SE446003B - Mellanprodukter for framstellning av hydroxiaminoeburnanderivat - Google Patents

Mellanprodukter for framstellning av hydroxiaminoeburnanderivat

Info

Publication number
SE446003B
SE446003B SE8004079A SE8004079A SE446003B SE 446003 B SE446003 B SE 446003B SE 8004079 A SE8004079 A SE 8004079A SE 8004079 A SE8004079 A SE 8004079A SE 446003 B SE446003 B SE 446003B
Authority
SE
Sweden
Prior art keywords
ethyl
indolo
octahydro
acid
general formula
Prior art date
Application number
SE8004079A
Other languages
English (en)
Swedish (sv)
Other versions
SE8004079L (sv
Inventor
C Szantay
L Szabo
G Kalaus
J Sapi
L Dancsi
T Keve
M Gazdag
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of SE8004079L publication Critical patent/SE8004079L/xx
Publication of SE446003B publication Critical patent/SE446003B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
SE8004079A 1979-05-31 1980-05-30 Mellanprodukter for framstellning av hydroxiaminoeburnanderivat SE446003B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79RI713A HU181495B (en) 1979-05-31 1979-05-31 Process for producing hydroxy-imino-eburnane derivatives

Publications (2)

Publication Number Publication Date
SE8004079L SE8004079L (sv) 1980-12-01
SE446003B true SE446003B (sv) 1986-08-04

Family

ID=11001097

Family Applications (2)

Application Number Title Priority Date Filing Date
SE8004079A SE446003B (sv) 1979-05-31 1980-05-30 Mellanprodukter for framstellning av hydroxiaminoeburnanderivat
SE8501069A SE461653B (sv) 1979-05-31 1985-03-05 Foerfarande foer framstaellning av aminoeburnanderivat

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE8501069A SE461653B (sv) 1979-05-31 1985-03-05 Foerfarande foer framstaellning av aminoeburnanderivat

Country Status (26)

Country Link
US (1) US4345082A (da)
JP (1) JPS55162784A (da)
AT (1) AT373252B (da)
AU (1) AU540977B2 (da)
BE (1) BE883576A (da)
CA (1) CA1148157A (da)
CH (1) CH646970A5 (da)
DD (2) DD201592A5 (da)
DE (1) DE3020695A1 (da)
DK (1) DK153149C (da)
ES (4) ES491992A0 (da)
FI (1) FI801757A (da)
FR (2) FR2457867A1 (da)
GB (2) GB2072660B (da)
GR (1) GR68469B (da)
HU (1) HU181495B (da)
IL (1) IL60058A (da)
IT (1) IT1147741B (da)
NL (1) NL8002959A (da)
NO (2) NO801627L (da)
NZ (1) NZ193795A (da)
PT (1) PT71328A (da)
SE (2) SE446003B (da)
SU (2) SU927116A3 (da)
YU (1) YU145480A (da)
ZA (1) ZA802888B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446139A (en) * 1979-05-31 1984-05-01 Richter Gedeon Vegyeszeti Gyar R.T. Hexahydroindoloquinolizinium and octahydroindoloquinolizine esters, and method of increasing blood flow in an animal with hydroxyamino-eburnane derivatives
HU183207B (en) * 1980-09-10 1984-04-28 Richter Gedeon Vegyeszet Process for preparing apovincaminic acid esters
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
HU191403B (en) * 1984-04-02 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing new, raceme and optically active 14-hydroxyimino-eburnane
IT1248882B (it) * 1989-06-21 1995-01-30 Richter Gedeon Vegyeszet Derivati diesteri di ottaidro-indolo/2,3-a/chinolizina e loro sali nonche' procedimento per la loro preparazione
JP2851133B2 (ja) * 1989-06-21 1999-01-27 リヒター ゲデオン ベジェセティ ジャール アール．テー． 新規ラセミ及び光学的活性オクタヒドロ―インド―ロ〔２，３―ａ〕テトラヒドロピラニル〔２，３―ｃ〕キノリジンジエステル誘導体及びその調製方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU163143B (da) * 1971-05-07 1973-06-28
US4035370A (en) * 1971-11-03 1977-07-12 Richter Gedeon Vegyeszeti Gyar Rt. Alkaloid esters
HU172068B (hu) * 1975-06-13 1978-05-28 Richter Gedeon Vegyeszet Sposob asimmetricheskogo sinteza oktagidro-indolo/2,3-a/ khinolizidinov
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
HU175527B (hu) * 1977-03-28 1980-08-28 Richter Gedeon Vegyeszet Sposob dlja totalsinteze slozhnykh efirov apovinkaminnojj kisloty i gomologov
HU180514B (hu) * 1977-05-26 1983-03-28 Richter Gedeon Vegyeszet Eljárás apovinkaminsav-észterek, illetve vinkaminsav-észterek és apovinkaminsavészterek egyidejű előállítására
FR2398746A1 (fr) * 1977-07-25 1979-02-23 Roussel Uclaf Nouveaux derives d'alcaloides pentacycliques, leur procede de preparation, leur application comme medicaments, et leur application a la synthese de produits du groupe de l'eburnamonine

