ATE48140T1 - Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung. - Google Patents

Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung.

Info

Publication number
ATE48140T1
ATE48140T1 AT82301804T AT82301804T ATE48140T1 AT E48140 T1 ATE48140 T1 AT E48140T1 AT 82301804 T AT82301804 T AT 82301804T AT 82301804 T AT82301804 T AT 82301804T AT E48140 T1 ATE48140 T1 AT E48140T1
Authority
AT
Austria
Prior art keywords
processes
production
compounds
applications include
modified nucleotides
Prior art date
Application number
AT82301804T
Other languages
English (en)
Inventor
David C Ward
Alexander A Waldrop Iii
Pennina R Langer
Original Assignee
Univ Yale
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Yale filed Critical Univ Yale
Priority claimed from EP82301804A external-priority patent/EP0063879B1/de
Application granted granted Critical
Publication of ATE48140T1 publication Critical patent/ATE48140T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804Nucleic acid analysis using immunogens
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813Hybridisation assays
    • C12Q1/6816Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT82301804T 1981-04-17 1982-04-06 Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung. ATE48140T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25522381A 1981-04-17 1981-04-17
EP82301804A EP0063879B1 (de) 1981-04-17 1982-04-06 Modifizierte Nukleotide und Verfahren zu ihrer Herstellung und Anwendung

Publications (1)

Publication Number Publication Date
ATE48140T1 true ATE48140T1 (de) 1989-12-15

Family

ID=26085237

Family Applications (1)

Application Number Title Priority Date Filing Date
AT82301804T ATE48140T1 (de) 1981-04-17 1982-04-06 Modifizierte nukleotide und verfahren zu ihrer herstellung und anwendung.

Country Status (2)

Country Link
EP (1) EP0329198B1 (de)
AT (1) ATE48140T1 (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5681726A (en) * 1988-09-19 1997-10-28 Stratagene Method of double stranded DNA synthesis
FR2780059B1 (fr) 1998-06-17 2002-10-11 Bio Merieux Procede de marquage d'un acide ribonucleique et fragments d'arn marques ainsi obtenus
US6902891B2 (en) 1999-12-17 2005-06-07 Bio Merieux Process for labeling a nucleic acid
US6489114B2 (en) 1999-12-17 2002-12-03 Bio Merieux Process for labeling a ribonucleic acid, and labeled RNA fragments which are obtained thereby
US7060441B2 (en) 2001-05-04 2006-06-13 Biomerieux Method for fragmenting and labeling DNA involving abasic sites and phosphate labeling
FR2868071B1 (fr) 2004-03-26 2006-06-09 Biomerieux Sa Reactifs de marquage, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
FR2886735B1 (fr) 2005-06-01 2015-09-11 Biomerieux Sa Procede de marquage ou de traitement d'un echantillon biologique contenant des molecules biologiques d'interet, notamment des acides nucleiques
FR2917090B1 (fr) 2007-06-11 2012-06-15 Biomerieux Sa Reactifs de marquage portant des fonctions diazo et nitro, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
FR2934595B1 (fr) 2008-07-29 2013-04-05 Biomerieux Sa Reactifs de marquage ayant un noyau pyridine portant une fonction diazomethyle, procedes de synthese de tels reactifs et procedes de detection de molecules biologiques
EP2390350A1 (de) 2010-05-27 2011-11-30 Centre National de la Recherche Scientifique (CNRS) Verfahren zur DNA-Sequenzierung durch Polymerisation
EP2390351A1 (de) 2010-05-27 2011-11-30 Centre National de la Recherche Scientifique (CNRS) Verfahren zur DNA-Sequenzierung durch Hybridisierung
FR2968302B1 (fr) 2010-12-06 2012-11-30 Biomerieux Sa Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
AU2012356826B2 (en) 2011-12-22 2017-08-17 Centre National De La Recherche Scientifique (Cnrs) Method of DNA detection and quantification by single-molecule hybridization and manipulation
FR2994184B1 (fr) 2012-08-02 2017-12-08 Biomerieux Sa Procedes de fonctionalisation et reactifs utilises dans de tels procedes utilisant un anhydride aza-isatoique ou un de ses derives, molecules biologiques ainsi traitees et kits
ES2689676T3 (es) 2013-01-22 2018-11-15 Centre National De La Recherche Scientifique (Cnrs) Procedimiento para la detección de modificaciones de ADN por manipulación de una sola molécula
CN107771222B (zh) 2015-05-07 2019-06-04 巴黎科学与文学联大-拉丁区 使用力诱导的链侵入原位形成发夹
AU2018306910A1 (en) * 2017-07-24 2020-02-20 Rohm And Haas Company Chloride-free cationic polymers using acetate anions
FR3075820B1 (fr) 2017-12-21 2022-12-30 Paris Sciences Lettres Quartier Latin Molecule d'adn double-brin pour la detection et la caracterisation des interactions moleculaires

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN142734B (de) * 1975-04-28 1977-08-20 Miles Lab
FR2422956A1 (fr) * 1978-04-13 1979-11-09 Pasteur Institut Procede de detection et de caracterisation d'un acide nucleique ou d'une sequence de celui-ci, et reactif enzymatique pour la mise en oeuvre de ce procede

Also Published As

Publication number Publication date
EP0329198A2 (de) 1989-08-23
EP0329198B1 (de) 1998-06-10
EP0329198A3 (de) 1991-03-27

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
EELA Cancelled due to lapse of time