ZA802888B - New hydroxyamino-eburnane derivatives and a process for the preparation thereof - Google Patents

New hydroxyamino-eburnane derivatives and a process for the preparation thereof

Info

Publication number
ZA802888B
ZA802888B ZA00802888A ZA802888A ZA802888B ZA 802888 B ZA802888 B ZA 802888B ZA 00802888 A ZA00802888 A ZA 00802888A ZA 802888 A ZA802888 A ZA 802888A ZA 802888 B ZA802888 B ZA 802888B
Authority
ZA
South Africa
Prior art keywords
hydroxyamino
preparation
new
eburnane derivatives
eburnane
Prior art date
Application number
ZA00802888A
Other languages
English (en)
Inventor
M Gazdag
L Dancsi
L Szabo
J Sapi
Csaba Szantay
Szantay Csaba
G Kalaus
T Keve
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of ZA802888B publication Critical patent/ZA802888B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D461/00Heterocyclic compounds containing indolo [3,2,1-d,e] pyrido [3,2,1,j] [1,5]-naphthyridine ring systems, e.g. vincamine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Cephalosporin Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
ZA00802888A 1979-05-31 1980-05-14 New hydroxyamino-eburnane derivatives and a process for the preparation thereof ZA802888B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU79RI713A HU181495B (en) 1979-05-31 1979-05-31 Process for producing hydroxy-imino-eburnane derivatives

Publications (1)

Publication Number Publication Date
ZA802888B true ZA802888B (en) 1981-07-29

Family

ID=11001097

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA00802888A ZA802888B (en) 1979-05-31 1980-05-14 New hydroxyamino-eburnane derivatives and a process for the preparation thereof

Country Status (26)

Country Link
US (1) US4345082A (da)
JP (1) JPS55162784A (da)
AT (1) AT373252B (da)
AU (1) AU540977B2 (da)
BE (1) BE883576A (da)
CA (1) CA1148157A (da)
CH (1) CH646970A5 (da)
DD (2) DD201592A5 (da)
DE (1) DE3020695A1 (da)
DK (1) DK153149C (da)
ES (4) ES491992A0 (da)
FI (1) FI801757A (da)
FR (2) FR2457867A1 (da)
GB (2) GB2072660B (da)
GR (1) GR68469B (da)
HU (1) HU181495B (da)
IL (1) IL60058A (da)
IT (1) IT1147741B (da)
NL (1) NL8002959A (da)
NO (2) NO801627L (da)
NZ (1) NZ193795A (da)
PT (1) PT71328A (da)
SE (2) SE446003B (da)
SU (2) SU927116A3 (da)
YU (1) YU145480A (da)
ZA (1) ZA802888B (da)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4446139A (en) * 1979-05-31 1984-05-01 Richter Gedeon Vegyeszeti Gyar R.T. Hexahydroindoloquinolizinium and octahydroindoloquinolizine esters, and method of increasing blood flow in an animal with hydroxyamino-eburnane derivatives
HU183207B (en) * 1980-09-10 1984-04-28 Richter Gedeon Vegyeszet Process for preparing apovincaminic acid esters
HU183234B (en) * 1980-10-17 1984-04-28 Richter Gedeon Vegyeszet Process for the enantioselective synthesis of optically active cys-14-oxo-e-homo-eburnan
HU182411B (en) * 1981-11-03 1984-01-30 Richter Gedeon Vegyeszet Process for preparing eburnamonine derivatives
HU186891B (en) * 1981-06-12 1985-10-28 Richter Gedeon Vegyeszet Process for producing esters of apovincaminic acid
HU182380B (en) * 1981-09-30 1983-12-28 Richter Gedeon Vegyeszet Process for producing esters of vincaminic acid
HU191403B (en) * 1984-04-02 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt,Hu Process for preparing new, raceme and optically active 14-hydroxyimino-eburnane
IT1248882B (it) * 1989-06-21 1995-01-30 Richter Gedeon Vegyeszet Derivati diesteri di ottaidro-indolo/2,3-a/chinolizina e loro sali nonche' procedimento per la loro preparazione
JP2851133B2 (ja) * 1989-06-21 1999-01-27 リヒター ゲデオン ベジェセティ ジャール アール.テー. 新規ラセミ及び光学的活性オクタヒドロ―インド―ロ〔2,3―a〕テトラヒドロピラニル〔2,3―c〕キノリジンジエステル誘導体及びその調製方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU163143B (da) * 1971-05-07 1973-06-28
US4035370A (en) * 1971-11-03 1977-07-12 Richter Gedeon Vegyeszeti Gyar Rt. Alkaloid esters
HU172068B (hu) * 1975-06-13 1978-05-28 Richter Gedeon Vegyeszet Sposob asimmetricheskogo sinteza oktagidro-indolo/2,3-a/ khinolizidinov
HU174502B (hu) * 1976-12-30 1980-01-28 Richter Gedeon Vegyeszet Sposob poluchenija novykh proizvodnykh oktagidro-indolo/2,3-a/-khinolizina
HU175527B (hu) * 1977-03-28 1980-08-28 Richter Gedeon Vegyeszet Sposob dlja totalsinteze slozhnykh efirov apovinkaminnojj kisloty i gomologov
HU180514B (hu) * 1977-05-26 1983-03-28 Richter Gedeon Vegyeszet Eljárás apovinkaminsav-észterek, illetve vinkaminsav-észterek és apovinkaminsavészterek egyidejű előállítására
FR2398746A1 (fr) * 1977-07-25 1979-02-23 Roussel Uclaf Nouveaux derives d'alcaloides pentacycliques, leur procede de preparation, leur application comme medicaments, et leur application a la synthese de produits du groupe de l'eburnamonine