Also Published As

Publication number Publication date
GB2051794B (en) 1983-04-27
IL60058A (en) 1984-06-29
GB2072660A (en) 1981-10-07
ES8105731A1 (es) 1981-06-01
ES499286A0 (es) 1982-06-01
SE8004079L (sv) 1980-12-01
US4345082A (en) 1982-08-17
ES499288A0 (es) 1982-01-01
AU540977B2 (en) 1984-12-13
BE883576A (fr) 1980-12-01
FI801757A (fi) 1980-12-01
DD151939A5 (de) 1981-11-11
NO801627L (no) 1980-12-01
HU181495B (en) 1983-07-28
NZ193795A (en) 1983-05-10
ES8202007A1 (es) 1982-01-01
PT71328A (en) 1980-06-01
DK232080A (da) 1980-12-01
GR68469B (da) 1982-01-04
YU145480A (en) 1984-02-29
AT373252B (de) 1984-01-10
FR2457867A1 (fr) 1980-12-26
FR2457867B1 (da) 1983-07-22
CH646970A5 (de) 1984-12-28
ES491992A0 (es) 1981-06-01
SU1005663A3 (ru) 1983-03-15
CA1148157A (en) 1983-06-14
FR2479828A1 (da) 1981-10-09
NO852308L (no) 1980-12-01
DK153149C (da) 1988-10-31
IL60058A0 (en) 1980-07-31
DE3020695C2 (da) 1991-05-16
FR2479828B1 (da) 1983-03-04
SE8501069D0 (sv) 1985-03-05
ES499287A0 (es) 1982-01-01
ES8202008A1 (es) 1982-01-01
ES8205411A1 (es) 1982-06-01
IT8067826A0 (it) 1980-05-27
IT1147741B (it) 1986-11-26
DD201592A5 (de) 1983-07-27
GB2072660B (en) 1983-10-26
DK153149B (da) 1988-06-20
JPS55162784A (en) 1980-12-18
SU927116A3 (ru) 1982-05-07
SE461653B (sv) 1990-03-12
GB2051794A (en) 1981-01-21
JPH0142952B2 (da) 1989-09-18
NL8002959A (nl) 1980-12-02
AU5892180A (en) 1980-12-04
ATA287880A (de) 1983-05-15
DE3020695A1 (de) 1980-12-11
ZA802888B (en) 1981-07-29

Similar Documents

Publication Publication Date Title
JP2558086B2 (ja) 縮合ピリジン化合物類の製造方法
HU218488B (hu) Új eljárás imidazo-piridin-származékok előállítására
US7923558B2 (en) Method for obtaining pure tetrahydrocannabinol
SU460626A3 (ru) Способ получени винкамина или его производных
HU195182B (en) Process for production of /z/-1-phenil-1-diethil-amino-carbonil-2-amino-methil-cyclopropan hcl
FR2458544A1 (fr) Nouveaux amides d'acide pyrrolidin-(2)-on-(1)-ylalcoyl-carboxylique, leur procede de preparation et leur application comme medicaments
EP0314280B1 (en) Process for the preparation of fused pyridine compounds
SE446003B (sv) Mellanprodukter for framstellning av hydroxiaminoeburnanderivat
SU481155A3 (ru) Способ получени -(фурил-метил)морфинанов
SU698532A3 (ru) Способ получени производных пиридо (1,2-а) пиримидина
SU479290A3 (ru) Способ получени 2-(фурилметил)-6,7бензоморфанов
SE435622B (sv) Terapeutisk komposition innehallande indolo(2,3-a)kinolizidiner
ES2229688T3 (es) Derivados de 3,4-dihidroxi-quinolina como agentes inhibidores de la monoxido de nitrogeno sintasa (nos).
WO2002022618A1 (fr) Preparation de la camptothecine et de ses derives
GB2036744A (en) Eburnane derivatives
JPH0635458B2 (ja) ピリドンカルボン酸誘導体、そのエステルおよびその塩
FI73429C (fi) Som mellanprodukt vid framstaellning av terapeutiskt anvaendbara hydroxiamino-eburnanderivat anvaendbara indolokinolizinderivat.
US2762804A (en) 3-methyl-5-phenyl-2, 6-piperazinedione and derivatives thereof and method of preparing same
US6426417B1 (en) Processes and intermediates useful to make antifolates
HU223138B1 (hu) Új eljárás racém alkil-4,6,7,8,9,9a-hexahidro-2H, 3H-pirido-[1,2-a] pirazin-1-on-7-karbonsavészterek előállítására
JPH0674260B2 (ja) キノリン誘導体、そのエステルおよびその塩
JPH0358340B2 (da)
SU328572A1 (ru) СПОСОБ ПОЛУЧЕНИЯ АМИДОВ ИЛИ ПЕПТИДОВ N-АЦИЛ-а-АМИНОКИСЛОТЫ
SU1189351A3 (ru) Способ получени 5 @ -/2 @ -бутил/-пептидэрготалкалоида или его аддитивных солей с кислотами
US3303195A (en) Methylated deserpidine

Legal Events

Date Code Title Description
NAL Patent in force

Ref document number: 8004079-3

Format of ref document f/p: F

NUG Patent has lapsed

Ref document number: 8004079-3

Format of ref document f/p: F