SE0100902D0 - Compounds - Google Patents
CompoundsInfo
- Publication number
- SE0100902D0 SE0100902D0 SE0100902A SE0100902A SE0100902D0 SE 0100902 D0 SE0100902 D0 SE 0100902D0 SE 0100902 A SE0100902 A SE 0100902A SE 0100902 A SE0100902 A SE 0100902A SE 0100902 D0 SE0100902 D0 SE 0100902D0
- Authority
- SE
- Sweden
- Prior art keywords
- compounds
- inhibitors
- mmp12
- useful
- formula
- Prior art date
Links
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
- C07D233/78—Radicals substituted by oxygen atoms
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- A61P11/06—Antiasthmatics
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/72—Two oxygen atoms, e.g. hydantoin
- C07D233/76—Two oxygen atoms, e.g. hydantoin with substituted hydrocarbon radicals attached to the third ring carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Physical Education & Sports Medicine (AREA)
- Rheumatology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Hospice & Palliative Care (AREA)
- Endocrinology (AREA)
- Immunology (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Ophthalmology & Optometry (AREA)
- Obesity (AREA)
- Emergency Medicine (AREA)
- Otolaryngology (AREA)
- Gastroenterology & Hepatology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Reproductive Health (AREA)
Priority Applications (117)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE0100902A SE0100902D0 (sv) | 2001-03-15 | 2001-03-15 | Compounds |
UA2003098170A UA77667C2 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors, pharmaceutical composition and use thereof |
KR10-2003-7011981A KR20030082986A (ko) | 2001-03-15 | 2002-03-13 | 메탈로프로테이나제 억제제 |
RU2003127733/04A RU2285695C2 (ru) | 2001-03-15 | 2002-03-13 | Производные имидазолидин-2,4-диона, содержащие их фармацевтические композиции и их применение |
CNB02809915XA CN100526307C (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
IL15757002A IL157570A0 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
PCT/SE2002/000473 WO2002074748A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
NZ528107A NZ528107A (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
US10/471,500 US20040106659A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
PT02704031T PT1370556E (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinases |
BR0208104-0A BR0208104A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
JP2002573757A JP2004523581A (ja) | 2001-03-15 | 2002-03-13 | メタロプロテイナーゼ阻害剤 |
EEP200300439A EE200300439A (et) | 2001-03-15 | 2002-03-13 | Metalloproteinaasi inhibiitorid |
KR1020087017665A KR100879905B1 (ko) | 2001-03-15 | 2002-03-13 | 메탈로프로테이나제 억제제 |
CA002440632A CA2440632A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
MYPI20020910A MY136789A (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
CZ20032499A CZ20032499A3 (cs) | 2001-03-15 | 2002-03-13 | Inhibitory metaloproteinasy |
CNA028100417A CN1509275A (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
AU2002237626A AU2002237626B2 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
EEP200300451A EE05364B1 (et) | 2001-03-15 | 2002-03-13 | Metalloproteinaasi inhibiitorid |
IL15765202A IL157652A0 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
CZ20032502A CZ20032502A3 (cs) | 2001-03-15 | 2002-03-13 | Inhibitory metalloproteinasy |
MXPA03008181A MXPA03008181A (es) | 2001-03-15 | 2002-03-13 | Inhibidores de metaloproteinasa. |
US10/471,808 US20040147573A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
AT02704031T ATE333454T1 (de) | 2001-03-15 | 2002-03-13 | Metalloproteinaseinhibitoren |
BR0207983-6A BR0207983A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
PL364706A PL205315B1 (pl) | 2001-03-15 | 2002-03-13 | Pochodne imidazolidynodionu, środek farmaceutyczny i zastosowanie tych pochodnych |
HU0400194A HUP0400194A3 (en) | 2001-03-15 | 2002-03-13 | Imidazolidindion derivatives as metalloproteinase inhibitors, their use and pharmaceutical compositions containing them |
IL15765602A IL157656A0 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
PCT/SE2002/000478 WO2002074751A1 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
AU2002237632A AU2002237632B2 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors |
BR0207984-4A BR0207984A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
DK02704031T DK1370556T3 (da) | 2001-03-15 | 2002-03-13 | Metalloproteinaseinhibitorer |
KR1020037011987A KR100886315B1 (ko) | 2001-03-15 | 2002-03-13 | 메탈로프로테이나제 억제제 |
CN2006101061525A CN1962641B (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
MXPA03008191A MXPA03008191A (es) | 2001-03-15 | 2002-03-13 | Inhibidores de metaloproteinasa. |
DE60213216T DE60213216T2 (de) | 2001-03-15 | 2002-03-13 | Metalloproteinaseinhibitoren |
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CNB028097882A CN1304377C (zh) | 2001-03-15 | 2002-03-13 | 金属蛋白酶抑制剂 |
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ES06008158T ES2357138T3 (es) | 2001-03-15 | 2002-03-13 | Derivados de hidantoína como inhibidores de mmp. |
BR0208105-9A BR0208105A (pt) | 2001-03-15 | 2002-03-13 | Inibidores de metaloproteinase |
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JP2002573776A JP2004527515A (ja) | 2001-03-15 | 2002-03-13 | メタロプロテイナーゼ阻害剤 |
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RU2003127734/04A RU2288228C2 (ru) | 2001-03-15 | 2002-03-13 | Ингибиторы металлопротеиназ, их применение и фармацевтические композиции на их основе |
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UA2003098168A UA77408C2 (en) | 2001-03-15 | 2002-03-13 | Metalloproteinase inhibitors, pharmaceutical composition on its base, and use thereof |
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AT06008158T ATE493406T1 (de) | 2001-03-15 | 2002-03-13 | Hydantoinderivate als mmp-inhibitoren |
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