SE8007396L - Forfarande ocm medel for bestemning av en ligand i ett vetskemedium - Google Patents

Forfarande ocm medel for bestemning av en ligand i ett vetskemedium

Info

Publication number
SE8007396L
SE8007396L SE8007396A SE8007396A SE8007396L SE 8007396 L SE8007396 L SE 8007396L SE 8007396 A SE8007396 A SE 8007396A SE 8007396 A SE8007396 A SE 8007396A SE 8007396 L SE8007396 L SE 8007396L
Authority
SE
Sweden
Prior art keywords
conjugate
specific binding
liquid medium
ligand
bound
Prior art date
Application number
SE8007396A
Other languages
English (en)
Other versions
SE447510B (sv
Inventor
R C Boguslaski
R J Carrico
J E Christner
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of SE8007396L publication Critical patent/SE8007396L/sv
Publication of SE447510B publication Critical patent/SE447510B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531—Production of immunochemical test materials
    • G01N33/532—Production of labelled immunochemicals
    • G01N33/533—Production of labelled immunochemicals with fluorescent label

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • General Physics & Mathematics (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Saccharide Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)

Claims (1)

1. Testforfarande utnyttjande en specifik bindningsreaktion fir att i ett vatskemedium bestamma en ligand maid bland antigener och antikroppar dErtill; haptener och antikroppar dartill; hormoner, vitaminer, metaboliter och farmakologiska Tiedel saint deras receptorer Oct bindningssubstanser; mid vilket farfarande man (1) bringar vatskemediet i kontakt med ett reagens innefattande ett markt konjugat till bildning av en bunden form av del markta konjugatet och en fri form av dot markta konjugatet, varvid proportionerna mellan den bundna formen och den fria formen av Get markta konjugatet ar en funktion am koncentrationen av ligand i vatskemediet, vare'fter man (2) mdter mangden markningssubstans i den bundna formen eller den fra formen av dot mArkta konjugatet,kanneteeknat av att ett enzymsubstra anvandes sdsom markningssubstans.
SE8007396A 1975-04-28 1980-10-21 Forfarande och reagens for bestemning av en ligand i ett vetskemedium SE447510B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57200875A 1975-04-28 1975-04-28

Publications (2)

Publication Number Publication Date
SE8007396L true SE8007396L (sv) 1980-10-21
SE447510B SE447510B (sv) 1986-11-17

Family

ID=24285954

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7604841A SE440280B (sv) 1975-04-28 1976-04-27 Testforfarande och reagens med koenzymmerkning
SE8007396A SE447510B (sv) 1975-04-28 1980-10-21 Forfarande och reagens for bestemning av en ligand i ett vetskemedium
SE8007397A SE451895B (sv) 1975-04-28 1980-10-21 Kemiluminiscensforfarande for bestemning av en ligand i ett vetskemedium

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7604841A SE440280B (sv) 1975-04-28 1976-04-27 Testforfarande och reagens med koenzymmerkning

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8007397A SE451895B (sv) 1975-04-28 1980-10-21 Kemiluminiscensforfarande for bestemning av en ligand i ett vetskemedium

Country Status (23)

Country Link
JP (6) JPS6052378B2 (sv)
AT (1) AT357685B (sv)
AU (2) AU509182B2 (sv)
BE (1) BE841179A (sv)
BR (1) BR7602561A (sv)
CA (2) CA1078712A (sv)
CH (1) CH635438A5 (sv)
DD (1) DD125231A5 (sv)
DE (3) DE2618419C2 (sv)
DK (3) DK149969C (sv)
ES (1) ES447378A1 (sv)
FI (1) FI68324C (sv)
FR (1) FR2332533A1 (sv)
GB (2) GB1552607A (sv)
HU (1) HU179542B (sv)
IE (1) IE42544B1 (sv)
IL (1) IL49354A (sv)
IN (1) IN142734B (sv)
IT (1) IT1064132B (sv)
LU (1) LU74834A1 (sv)
NL (1) NL181281C (sv)
SE (3) SE440280B (sv)
ZA (1) ZA762030B (sv)

