ATE206914T1 - Verwendung von ursolsäure zur herstellung eines arzneimittels zur unterdrückung von metastasen - Google Patents
Verwendung von ursolsäure zur herstellung eines arzneimittels zur unterdrückung von metastasenInfo
- Publication number
- ATE206914T1 ATE206914T1 AT96308340T AT96308340T ATE206914T1 AT E206914 T1 ATE206914 T1 AT E206914T1 AT 96308340 T AT96308340 T AT 96308340T AT 96308340 T AT96308340 T AT 96308340T AT E206914 T1 ATE206914 T1 AT E206914T1
- Authority
- AT
- Austria
- Prior art keywords
- ursolic acid
- produce
- medicinal product
- suppressing metastasis
- metastasis
- Prior art date
Links
- WCGUUGGRBIKTOS-GPOJBZKASA-N (3beta)-3-hydroxyurs-12-en-28-oic acid Chemical compound C1C[C@H](O)C(C)(C)[C@@H]2CC[C@@]3(C)[C@]4(C)CC[C@@]5(C(O)=O)CC[C@@H](C)[C@H](C)[C@H]5C4=CC[C@@H]3[C@]21C WCGUUGGRBIKTOS-GPOJBZKASA-N 0.000 title abstract 2
- 206010027476 Metastases Diseases 0.000 title abstract 2
- 230000009401 metastasis Effects 0.000 title abstract 2
- 229940096998 ursolic acid Drugs 0.000 title abstract 2
- PLSAJKYPRJGMHO-UHFFFAOYSA-N ursolic acid Natural products CC1CCC2(CCC3(C)C(C=CC4C5(C)CCC(O)C(C)(C)C5CCC34C)C2C1C)C(=O)O PLSAJKYPRJGMHO-UHFFFAOYSA-N 0.000 title abstract 2
- 229940126601 medicinal product Drugs 0.000 title 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 238000002347 injection Methods 0.000 abstract 1
- 239000007924 injection Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
Landscapes
- Health & Medical Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7323710A JP3041232B2 (ja) | 1995-11-16 | 1995-11-16 | 癌転移抑制剤 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE206914T1 true ATE206914T1 (de) | 2001-11-15 |
Family
ID=18157744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96308340T ATE206914T1 (de) | 1995-11-16 | 1996-11-15 | Verwendung von ursolsäure zur herstellung eines arzneimittels zur unterdrückung von metastasen |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US5985924A (de) |
| EP (1) | EP0774255B1 (de) |
| JP (1) | JP3041232B2 (de) |
| KR (1) | KR100424503B1 (de) |
| CN (1) | CN1073843C (de) |
| AT (1) | ATE206914T1 (de) |
| DE (1) | DE69615984T2 (de) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2775686B1 (fr) * | 1998-03-09 | 2006-07-28 | Pascal Commenil | Exploitation industrielle et commerciale des lipides cuticulaires de la baie de raisin en pharmacologie et cosmetologie |
| ATE262283T1 (de) * | 2000-02-10 | 2004-04-15 | Loders Croklaan Bv | Fettmischungen mit kristallmodifikatoren |
| EP1321145A4 (de) * | 2000-07-31 | 2006-03-22 | Nisshin Oillio Ltd | Antitumorwirkstoffe |
| AU2001283038A1 (en) * | 2000-07-31 | 2002-02-13 | University Of Virginia Patent Foundation | Inhibitors of dna polymerase sigma |
| JP2004518647A (ja) * | 2000-12-15 | 2004-06-24 | ナチュラルエンド テック カンパニー リミテッド | インシュリン様成長因子−1の分泌誘導用薬剤学的組成物および食品組成物 |
| US6979470B2 (en) * | 2001-07-17 | 2005-12-27 | Metaproteomics, Llc | Curcuminoid compositions exhibiting synergistic inhibition of the expression and/or activity of cyclooxygenase-2 |
