ES8700882A1 - Un metodo de inmuno ensayo heterogeneo con calibracion simultanea. - Google Patents
Un metodo de inmuno ensayo heterogeneo con calibracion simultanea.Info
- Publication number
- ES8700882A1 ES8700882A1 ES521948A ES521948A ES8700882A1 ES 8700882 A1 ES8700882 A1 ES 8700882A1 ES 521948 A ES521948 A ES 521948A ES 521948 A ES521948 A ES 521948A ES 8700882 A1 ES8700882 A1 ES 8700882A1
- Authority
- ES
- Spain
- Prior art keywords
- analyte
- binding
- calibration
- sample
- catalyst
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/542—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with steric inhibition or signal modification, e.g. fluorescent quenching
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
PROCEDIMIENTO DE INMUNOENSAYO HETEROGENEO CON CALIBRACION SIMULTANEA, EN ESENCIA UN METODO PARA DETERMINAR LA PREESENCIA, EN UNA MUESTRA, DE UN ANALITO QUE ES UNO DE LOS MIEMBROS DE UN PAR LIGADOR ESPECIFICO, CONSTITUIDO POR LIGANDO Y RECEPTOR. COMPRENDE LAS SIGUIENTES OPERACIONES: PRIMERA, SE EMPLEA UN MIP ETIQUETADO, UN SISTEMA PRODUCTOR DE SEÑAL Y UNA PRIMERA SUPERFICIE DE MEDICION, PARA REALIZAR UN ENSAYO ACUOSO EN UNA MUESTRA QUE CONTIENE EL ANALITO; SEGUNDA, SE DISPONE EN DICHO MEDIO DE ENSAYO UNA SEGUNDA SUPERFICIE DE CALIBRACION, LA CUAL PROPORCIONA UN NIVEL DE SEÑAL PROCEDENTE DEL COMPUESTO GENERADOR DE SEÑAL; Y POR ULTIMO, LA RELACION DE LA SEÑAL EN LA SEGUNDA SUPERFICIE, RESPECTO A LA SEÑAL EN LA PRIMERA SUPERFICIE, DEFINE LA CANTIDAD DE ANALITO EN LA MUESTRA. DE APLICACION EN LA DETECCION DE POLULANTES, CONTAMINANTES Y PRODUCTOS QUIMICOS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/374,849 US4533629A (en) | 1981-04-17 | 1982-05-04 | Simultaneous calibration heterogeneous immunoassay |
US06/399,107 US4540659A (en) | 1981-04-17 | 1982-07-16 | Simultaneous calibration heterogeneous immunoassay |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8700882A1 true ES8700882A1 (es) | 1986-02-01 |
ES521948A0 ES521948A0 (es) | 1986-02-01 |
Family
ID=27006800
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES521948A Expired ES8700882A1 (es) | 1982-05-04 | 1983-04-29 | Un metodo de inmuno ensayo heterogeneo con calibracion simultanea. |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0093613B1 (es) |
JP (1) | JP2651060B2 (es) |
AU (1) | AU560535B2 (es) |
BR (1) | BR8302286A (es) |
CA (1) | CA1193193A (es) |
DE (1) | DE3377744D1 (es) |
ES (1) | ES8700882A1 (es) |
HK (1) | HK96090A (es) |
IL (1) | IL68506A (es) |
SG (1) | SG78790G (es) |
Families Citing this family (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4743535A (en) * | 1984-11-07 | 1988-05-10 | Miles Inc. | Hybridization assay employing labeled probe and anti-hybrid |
EP0144914A3 (en) * | 1983-12-12 | 1986-08-13 | Miles Inc. | Hybridization assay employing labeled pairs of hybrid binding reagents |
IL73579A0 (en) * | 1983-12-12 | 1985-02-28 | Miles Lab | Hybridization assay employing labeled probe and antihybrid |
EP0144913A3 (en) * | 1983-12-12 | 1986-08-20 | Miles Inc. | Hybridization assay employing labeled probe and anti-hybrid |
FR2562252B1 (fr) * | 1984-03-27 | 1988-01-22 | Inst Nat Sante Rech Med | Procede de dosage immunoenzymatique sans etape de separation et reactifs et necessaires pour sa mise en oeuvre |
SE458643B (sv) * | 1984-12-07 | 1989-04-17 | Pharmacia Ab | Anordning med kolonnelement uppdelat i provparti och referenspatri |
GB2186078A (en) * | 1986-01-29 | 1987-08-05 | Iq | Method and apparatus for carrying out biochemical assay |
DE3609217A1 (de) * | 1986-03-19 | 1987-09-24 | Boehringer Mannheim Gmbh | Verfahren und reagenz zur bestimmung eines reaktionspartners einer immunologischen reaktion |
CA1291948C (en) * | 1986-04-24 | 1991-11-12 | Albert E. Chu | Variable volume assay device and method |
AU7385387A (en) * | 1986-06-09 | 1987-12-10 | Ortho Diagnostic Systems Inc. | Immunoassay using detection of colloidal gold |
AU602694B2 (en) * | 1986-06-09 | 1990-10-25 | Ortho Diagnostic Systems Inc. | Improved colloidal gold membrane assay |
EP0251707A1 (en) * | 1986-06-26 | 1988-01-07 | Ortho Diagnostic Systems Inc. | Methods for calibration of extended surface in homogeneous rate immunoassays |
CA1339006C (en) * | 1987-08-05 | 1997-03-25 | Howard B. Urnovitz | Self-contained multi-immunoassay diagnostic system |
