DK654589D0 - Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne - Google Patents
Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterneInfo
- Publication number
- DK654589D0 DK654589D0 DK654589A DK654589A DK654589D0 DK 654589 D0 DK654589 D0 DK 654589D0 DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A DK 654589 D0 DK654589 D0 DK 654589D0
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- procedures
- preparing
- pharmaceutical agents
- agents containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D309/10—Oxygen atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/04—Seven-membered rings not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pain & Pain Management (AREA)
- Immunology (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP88403313 | 1988-12-23 | ||
EP89401491 | 1989-05-31 |
Publications (2)
Publication Number | Publication Date |
---|---|
DK654589D0 true DK654589D0 (da) | 1989-12-21 |
DK654589A DK654589A (da) | 1990-06-24 |
Family
ID=26118235
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK654589A DK654589A (da) | 1988-12-23 | 1989-12-21 | Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne |
Country Status (16)
Country | Link |
---|---|
US (1) | US5098930A (da) |
EP (1) | EP0375404B1 (da) |
JP (1) | JPH03135975A (da) |
AU (1) | AU624663B2 (da) |
CA (1) | CA2006377A1 (da) |
DE (1) | DE68913022T2 (da) |
DK (1) | DK654589A (da) |
ES (1) | ES2062051T3 (da) |
FI (1) | FI896014A0 (da) |
GB (1) | GB8926981D0 (da) |
HU (1) | HUT52767A (da) |
IE (1) | IE63047B1 (da) |
IL (1) | IL92556A (da) |
NO (1) | NO895086L (da) |
NZ (1) | NZ231665A (da) |
PT (1) | PT92699B (da) |
Families Citing this family (60)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
US5254581A (en) * | 1990-06-21 | 1993-10-19 | Imperial Chemical Industries Plc | Pyran derivatives and their use as inhibitors of 5-lipoxygenase |
IE911853A1 (en) * | 1990-06-21 | 1992-01-01 | Ici Plc | Heterocyclene derivatives |
AU637500B2 (en) * | 1990-06-21 | 1993-05-27 | Zeneca Limited | Bicyclic heterocyclic compounds |
EP0462830B1 (en) * | 1990-06-21 | 1995-10-18 | Zeneca Limited | Cyclic ether derivatives |
GB9113137D0 (en) * | 1990-07-13 | 1991-08-07 | Ici Plc | Thioxo heterocycles |
US5272173A (en) * | 1990-11-28 | 1993-12-21 | Imperial Chemical Industries Plc | 5-lipoxygenase inhibitors |
IE913866A1 (en) * | 1990-11-28 | 1992-06-03 | Ici Plc | Aryl derivatives |
IE914005A1 (en) * | 1990-12-14 | 1992-06-17 | Zeneca Ltd | Novel intermediates |
CA2058254A1 (en) * | 1991-01-15 | 1992-07-16 | John Francis Kingston | Benzodioxole derivatives |
US5258399A (en) * | 1991-01-17 | 1993-11-02 | Imperial Chemical Industries Plc | Sulphonamide derivatives |
IL100483A0 (en) * | 1991-01-17 | 1992-09-06 | Ici Plc | Sulphonamide derivatives |
US5281720A (en) * | 1991-02-28 | 1994-01-25 | Merck Frosst Canada, Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
EP0501578A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis |
US5227399A (en) * | 1991-02-28 | 1993-07-13 | Merck Frosst Canada, Inc. | Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0501579A1 (en) * | 1991-02-28 | 1992-09-02 | Merck Frosst Canada Inc. | Naphthalene lactones as inhibitors of leukotriene biosynthesis |
