PT3896064T - Derivados de 4,6-diamino-quinolina-3-carbonitrilo como moduladores do cancro da tiroide de osaka (cot) para o tratamento da doença de crohn e da colite ulcerosa - Google Patents

Derivados de 4,6-diamino-quinolina-3-carbonitrilo como moduladores do cancro da tiroide de osaka (cot) para o tratamento da doença de crohn e da colite ulcerosa

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Publication number
PT3896064T
PT3896064T PT211623939T PT21162393T PT3896064T PT 3896064 T PT3896064 T PT 3896064T PT 211623939 T PT211623939 T PT 211623939T PT 21162393 T PT21162393 T PT 21162393T PT 3896064 T PT3896064 T PT 3896064T
Authority
PT
Portugal
Prior art keywords
cot
diamino
quinoline
modulators
disease
Prior art date
Application number
PT211623939T
Other languages
English (en)
Portuguese (pt)
Original Assignee
Gilead Sciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gilead Sciences Inc filed Critical Gilead Sciences Inc
Publication of PT3896064T publication Critical patent/PT3896064T/pt

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    • C07—ORGANIC CHEMISTRY
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    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
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    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
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PT211623939T 2015-07-06 2016-06-30 Derivados de 4,6-diamino-quinolina-3-carbonitrilo como moduladores do cancro da tiroide de osaka (cot) para o tratamento da doença de crohn e da colite ulcerosa PT3896064T (pt)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562189158P 2015-07-06 2015-07-06
US201562269060P 2015-12-17 2015-12-17

Publications (1)

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PT3896064T true PT3896064T (pt) 2025-07-03

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Application Number Title Priority Date Filing Date
PT211623939T PT3896064T (pt) 2015-07-06 2016-06-30 Derivados de 4,6-diamino-quinolina-3-carbonitrilo como moduladores do cancro da tiroide de osaka (cot) para o tratamento da doença de crohn e da colite ulcerosa
PT181865684T PT3456717T (pt) 2015-07-06 2016-06-30 Derivado de 4,6-diamino-quinolina-3-carbonitrilo como modulador do cancro da tiróide de osaka (cot) para o tratamento de doenças inflamatórias
PT16738976T PT3191470T (pt) 2015-07-06 2016-06-30 Moduladores de cot e métodos para a sua utilização

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PT181865684T PT3456717T (pt) 2015-07-06 2016-06-30 Derivado de 4,6-diamino-quinolina-3-carbonitrilo como modulador do cancro da tiróide de osaka (cot) para o tratamento de doenças inflamatórias
PT16738976T PT3191470T (pt) 2015-07-06 2016-06-30 Moduladores de cot e métodos para a sua utilização

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AU (5) AU2016290820B2 (enExample)
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