SG11202100928QA - Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy - Google Patents

Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy

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Publication number
SG11202100928QA
SG11202100928QA SG11202100928QA SG11202100928QA SG11202100928QA SG 11202100928Q A SG11202100928Q A SG 11202100928QA SG 11202100928Q A SG11202100928Q A SG 11202100928QA SG 11202100928Q A SG11202100928Q A SG 11202100928QA SG 11202100928Q A SG11202100928Q A SG 11202100928QA
Authority
SG
Singapore
Prior art keywords
muscular dystrophy
facioscapulohumeral muscular
muscle targeting
targeting complexes
treating facioscapulohumeral
Prior art date
Application number
SG11202100928QA
Other languages
English (en)
Inventor
Romesh Subramanian
Mohammed Qatanani
Timothy Weeden
Original Assignee
Dyne Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dyne Therapeutics Inc filed Critical Dyne Therapeutics Inc
Publication of SG11202100928QA publication Critical patent/SG11202100928QA/en

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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/68—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an antibody, an immunoglobulin or a fragment thereof, e.g. an Fc-fragment
    • A61K47/6801—Drug-antibody or immunoglobulin conjugates defined by the pharmacologically or therapeutically active agent
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    • A61K47/6807—Drugs conjugated to an antibody or immunoglobulin, e.g. cisplatin-antibody conjugates the drug or compound being a sugar, nucleoside, nucleotide, nucleic acid, e.g. RNA antisense
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    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
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SG11202100928QA 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy SG11202100928QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201862713933P 2018-08-02 2018-08-02
PCT/US2019/044990 WO2020028864A1 (en) 2018-08-02 2019-08-02 Muscle targeting complexes and uses thereof for treating facioscapulohumeral muscular dystrophy

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SG11202100928QA true SG11202100928QA (en) 2021-02-25

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US (12) US20220193250A1 (https=)
EP (1) EP3830259A4 (https=)
JP (2) JP2021533200A (https=)
KR (1) KR20210081324A (https=)
CN (1) CN112912499A (https=)
AU (1) AU2019316103B2 (https=)
CA (1) CA3108289A1 (https=)
EA (1) EA202190416A1 (https=)
IL (1) IL280426A (https=)
MX (1) MX2021001284A (https=)
SG (1) SG11202100928QA (https=)
WO (1) WO2020028864A1 (https=)

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