ZA898667B - Use of acetyl l-carnitine in the therapeutic treatment of cataract and pharmaceutical compositions useful in such treatment - Google Patents
Use of acetyl l-carnitine in the therapeutic treatment of cataract and pharmaceutical compositions useful in such treatmentInfo
- Publication number
- ZA898667B ZA898667B ZA898667A ZA898667A ZA898667B ZA 898667 B ZA898667 B ZA 898667B ZA 898667 A ZA898667 A ZA 898667A ZA 898667 A ZA898667 A ZA 898667A ZA 898667 B ZA898667 B ZA 898667B
- Authority
- ZA
- South Africa
- Prior art keywords
- treatment
- carnitine
- acetyl
- cataract
- pharmaceutical compositions
- Prior art date
Links
- RDHQFKQIGNGIED-MRVPVSSYSA-N O-acetyl-L-carnitine Chemical compound CC(=O)O[C@H](CC([O-])=O)C[N+](C)(C)C RDHQFKQIGNGIED-MRVPVSSYSA-N 0.000 title abstract 3
- 208000002177 Cataract Diseases 0.000 title abstract 2
- 230000001225 therapeutic effect Effects 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/205—Amine addition salts of organic acids; Inner quaternary ammonium salts, e.g. betaine, carnitine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
Landscapes
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Ophthalmology & Optometry (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT8848558A IT1235153B (it) | 1988-11-15 | 1988-11-15 | Uso dell'acetil l-carnitina nel trattamento terapeutico della cataratta e composizioni farmaceutiche utili in tale trattamento |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA898667B true ZA898667B (en) | 1990-10-31 |
Family
ID=11267312
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA898667A ZA898667B (en) | 1988-11-15 | 1989-11-14 | Use of acetyl l-carnitine in the therapeutic treatment of cataract and pharmaceutical compositions useful in such treatment |
Country Status (8)
| Country | Link |
|---|---|
| US (1) | US5037851A (de) |
| EP (1) | EP0375628B1 (de) |
| JP (1) | JPH02180820A (de) |
| AT (1) | ATE99172T1 (de) |
| DE (1) | DE68911891T2 (de) |
| ES (1) | ES2062100T3 (de) |
| IT (1) | IT1235153B (de) |
| ZA (1) | ZA898667B (de) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5668117A (en) * | 1991-02-22 | 1997-09-16 | Shapiro; Howard K. | Methods of treating neurological diseases and etiologically related symptomology using carbonyl trapping agents in combination with previously known medicaments |
| IT1254314B (it) * | 1992-03-27 | 1995-09-14 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche conyenenti l-carnitina e acil- carnitine inassociazione con ace-inibitori per il trattamento di patologie cardiovascolari. |
| IT1263004B (it) * | 1992-10-08 | 1996-07-23 | Sigma Tau Ind Farmaceuti | Impiego della l-carnitina e acil l-carnitine nel trattamento a lungo termine di pazienti diabetici non insulino-dipendenti. |
| IT1276225B1 (it) * | 1995-10-17 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizioni farmaceutiche contenenti l-carnitina e alcanoil l- carnitine in associazione con resveratrolo o suoi derivati utili per |
| IT1276253B1 (it) | 1995-12-15 | 1997-10-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica contenente l-carnitina o alcanoil l-carnitine per la prevenzione ed il trattamento di stati morbosi |
| IT1291113B1 (it) * | 1997-03-20 | 1998-12-29 | Sigma Tau Ind Farmaceuti | Composizione nutritiva terapeutica per soggetti affetti da diabete mellito |
| US5863940A (en) | 1997-12-01 | 1999-01-26 | Sigma-Tau Healthscience S.P.A. | Medicament and therapeutical method for treating idiopathic asthenozoospermia |
