DK654589A - Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne - Google Patents

Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne Download PDF

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Publication number
DK654589A
DK654589A DK654589A DK654589A DK654589A DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A DK 654589 A DK654589 A DK 654589A
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DK
Denmark
Prior art keywords
derivatives
procedures
preparing
pharmaceutical agents
agents containing
Prior art date
Application number
DK654589A
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English (en)
Other versions
DK654589D0 (da
Inventor
Philip Neil Edwards
Jean-Marc Marie Mauri Girodeau
Original Assignee
Ici Pharma
Ici Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ici Pharma, Ici Plc filed Critical Ici Pharma
Publication of DK654589D0 publication Critical patent/DK654589D0/da
Publication of DK654589A publication Critical patent/DK654589A/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D307/20—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
    • C07D313/02—Seven-membered rings
    • C07D313/04—Seven-membered rings not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pulmonology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Furan Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
DK654589A 1988-12-23 1989-12-21 Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne DK654589A (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88403313 1988-12-23
EP89401491 1989-05-31

Publications (2)

Publication Number Publication Date
DK654589D0 DK654589D0 (da) 1989-12-21
DK654589A true DK654589A (da) 1990-06-24

Family

ID=26118235

Family Applications (1)

Application Number Title Priority Date Filing Date
DK654589A DK654589A (da) 1988-12-23 1989-12-21 Heterocykliske derivater, fremgangsmaade til fremstilling deraf samt farmaceutiske midler indeholdende derivaterne

Country Status (16)

Country Link
US (1) US5098930A (da)
EP (1) EP0375404B1 (da)
JP (1) JPH03135975A (da)
AU (1) AU624663B2 (da)
CA (1) CA2006377A1 (da)
DE (1) DE68913022T2 (da)
DK (1) DK654589A (da)
ES (1) ES2062051T3 (da)
FI (1) FI896014A0 (da)
GB (1) GB8926981D0 (da)
HU (1) HUT52767A (da)
IE (1) IE63047B1 (da)
IL (1) IL92556A (da)
NO (1) NO895086L (da)
NZ (1) NZ231665A (da)
PT (1) PT92699B (da)

Families Citing this family (60)

