DK153149C - Analogifremgangsmaade til fremstilling af hydroxyaminoeburnanderivater eller farmaceutisk acceptable syreadditionssalte eller optisk aktiv isomerer deraf, samt octahydroindolokinolizin-monoesterderivater til anvendelse som udgangsmateriale ved fremgangsmaaden - Google Patents

Analogifremgangsmaade til fremstilling af hydroxyaminoeburnanderivater eller farmaceutisk acceptable syreadditionssalte eller optisk aktiv isomerer deraf, samt octahydroindolokinolizin-monoesterderivater til anvendelse som udgangsmateriale ved fremgangsmaaden

Info

Publication number
DK153149C
DK153149C DK232080A DK232080A DK153149C DK 153149 C DK153149 C DK 153149C DK 232080 A DK232080 A DK 232080A DK 232080 A DK232080 A DK 232080A DK 153149 C DK153149 C DK 153149C
Authority
DK
Denmark
Prior art keywords
derivated
isomerated
hydroxyaminoeburnand
anosterives
anosterane
Prior art date
Application number
DK232080A
Other languages
English (en)
Other versions
DK153149B (da
DK232080A (da
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Janos Sapi
Lajos Dancsi
Tibor Keve
Maria Gazdag
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK232080A publication Critical patent/DK232080A/da
Publication of DK153149B publication Critical patent/DK153149B/da
Application granted granted Critical
Publication of DK153149C publication Critical patent/DK153149C/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D461/00—Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
DK232080A 1979-05-31 1980-05-29 Analogifremgangsmaade til fremstilling af hydroxyaminoeburnanderivater eller farmaceutisk acceptable syreadditionssalte eller optisk aktiv isomerer deraf, samt octahydroindolokinolizin-monoesterderivater til anvendelse som udgangsmateriale ved fremgangsmaaden DK153149C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU79RI713A HU181495B (en) 1979-05-31 1979-05-31 Process for producing hydroxy-imino-eburnane derivatives
HURI000713 1979-05-31

Publications (3)

Publication Number Publication Date
DK232080A DK232080A (da) 1980-12-01
DK153149B DK153149B (da) 1988-06-20
DK153149C true DK153149C (da) 1988-10-31

Family

ID=11001097

Family Applications (1)

Application Number Title Priority Date Filing Date
DK232080A DK153149C (da) 1979-05-31 1980-05-29 Analogifremgangsmaade til fremstilling af hydroxyaminoeburnanderivater eller farmaceutisk acceptable syreadditionssalte eller optisk aktiv isomerer deraf, samt octahydroindolokinolizin-monoesterderivater til anvendelse som udgangsmateriale ved fremgangsmaaden

Country Status (26)

Country Link
US (1) US4345082A (da)
JP (1) JPS55162784A (da)
AT (1) AT373252B (da)
AU (1) AU540977B2 (da)
BE (1) BE883576A (da)
CA (1) CA1148157A (da)
CH (1) CH646970A5 (da)
DD (2) DD201592A5 (da)
DE (1) DE3020695A1 (da)
DK (1) DK153149C (da)
ES (4) ES491992A0 (da)
FI (1) FI801757A (da)
FR (2) FR2457867A1 (da)
GB (2) GB2051794B (da)
GR (1) GR68469B (da)
HU (1) HU181495B (da)
IL (1) IL60058A (da)
IT (1) IT1147741B (da)
NL (1) NL8002959A (da)
NO (2) NO801627L (da)
NZ (1) NZ193795A (da)
PT (1) PT71328A (da)
SE (2) SE446003B (da)
SU (2) SU927116A3 (da)
YU (1) YU145480A (da)
ZA (1) ZA802888B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446139A (en) * 1979-05-31 1984-05-01 Richter Gedeon Vegyeszeti Gyar R.T. Hexahydroindoloquinolizinium and octahydroindoloquinolizine esters, and method of increasing blood flow in an animal with hydroxyamino-eburnane derivatives
HU183207B (en) * 1980-09-10 1984-04-28 Richter Gedeon Vegyeszet Process for preparing apovincaminic acid esters
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
HU191403B (en) * 1984-04-02 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing new, raceme and optically active 14-hydroxyimino-eburnane
JP2922260B2 (ja) * 1989-06-21 1999-07-19 リヒター ゲデオン ベジェセティ ジャール アール．テー． 新規オクタヒドロ―インドーロ〔２，３―ａ〕キノリジンジエステル誘導体及びその塩並びにそれらの調製方法
IT1248881B (it) * 1989-06-21 1995-01-30 Richter Gedeon Vegyeszet Derivati diesteri di ottaidro-indolo/2,3-a/tetraidropiramil/2,3-c/ chinolizina racemici ed otticamente attivi e procedimento per la loro preparazione