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DE2924249C2 (de) * 1978-06-22 1989-04-27 Miles, Inc., Elkhart, Ind., Us Spezifische bindungs-untersuchungsmethode zur bestimmung eines liganden in einem fluessigen medium und reagentien zur durchfuehrung dieser methode
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US4273866A (en) * 1979-02-05 1981-06-16 Abbott Laboratories Ligand analog-irreversible enzyme inhibitor conjugates and methods for use
GB2059421A (en) * 1979-10-03 1981-04-23 Self C H Assay method and reagents therefor
US4446231A (en) * 1979-10-03 1984-05-01 Self Colin H Immunoassay using an amplified cyclic detection system
US4259232A (en) * 1979-10-23 1981-03-31 Miles Laboratories, Inc. Flavin adenine dinucleotide-labeled protein and polypeptide conjugates
AT367796B (de) * 1979-10-29 1982-07-26 List Hans Verfahren zur bestimmung einer stoffkonzentration in einer loesung
WO1981001414A1 (en) * 1979-11-19 1981-05-28 Charles Hospital Dev An improved method of non homogenous enzyme immunoassay
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DK256581A (da) * 1980-06-13 1981-12-14 Nat Res Dev Bindingsanalyse
EP0049606A1 (en) * 1980-10-02 1982-04-14 Colin Henry Self Detection method, use and diagnostic aid
CA1183450A (en) * 1980-10-30 1985-03-05 Alfred C. Greenquist Homogeneous specific binding assay device and method
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CA1219824A (en) * 1981-04-17 1987-03-31 David C. Ward Modified nucleotides and methods of preparing and using same
ATE48140T1 (de) * 1981-04-17 1989-12-15 Univ Yale Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung.
US4711955A (en) * 1981-04-17 1987-12-08 Yale University Modified nucleotides and methods of preparing and using same
JPS5818167A (ja) * 1981-07-24 1983-02-02 Fuji Photo Film Co Ltd 分析フイルム及びこれを用いる分析方法
JPS5877843U (ja) * 1981-11-20 1983-05-26 株式会社三協精機製作所 テ−プレコ−ダ
GB2112779B (en) * 1981-12-11 1986-10-15 Welsh Nat School Med Aryl acridinium esters as luminescent labelling materials
FR2519005B1 (fr) * 1981-12-29 1985-10-25 Pasteur Institut Fragments d'adn marques a l'une au moins de leurs extremites par des ribonucleotides modifies reconnaissables par des molecules affines et procede pour realiser une analyse de tels fragments d'adn
FR2519004B1 (fr) * 1981-12-29 1985-09-27 Pasteur Institut Acide adenosine 5'-triphosphorique modifie et procede de dosage de substances biologiques susceptibles de fixer des produits de degradation de l'acide adenosine 5'-triphosphorique
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US5650270A (en) * 1982-02-01 1997-07-22 Northeastern University Molecular analytical release tags and their use in chemical analysis
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CA1223831A (en) * 1982-06-23 1987-07-07 Dean Engelhardt Modified nucleotides, methods of preparing and utilizing and compositions containing the same
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US4828979A (en) * 1984-11-08 1989-05-09 Life Technologies, Inc. Nucleotide analogs for nucleic acid labeling and detection
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Also Published As

Publication number Publication date
IT1064132B (it) 1985-02-18
DK150808C (da) 1988-02-15
SE451895B (sv) 1987-11-02
GB1552607A (en) 1979-09-19
DK576281A (da) 1981-12-23
JPS5951353A (ja) 1984-03-24
SE8007397L (sv) 1980-10-21
HU179542B (en) 1982-11-29
IE42544B1 (en) 1980-08-27
FI68324B (fi) 1985-04-30
IL49354A0 (en) 1976-06-30
ES447378A1 (es) 1977-11-01
ZA762030B (en) 1977-08-31
CA1078712A (en) 1980-06-03
JPS51146295A (en) 1976-12-15
DK158366C (da) 1990-10-01
DE2618419C2 (de) 1983-02-10
IN142734B (sv) 1977-08-20
AU502726B2 (en) 1979-08-09
BR7602561A (pt) 1976-11-23
CH635438A5 (en) 1983-03-31
JPS6052378B2 (ja) 1985-11-19
DE2660548C2 (de) 1984-04-12
DK576181A (da) 1981-12-23
FR2332533B1 (sv) 1981-12-18
FI761148A (sv) 1976-10-29
IL49354A (en) 1979-03-12
FR2332533A1 (fr) 1977-06-17
JPS604939B2 (ja) 1985-02-07
DD125231A5 (sv) 1977-04-06
SE440280B (sv) 1985-07-22
SE7604841L (sv) 1976-10-29
NL181281C (nl) 1987-07-16
AT357685B (de) 1980-07-25
DK189176A (da) 1976-10-29
AU509182B2 (en) 1980-04-24
JPS5951354A (ja) 1984-03-24
SE447510B (sv) 1986-11-17
DE2618511C3 (de) 1981-05-07
DE2618511A1 (de) 1976-11-04
DK149969B (da) 1986-11-03
JPS5267388A (en) 1977-06-03
DK150808B (da) 1987-06-22
DK158366B (da) 1990-05-07
GB1548741A (en) 1979-07-18
NL7604420A (nl) 1976-11-01
DE2618511B2 (de) 1980-08-14
AU1335376A (en) 1977-11-03
AU1335276A (en) 1977-11-03
JPH0145027B2 (sv) 1989-10-02
DE2618419A1 (de) 1976-11-04
IE42544L (en) 1976-10-28
NL181281B (nl) 1987-02-16
JPS5942454A (ja) 1984-03-09
JPH0137693B2 (sv) 1989-08-09
JPH0137694B2 (sv) 1989-08-09
CA1082577A (en) 1980-07-29
FI68324C (fi) 1985-08-12
JPS5942453A (ja) 1984-03-09
BE841179A (fr) 1976-08-16
LU74834A1 (sv) 1977-01-12
DK149969C (da) 1988-08-01
JPH0145026B2 (sv) 1989-10-02
ATA309376A (de) 1979-12-15

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