DE3280478D1 - Basenmodifizierte Oligo- und Polynucleotide und Verfahren zu ihrer Herstellung und Verwendung - Google Patents

Basenmodifizierte Oligo- und Polynucleotide und Verfahren zu ihrer Herstellung und Verwendung

Info

Publication number
DE3280478D1
DE3280478D1 DE3280478T DE3280478T DE3280478D1 DE 3280478 D1 DE3280478 D1 DE 3280478D1 DE 3280478 T DE3280478 T DE 3280478T DE 3280478 T DE3280478 T DE 3280478T DE 3280478 D1 DE3280478 D1 DE 3280478D1
Authority
DE
Germany
Prior art keywords
deazapurine
purine
attached
pyrimidine
linkage
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE3280478T
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English (en)
Other versions
DE3280478T2 (de
Inventor
David C Ward
Alexander A Waldrop
Pennina R Langer
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yale University
Original Assignee
Yale University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22967380&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3280478(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Yale University filed Critical Yale University
Publication of DE3280478D1 publication Critical patent/DE3280478D1/de
Application granted granted Critical
Publication of DE3280478T2 publication Critical patent/DE3280478T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/02—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving viable microorganisms
    • C12Q1/18—Testing for antimicrobial activity of a material
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6804—Nucleic acid analysis using immunogens
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6816—Hybridisation assays characterised by the detection means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Saccharide Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE3280478T 1981-04-17 1982-04-06 Basenmodifizierte Oligo- und Polynucleotide und Verfahren zu ihrer Herstellung und Verwendung Expired - Lifetime DE3280478T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US25522381A 1981-04-17 1981-04-17

Publications (2)

Publication Number Publication Date
DE3280478D1 true DE3280478D1 (de) 1998-07-16
DE3280478T2 DE3280478T2 (de) 1999-02-18

Family

ID=22967380

Family Applications (2)

Application Number Title Priority Date Filing Date
DE8282301804T Expired DE3280032D1 (en) 1981-04-17 1982-04-06 Modified nucleotides and methods of preparing and using same
DE3280478T Expired - Lifetime DE3280478T2 (de) 1981-04-17 1982-04-06 Basenmodifizierte Oligo- und Polynucleotide und Verfahren zu ihrer Herstellung und Verwendung

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE8282301804T Expired DE3280032D1 (en) 1981-04-17 1982-04-06 Modified nucleotides and methods of preparing and using same

Country Status (8)

Country Link
EP (1) EP0063879B1 (de)
JP (6) JPS57209297A (de)
AT (1) ATE167189T1 (de)
AU (1) AU560651B2 (de)
CA (1) CA1219824A (de)
DE (2) DE3280032D1 (de)
DK (3) DK164407B (de)
IL (1) IL65447A (de)

Families Citing this family (186)

* Cited by examiner, † Cited by third party
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JPH0880B2 (ja) 1996-01-10
DK171382A (da) 1982-10-18
AU8257382A (en) 1982-10-21
EP0063879A3 (en) 1983-08-10
ATE167189T1 (de) 1998-06-15
DK46797A (da) 1997-04-28
AU560651B2 (en) 1987-04-16
DE3280478T2 (de) 1999-02-18
DE3280032D1 (en) 1989-12-28
DK171822B1 (da) 1997-06-23
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JPH07107998A (ja) 1995-04-25
JPS6399093A (ja) 1988-04-30
EP0063879A2 (de) 1982-11-03
CA1219824A (en) 1987-03-31
IL65447A (en) 1987-01-30
IL65447A0 (en) 1982-07-30
JPH1033199A (ja) 1998-02-10
JP3279502B2 (ja) 2002-04-30
DK160591A (da) 1991-09-16
JP3279503B2 (ja) 2002-04-30
JPH03261798A (ja) 1991-11-21
EP0063879B1 (de) 1989-11-23
JPH0375559B2 (de) 1991-12-02

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