EP0505122A1 (en) * | 1991-03-21 | 1992-09-23 | Zeneca Limited | Alpha, alpha-dialkylbenzyl derivatives |
EP0532239B1 (en) * | 1991-09-10 | 1995-12-13 | Zeneca Limited | Benzenesulphonamide derivatives as 5-lipoxygenase inhibitors |
EP0540165A1 (en) * | 1991-10-03 | 1993-05-05 | Zeneca Limited | Alkanoic acid derivatives |
GB9300894D0 (en) * | 1992-02-07 | 1993-03-10 | Zeneca Ltd | Oxime derivatives |
EP0555067A1 (en) * | 1992-02-07 | 1993-08-11 | Zeneca Limited | Hydroxylamine derivatives as 5-lipoxygenase inhibitors |
CA2094465A1 (en) * | 1992-04-23 | 1993-10-24 | Pierre Andre Raymond Bruneau | Cycloalkane derivatives |
CA2095005A1 (en) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Hydroxylamine derivatives |
EP0570197B1 (en) * | 1992-05-12 | 1995-12-13 | Zeneca Limited | Hydroxylamine derivatives |
CA2095006A1 (en) * | 1992-05-12 | 1993-11-13 | Philip Neil Edwards | Oxime derivatives |
EP0570196B1 (en) * | 1992-05-12 | 1996-03-06 | Zeneca Limited | Oxime derivatives |
US5308852A (en) * | 1992-06-29 | 1994-05-03 | Merck Frosst Canada, Inc. | Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis |
US5426109A (en) * | 1992-08-27 | 1995-06-20 | Merck Frosst Canada, Inc. | Phenylnaphthalene hydroxy acids |
US5350744A (en) * | 1992-08-27 | 1994-09-27 | Merck Frosst Canada, Inc. | Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5428060A (en) * | 1992-08-27 | 1995-06-27 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis |
US5252599A (en) * | 1992-08-27 | 1993-10-12 | Merck Frosst Canada, Inc. | Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis |
AU4444393A (en) * | 1992-09-01 | 1994-03-10 | Zeneca Limited | Pyrrolidine derivatives |
EP0586229A1 (en) * | 1992-09-01 | 1994-03-09 | Zeneca Limited | 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors |
US5354865A (en) * | 1992-09-10 | 1994-10-11 | Abbott Laboratories | Phenylmethyl derivatives having lipoxygenase inhibitory activity |
GR920100426A (el) * | 1992-10-08 | 1994-06-30 | Ici Pharma | Παράγωγα βενζολοσουλφοναμιδίου. |
IL109254A (en) * | 1993-04-29 | 1999-03-12 | Zeneca Ltd | History of the tetrahydropyran and tetrahydropuran site preparation and pharmaceutical preparations containing them |
BR9406822A (pt) * | 1993-06-14 | 1996-03-26 | Pfizer | Inibidores imidazol de lipoxigenase |
IL110280A0 (en) * | 1993-07-27 | 1994-10-21 | Zeneca Ltd | Thiazole derivatives |
ZA945250B (en) * | 1993-07-27 | 1995-01-27 | Zeneca Ltd | Thiazole derivatives |
EP0636624A1 (en) * | 1993-07-27 | 1995-02-01 | Zeneca Limited | Thiazole derivatives as lipoxygenase inhibitors |
US5446062A (en) * | 1993-11-12 | 1995-08-29 | Abbott Laboratories | ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase |
US5407959A (en) * | 1993-11-12 | 1995-04-18 | Abbott Laboratories | (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase |
ES2119377T3 (es) * | 1994-03-28 | 1998-10-01 | Pfizer | Derivados bencisotiazoles inhibidores de la biosintesis de la 5-lipoxigenasa. |
WO1995030669A1 (en) * | 1994-05-06 | 1995-11-16 | Zeneca Limited | Ether derivatives and pharmaceutical compositions containing them |
