ES2052000T3 - Procedimiento para preparar composiciones farmaceuticas que contienen pentamidina. - Google Patents

Procedimiento para preparar composiciones farmaceuticas que contienen pentamidina.

Info

Publication number
ES2052000T3
ES2052000T3 ES89303639T ES89303639T ES2052000T3 ES 2052000 T3 ES2052000 T3 ES 2052000T3 ES 89303639 T ES89303639 T ES 89303639T ES 89303639 T ES89303639 T ES 89303639T ES 2052000 T3 ES2052000 T3 ES 2052000T3
Authority
ES
Spain
Prior art keywords
pentamidine
procedure
pharmaceutical compositions
compositions containing
less
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES89303639T
Other languages
English (en)
Inventor
Aloysius Anaebonam
Emmett Clemente
Theresa Devlin
Diane Rindgen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fisons Corp
Original Assignee
Fisons Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fisons Corp filed Critical Fisons Corp
Application granted granted Critical
Publication of ES2052000T3 publication Critical patent/ES2052000T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Saccharide Compounds (AREA)

Abstract

UNA SOLUCION ACUOSA QUE CONTIENE COMO INGREDIENTE PENTAMIDINA O UNA SAL DE ESTO FARMACEUTICAMENTE ACEPTABLE, Y CON UN PH DE MENOS DE 4.5 ES MAS ESTABLE QUE LAS SOLUCIONES CONVENCIONALES DE PENTAMIDINA. EL PH DE LA SOLUCION ES PREFERIBLEMENTE MENOR DE 4.0, MAS PREFERIBLEMENTE MENOR DE 3.5 Y ESPECIALMENTE MENOR DE 3.0. EL INGREDIENTE ACTIVO ES PREFERIBLEMENTE ISETIONATO DE PENTAMIDINA Y EL PH DE LA SOLUCION SE AJUSTA ESPECIALMENTE PREFERIBLEMENTE POR INCORPORACION DE ACIDO CLORHIDRICO. LAS SOLUCIONES PUEDEN SER ADMINISTRADAS DIRECTAMENTE AL PULMON POR NEBULIZACION Y SON UTILES EN EL TRATAMIENTO DE NEUMONIA NEUMO CISTICA CARIMII.
ES89303639T 1988-04-25 1989-04-12 Procedimiento para preparar composiciones farmaceuticas que contienen pentamidina. Expired - Lifetime ES2052000T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/185,463 US4853416A (en) 1988-04-25 1988-04-25 Solutions of pentamidine

Publications (1)

Publication Number Publication Date
ES2052000T3 true ES2052000T3 (es) 1994-07-01

Family

ID=22681079

Family Applications (1)

Application Number Title Priority Date Filing Date
ES89303639T Expired - Lifetime ES2052000T3 (es) 1988-04-25 1989-04-12 Procedimiento para preparar composiciones farmaceuticas que contienen pentamidina.

Country Status (11)

Country Link
US (1) US4853416A (es)
EP (1) EP0345926B1 (es)
JP (1) JP2729079B2 (es)
AT (1) ATE65914T1 (es)
CA (1) CA1326453C (es)
DE (1) DE68900187D1 (es)
DK (1) DK175485B1 (es)
ES (1) ES2052000T3 (es)
GR (1) GR3002835T3 (es)
IE (1) IE61150B1 (es)
PT (1) PT90356B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5364615A (en) * 1987-12-23 1994-11-15 Regents Of The University Of California Prophylaxis of pneumocystis carinii with aerosilized pentamidine
US5366726A (en) * 1987-12-23 1994-11-22 The Regents Of The University Of California Suppression of Pneumocystis carinii using aerosolized pentamidine treatment
GB8903438D0 (en) * 1989-02-15 1989-04-05 May & Baker Ltd New compositions of matter
US5162361A (en) * 1990-04-10 1992-11-10 The United States Of America As Represented By The Secretary, Department Of Health And Human Services Method of treating diseases associated with elevated levels of interleukin 1
US5230897A (en) * 1991-10-31 1993-07-27 G. D. Searle & Co. Transdermal pentamidine
EP1504755A1 (en) * 2002-05-13 2005-02-09 Daiichi Pharmaceutical Co., Ltd. Lyophilization product
US7947741B2 (en) * 2004-03-17 2011-05-24 Mpex Pharmaceuticals, Inc. Use and administration of bacterial efflux pump inhibitors
US7994225B2 (en) * 2004-03-17 2011-08-09 Rempex Pharmaceuticals, Inc. Bacterial efflux pump inhibitors for the treatment of ophthalmic and otic infections
JP6370801B2 (ja) 2012-12-21 2018-08-08 ベルリクス・ファーマ・インコーポレイテッド 肝疾患または肝障害の治療のための使用および方法
US11642372B2 (en) * 2020-05-01 2023-05-09 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses
US11826382B2 (en) 2020-05-01 2023-11-28 Tygrus, LLC Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3533494A1 (de) * 1985-09-17 1987-03-19 Meyer Glauner Wilhelm Dr Aerosol-anwendung von pentamidin (p,p'-(pentamethylen-dioxy)-dibenzamidin-bis(ss-hydroxyethansulfonat) zur behandlung der durch pneumocystis carinii bedingten lungenentzuendung
AU620025B2 (en) * 1987-03-26 1992-02-13 Sloan-Kettering Institute For Cancer Research Method of preventing pneumocystis carinii pneumonia using pentamidine in an aerosol form

Also Published As

Publication number Publication date
US4853416A (en) 1989-08-01
DK175485B1 (da) 2004-11-08
DK197089A (da) 1989-10-26
DE68900187D1 (de) 1991-09-12
EP0345926A1 (en) 1989-12-13
IE891314L (en) 1989-10-25
GR3002835T3 (en) 1993-01-25
DK197089D0 (da) 1989-04-24
PT90356B (pt) 1994-07-29
IE61150B1 (en) 1994-10-05
JPH0222223A (ja) 1990-01-25
CA1326453C (en) 1994-01-25
ATE65914T1 (de) 1991-08-15
PT90356A (pt) 1989-11-10
EP0345926B1 (en) 1991-08-07
JP2729079B2 (ja) 1998-03-18

Similar Documents

Publication Publication Date Title
ATE73331T1 (de) Verwendung von tetrahydrobiopterinen zur herstellung eines medikaments zur behandlung von kinderautismus.
HUT47217A (en) Process for producing pharmaceutical compositions containing indol derivatives as active components
ES2052000T3 (es) Procedimiento para preparar composiciones farmaceuticas que contienen pentamidina.
ATE206914T1 (de) Verwendung von ursolsäure zur herstellung eines arzneimittels zur unterdrückung von metastasen
BR9401199A (pt) Preparados de medicamentos, processo para a preparação de um preparado de medicamento, processo para a preparação de uma formulação de medicamento.
ATE135909T1 (de) Verfahren zur behandlung von akne
HUT57204A (en) Process for producing 4-fluoro-2-///4-methoxy-2-pyridinyl/-methyl/-sulfinyl/-1h-benzimidazol with gastric acid secration-diminishing activity and pharmaceutical compositions containing them
BE1002239A5 (fr) Solution pharmaceutique.
FR2712809B1 (fr) Nouvelle composition pharmaceutique destinée à la préparation d'une poudre stable contenant, à titre d'ingrédient actif, une association d'acide acétylsalicylique et de métoclopramide.
ATE117313T1 (de) Stabile lösungen von rebeccamycinderivaten sowie deren herstellung.
ATE204474T1 (de) Amethocain enthaltende arzneimittel
DE3688787D1 (de) Herstellung eines arzneimittels gegen arthritis und rheumatismus.
MY101266A (en) Pharmaceutical formulations
IT1184287B (it) Composizione per la preparazione di un medicamento da usare per la cura della piorrea alveolare
KR870700024A (ko) 약, 비타민 또는 왁진의 근육내 주사용 제제
ATE203903T1 (de) Delta-aminolävulinsäure enthaltendes arzneimittel
DE68901852T2 (de) Primycin-loesungen.
JPS643123A (en) Remedy for skin inflammation
JPS6442434A (en) Gepilone for alleviating fright trouble
DE3786168D1 (de) Verwendung von para-aminobenzoesaeure zur herstellung eines arzneimittels zur bekaempfung von photoallergien.
BE904737A (fr) Derives de l'acide octenoique.

Legal Events

Date Code Title Description
FG2A Definitive protection

Ref document number: 345926

Country of ref document: ES