Also Published As

Publication number Publication date
GB2051794B (en) 1983-04-27
IL60058A (en) 1984-06-29
GB2072660A (en) 1981-10-07
ES8105731A1 (es) 1981-06-01
ES499286A0 (es) 1982-06-01
SE8004079L (sv) 1980-12-01
US4345082A (en) 1982-08-17
ES499288A0 (es) 1982-01-01
AU540977B2 (en) 1984-12-13
BE883576A (fr) 1980-12-01
FI801757A (fi) 1980-12-01
DD151939A5 (de) 1981-11-11
NO801627L (no) 1980-12-01
HU181495B (en) 1983-07-28
NZ193795A (en) 1983-05-10
ES8202007A1 (es) 1982-01-01
PT71328A (en) 1980-06-01
DK232080A (da) 1980-12-01
GR68469B (da) 1982-01-04
YU145480A (en) 1984-02-29
AT373252B (de) 1984-01-10
FR2457867A1 (fr) 1980-12-26
FR2457867B1 (da) 1983-07-22
CH646970A5 (de) 1984-12-28
ES491992A0 (es) 1981-06-01
SE446003B (sv) 1986-08-04
SU1005663A3 (ru) 1983-03-15
CA1148157A (en) 1983-06-14
FR2479828A1 (da) 1981-10-09
NO852308L (no) 1980-12-01
DK153149C (da) 1988-10-31
IL60058A0 (en) 1980-07-31
DE3020695C2 (da) 1991-05-16
FR2479828B1 (da) 1983-03-04
SE8501069D0 (sv) 1985-03-05
ES499287A0 (es) 1982-01-01
ES8202008A1 (es) 1982-01-01
ES8205411A1 (es) 1982-06-01
IT8067826A0 (it) 1980-05-27
IT1147741B (it) 1986-11-26
DD201592A5 (de) 1983-07-27
GB2072660B (en) 1983-10-26
DK153149B (da) 1988-06-20
JPS55162784A (en) 1980-12-18
SU927116A3 (ru) 1982-05-07
SE461653B (sv) 1990-03-12
GB2051794A (en) 1981-01-21
JPH0142952B2 (da) 1989-09-18
NL8002959A (nl) 1980-12-02
AU5892180A (en) 1980-12-04
ATA287880A (de) 1983-05-15
DE3020695A1 (de) 1980-12-11

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