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IE64358B1 (en) * 1989-07-18 1995-07-26 Ici Plc Diaryl ether heterocycles
AU637500B2 (en) * 1990-06-21 1993-05-27 Zeneca Limited Bicyclic heterocyclic compounds
EP0462830B1 (en) * 1990-06-21 1995-10-18 Zeneca Limited Cyclic ether derivatives
IE911853A1 (en) * 1990-06-21 1992-01-01 Ici Plc Heterocyclene derivatives
US5254581A (en) * 1990-06-21 1993-10-19 Imperial Chemical Industries Plc Pyran derivatives and their use as inhibitors of 5-lipoxygenase
GB9113137D0 (en) * 1990-07-13 1991-08-07 Ici Plc Thioxo heterocycles
IE913866A1 (en) * 1990-11-28 1992-06-03 Ici Plc Aryl derivatives
US5272173A (en) * 1990-11-28 1993-12-21 Imperial Chemical Industries Plc 5-lipoxygenase inhibitors
IE914005A1 (en) * 1990-12-14 1992-06-17 Zeneca Ltd Novel intermediates
CA2058254A1 (en) * 1991-01-15 1992-07-16 John Francis Kingston Benzodioxole derivatives
IL100483A0 (en) * 1991-01-17 1992-09-06 Ici Plc Sulphonamide derivatives
US5258399A (en) * 1991-01-17 1993-11-02 Imperial Chemical Industries Plc Sulphonamide derivatives
US5281720A (en) * 1991-02-28 1994-01-25 Merck Frosst Canada, Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
EP0501579A1 (en) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Naphthalene lactones as inhibitors of leukotriene biosynthesis
EP0501578A1 (en) * 1991-02-28 1992-09-02 Merck Frosst Canada Inc. Pyranylphenyl hydroxyalkylnaphthoic acids as inhibitors of leukotriene biosynthesis
US5227399A (en) * 1991-02-28 1993-07-13 Merck Frosst Canada, Inc. Pyranylphenyl naphthalene lactones as inhibitors of leukotriene biosynthesis
EP0505122A1 (en) * 1991-03-21 1992-09-23 Zeneca Limited Alpha, alpha-dialkylbenzyl derivatives
DE69206725T2 (de) * 1991-09-10 1996-05-02 Zeneca Ltd Benzolsulfonamidderivate als 5-Lipoxygenasehemmer
EP0540165A1 (en) * 1991-10-03 1993-05-05 Zeneca Limited Alkanoic acid derivatives
EP0555067A1 (en) * 1992-02-07 1993-08-11 Zeneca Limited Hydroxylamine derivatives as 5-lipoxygenase inhibitors
GB9300894D0 (en) * 1992-02-07 1993-03-10 Zeneca Ltd Oxime derivatives
CA2094465A1 (en) * 1992-04-23 1993-10-24 Pierre Andre Raymond Bruneau Cycloalkane derivatives
CA2095006A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Oxime derivatives
CA2095005A1 (en) * 1992-05-12 1993-11-13 Philip Neil Edwards Hydroxylamine derivatives
EP0570196B1 (en) * 1992-05-12 1996-03-06 Zeneca Limited Oxime derivatives
EP0570197B1 (en) * 1992-05-12 1995-12-13 Zeneca Limited Hydroxylamine derivatives
US5308852A (en) * 1992-06-29 1994-05-03 Merck Frosst Canada, Inc. Heteroarylnaphthalenes as inhibitors of leukotriene biosynthesis
US5426109A (en) * 1992-08-27 1995-06-20 Merck Frosst Canada, Inc. Phenylnaphthalene hydroxy acids
US5428060A (en) * 1992-08-27 1995-06-27 Merck Frosst Canada, Inc. Heteroarylnaphthalene lactones as inhibitors of leukotriene biosynthesis
US5252599A (en) * 1992-08-27 1993-10-12 Merck Frosst Canada, Inc. Heteroarylnaphthalene hydroxy acids as inhibitors of leukotriene biosynthesis
US5350744A (en) * 1992-08-27 1994-09-27 Merck Frosst Canada, Inc. Phenylnaphthalene lactones as inhibitors of leukotriene biosynthesis
EP0586229A1 (en) * 1992-09-01 1994-03-09 Zeneca Limited 3-Hydroxy-3-(subst-akyl)-pyrrolidines as 5-lipoxygenase inhibitors
AU4444393A (en) * 1992-09-01 1994-03-10 Zeneca Limited Pyrrolidine derivatives
US5354865A (en) * 1992-09-10 1994-10-11 Abbott Laboratories Phenylmethyl derivatives having lipoxygenase inhibitory activity
GR920100426A (el) * 1992-10-08 1994-06-30 Ici Pharma Παράγωγα βενζολοσουλφοναμιδίου.
IL109254A (en) * 1993-04-29 1999-03-12 Zeneca Ltd History of the tetrahydropyran and tetrahydropuran site preparation and pharmaceutical preparations containing them
DE69403795T2 (de) * 1993-06-14 1997-09-18 Pfizer Imidazole als lipoxygenase inhibitoren
EP0636624A1 (en) * 1993-07-27 1995-02-01 Zeneca Limited Thiazole derivatives as lipoxygenase inhibitors
ZA945250B (en) * 1993-07-27 1995-01-27 Zeneca Ltd Thiazole derivatives
IL110280A0 (en) * 1993-07-27 1994-10-21 Zeneca Ltd Thiazole derivatives
US5446062A (en) * 1993-11-12 1995-08-29 Abbott Laboratories ((4-alkoxypyran-4-yl) substituted) ether, arylalkyl-, arylalkenyl-, and arylalkynyl)urea inhibitors of 5-lipoxygenase
US5407959A (en) * 1993-11-12 1995-04-18 Abbott Laboratories (Trans-1,4-dialkoxycyclohexyl) substituted arylalkylaryl-arylalkenylaryl-, and arylalkynylarylurea inhibitors of 5-lipoxygenase
WO1995026346A1 (en) * 1994-03-28 1995-10-05 Pfizer Inc. Benzisothiazoles derivatives as inhibitors of 5-lipoxygenase biosynthesis
WO1995030669A1 (en) * 1994-05-06 1995-11-16 Zeneca Limited Ether derivatives and pharmaceutical compositions containing them
DE59813344D1 (de) * 1997-11-03 2006-04-06 Aventis Res & Tech Gmbh & Co Fluorierte naphthalin-derivate und ihre verwendung in flüssigkristallinen mischungen
CA2269561C (en) * 1998-04-22 2007-06-05 Dainippon Ink And Chemicals, Inc. Naphthalene derivative and liquid crystal composition comprising the same
US20040102325A1 (en) * 2000-10-03 2004-05-27 Schaetzer Juergen Phenylpropynyloxypyridine herbicides
US6825221B2 (en) 2001-10-18 2004-11-30 Allergan, Inc. Arylsulfanyl and heteroarylsulfanyl derivatives for treating pain
US7846915B2 (en) 2004-10-20 2010-12-07 Resverlogix Corporation Stilbenes and chalcones for the prevention and treatment of cardiovascular diseases
NZ566180A (en) 2005-07-29 2011-04-29 Resverlogix Corp Pharmaceutical compositions for the prevention and treatment of complex diseases and their delivery by insertable medical devices
US8053440B2 (en) 2007-02-01 2011-11-08 Resverlogix Corporation Compounds for the prevention and treatment of cardiovascular diseases
RU2520098C2 (ru) 2008-06-26 2014-06-20 Ресверлоджикс Корп. Способы получения производных хиназолинона
AU2010204106B2 (en) 2009-01-08 2014-05-08 Resverlogix Corp. Compounds for the prevention and treatment of cardiovascular disease
NZ617779A (en) 2009-03-18 2015-08-28 Resverlogix Corp Novel anti-inflammatory agents
KR20180096823A (ko) 2009-04-22 2018-08-29 리스버로직스 코퍼레이션 신규한 소염제
RS58911B1 (sr) 2011-11-01 2019-08-30 Resverlogix Corp Oralne formulacije sa trenutnim otpuštanjem za supstituisane hinazolinone
US9073878B2 (en) 2012-11-21 2015-07-07 Zenith Epigenetics Corp. Cyclic amines as bromodomain inhibitors
US9765039B2 (en) 2012-11-21 2017-09-19 Zenith Epigenetics Ltd. Biaryl derivatives as bromodomain inhibitors
JP2016507496A (ja) 2012-12-21 2016-03-10 ゼニス・エピジェネティクス・コーポレイションＺｅｎｉｔｈ Ｅｐｉｇｅｎｅｔｉｃｓ Ｃｏｒｐ． ブロモドメイン阻害剤としての新規複素環式化合物
US10111885B2 (en) 2015-03-13 2018-10-30 Resverlogix Corp. Compositions and therapeutic methods for the treatment of complement-associated diseases

