25 | Sigma-Tau Industrie Farmaceutiche Riunite, S.P.A. | Therapeutical method for the treatment of the Leber optic neuropathy |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| EP2783695A1 (de) | 2013-03-28 | 2014-10-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Physiologische Ergänzung oder Medikament zur ophthalmischen Verwendung mit L-Carnitin oder Alkanoyl-L-Carnitinen in Kombination mit Eledoisin |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1184655B (it) * | 1985-10-14 | 1987-10-28 | Sigma Tau Ind Farmaceuti | Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock |
-
1988
- 1988-11-15 IT IT8848558A patent/IT1235153B/it active
-
1989
- 1989-11-13 DE DE89830491T patent/DE68911891T2/de not_active Expired - Fee Related
- 1989-11-13 AT AT89830491T patent/ATE99172T1/de not_active IP Right Cessation
- 1989-11-13 EP EP89830491A patent/EP0375628B1/de not_active Expired - Lifetime
- 1989-11-13 ES ES89830491T patent/ES2062100T3/es not_active Expired - Lifetime
- 1989-11-14 ZA ZA898667A patent/ZA898667B/xx unknown
- 1989-11-14 US US07/436,203 patent/US5037851A/en not_active Expired - Lifetime
- 1989-11-15 JP JP1298729A patent/JPH02180820A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ZA898667B (en) | 1990-10-31 |
| DE68911891D1 (de) | 1994-02-10 |
| DE68911891T2 (de) | 1994-04-21 |
| IT1235153B (it) | 1992-06-22 |
| EP0375628A2 (de) | 1990-06-27 |
| IT8848558A0 (it) | 1988-11-15 |
| JPH02180820A (ja) | 1990-07-13 |
| US5037851A (en) | 1991-08-06 |
| ES2062100T3 (es) | 1994-12-16 |
| EP0375628A3 (de) | 1991-08-14 |
| EP0375628B1 (de) | 1993-12-29 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |