RU2007101073A - Пятичленные гетероциклы, применимые в качестве ингибиторов сериновой протеазы - Google Patents

Пятичленные гетероциклы, применимые в качестве ингибиторов сериновой протеазы Download PDF

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RU2007101073A
RU2007101073A RU2007101073/04A RU2007101073A RU2007101073A RU 2007101073 A RU2007101073 A RU 2007101073A RU 2007101073/04 A RU2007101073/04 A RU 2007101073/04A RU 2007101073 A RU2007101073 A RU 2007101073A RU 2007101073 A RU2007101073 A RU 2007101073A
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Russia
Prior art keywords
substituted
phenyl
imidazol
benzyl
alkyl
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RU2007101073/04A
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English (en)
Russian (ru)
Inventor
Джон Дж. ХЭНГЕЛЭНД (US)
Джон Дж. ХЭНГЕЛЭНД
Мими Л. КВАН (US)
Мими Л. КВАН
Джоанн М. СМОЛЛХИЕР (US)
Джоанн М. СМОЛЛХИЕР
Грегори С. БИЗАЧЧИ (US)
Грегори С. БИЗАЧЧИ
Джеймс Р. КОРТ (US)
Джеймс Р. КОРТ
Тодд Дж. ФРЕНДС (US)
Тодд Дж. ФРЕНДС
Жонг СУН (US)
Жонг СУН
Карен А. РОССИ (US)
Карен А. Росси
Каллен Л. КАВАЛЛАРО (US)
Каллен Л. КАВАЛЛАРО
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Бристол-Маерс Сквибб Компани (Us)
Бристол-Маерс Сквибб Компани
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Application filed by Бристол-Маерс Сквибб Компани (Us), Бристол-Маерс Сквибб Компани filed Critical Бристол-Маерс Сквибб Компани (Us)
Publication of RU2007101073A publication Critical patent/RU2007101073A/ru

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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
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NO20065864L (no) 2007-03-02
ES2628279T3 (es) 2017-08-02
IL179844A0 (en) 2007-07-04
AU2005254102A1 (en) 2005-12-29
JP4791460B2 (ja) 2011-10-12
CA2570472A1 (en) 2005-12-29
KR20070024601A (ko) 2007-03-02
WO2005123050A3 (en) 2007-01-04
US7453002B2 (en) 2008-11-18
BRPI0512084A (pt) 2008-02-06
US9079860B2 (en) 2015-07-14
US8716492B2 (en) 2014-05-06
MXPA06014642A (es) 2007-02-12
US8101778B2 (en) 2012-01-24
US20120088758A1 (en) 2012-04-12
US20150259297A1 (en) 2015-09-17
US20140206706A1 (en) 2014-07-24
US10112936B2 (en) 2018-10-30
EP1773786A2 (en) 2007-04-18
US20050282805A1 (en) 2005-12-22
US20090036438A1 (en) 2009-02-05
US20170166560A1 (en) 2017-06-15
US9617224B2 (en) 2017-04-11
EP1773786B1 (en) 2017-04-26

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