DE59813344D1 (de) | 1997-11-03 | 2006-04-06 | Aventis Res & Tech Gmbh & Co | Fluorierte naphthalin-derivate und ihre verwendung in flüssigkristallinen mischungen |
CA2269561C (en) * | 1998-04-22 | 2007-06-05 | Dainippon Ink And Chemicals, Inc. | Naphthalene derivative and liquid crystal composition comprising the same |
AU1820002A (en) * | 2000-10-03 | 2002-04-15 | Syngenta Participations Ag | Phenylpropynyloxypyridine herbicides |
US6825221B2 (en) | 2001-10-18 | 2004-11-30 | Allergan, Inc. | Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain |
EP2332527A3 (en) | 2004-10-20 | 2011-11-16 | Resverlogix Corp. | Flavanoids and Isoflavanoids for the prevention and treatment of cardiovascular diseases |
AU2006275514B2 (en) | 2005-07-29 | 2012-04-05 | Resverlogix Corp. | Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices |
PT2118074E (pt) | 2007-02-01 | 2014-03-20 | Resverlogix Corp | Compostos para a prevenção e tratamento de doenças cardiovasculares |
CA2711103C (en) | 2008-06-26 | 2016-08-09 | Resverlogix Corp. | Methods of preparing quinazolinone derivatives |
CA2747417C (en) | 2009-01-08 | 2017-01-03 | Resverlogix Corp. | Compounds for the prevention and treatment of cardiovascular disease |
CA3146333A1 (en) | 2009-03-18 | 2010-09-23 | Resverlogix Corp. | Phenyl-quinazolin-4(3h)-one and phenyl-pyrido[2,3-d]pyrimidin-4(3h)-one derivatives and compositions thereof useful as anti-inflammatory agents |
LT2421533T (lt) | 2009-04-22 | 2018-12-27 | Resverlogix Corp. | Nauji priešuždegiminiai agentai |
JP5992049B2 (ja) | 2011-11-01 | 2016-09-14 | レスバーロジックス コーポレイション | 置換されたキナゾリノンのための経口速放性製剤 |
US9073878B2 (en) | 2012-11-21 | 2015-07-07 | Zenith Epigenetics Corp. | Cyclic amines as bromodomain inhibitors |
WO2014080291A2 (en) | 2012-11-21 | 2014-05-30 | Rvx Therapeutics Inc. | Biaryl derivatives as bromodomain inhibitors |
AU2013365926B9 (en) | 2012-12-21 | 2019-01-17 | Zenith Epigenetics Ltd. | Novel heterocyclic compounds as bromodomain inhibitors |
WO2016147053A1 (en) | 2015-03-13 | 2016-09-22 | Resverlogix Corp. | Compositions and therapeutic methods for the treatment of complement-associated diseases |
Family Cites Families (17)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3743737A (en) * | 1970-05-21 | 1973-07-03 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions |
CA960676A (en) * | 1970-05-21 | 1975-01-07 | Smith Kline And French Canada Ltd. | 3-sulfonamido-4-hydroxyphenyl-2-piperidinylcarbinols |
US3661917A (en) * | 1970-05-21 | 1972-05-09 | Smith Kline French Lab | 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols |
IE56702B1 (en) * | 1982-12-01 | 1991-11-06 | Usv Pharma Corp | Antiinflammatory antiallergic compounds |
GB8306512D0 (en) * | 1983-03-09 | 1983-04-13 | Ici Plc | Heterocyclic compounds |
NZ213986A (en) * | 1984-10-30 | 1989-07-27 | Usv Pharma Corp | Heterocyclic or aromatic compounds, and pharmaceutical compositions containing such |
US4625034A (en) * | 1985-02-04 | 1986-11-25 | Usv Pharmaceutical Corp. | 1,2-Dihydro; 1,2,3,4-tetrahydro; 5,8 dihydro; and 5,6,7,8-tetrahydroquinoline derivatives |