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US3661917A (en) * 1970-05-21 1972-05-09 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperidylcarbinols
US3743737A (en) * 1970-05-21 1973-07-03 Smith Kline French Lab 3-sulfonamido-4-hydroxyphenyl-2-piperindinylcarbinol compositions
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Also Published As

Publication number Publication date
NZ231665A (en) 1992-02-25
DE68913022D1 (de) 1994-03-24
NO895086D0 (no) 1989-12-18
IL92556A0 (en) 1990-08-31
EP0375404A2 (en) 1990-06-27
AU624663B2 (en) 1992-06-18
DK654589D0 (da) 1989-12-21
IE893880L (en) 1990-06-23
IE63047B1 (en) 1995-03-22
EP0375404B1 (en) 1994-02-09
DE68913022T2 (de) 1994-05-11
CA2006377A1 (en) 1990-06-23
GB8926981D0 (en) 1990-01-17
NO895086L (no) 1990-06-25
HUT52767A (en) 1990-08-28
PT92699A (pt) 1990-06-29
IL92556A (en) 1994-04-12
US5098930A (en) 1992-03-24
ES2062051T3 (es) 1994-12-16
FI896014A0 (fi) 1989-12-15
AU4619889A (en) 1990-06-28
HU896626D0 (en) 1990-02-28
EP0375404A3 (en) 1991-01-16
PT92699B (pt) 1995-09-12
JPH03135975A (ja) 1991-06-10

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