US5447837A (en) * | 1987-08-05 | 1995-09-05 | Calypte, Inc. | Multi-immunoassay diagnostic system for antigens or antibodies or both |
JPH079069Y2 (ja) * | 1987-11-24 | 1995-03-06 | オムロン株式会社 | 生化学測定器のブランク値測定用反射板 |
CA1339723C (en) * | 1988-01-19 | 1998-03-17 | Philip Mcmahon | Immunoassay with multiple test spots |
GB2218200B (en) * | 1988-03-31 | 1992-01-29 | Cambridge Biomedical Limited | Test for analytes, using an immobilised binding partner, with washing step; and apparatus therefor. |
GB9025471D0 (en) * | 1990-11-22 | 1991-01-09 | Ares Serono Res & Dev Ltd | Method of assay |
US5726064A (en) * | 1990-11-22 | 1998-03-10 | Applied Research Systems Ars Holding Nv | Method of assay having calibration within the assay |
GB9212302D0 (en) * | 1992-06-10 | 1992-07-22 | Applied Research Systems | Method for improving measurement precision in evanescent wave optical biosensor assays |
GB9621256D0 (en) * | 1996-10-11 | 1996-11-27 | Xenova Ltd | Assay |
GB2335038B (en) * | 1996-10-11 | 2001-03-07 | Xenova Ltd | Double label immunoassay |
DE19838429C2 (de) * | 1998-08-24 | 2001-07-26 | Fraunhofer Ges Forschung | Anordnung zum schnellen Nachweis von mikrobiologischen oder biochemischen Stoffen |
CA2381495A1 (en) * | 1999-08-11 | 2001-02-22 | Unilever Plc | Internally referenced immunoassay and test device |
US6509196B1 (en) * | 2000-01-04 | 2003-01-21 | Response Biomedical Corp. | Compensation for non-specific signals in quantitative immunoassays |
AU2001274068A1 (en) | 2000-06-02 | 2001-12-11 | Zeptosens Ag | Kit and method for determining a plurality of analytes |
EP1493029B1 (en) | 2002-04-10 | 2010-03-31 | Response Biomedical Corporation | Sensitive immunochromatographic assay |
US7175992B2 (en) | 2002-04-10 | 2007-02-13 | Response Biomedical Corporation | Sensitive immunochromatographic assay |
EP2132571B1 (en) | 2007-02-26 | 2014-09-03 | Response Biomedical Corporation | Comparative multiple analyte assay |
WO2010115530A1 (de) | 2009-04-09 | 2010-10-14 | Bayer Cropscience Aktiengesellschaft | Vorrichtung und verfahren zum nachweis und zur quantitativen analyse von analyten insbesondere mykotoxinen |
EP3210630A1 (en) * | 2016-02-29 | 2017-08-30 | G.L. Pharma GmbH | Abuse-deterrent pharmaceutical compositions |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4294817A (en) * | 1977-11-25 | 1981-10-13 | International Diagnostic Technology, Inc. | Method of fluoro immunoassay |
US4163779A (en) * | 1978-01-09 | 1979-08-07 | International Diagnostic Technology, Inc. | Test for quantitation of immunoglobulin and identification of abnormal immunoglobulin |
JPS5833109Y2 (ja) * | 1978-08-25 | 1983-07-23 | 株式会社吉野工業所 | クリ−ム状フアンデ−シヨン用注出容器 |
US4299916A (en) * | 1979-12-26 | 1981-11-10 | Syva Company | Preferential signal production on a surface in immunoassays |
US4366241A (en) * | 1980-08-07 | 1982-12-28 | Syva Company | Concentrating zone method in heterogeneous immunoassays |
CA1209889A (en) * | 1981-09-18 | 1986-08-19 | Litai Weng | Homogeneous assay on a non-porous surface |
-
1983
- 1983-04-27 IL IL68506A patent/IL68506A/xx not_active IP Right Cessation
- 1983-04-29 ES ES521948A patent/ES8700882A1/es not_active Expired
- 1983-04-29 AU AU14110/83A patent/AU560535B2/en not_active Expired
- 1983-05-03 CA CA000427340A patent/CA1193193A/en not_active Expired
- 1983-05-03 DE DE19833377744 patent/DE3377744D1/de not_active Expired
- 1983-05-03 EP EP83302482A patent/EP0093613B1/en not_active Expired
- 1983-05-03 BR BR8302286A patent/BR8302286A/pt unknown
-
1990
- 1990-09-25 SG SG787/90A patent/SG78790G/en unknown
- 1990-11-15 HK HK960/90A patent/HK96090A/xx not_active IP Right Cessation
-
1991
- 1991-09-12 JP JP3261174A patent/JP2651060B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE3377744D1 (es) | 1988-09-22 |
AU1411083A (en) | 1983-11-10 |
IL68506A (en) | 1988-06-30 |
JP2651060B2 (ja) | 1997-09-10 |
EP0093613B1 (en) | 1988-08-17 |
ES521948A0 (es) | 1986-02-01 |
HK96090A (en) | 1990-11-23 |
EP0093613A1 (en) | 1983-11-09 |
JPH05209886A (ja) | 1993-08-20 |
CA1193193A (en) | 1985-09-10 |
BR8302286A (pt) | 1984-01-03 |
SG78790G (en) | 1990-11-23 |
IL68506A0 (en) | 1983-07-31 |
AU560535B2 (en) | 1987-04-09 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20050404 |