| US6090848A (en) * | 1997-12-01 | 2000-07-18 | Sigma-Tau Healthscience S.P.A. | Compositions and methods for increasing the concentration and/or motility of spermatozoa in humans |
| ATE254923T1 (de) | 1998-03-19 | 2003-12-15 | Sigma Tau Ind Farmaceuti | Kombinierte zusammensetzung bestehend aus l- karnitin oder l-alkanoylkarnitin, einem glycosaminoglycan und/oder einem seiner bestandteile |
| JP4703851B2 (ja) * | 1998-07-30 | 2011-06-15 | シグマ−タウ・インドゥストリエ・ファルマチェウチケ・リウニテ・ソシエタ・ペル・アチオニ | L−カルニチンおよびそのアルカノイル誘導体の、抗癌作用を有する医薬品の製造のための使用 |
| SK287787B6 (sk) * | 2000-12-15 | 2011-09-05 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Použitie L-karnitínu ako stabilizačného činidla proteínov |
| US8569367B2 (en) | 2004-11-16 | 2013-10-29 | Allergan, Inc. | Ophthalmic compositions and methods for treating eyes |
| AU2006265248B2 (en) * | 2005-07-01 | 2011-12-15 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Use of L-carnitine or of alkanoyl L-carnitines for the preparation of a physiological supplement or medicament for ophthalmic use in the form of eye-drops |
| CN101242818B (zh) | 2005-07-08 | 2011-09-21 | 希格马托制药工业公司 | 包含L-肉碱或烷酰基L-肉碱、脂溶性苯醌和ω-3-多不饱和脂肪酸的组合用于制备治疗角膜疾病的膳食补充剂或药物的用途 |
| US20110015154A1 (en) * | 2009-07-20 | 2011-01-20 | Kellermann Gottfried H | Supporting acetylcholine function |
| US20110098265A1 (en) * | 2009-10-28 | 2011-04-28 | Neuroscience, Inc. | Methods for reducing cravings and impulses associated with addictive and compulsive behaviors |
| EP2363126A1 (de) | 2010-03-04 | 2011-09-07 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Zusammensetzung mit L-Carnitin als aktivem Bestandteil in Kombination mit hydroxykynurenine-O-beta-DL-glucoside,zur Verhinderung und/oder Behandlung von Augenkrankheiten, die aufgrund der ultravioletten Strahlung entstanden sind |
| EP2642991A1 (de) | 2010-11-22 | 2013-10-02 | Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. | Therapeutisches verfahren zur behandlung der leberschen optikusatrophie |
| US9907826B2 (en) | 2011-12-07 | 2018-03-06 | Allergan, Inc. | Efficient lipid delivery to human tear film using a salt-sensitive emulsion system |
| EP2783695A1 (de) | 2013-03-28 | 2014-10-01 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Physiologische Ergänzung oder Medikament zur ophthalmischen Verwendung mit L-Carnitin oder Alkanoyl-L-Carnitinen in Kombination mit Eledoisin |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1184655B (it) * | 1985-10-14 | 1987-10-28 | Sigma Tau Ind Farmaceuti | Imiego di acetil l-carnitina nel trattamento terapeutico degli stati di shock |
-
1988
- 1988-11-15 IT IT8848558A patent/IT1235153B/it active
-
1989
- 1989-11-13 DE DE89830491T patent/DE68911891T2/de not_active Expired - Fee Related
- 1989-11-13 AT AT89830491T patent/ATE99172T1/de not_active IP Right Cessation
- 1989-11-13 EP EP89830491A patent/EP0375628B1/de not_active Expired - Lifetime
- 1989-11-13 ES ES89830491T patent/ES2062100T3/es not_active Expired - Lifetime
- 1989-11-14 US US07/436,203 patent/US5037851A/en not_active Expired - Lifetime
- 1989-11-14 ZA ZA898667A patent/ZA898667B/xx unknown
- 1989-11-15 JP JP1298729A patent/JPH02180820A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| JPH02180820A (ja) | 1990-07-13 |
| EP0375628A2 (de) | 1990-06-27 |
| ES2062100T3 (es) | 1994-12-16 |
| ATE99172T1 (de) | 1994-01-15 |
| EP0375628A3 (de) | 1991-08-14 |
| EP0375628B1 (de) | 1993-12-29 |
| US5037851A (en) | 1991-08-06 |
| DE68911891D1 (de) | 1994-02-10 |
| DE68911891T2 (de) | 1994-04-21 |
| IT8848558A0 (it) | 1988-11-15 |
| IT1235153B (it) | 1992-06-22 |
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