DE1118326T1 - Reduzierung von durch Liposomen induzierten physiologischen Gegenreaktionen - Google Patents
Reduzierung von durch Liposomen induzierten physiologischen GegenreaktionenInfo
- Publication number
- DE1118326T1 DE1118326T1 DE1118326T DE01100692T DE1118326T1 DE 1118326 T1 DE1118326 T1 DE 1118326T1 DE 1118326 T DE1118326 T DE 1118326T DE 01100692 T DE01100692 T DE 01100692T DE 1118326 T1 DE1118326 T1 DE 1118326T1
- Authority
- DE
- Germany
- Prior art keywords
- liposome
- liposomes
- reduction
- animal
- reactions induced
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002502 liposome Substances 0.000 title claims abstract 8
- 238000006243 chemical reaction Methods 0.000 title 1
- 239000002260 anti-inflammatory agent Substances 0.000 claims 1
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 1
- 230000036772 blood pressure Effects 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000000825 pharmaceutical preparation Substances 0.000 claims 1
- 239000000232 Lipid Bilayer Substances 0.000 abstract 2
- 230000002411 adverse Effects 0.000 abstract 2
- 239000012867 bioactive agent Substances 0.000 abstract 1
- 150000002632 lipids Chemical class 0.000 abstract 1
- 230000011514 reflex Effects 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/127—Liposomes
- A61K9/1271—Non-conventional liposomes, e.g. PEGylated liposomes, liposomes coated with polymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T428/00—Stock material or miscellaneous articles
- Y10T428/29—Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
- Y10T428/2982—Particulate matter [e.g., sphere, flake, etc.]
- Y10T428/2984—Microcapsule with fluid core [includes liposome]
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Dispersion Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Cardiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Heart & Thoracic Surgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Claims (1)
1. Verwendung eines entzündungshemmenden Mittels zur Herstellung eines
Medikaments zur Begrenzung der Blutdruckabnahme, die durch ein pharmazeutisches Präparat, das ein Liposom umfasst, induziert wird.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US6592893A | 1993-05-21 | 1993-05-21 | |
US20765194A | 1994-03-07 | 1994-03-07 |
Publications (1)
Publication Number | Publication Date |
---|---|
DE1118326T1 true DE1118326T1 (de) | 2002-04-18 |
Family
ID=26746185
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69429511T Expired - Fee Related DE69429511T2 (de) | 1993-05-21 | 1994-05-20 | Reduzierung von durch liposome induzierte physiologischen gegenreaktionen |
DE1118326T Pending DE1118326T1 (de) | 1993-05-21 | 1994-05-20 | Reduzierung von durch Liposomen induzierten physiologischen Gegenreaktionen |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69429511T Expired - Fee Related DE69429511T2 (de) | 1993-05-21 | 1994-05-20 | Reduzierung von durch liposome induzierte physiologischen gegenreaktionen |
Country Status (15)
Country | Link |
---|---|
US (2) | US5614214A (de) |
EP (2) | EP1118326A3 (de) |
JP (1) | JPH08510748A (de) |
KR (1) | KR960702297A (de) |
AT (1) | ATE210966T1 (de) |
AU (1) | AU680513B2 (de) |
CA (1) | CA2160118A1 (de) |
