RS51249B - Upotreba derivata sulfonamida sa benzo-fuzionisanim heterociklom za tretman bola - Google Patents

Upotreba derivata sulfonamida sa benzo-fuzionisanim heterociklom za tretman bola

Info

Publication number
RS51249B
RS51249B RSP-2010/0047A RSP20100047A RS51249B RS 51249 B RS51249 B RS 51249B RS P20100047 A RSP20100047 A RS P20100047A RS 51249 B RS51249 B RS 51249B
Authority
RS
Serbia
Prior art keywords
pain
treatment
benzo
group
lower alkyl
Prior art date
Application number
RSP-2010/0047A
Other languages
English (en)
Inventor
Virginia L. Smith-Swintosky
Allen B. Reitz
Original Assignee
Janssen Pharmaceutica N.V.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica N.V. filed Critical Janssen Pharmaceutica N.V.
Publication of RS51249B publication Critical patent/RS51249B/sr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D321/00—Heterocyclic compounds containing rings having two oxygen atoms as the only ring hetero atoms, not provided for by groups C07D317/00 - C07D319/00
    • C07D321/02—Seven-membered rings
    • C07D321/10—Seven-membered rings condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/357—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having two or more oxygen atoms in the same ring, e.g. crown ethers, guanadrel
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Obesity (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Emergency Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)
  • Pyrane Compounds (AREA)

Abstract

Jedinjenje formule (I)ili neka njegova farmaceutski prihvatljiva so za upotrebu u tretmanu bola, gde seR1 i R2 svaki nezavisno, se bira iz grupe koju čine vodonik i niži alkil; R4 se bira iz grupe koju čine vodonik i niži alkil;a je ceo broj od 1 do 2;se bira iz grupe koju čine:gde b predstavlja ceo broj od 0 do 4; i gde c predstavlja ceo broj od 0 do 2; R5 svaki nezavisno, se bira iz grupe koju čine halogen, niži alkil i nitro;pod uslovom da kada predstavljada je tada a jednako 1,a pri tome, termin niži alkil, se odnosi na kompoziciju ugljeničnog lanca sa 1-4 atoma ugljenika.Prijava sadrži još 10 zavisnih patentnih zahteva.
RSP-2010/0047A 2005-12-19 2006-12-19 Upotreba derivata sulfonamida sa benzo-fuzionisanim heterociklom za tretman bola RS51249B (sr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US75168605P 2005-12-19 2005-12-19
US77381206P 2006-02-15 2006-02-15
US11/612,071 US8716231B2 (en) 2005-12-19 2006-12-18 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain
PCT/US2006/048539 WO2007075752A1 (en) 2005-12-19 2006-12-19 Use of benzo-fused heterocycle sulfamide derivatives for the treatment of pain

Publications (1)

Publication Number Publication Date
RS51249B true RS51249B (sr) 2010-12-31

Family

ID=38007332

Family Applications (1)

Application Number Title Priority Date Filing Date
RSP-2010/0047A RS51249B (sr) 2005-12-19 2006-12-19 Upotreba derivata sulfonamida sa benzo-fuzionisanim heterociklom za tretman bola

Country Status (27)

Country Link
US (1) US8716231B2 (sr)
EP (1) EP1973540B1 (sr)
JP (1) JP5190377B2 (sr)
KR (1) KR20080077025A (sr)
CN (1) CN101378746B (sr)
AT (1) ATE447948T1 (sr)
AU (1) AU2006331734B2 (sr)
BR (1) BRPI0620018A2 (sr)
CA (1) CA2634115C (sr)
CR (1) CR10167A (sr)
CY (1) CY1109732T1 (sr)
DE (1) DE602006010442D1 (sr)
DK (1) DK1973540T3 (sr)
EA (1) EA016302B1 (sr)
ES (1) ES2335699T3 (sr)
HK (1) HK1125039A1 (sr)
HR (1) HRP20100007T1 (sr)
IL (1) IL192100A0 (sr)
MY (1) MY150903A (sr)
NI (1) NI200800169A (sr)
NO (1) NO20083005L (sr)
NZ (1) NZ569040A (sr)
PL (1) PL1973540T3 (sr)
PT (1) PT1973540E (sr)
RS (1) RS51249B (sr)
SI (1) SI1973540T1 (sr)
WO (1) WO2007075752A1 (sr)

