RU2633353C1 - Полученные экструзией расплава твердые дисперсии, содержащие индуцирующее апоптоз средство - Google Patents

Полученные экструзией расплава твердые дисперсии, содержащие индуцирующее апоптоз средство Download PDF

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RU2633353C1
RU2633353C1 RU2016104763A RU2016104763A RU2633353C1 RU 2633353 C1 RU2633353 C1 RU 2633353C1 RU 2016104763 A RU2016104763 A RU 2016104763A RU 2016104763 A RU2016104763 A RU 2016104763A RU 2633353 C1 RU2633353 C1 RU 2633353C1
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compound
methyl
pyridin
yloxy
chlorophenyl
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RU2016104763A
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English (en)
Russian (ru)
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Эстер РЕШ
Петер Хелиг
Дэвид Дж. ЛИНДЛИ
Йешвант Д. САНЗГИРИ
Пин ТУН
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Эббви Бахамаз Лтд.
Эбботт Гмбх Унд Ко.Кг
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    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
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    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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    • A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
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RU2016104763A 2010-10-29 2011-10-05 Полученные экструзией расплава твердые дисперсии, содержащие индуцирующее апоптоз средство RU2633353C1 (ru)

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RU2013124823/04A RU2577859C2 (ru) 2010-10-29 2011-10-05 Полученные экструзией расплава твердые дисперсии, содержащие индуцирующее апоптоз средство

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JP6141188B2 (ja) 2010-11-23 2017-06-07 アッヴィ・インコーポレイテッド アポトーシス誘導剤の塩および結晶の形態
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KR20230107902A (ko) * 2014-02-05 2023-07-18 머크 샤프 앤드 돔 엘엘씨 Cgrp-활성 화합물에 대한 정제 제제
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TW201618772A (zh) 2014-08-11 2016-06-01 艾森塔製藥公司 Ｂｔｋ抑制劑、ｐｉ３ｋ抑制劑、ｊａｋ－２抑制劑及／或ｂｃｌ－２抑制劑之治療組合物
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WO2012121758A1 (en) 2012-09-13
DK2613769T3 (en) 2018-01-08
KR20180024025A (ko) 2018-03-07
CN108175749A (zh) 2018-06-19
SI2613769T1 (en) 2018-02-28
JP2013544804A (ja) 2013-12-19
CO6781472A2 (es) 2013-10-31
EP2613769B1 (en) 2017-09-27
CY1119993T1 (el) 2018-12-12
BR112013010524A2 (pt) 2016-08-02
MX345603B (es) 2017-02-03
JP5902187B2 (ja) 2016-04-13
MX362113B (es) 2019-01-07
CN103282025A (zh) 2013-09-04
PT2613769T (pt) 2018-01-04
PH12013500686A1 (en) 2013-05-27
BR112013010524A8 (pt) 2018-02-06
ZA201401440B (en) 2015-06-24
IL226215A0 (en) 2013-07-31
JP2016147878A (ja) 2016-08-18
ZA201302669B (en) 2014-10-29
EP2613769A1 (en) 2013-07-17
SG189477A1 (en) 2013-05-31
AR122475A2 (es) 2022-09-14
EP3219308A1 (en) 2017-09-20
IL226215A (en) 2017-05-29
CA2813985A1 (en) 2012-09-13
DOP2013000092A (es) 2013-09-30
NZ608907A (en) 2015-05-29
US20150148331A1 (en) 2015-05-28
GT201300102A (es) 2014-05-20
UA113500C2 (xx) 2017-02-10
RU2013124823A (ru) 2014-12-10
NO2613769T3 (enExample) 2018-02-24
US11369599B2 (en) 2022-06-28
IL251877B (en) 2019-03-31
RU2577859C2 (ru) 2016-03-20
MX2013004843A (es) 2013-10-01
PE20140381A1 (es) 2014-04-21
KR101957137B1 (ko) 2019-03-13
ECSP22086925A (es) 2023-01-31
JP6153638B2 (ja) 2017-06-28
TWI648261B (zh) 2019-01-21

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