DE (2) | DE69429511T2 (de) |
DK (1) | DK0699068T3 (de) |
ES (2) | ES2165875T3 (de) |
GR (1) | GR20010300075T1 (de) |
NO (1) | NO954691L (de) |
NZ (1) | NZ267310A (de) |
PT (1) | PT699068E (de) |
WO (1) | WO1994027580A1 (de) |
Families Citing this family (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL314132A1 (en) * | 1993-11-04 | 1996-08-19 | Schering Ag | Method of obtained electrically charged liposomes |
US5885613A (en) * | 1994-09-30 | 1999-03-23 | The University Of British Columbia | Bilayer stabilizing components and their use in forming programmable fusogenic liposomes |
US5820873A (en) * | 1994-09-30 | 1998-10-13 | The University Of British Columbia | Polyethylene glycol modified ceramide lipids and liposome uses thereof |
ATE198419T1 (de) * | 1994-10-14 | 2001-01-15 | Liposome Co Inc | Etherlipid-liposomen und deren therapeutische verwendung |
US6673364B1 (en) | 1995-06-07 | 2004-01-06 | The University Of British Columbia | Liposome having an exchangeable component |
US5942246A (en) * | 1996-02-16 | 1999-08-24 | The Liposome Company, Inc. | Etherlipid containing multiple lipid liposomes |
US6007839A (en) * | 1996-02-16 | 1999-12-28 | The Liposome Company, Inc. | Preparation of pharmaceutical compositions containing etherlipid-containing multiple lipid liposomes |
US5965159A (en) * | 1996-02-16 | 1999-10-12 | The Liposome Company, Inc. | Etherlipid-containing multiple lipid liposomes |
US6667053B1 (en) | 1996-02-16 | 2003-12-23 | Elan Pharmaceuticals, Inc. | D and L etherlipid stereoisomers and liposomes |
USRE39042E1 (en) * | 1996-02-16 | 2006-03-28 | The Liposome Company, Inc. | Etherlipid-containing multiple lipid liposomes |
US20030199425A1 (en) * | 1997-06-27 | 2003-10-23 | Desai Neil P. | Compositions and methods for treatment of hyperplasia |
US6734171B1 (en) | 1997-10-10 | 2004-05-11 | Inex Pharmaceuticals Corp. | Methods for encapsulating nucleic acids in lipid bilayers |
EP0976394A1 (de) * | 1998-07-30 | 2000-02-02 | Biosearch Italia S.p.A. | Neue injizierbare Formulierungen |
US6593308B2 (en) * | 1999-12-03 | 2003-07-15 | The Regents Of The University Of California | Targeted drug delivery with a hyaluronan ligand |
JP2004524368A (ja) * | 2001-03-27 | 2004-08-12 | フェアーズ ファーマシューティカル リサーチ エヌ.ヴェー. | 低い水溶性を有する生物学的に活性な化合物を可溶化するための方法および組成物 |
AU2002311616B2 (en) * | 2001-06-25 | 2007-11-22 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | A method for preparation of vesicles loaded with biological material and different uses thereof |
US20030180348A1 (en) * | 2002-03-22 | 2003-09-25 | Levinson R. Saul | Transcellular drug delivery system |
US6811777B2 (en) | 2002-04-13 | 2004-11-02 | Allan Mishra | Compositions and minimally invasive methods for treating incomplete connective tissue repair |
US7462703B2 (en) * | 2003-01-31 | 2008-12-09 | Max-Delbruck-Centrum Fur Molekulare Medizin | Agent for gene transfer |
CN1319520C (zh) * | 2005-02-03 | 2007-06-06 | 上海交通大学 | 核苷膦酸类化合物的脂质体和脂质复合物制剂 |
WO2008063808A2 (en) * | 2006-10-24 | 2008-05-29 | Northwestern University | Encapsulated peptide amphiphile nanostructures |
US20100112081A1 (en) | 2008-10-07 | 2010-05-06 | Bioparadox, Llc | Use of platelet rich plasma composition in the treatment of cardiac conduction abnormalities |
EP2486923B1 (de) * | 2011-02-11 | 2015-09-09 | Dr. Felix Jäger und Dr. Stefan Drinkuth Laborgemeinschaft OHG | Histon-Deacetylase (HDAC) hemmende Verbindungen und Verfahren zu deren Herstellung |
US20140356893A1 (en) | 2013-06-04 | 2014-12-04 | Allan Mishra | Compositions and methods for using platelet-rich plasma for drug discovery, cell nuclear reprogramming, proliferation or differentiation |
US20210154307A1 (en) * | 2019-11-07 | 2021-05-27 | Northeastern University | Cationic nanostructures for intra-cartilage delivery of therapeutics and contrast agents |
Family Cites Families (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3577446A (en) * | 1968-09-09 | 1971-05-04 | American Home Prod | Phosphatidylalkanolamine derivatives |
US3993754A (en) * | 1974-10-09 | 1976-11-23 | The United States Of America As Represented By The United States Energy Research And Development Administration | Liposome-encapsulated actinomycin for cancer chemotherapy |
US4086257A (en) * | 1976-10-12 | 1978-04-25 | Sears Barry D | Phosphatidyl quaternary ammonium compounds |
CH624011A5 (de) * | 1977-08-05 | 1981-07-15 | Battelle Memorial Institute | |
CH621479A5 (de) * | 1977-08-05 | 1981-02-13 | Battelle Memorial Institute | |
US4235871A (en) * | 1978-02-24 | 1980-11-25 | Papahadjopoulos Demetrios P | Method of encapsulating biologically active materials in lipid vesicles |
US4522803A (en) * | 1983-02-04 | 1985-06-11 | The Liposome Company, Inc. | Stable plurilamellar vesicles, their preparation and use |
US4588578A (en) * | 1983-08-08 | 1986-05-13 | The Liposome Company, Inc. | Lipid vesicles prepared in a monophase |
US5030453A (en) * | 1983-03-24 | 1991-07-09 | The Liposome Company, Inc. | Stable plurilamellar vesicles |
WO1985000968A1 (en) * | 1983-09-06 | 1985-03-14 | Health Research, Inc. | Liposome delivery method for decreasing the toxicity of an antitumor drug |
US4721612A (en) * | 1984-04-12 | 1988-01-26 | The Liposome Company, Inc. | Steroidal liposomes |
US5008050A (en) * | 1984-06-20 | 1991-04-16 | The Liposome Company, Inc. | Extrusion technique for producing unilamellar vesicles |
CA1264668C (en) * | 1984-06-20 | 1990-01-23 | EXTRUSION TECHNIQUES FOR THE PRODUCTION OF LIPOSOMES | |
CA1270198A (en) * | 1984-08-08 | 1990-06-12 | Marcel B. Bally | Encapsulation of antineoplastic agents in liposomes |
US4880635B1 (en) * | 1984-08-08 | 1996-07-02 | Liposome Company | Dehydrated liposomes |
US5077056A (en) * | 1984-08-08 | 1991-12-31 | The Liposome Company, Inc. | Encapsulation of antineoplastic agents in liposomes |
JPS6188887A (ja) * | 1984-10-08 | 1986-05-07 | Meito Sangyo Kk | 酵素法1−o−アルキル−2−アシルグリセロリン脂質誘導体の製法 |
US4975282A (en) * | 1985-06-26 | 1990-12-04 | The Liposome Company, Inc. | Multilamellar liposomes having improved trapping efficiencies |
JP2579625B2 (ja) * | 1985-07-05 | 1997-02-05 | ザ リポソ−ム カンパニ−,インコ−ポレイテツド | 改良された取り込み効率を有するマルチラメラリポソ−ム |
PH26160A (en) * | 1985-08-19 | 1992-03-18 | Univ Texas | Pharmaceutical compositions consisting of acylated phospholipids |
US5041278A (en) * | 1985-10-15 | 1991-08-20 | The Liposome Company, Inc. | Alpha tocopherol-based vesicles |
US4861580A (en) * | 1985-10-15 | 1989-08-29 | The Liposome Company, Inc. | Composition using salt form of organic acid derivative of alpha-tocopheral |
NZ223660A (en) * | 1987-03-05 | 1990-11-27 | Liposome Co Inc | Low toxicity drug-lipid complexes; methods of making them; and method of determining their toxicity |
CH672733A5 (de) * | 1987-05-22 | 1989-12-29 | Bracco Ind Chimica Spa | |
US5080833A (en) * | 1987-09-21 | 1992-01-14 | Kabushiki Kaisha Toshiba | Immobilization of bioactive substance on lipid composition containing modified lipid compound |
CA2056435A1 (en) * | 1989-05-15 | 1990-11-16 | Thomas D. Madden | Accumulation of drugs into liposomes by a proton gradient |
US5013556A (en) * | 1989-10-20 | 1991-05-07 | Liposome Technology, Inc. | Liposomes with enhanced circulation time |
DK0555317T3 (da) * | 1990-10-09 | 1995-08-07 | Nexstar Pharmaceuticals Inc | Phospholipid-analog-vesikel med en succinimidylsubstituent |
US5313804A (en) * | 1993-04-23 | 1994-05-24 | Maritime Geothermal Ltd. | Direct expansion geothermal heat pump |
-
1994
- 1994-05-20 JP JP7500895A patent/JPH08510748A/ja not_active Withdrawn
- 1994-05-20 AU AU69568/94A patent/AU680513B2/en not_active Ceased
- 1994-05-20 AT AT94918106T patent/ATE210966T1/de not_active IP Right Cessation
- 1994-05-20 US US08/247,053 patent/US5614214A/en not_active Expired - Lifetime
- 1994-05-20 DE DE69429511T patent/DE69429511T2/de not_active Expired - Fee Related
- 1994-05-20 ES ES94918106T patent/ES2165875T3/es not_active Expired - Lifetime
- 1994-05-20 KR KR1019950705072A patent/KR960702297A/ko not_active Application Discontinuation
- 1994-05-20 EP EP01100692A patent/EP1118326A3/de not_active Withdrawn
- 1994-05-20 ES ES01100692T patent/ES2193005T1/es active Pending
- 1994-05-20 WO PCT/US1994/005824 patent/WO1994027580A1/en active IP Right Grant
- 1994-05-20 CA CA002160118A patent/CA2160118A1/en not_active Abandoned
- 1994-05-20 DK DK94918106T patent/DK0699068T3/da active
- 1994-05-20 EP EP94918106A patent/EP0699068B1/de not_active Expired - Lifetime
- 1994-05-20 DE DE1118326T patent/DE1118326T1/de active Pending
- 1994-05-20 NZ NZ267310A patent/NZ267310A/en unknown
- 1994-05-20 PT PT94918106T patent/PT699068E/pt unknown
-
1995
- 1995-05-04 US US08/433,665 patent/US5662930A/en not_active Expired - Lifetime
- 1995-11-20 NO NO954691A patent/NO954691L/no not_active Application Discontinuation
-
2001
- 2001-12-31 GR GR20010300075T patent/GR20010300075T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
DK0699068T3 (da) | 2002-03-11 |
EP0699068A1 (de) | 1996-03-06 |
WO1994027580A1 (en) | 1994-12-08 |
EP1118326A2 (de) | 2001-07-25 |
EP0699068B1 (de) | 2001-12-19 |
US5614214A (en) | 1997-03-25 |
DE69429511T2 (de) | 2002-05-16 |
DE69429511D1 (de) | 2002-01-31 |
PT699068E (pt) | 2002-06-28 |
ATE210966T1 (de) | 2002-01-15 |
EP1118326A3 (de) | 2002-07-31 |
GR20010300075T1 (en) | 2001-12-31 |
ES2165875T3 (es) | 2002-04-01 |
NO954691D0 (no) | 1995-11-20 |
NO954691L (no) | 1995-11-20 |
AU6956894A (en) | 1994-12-20 |
US5662930A (en) | 1997-09-02 |
ES2193005T1 (es) | 2003-11-01 |
NZ267310A (en) | 1996-09-25 |
AU680513B2 (en) | 1997-07-31 |
JPH08510748A (ja) | 1996-11-12 |
KR960702297A (ko) | 1996-04-27 |
CA2160118A1 (en) | 1994-12-08 |
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