BRPI0512084A - heterociclos de cinco membros úteis como inibidores de serina protease, composição farmacêutica contendo os mesmos, bem como seu uso - Google Patents

heterociclos de cinco membros úteis como inibidores de serina protease, composição farmacêutica contendo os mesmos, bem como seu uso

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Publication number
BRPI0512084A
BRPI0512084A BRPI0512084-5A BRPI0512084A BRPI0512084A BR PI0512084 A BRPI0512084 A BR PI0512084A BR PI0512084 A BRPI0512084 A BR PI0512084A BR PI0512084 A BRPI0512084 A BR PI0512084A
Authority
BR
Brazil
Prior art keywords
factor
formula
serine protease
compounds
pharmaceutical compositions
Prior art date
Application number
BRPI0512084-5A
Other languages
English (en)
Portuguese (pt)
Inventor
Jon J Hangeland
Mimi L Quan
Joanne M Smallheer
Gregory S Bisacchi
James R Corte
Todd J Friends
Zhong Sun
Karen A Rossi
Cullen L Cavallaro
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=35481430&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=BRPI0512084(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of BRPI0512084A publication Critical patent/BRPI0512084A/pt

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    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
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    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4164—1,3-Diazoles
    • A61K31/4178—1,3-Diazoles not condensed 1,3-diazoles and containing further heterocyclic rings, e.g. pilocarpine, nitrofurantoin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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IL179844A0 (en) 2007-07-04
AU2005254102A1 (en) 2005-12-29
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CA2570472A1 (en) 2005-12-29
KR20070024601A (ko) 2007-03-02
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US7453002B2 (en) 2008-11-18
US9079860B2 (en) 2015-07-14
US8716492B2 (en) 2014-05-06
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US8101778B2 (en) 2012-01-24
US20120088758A1 (en) 2012-04-12
US20150259297A1 (en) 2015-09-17
US20140206706A1 (en) 2014-07-24
US10112936B2 (en) 2018-10-30
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US20050282805A1 (en) 2005-12-22
US20090036438A1 (en) 2009-02-05
US20170166560A1 (en) 2017-06-15
US9617224B2 (en) 2017-04-11
EP1773786B1 (en) 2017-04-26
RU2007101073A (ru) 2008-07-20

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