SG11201607961QA - Quinoxaline derivatives useful as fgfr kinase modulators - Google Patents

Quinoxaline derivatives useful as fgfr kinase modulators

Info

Publication number
SG11201607961QA
SG11201607961QA SG11201607961QA SG11201607961QA SG11201607961QA SG 11201607961Q A SG11201607961Q A SG 11201607961QA SG 11201607961Q A SG11201607961Q A SG 11201607961QA SG 11201607961Q A SG11201607961Q A SG 11201607961QA SG 11201607961Q A SG11201607961Q A SG 11201607961QA
Authority
SG
Singapore
Prior art keywords
derivatives useful
quinoxaline derivatives
fgfr kinase
kinase modulators
modulators
Prior art date
Application number
SG11201607961QA
Other languages
English (en)
Inventor
Wim Vermeulen
Steven Anna Hostyn
Filip Albert Celine Cuyckens
Russell Mark Jones
Diego Fernando Domenico Broggini
Original Assignee
Astex Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50389854&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=SG11201607961Q(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Astex Therapeutics Ltd filed Critical Astex Therapeutics Ltd
Publication of SG11201607961QA publication Critical patent/SG11201607961QA/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/55—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole
    • A61K31/551—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having seven-membered rings, e.g. azelastine, pentylenetetrazole having two nitrogen atoms, e.g. dilazep
    • A61K31/5513—1,4-Benzodiazepines, e.g. diazepam or clozapine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SG11201607961QA 2014-03-26 2015-03-26 Quinoxaline derivatives useful as fgfr kinase modulators SG11201607961QA (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP14161820 2014-03-26
PCT/EP2015/056507 WO2015144803A1 (en) 2014-03-26 2015-03-26 Quinoxaline derivatives useful as fgfr kinase modulators

Publications (1)

Publication Number Publication Date
SG11201607961QA true SG11201607961QA (en) 2016-10-28

Family

ID=50389854

Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201607961QA SG11201607961QA (en) 2014-03-26 2015-03-26 Quinoxaline derivatives useful as fgfr kinase modulators

Country Status (38)

Country Link
US (2) US9902714B2 (https=)
EP (1) EP3122742B1 (https=)
JP (1) JP6625551B2 (https=)
KR (1) KR102469506B1 (https=)
CN (1) CN106459010B (https=)
AP (1) AP2016009536A0 (https=)
AR (1) AR099854A1 (https=)
AU (1) AU2015238300C1 (https=)
BR (1) BR112016022060B1 (https=)
CA (1) CA2943683A1 (https=)
CL (1) CL2016002382A1 (https=)
CR (1) CR20160501A (https=)
CY (1) CY1120969T1 (https=)
DK (1) DK3122742T3 (https=)
EA (1) EA032145B1 (https=)
ES (1) ES2702450T3 (https=)
HR (1) HRP20182073T1 (https=)
HU (1) HUE041738T2 (https=)
IL (1) IL247658B (https=)
JO (1) JO3512B1 (https=)
LT (1) LT3122742T (https=)
MA (1) MA39783B1 (https=)
MX (1) MX380829B (https=)
MY (1) MY194074A (https=)
NI (1) NI201600144A (https=)
NZ (1) NZ724907A (https=)
PH (1) PH12016501898B1 (https=)
PL (1) PL3122742T3 (https=)
PT (1) PT3122742T (https=)
RS (1) RS58088B1 (https=)
SG (1) SG11201607961QA (https=)
SI (1) SI3122742T1 (https=)
SM (1) SMT201800670T1 (https=)
TR (1) TR201819138T4 (https=)
TW (1) TWI686391B (https=)
UA (1) UA117958C2 (https=)
WO (1) WO2015144803A1 (https=)
ZA (1) ZA201606942B (https=)

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KR20240006494A (ko) * 2021-02-05 2024-01-15 블랙 다이아몬드 테라퓨틱스, 인코포레이티드 퀴녹살린 유도체 및 이의 사용

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