RU2156239C2 - Замещенные 4-(1,2,3,4-тетрагидро-1-нафталинил)-1н-имидазолы и 4-(2,3-дигидро-1н-инден-1-ил)-1н-имидазолы, способы их получения и фармацевтическая композиция на их основе - Google Patents

Замещенные 4-(1,2,3,4-тетрагидро-1-нафталинил)-1н-имидазолы и 4-(2,3-дигидро-1н-инден-1-ил)-1н-имидазолы, способы их получения и фармацевтическая композиция на их основе Download PDF

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RU2156239C2
RU2156239C2 RU95120582/04A RU95120582A RU2156239C2 RU 2156239 C2 RU2156239 C2 RU 2156239C2 RU 95120582/04 A RU95120582/04 A RU 95120582/04A RU 95120582 A RU95120582 A RU 95120582A RU 2156239 C2 RU2156239 C2 RU 2156239C2
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tetrahydro
imidazole
naphthalenyl
pharmaceutically acceptable
acceptable acids
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RU95120582/04A
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English (en)
Russian (ru)
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RU95120582A (ru
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ЖЕЕР Жан-Пьер
МОТ Женевьев
ДИФФЕРДИНГ Эдмон
ЭНИШАР Жан-Пьер
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Юцб С.А.
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C07D233/58—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU95120582/04A 1994-12-14 1995-12-13 Замещенные 4-(1,2,3,4-тетрагидро-1-нафталинил)-1н-имидазолы и 4-(2,3-дигидро-1н-инден-1-ил)-1н-имидазолы, способы их получения и фармацевтическая композиция на их основе RU2156239C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9425211.1 1994-12-14
GBGB9425211.1A GB9425211D0 (en) 1994-12-14 1994-12-14 Substituted 1H-imidazoles

Publications (2)

Publication Number Publication Date
RU95120582A RU95120582A (ru) 1997-11-10
RU2156239C2 true RU2156239C2 (ru) 2000-09-20

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RU95120582/04A RU2156239C2 (ru) 1994-12-14 1995-12-13 Замещенные 4-(1,2,3,4-тетрагидро-1-нафталинил)-1н-имидазолы и 4-(2,3-дигидро-1н-инден-1-ил)-1н-имидазолы, способы их получения и фармацевтическая композиция на их основе

Country Status (26)

Country Link
US (1) US5658938A (2)
EP (1) EP0717037A1 (2)
JP (1) JPH08208622A (2)
KR (1) KR960022474A (2)
CN (1) CN1054376C (2)
AR (1) AR002257A1 (2)
AU (1) AU693614B2 (2)
BG (1) BG63043B1 (2)
BR (1) BR9505815A (2)
CA (1) CA2165133A1 (2)
CZ (1) CZ327195A3 (2)
EE (1) EE9500064A (2)
FI (1) FI955927L (2)
GB (1) GB9425211D0 (2)
HU (1) HUT73980A (2)
IL (1) IL116325A (2)
IS (1) IS4311A (2)
MX (1) MX9505063A (2)
NO (1) NO305316B1 (2)
NZ (1) NZ280646A (2)
PL (1) PL311736A1 (2)
RO (1) RO113346B1 (2)
RU (1) RU2156239C2 (2)
SK (1) SK155095A3 (2)
TW (1) TW303362B (2)
ZA (1) ZA9510554B (2)

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AU2008285795A1 (en) * 2007-08-03 2009-02-12 F. Hoffmann-La Roche Ag Pyridinecarboxamide and benzamide derivatives as TAAR1 ligands
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US8242153B2 (en) * 2008-07-24 2012-08-14 Hoffmann-La Roche Inc. 4,5-dihydro-oxazol-2YL derivatives
RU2513086C2 (ru) * 2008-07-24 2014-04-20 Ф.Хоффманн-Ля Рош Аг Производные 4,5-дигидро-оксазол-2-ила
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RS56747B1 (sr) 2012-09-14 2018-03-30 Hoffmann La Roche Pirazol derivati karboksamida kao taar modulatori za upotrebu u lečenju nekoliko poremećaja, kao što su depresija, dijabetes i parkinsonova bolest
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HUT73980A (en) 1996-10-28
CA2165133A1 (en) 1996-06-15
FI955927A7 (fi) 1996-06-15
BR9505815A (pt) 1998-01-06
EE9500064A (et) 1996-06-17
EP0717037A1 (fr) 1996-06-19
BG63043B1 (bg) 2001-02-28
CZ327195A3 (en) 1996-07-17
NO955034D0 (no) 1995-12-12
KR960022474A (ko) 1996-07-18
AR002257A1 (es) 1998-03-11
IL116325A0 (en) 1996-03-31
IS4311A (is) 1996-06-15
CN1133837A (zh) 1996-10-23
NZ280646A (en) 1996-08-27
AU693614B2 (en) 1998-07-02
MX9505063A (es) 1997-01-31
SK155095A3 (en) 1997-02-05
FI955927A0 (fi) 1995-12-11
PL311736A1 (en) 1996-06-24
JPH08208622A (ja) 1996-08-13
NO305316B1 (no) 1999-05-10
CN1054376C (zh) 2000-07-12
BG100208A (bg) 1996-07-31
TW303362B (2) 1997-04-21
RO113346B1 (ro) 1998-06-30
IL116325A (en) 1999-10-28
HU9503549D0 (en) 1996-02-28
ZA9510554B (en) 1996-06-13
FI955927L (fi) 1996-06-15
GB9425211D0 (en) 1995-02-15
US5658938A (en) 1997-08-19
NO955034L (no) 1996-06-17
AU4036895A (en) 1996-06-20

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