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU163143B (da) * 1971-05-07 1973-06-28
US4035370A (en) * 1971-11-03 1977-07-12 Richter Gedeon Vegyeszeti Gyar Rt. Alkaloid esters
HU172068B (hu) * 1975-06-13 1978-05-28 Richter Gedeon Vegyeszet Sposob asimmetricheskogo sinteza oktagidro-indolo/2,3-a/ khinolizidinov
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
HU175527B (hu) * 1977-03-28 1980-08-28 Richter Gedeon Vegyeszet Sposob dlja totalsinteze slozhnykh efirov apovinkaminnojj kisloty i gomologov
HU180514B (hu) * 1977-05-26 1983-03-28 Richter Gedeon Vegyeszet Eljárás apovinkaminsav-észterek, illetve vinkaminsav-észterek és apovinkaminsavészterek egyidejű előállítására
FR2398746A1 (fr) * 1977-07-25 1979-02-23 Roussel Uclaf Nouveaux derives d'alcaloides pentacycliques, leur procede de preparation, leur application comme medicaments, et leur application a la synthese de produits du groupe de l'eburnamonine

Also Published As

Publication number Publication date
IL60058A (en) 1984-06-29
AU540977B2 (en) 1984-12-13
ES8105731A1 (es) 1981-06-01
BE883576A (fr) 1980-12-01
ES491992A0 (es) 1981-06-01
DK153149B (da) 1988-06-20
CH646970A5 (de) 1984-12-28
ES8202008A1 (es) 1982-01-01
SE8501069D0 (sv) 1985-03-05
YU145480A (en) 1984-02-29
NL8002959A (nl) 1980-12-02
AU5892180A (en) 1980-12-04
JPS55162784A (en) 1980-12-18
GB2051794B (en) 1983-04-27
SU1005663A3 (ru) 1983-03-15
DE3020695C2 (da) 1991-05-16
FR2457867B1 (da) 1983-07-22
IL60058A0 (en) 1980-07-31
GB2072660B (en) 1983-10-26
SE446003B (sv) 1986-08-04
DK232080A (da) 1980-12-01
DE3020695A1 (de) 1980-12-11
GB2051794A (en) 1981-01-21
PT71328A (en) 1980-06-01
AT373252B (de) 1984-01-10
IT8067826A0 (it) 1980-05-27
ES499286A0 (es) 1982-06-01
ATA287880A (de) 1983-05-15
SU927116A3 (ru) 1982-05-07
FI801757A (fi) 1980-12-01
NO852308L (no) 1980-12-01
DD201592A5 (de) 1983-07-27
CA1148157A (en) 1983-06-14
FR2457867A1 (fr) 1980-12-26
SE8004079L (sv) 1980-12-01
ES499288A0 (es) 1982-01-01
NO801627L (no) 1980-12-01
HU181495B (en) 1983-07-28
GR68469B (da) 1982-01-04
ES499287A0 (es) 1982-01-01
US4345082A (en) 1982-08-17
NZ193795A (en) 1983-05-10
FR2479828A1 (da) 1981-10-09
SE461653B (sv) 1990-03-12
FR2479828B1 (da) 1983-03-04
ZA802888B (en) 1981-07-29
ES8202007A1 (es) 1982-01-01
ES8205411A1 (es) 1982-06-01
GB2072660A (en) 1981-10-07
JPH0142952B2 (da) 1989-09-18
IT1147741B (it) 1986-11-26
DD151939A5 (de) 1981-11-11

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