| US20040029906A1 (en) * | 2001-07-31 | 2004-02-12 | Michael Christman | Inhibitors of dna polymerase sigma |
| EP1507542A4 (de) * | 2002-05-24 | 2008-01-23 | Greystone Medical Group Inc | Anti-krebs-formulierung |
| CN1243538C (zh) * | 2002-11-21 | 2006-03-01 | 武汉利元亨药物技术有限公司 | 熊果酸豆磷脂纳米粒冻干粉针及制备方法 |
| WO2005034958A1 (en) | 2003-10-10 | 2005-04-21 | Sk Chemicals, Co., Ltd. | Triterpene compounds which are effective on improvement of brain function |
| JP4810642B2 (ja) * | 2004-11-30 | 2011-11-09 | 秋田県 | 癌転移抑制用トリテルペン誘導体及び該トリテルペン誘導体を用いた癌転移抑制用組成物 |
| WO2014022772A1 (en) | 2012-08-03 | 2014-02-06 | University Of Iowa Research Foundation | Tomatidine, analogs thereof, compositions comprising same, and uses for same |
| US11090313B2 (en) | 2010-05-20 | 2021-08-17 | University Of Iowa Research Foundation | Methods for inhibiting muscle atrophy |
| CN103037692B (zh) | 2010-05-20 | 2015-02-25 | 爱荷华大学研究基金会 | 用于抑制肌萎缩的方法 |
| US9295664B2 (en) | 2011-06-06 | 2016-03-29 | University Of Iowa Research Foundation | Methods for lowering blood glucose |
| JP6548573B2 (ja) | 2012-07-05 | 2019-07-24 | ニュートラマックス ラボラトリーズ,インコーポレイテッド | スルホラファンまたはスルホラファン前駆体およびキノコ抽出物または粉末を含む組成物 |
| JP6211380B2 (ja) * | 2012-10-17 | 2017-10-11 | 丸善製薬株式会社 | Tie2活性化剤、血管新生抑制剤、血管の成熟化剤、血管の正常化剤、及び血管の安定化剤 |
| KR102155125B1 (ko) * | 2015-07-17 | 2020-09-11 | 경희대학교 산학협력단 | 악성 중피종 예방 또는 치료용 조성물 |
| CN105534991A (zh) * | 2015-12-24 | 2016-05-04 | 上海交通大学医学院 | 五环三萜类化合物在制备usp7抑制剂中的应用 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE707409A (de) * | 1967-12-01 | 1968-04-16 | ||
| JPS6439973A (en) * | 1987-08-06 | 1989-02-10 | Taiyo Kagaku Kk | Drink composition |
| JPH03287530A (ja) * | 1990-03-31 | 1991-12-18 | Snow Brand Milk Prod Co Ltd | 免疫抑制剤 |
| US5519008A (en) * | 1992-09-10 | 1996-05-21 | Glycomed Incorporated | Derivatives of triterpenoid acids as inhibitors of cell-adhesion molecules ELAM-1 (E-selectin) and LECAM-1 (L-selectin) |
| JPH0748250A (ja) * | 1993-06-04 | 1995-02-21 | Sekisui Chem Co Ltd | 眠気防止用テープ |
| US5643884A (en) * | 1993-08-09 | 1997-07-01 | Glycomed Incorporated | Lupane triterpenoid derivatives |
-
1995
- 1995-11-16 JP JP7323710A patent/JP3041232B2/ja not_active Expired - Fee Related
-
1996
- 1996-11-15 DE DE69615984T patent/DE69615984T2/de not_active Expired - Lifetime
- 1996-11-15 KR KR1019960054598A patent/KR100424503B1/ko not_active Expired - Fee Related
- 1996-11-15 AT AT96308340T patent/ATE206914T1/de not_active IP Right Cessation
- 1996-11-15 EP EP96308340A patent/EP0774255B1/de not_active Expired - Lifetime
- 1996-11-15 US US08/749,403 patent/US5985924A/en not_active Expired - Fee Related
- 1996-11-15 CN CN96114489A patent/CN1073843C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US5985924A (en) | 1999-11-16 |
| CN1073843C (zh) | 2001-10-31 |
| DE69615984T2 (de) | 2002-07-04 |
| EP0774255A1 (de) | 1997-05-21 |
| DE69615984D1 (de) | 2001-11-22 |
| KR100424503B1 (ko) | 2004-06-04 |
| JP3041232B2 (ja) | 2000-05-15 |
| CN1157716A (zh) | 1997-08-27 |
| EP0774255B1 (de) | 2001-10-17 |
| JPH09143076A (ja) | 1997-06-03 |
| KR970025615A (ko) | 1997-06-24 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |