FI896014A0 - Heterocykliska derivat. - Google Patents
Heterocykliska derivat.Info
- Publication number
- FI896014A0 FI896014A0 FI896014A FI896014A FI896014A0 FI 896014 A0 FI896014 A0 FI 896014A0 FI 896014 A FI896014 A FI 896014A FI 896014 A FI896014 A FI 896014A FI 896014 A0 FI896014 A0 FI 896014A0
- Authority
- FI
- Finland
- Prior art keywords
- heterocyclis
- derivatives
- heterocyclis derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/04—Seven-membered rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88403313 | 1988-12-23 | ||
EP89401491 | 1989-05-31 |
Publications (1)
Publication Number | Publication Date |
---|---|
FI896014A0 true FI896014A0 (fi) | 1989-12-15 |
Family
ID=26118235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI896014A FI896014A0 (fi) | 1988-12-23 | 1989-12-15 | Heterocykliska derivat. |
Country Status (16)
Country | Link |
---|---|
US (1) | US5098930A (fi) |
EP (1) | EP0375404B1 (fi) |
JP (1) | JPH03135975A (fi) |
AU (1) | AU624663B2 (fi) |
CA (1) | CA2006377A1 (fi) |
DE (1) | DE68913022T2 (fi) |
DK (1) | DK654589A (fi) |
ES (1) | ES2062051T3 (fi) |
FI (1) | FI896014A0 (fi) |
GB (1) | GB8926981D0 (fi) |
HU (1) | HUT52767A (fi) |
IE (1) | IE63047B1 (fi) |
IL (1) | IL92556A (fi) |
NO (1) | NO895086L (fi) |
NZ (1) | NZ231665A (fi) |
PT (1) | PT92699B (fi) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
IE911919A1 (en) * | 1990-06-21 | 1992-01-01 | Zeneca Ltd | Bicyclic heterocyclic compounds |
US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
EP0462830B1 (en) * | 1990-06-21 | 1995-10-18 | Zeneca Limited | Cyclic ether derivatives |
IE911853A1 (en) * | 1990-06-21 | 1992-01-01 | Ici Plc | Heterocyclene derivatives |
GB9113137D0 (en) * | 1990-07-13 | 1991-08-07 | Ici Plc | Thioxo heterocycles |
IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
US5272173A (en) * | 1990-11-28 | 1993-12-21 | Imperial Chemical Industries Plc | 5-lipoxygenase inhibitors |
IE914005A1 (en) * | 1990-12-14 | 1992-06-17 | Zeneca Ltd | Novel intermediates |
CA2058254A1 (en) * | 1991-01-15 | 1992-07-16 | John Francis Kingston | Benzodioxole derivatives |
US5258399A (en) * | 1991-01-17 | 1993-11-02 | Imperial Chemical Industries Plc | Sulphonamide derivatives |
IL100483A0 (en) * | 1991-01-17 | 1992-09-06 | Ici Plc | Sulphonamide derivatives |
EP0501579A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Naphthalene lactones as inhibitors of leukotriene biosynthesis |
US5227399A (en) * | 1991-02-28 | 1993-07-13 | Merck Frosst Canada, Inc. | Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0501578A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
EP0505122A1 (en) * | 1991-03-21 | 1992-09-23 | Zeneca Limited | Alpha, alpha-dialkylbenzyl derivatives |
DE69206725T2 (de) * | 1991-09-10 | 1996-05-02 | Zeneca Ltd | Benzolsulfonamidderivate als 5-Lipoxygenasehemmer |
EP0540165A1 (en) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkanoic acid derivatives |
GB9300894D0 (en) * | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
EP0555067A1 (en) * | 1992-02-07 | 1993-08-11 | Zeneca Limited | Hydroxylamine derivatives as 5-lipoxygenase inhibitors |
CA2094465A1 (en) * | 1992-04-23 | 1993-10-24 | Pierre Andre Raymond Bruneau | Cycloalkane derivatives |
EP0570196B1 (en) * | 1992-05-12 | 1996-03-06 | Zeneca Limited | Oxime derivatives |
CA2095006A1 (en) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Oxime derivatives |
CA2095005A1 (en) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Hydroxylamine derivatives |
EP0570197B1 (en) * | 1992-05-12 | 1995-12-13 | Zeneca Limited | Hydroxylamine derivatives |
US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
EP0586229A1 (en) * | 1992-09-01 | 1994-03-09 | Zeneca Limited | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors |
AU4444393A (en) * | 1992-09-01 | 1994-03-10 | Zeneca Limited | Pyrrolidine derivatives |
US5354865A (en) * | 1992-09-10 | 1994-10-11 | Abbott Laboratories | Phenylmethyl derivatives having lipoxygenase inhibitory activity |
GR920100426A (el) * | 1992-10-08 | 1994-06-30 | Ici Pharma | Παράγωγα βενζολοσουλφοναμιδίου. |
IL109254A (en) * | 1993-04-29 | 1999-03-12 | Zeneca Ltd | History of the tetrahydropyran and tetrahydropuran site preparation and pharmaceutical preparations containing them |
DE69403795T2 (de) * | 1993-06-14 | 1997-09-18 | Pfizer | Imidazole als lipoxygenase inhibitoren |
IL110280A0 (en) * | 1993-07-27 | 1994-10-21 | Zeneca Ltd | Thiazole derivatives |
EP0636624A1 (en) * | 1993-07-27 | 1995-02-01 | Zeneca Limited | Thiazole derivatives as lipoxygenase inhibitors |
ZA945250B (en) * | 1993-07-27 | 1995-01-27 | Zeneca Ltd | Thiazole derivatives |
US5446062A (en) * | 1993-11-12 | 1995-08-29 | Abbott Laboratories | ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase |
US5407959A (en) * | 1993-11-12 | 1995-04-18 | Abbott Laboratories | (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase |
WO1995026346A1 (en) * | 1994-03-28 | 1995-10-05 | Pfizer Inc. | Benzisothiazoles derivatives as inhibitors of 5-lipoxygenase biosynthesis |
WO1995030669A1 (en) * | 1994-05-06 | 1995-11-16 | Zeneca Limited | Ether derivatives and pharmaceutical compositions containing them |
DE59813344D1 (de) | 1997-11-03 | 2006-04-06 | Aventis Res & Tech Gmbh & Co | Fluorierte naphthalin-derivate und ihre verwendung in flüssigkristallinen mischungen |
CA2269561C (en) | 1998-04-22 | 2007-06-05 | Dainippon Ink And Chemicals, Inc. | Naphthalene derivative and liquid crystal composition comprising the same |
CN1468055A (zh) * | 2000-10-03 | 2004-01-14 | �����ɷ� | 苯基丙炔基羟吡啶除草剂 |
US6825221B2 (en) | 2001-10-18 | 2004-11-30 | Allergan, Inc. | Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain |
US7846915B2 (en) | 2004-10-20 | 2010-12-07 | Resverlogix Corporation | Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases |
JP5368792B2 (ja) | 2005-07-29 | 2013-12-18 | レスバーロジックス コーポレイション | 複合疾患の予防および処置のための薬学的組成物および挿入可能な医療用デバイスによるその送達 |
DK2118074T3 (en) | 2007-02-01 | 2014-03-10 | Resverlogix Corp | Compounds for the prevention and treatment of cardiovascular diseases |
US8114995B2 (en) | 2008-06-26 | 2012-02-14 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
ES2463097T3 (es) | 2009-01-08 | 2014-05-27 | Resverlogix Corp. | Compuestos para la prevención y el tratamiento de enfermedades cardiovasculares |
CA3146333A1 (en) | 2009-03-18 | 2010-09-23 | Resverlogix Corp. | Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents |
SI2421533T1 (sl) | 2009-04-22 | 2019-01-31 | Resverlogix Corp. | Nova protivnetna sredstva |
CN103945848B (zh) | 2011-11-01 | 2016-09-07 | 雷斯韦洛吉克斯公司 | 被取代的喹唑啉酮的口服即释制剂 |
WO2014080290A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
CN105073744B (zh) | 2012-12-21 | 2019-11-08 | 齐尼思表观遗传学有限公司 | 作为溴结构域抑制剂的新型杂环化合物 |
JP6903585B2 (ja) | 2015-03-13 | 2021-07-14 | レスバーロジックス コーポレイション | 補体関連疾患の治療のための組成物および治療方法 |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3661917A (en) * | 1970-05-21 | 1972-05-09 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols |
CA960676A (en) * | 1970-05-21 | 1975-01-07 | Smith Kline And French Canada Ltd. | 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols |
US3743737A (en) * | 1970-05-21 | 1973-07-03 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions |
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
GB8306512D0 (en) * | 1983-03-09 | 1983-04-13 | Ici Plc | Heterocyclic compounds |
NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
US4625034A (en) * | 1985-02-04 | 1986-11-25 | Usv Pharmaceutical Corp. | 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
FR2611714A2 (fr) * | 1986-04-23 | 1988-09-09 | Rhone Poulenc Agrochimie | Composes a groupements triazole ou imidazole et tetrahydrofuran, utilisation de ceux-ci a titre de fongicides et procedes de preparation |
EP0271287A3 (en) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Quinoline dioic acids and amides |
US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920130A (en) * | 1987-11-02 | 1990-04-24 | Rorer Pharamceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920133A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920131A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4918081A (en) * | 1988-06-20 | 1990-04-17 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene d4 |
EP0349062A1 (en) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Quinoline ether alkanoic acid |
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
-
1989
- 1989-11-29 GB GB898926981A patent/GB8926981D0/en active Pending
- 1989-12-05 IL IL9255689A patent/IL92556A/xx not_active IP Right Cessation
- 1989-12-05 IE IE388089A patent/IE63047B1/en not_active IP Right Cessation
- 1989-12-07 NZ NZ231665A patent/NZ231665A/en unknown
- 1989-12-12 AU AU46198/89A patent/AU624663B2/en not_active Ceased
- 1989-12-15 HU HU896626A patent/HUT52767A/hu unknown
- 1989-12-15 FI FI896014A patent/FI896014A0/fi not_active Application Discontinuation
- 1989-12-18 NO NO89895086A patent/NO895086L/no unknown
- 1989-12-20 EP EP89313384A patent/EP0375404B1/en not_active Expired - Lifetime
- 1989-12-20 DE DE89313384T patent/DE68913022T2/de not_active Expired - Fee Related
- 1989-12-20 ES ES89313384T patent/ES2062051T3/es not_active Expired - Lifetime
- 1989-12-21 CA CA002006377A patent/CA2006377A1/en not_active Abandoned
- 1989-12-21 DK DK654589A patent/DK654589A/da not_active Application Discontinuation
- 1989-12-22 US US07/455,173 patent/US5098930A/en not_active Expired - Fee Related
- 1989-12-22 PT PT92699A patent/PT92699B/pt not_active IP Right Cessation
- 1989-12-25 JP JP1333012A patent/JPH03135975A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
HU896626D0 (en) | 1990-02-28 |
EP0375404B1 (en) | 1994-02-09 |
EP0375404A3 (en) | 1991-01-16 |
GB8926981D0 (en) | 1990-01-17 |
DE68913022D1 (de) | 1994-03-24 |
PT92699A (pt) | 1990-06-29 |
NZ231665A (en) | 1992-02-25 |
US5098930A (en) | 1992-03-24 |
IE893880L (en) | 1990-06-23 |
ES2062051T3 (es) | 1994-12-16 |
NO895086L (no) | 1990-06-25 |
IL92556A (en) | 1994-04-12 |
IE63047B1 (en) | 1995-03-22 |
AU4619889A (en) | 1990-06-28 |
DK654589A (da) | 1990-06-24 |
JPH03135975A (ja) | 1991-06-10 |
DK654589D0 (da) | 1989-12-21 |
HUT52767A (en) | 1990-08-28 |
DE68913022T2 (de) | 1994-05-11 |
EP0375404A2 (en) | 1990-06-27 |
NO895086D0 (no) | 1989-12-18 |
PT92699B (pt) | 1995-09-12 |
CA2006377A1 (en) | 1990-06-23 |
IL92556A0 (en) | 1990-08-31 |
AU624663B2 (en) | 1992-06-18 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI896014A0 (fi) | Heterocykliska derivat. | |
DE122004000043I1 (de) | Carbostryril-Derivate. | |
ATE74125T1 (de) | Didehydro-vitamin d3-derivate. | |
FI895049A0 (fi) | Derivat av loeslig t-4. | |
DE69008682D1 (de) | Guanidinobenzolderivate. | |
DE58901056D1 (de) | Dehydrocholecalciferolderivate. | |
FI891122A0 (fi) | N-cyklopropylaniliner och deras anvaendning i foerfarandet foer framstaellning av 1-cyklopropylkinolonkarboxylsyror och deras derivat. | |
ATE124407T1 (de) | Chromanderivate. | |
DE69022965T2 (de) | Aminopiperazinderivate. | |
ATE126800T1 (de) | Neplanocinderivate. | |
FI860622A (fi) | Heterocykliska derivat. | |
DE69017383D1 (de) | Substituierte bicycloheptadionderivate. | |
ATE116985T1 (de) | Chromanderivate. | |
DE68911192T2 (de) | Phosphonoalkylpurin-Derivate. | |
DE69017657D1 (de) | Pyridinderivate. | |
DE58903265D1 (de) | Fluorcyclopropyl-derivate. | |
DE69005904T2 (de) | Phenylpyrimidonderivate. | |
DE59000510D1 (de) | N-phenyltetrahydroindazolderivate. | |
DE68913856T2 (de) | Cycloalkylthiazol-Derivate. | |
DE59003499D1 (de) | 3-Cyano-4-phenyl-pyrrol-Derivate. | |
ATE109478T1 (de) | Pyridin-derivate. | |
NO892714L (no) | Substituerte azacykloheksylderivater. | |
DE69015726D1 (de) | Piperidylthiocarbapenem-Derivate. | |
DE58900371D1 (de) | 3-cyano-4-phenyl-pyrrol-derivate. | |
DE68906854T2 (de) | Dihydropyridinderivate. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |
Owner name: ICI PHARMA Owner name: IMPERIAL CHEMICAL INDUSTRIES PLC |