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US8497298B2 (en) 2005-12-19 2013-07-30 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for lowering lipids and lowering blood glucose levels
US8937096B2 (en) 2005-12-19 2015-01-20 Janssen Pharmaceutica Nv Use of benzo-fused heterocyle sulfamide derivatives for the treatment of mania and bipolar disorder
US20070155827A1 (en) * 2005-12-19 2007-07-05 Smith-Swintosky Virginia L Use of benzo-fused heterocycle sulfamide derivatives for the treatment of depression
US8691867B2 (en) 2005-12-19 2014-04-08 Janssen Pharmaceutica Nv Use of benzo-fused heterocycle sulfamide derivatives for the treatment of substance abuse and addiction
TW200812573A (en) 2006-05-19 2008-03-16 Janssen Pharmaceutica Nv Co-therapy for the treatment of epilepsy and related disorders
US20090247616A1 (en) * 2008-03-26 2009-10-01 Smith-Swintosky Virginia L Use of benzo-fused heterocyle sulfamide derivatives for the treatment of anxiety
US20090247617A1 (en) * 2008-03-26 2009-10-01 Abdel-Magid Ahmed F Process for the preparation of benzo-fused heteroaryl sulfamates
NZ588209A (en) * 2008-04-29 2012-08-31 Nsab Af Neurosearch Sweden Ab 1-(2,3-dihydro-1,4-benzodioxin-2-yl)-methanamine derivatives for the modulation of dopaminergic function in the central nervous system
WO2009133110A1 (en) * 2008-04-29 2009-11-05 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Modulators of dopamine neurotransmission
WO2009133109A1 (en) * 2008-04-29 2009-11-05 Nsab, Filial Af Neurosearch Sweden Ab, Sverige Modulators of dopamine neurotransmission
BRPI0915890A2 (pt) 2008-06-23 2015-11-03 Janssen Pharmaceutica Nv forma cristalina de (2s)-(-)-n-(6-cloro-2,3-di-hidro-benzo[1,4]dioxin-2-ilmetil)-sulfamida
US8815939B2 (en) * 2008-07-22 2014-08-26 Janssen Pharmaceutica Nv Substituted sulfamide derivatives
AU2012316279A1 (en) 2011-09-29 2014-04-17 Janssen Pharmaceutica Nv Process for the preparation of sulfamide derivatives
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EP1973540B1 (en) 2009-11-11
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CA2634115A1 (en) 2007-07-05
US8716231B2 (en) 2014-05-06
US20070155822A1 (en) 2007-07-05
BRPI0620018A2 (pt) 2011-10-25
EA200870091A1 (ru) 2009-12-30
ATE447948T1 (de) 2009-11-15
AU2006331734A1 (en) 2007-07-05
PL1973540T3 (pl) 2010-04-30
KR20080077025A (ko) 2008-08-20
DK1973540T3 (da) 2010-02-01
DE602006010442D1 (de) 2009-12-24
NI200800169A (es) 2012-05-28
CA2634115C (en) 2014-11-18
MY150903A (en) 2014-03-14
CN101378746B (zh) 2013-07-17
WO2007075752A1 (en) 2007-07-05
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PT1973540E (pt) 2010-01-28
CR10167A (es) 2009-01-16
EP1973540A1 (en) 2008-10-01
HRP20100007T1 (hr) 2010-02-28
SI1973540T1 (sl) 2010-03-31
EA016302B1 (ru) 2012-04-30
CY1109732T1 (el) 2014-09-10
JP5190377B2 (ja) 2013-04-24
IL192100A0 (en) 2009-08-03
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NO20083005L (no) 2008-09-16
JP2009520035A (ja) 2009-05-21

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