US4839369A (en) * | 1985-04-16 | 1989-06-13 | Rorer Pharmaceutical Corporation | Aryl and heteroaryl ethers as agents for the treatment of hypersensitive ailments |
FR2611714A2 (fr) * | 1986-04-23 | 1988-09-09 | Rhone Poulenc Agrochimie | Composes a groupements triazole ou imidazole et tetrahydrofuran, utilisation de ceux-ci a titre de fongicides et procedes de preparation |
EP0271287A3 (en) * | 1986-12-11 | 1990-06-13 | Merck Frosst Canada Inc. | Quinoline dioic acids and amides |
US4920132A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920133A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920130A (en) * | 1987-11-02 | 1990-04-24 | Rorer Pharamceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4920131A (en) * | 1987-11-03 | 1990-04-24 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene D4 |
US4918081A (en) * | 1988-06-20 | 1990-04-17 | Rorer Pharmaceutical Corp. | Quinoline derivatives and use thereof as antagonists of leukotriene d4 |
EP0349062A1 (en) * | 1988-06-27 | 1990-01-03 | Merck Frosst Canada Inc. | Quinoline ether alkanoic acid |
IE64358B1 (en) * | 1989-07-18 | 1995-07-26 | Ici Plc | Diaryl ether heterocycles |
-
1989
- 1989-11-29 GB GB898926981A patent/GB8926981D0/en active Pending
- 1989-12-05 IE IE388089A patent/IE63047B1/en not_active IP Right Cessation
- 1989-12-05 IL IL9255689A patent/IL92556A/xx not_active IP Right Cessation
- 1989-12-07 NZ NZ231665A patent/NZ231665A/en unknown
- 1989-12-12 AU AU46198/89A patent/AU624663B2/en not_active Ceased
- 1989-12-15 HU HU896626A patent/HUT52767A/hu unknown
- 1989-12-15 FI FI896014A patent/FI896014A0/fi not_active Application Discontinuation
- 1989-12-18 NO NO89895086A patent/NO895086L/no unknown
- 1989-12-20 EP EP89313384A patent/EP0375404B1/en not_active Expired - Lifetime
- 1989-12-20 DE DE89313384T patent/DE68913022T2/de not_active Expired - Fee Related
- 1989-12-20 ES ES89313384T patent/ES2062051T3/es not_active Expired - Lifetime
- 1989-12-21 DK DK654589A patent/DK654589A/da not_active Application Discontinuation
- 1989-12-21 CA CA002006377A patent/CA2006377A1/en not_active Abandoned
- 1989-12-22 US US07/455,173 patent/US5098930A/en not_active Expired - Fee Related
- 1989-12-22 PT PT92699A patent/PT92699B/pt not_active IP Right Cessation
- 1989-12-25 JP JP1333012A patent/JPH03135975A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
IL92556A (en) | 1994-04-12 |
JPH03135975A (ja) | 1991-06-10 |
ES2062051T3 (es) | 1994-12-16 |
DE68913022D1 (de) | 1994-03-24 |
GB8926981D0 (en) | 1990-01-17 |
DK654589A (da) | 1990-06-24 |
IL92556A0 (en) | 1990-08-31 |
AU624663B2 (en) | 1992-06-18 |
IE893880L (en) | 1990-06-23 |
EP0375404A3 (en) | 1991-01-16 |
HUT52767A (en) | 1990-08-28 |
NZ231665A (en) | 1992-02-25 |
NO895086L (no) | 1990-06-25 |
CA2006377A1 (en) | 1990-06-23 |
DE68913022T2 (de) | 1994-05-11 |
FI896014A0 (fi) | 1989-12-15 |
PT92699B (pt) | 1995-09-12 |
IE63047B1 (en) | 1995-03-22 |
HU896626D0 (en) | 1990-02-28 |
NO895086D0 (no) | 1989-12-18 |
PT92699A (pt) | 1990-06-29 |
EP0375404A2 (en) | 1990-06-27 |
EP0375404B1 (en) | 1994-02-09 |
US5098930A (en) | 1992-03-24 |
AU4619889A (en) | 1990-06-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AHB | Application shelved due to non-payment |