PT2612926T - Métodos para utilização de mirna para deteção de morte celular in vivo - Google Patents

Métodos para utilização de mirna para deteção de morte celular in vivo

Info

Publication number
PT2612926T
PT2612926T PT131619850T PT13161985T PT2612926T PT 2612926 T PT2612926 T PT 2612926T PT 131619850 T PT131619850 T PT 131619850T PT 13161985 T PT13161985 T PT 13161985T PT 2612926 T PT2612926 T PT 2612926T
Authority
PT
Portugal
Prior art keywords
mirna
detection
methods
cell death
vivo cell
Prior art date
Application number
PT131619850T
Other languages
English (en)
Portuguese (pt)
Inventor
M Shekhtman Eugene
S Melkonyan Hovsep
R Umansky Samuil
S Scheinker Vladimir
Original Assignee
Trovagene Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40378881&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2612926(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Trovagene Inc filed Critical Trovagene Inc
Publication of PT2612926T publication Critical patent/PT2612926T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
    • C12Q1/701—Specific hybridization probes
    • C12Q1/705—Specific hybridization probes for herpetoviridae, e.g. herpes simplex, varicella zoster
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/118—Prognosis of disease development
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/178—Oligonucleotides characterized by their use miRNA, siRNA or ncRNA

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Immunology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Virology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
PT131619850T 2007-08-22 2008-08-22 Métodos para utilização de mirna para deteção de morte celular in vivo PT2612926T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US96587107P 2007-08-22 2007-08-22

Publications (1)

Publication Number Publication Date
PT2612926T true PT2612926T (pt) 2018-03-02

Family

ID=40378881

Family Applications (2)

Application Number Title Priority Date Filing Date
PT131619850T PT2612926T (pt) 2007-08-22 2008-08-22 Métodos para utilização de mirna para deteção de morte celular in vivo
PT87955233T PT2195450E (pt) 2007-08-22 2008-08-22 Métodos de utilização de miarn para detecção de morte celular in vivo

Family Applications After (1)

Application Number Title Priority Date Filing Date
PT87955233T PT2195450E (pt) 2007-08-22 2008-08-22 Métodos de utilização de miarn para detecção de morte celular in vivo

Country Status (16)

Country Link
US (4) US8486626B2 (enExample)
EP (2) EP2612926B1 (enExample)
JP (1) JP5416110B2 (enExample)
CN (2) CN101861399B (enExample)
AU (2) AU2008289447B2 (enExample)
CA (1) CA2696403C (enExample)
CY (1) CY1114111T1 (enExample)
DK (2) DK2612926T3 (enExample)
ES (2) ES2660785T3 (enExample)
HR (1) HRP20130618T1 (enExample)
HU (1) HUE019019T5 (enExample)
NO (1) NO2612926T3 (enExample)
PL (2) PL2612926T3 (enExample)
PT (2) PT2612926T (enExample)
TR (1) TR201802758T4 (enExample)
WO (1) WO2009025852A2 (enExample)

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CA2757711A1 (en) * 2009-04-14 2010-10-21 Merck Sharp & Dohme Corp. Microrna as a biomarker of pancreatic islet beta-cell engagement
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WO2011143659A2 (en) * 2010-05-14 2011-11-17 Fluidigm Corporation Nucleic acid isolation methods
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CN102188719B (zh) * 2011-05-12 2012-12-19 南方医科大学 EB病毒miR-BART3反义寡聚核苷酸在制备治疗鼻咽癌的药物中的应用
US9771617B2 (en) * 2011-06-27 2017-09-26 Eisai R&D Management Co., Ltd. Microrna biomarkers indicative of alzheimer's disease
WO2013022953A2 (en) * 2011-08-08 2013-02-14 Eugenia Wang Biomarker for alzheimer's disease and/or mild cognitively impairment, and use thereof
CA3067612A1 (en) * 2011-09-22 2013-03-28 Lineage Biosciences, Inc. Compositions and methods for analyzing heterogeneous samples
ITRM20110685A1 (it) 2011-12-23 2013-06-24 Internat Ct For Genetic En Gineering And Microrna per la rigenerazione cardiaca attraverso l induzione della proliferazione dei miociti cardiaci
HK1211624A1 (en) * 2012-01-27 2016-05-27 The Board Of Trustees Of The University Of The Leland Stanford Junior University Methods for profiling and quantitating cell-free rna
US20140087964A1 (en) * 2012-09-24 2014-03-27 University Of Virginia Patent Foundation Compositions and methods for detecting aberrant regulation, expression, and levels of hgh
CN104903468B (zh) * 2012-11-16 2019-04-23 萨尔大学 用于帕金森氏病的新诊断MiRNA标志物
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US11104951B2 (en) 2014-05-22 2021-08-31 The Scripps Research Institute Molecular signatures for distinguishing liver transplant rejections or injuries
US10443100B2 (en) 2014-05-22 2019-10-15 The Scripps Research Institute Gene expression profiles associated with sub-clinical kidney transplant rejection
US11062789B2 (en) 2014-07-18 2021-07-13 The Chinese University Of Hong Kong Methylation pattern analysis of tissues in a DNA mixture
EP4450636A3 (en) 2015-05-18 2025-01-01 Karius, Inc. Compositions and methods for enriching populations of nucleic acids
US10428391B2 (en) 2015-07-27 2019-10-01 The Johns Hopkins University Method to use viral and host methylation markers for cervical cancer screening and triage in liquid prep, serum/plasma, and urine: PCR and sequencing based process methods
CN108026570A (zh) * 2015-09-11 2018-05-11 康宁股份有限公司 从血液样品中纯化核酸的组合物和方法
US10975436B2 (en) 2016-01-05 2021-04-13 Diamir, Llc Methods of using miRNA from bodily fluids for diagnosis and monitoring of neurodevelopmental disorders
US11149313B2 (en) 2016-03-21 2021-10-19 Diamir, Llc Methods of using miRNAs from bodily fluids for detection and differentiation of neurodegenerative diseases
WO2018045359A1 (en) * 2016-09-02 2018-03-08 Karius, Inc. Detection and treatment of infection during pregnancy
CA3043709A1 (en) 2016-11-14 2018-05-17 Berg Llc Methods for treating parkinson's disease
WO2018099418A1 (en) 2016-11-30 2018-06-07 The Chinese University Of Hong Kong Analysis of cell-free dna in urine and other samples
US10907211B1 (en) 2017-02-16 2021-02-02 Quantgene Inc. Methods and compositions for detecting cancer biomarkers in bodily fluids
US10781487B2 (en) 2017-07-24 2020-09-22 Diamir, Llc miRNA-based methods for detecting and monitoring aging
GB2612911B (en) 2019-02-14 2023-11-22 Mirvie Inc Methods and systems for determining a pregnancy-related state of a subject
CN114449954B (zh) * 2019-10-29 2025-05-02 国立研究开发法人国立循环器病研究中心 脑梗塞治疗辅助系统
US11475981B2 (en) 2020-02-18 2022-10-18 Tempus Labs, Inc. Methods and systems for dynamic variant thresholding in a liquid biopsy assay
US11211147B2 (en) 2020-02-18 2021-12-28 Tempus Labs, Inc. Estimation of circulating tumor fraction using off-target reads of targeted-panel sequencing
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Also Published As

Publication number Publication date
ES2415245T3 (es) 2013-07-24
AU2014210676B2 (en) 2017-04-06
EP2195450A2 (en) 2010-06-16
NO2612926T3 (enExample) 2018-04-28
DK2195450T3 (da) 2013-06-24
AU2008289447A1 (en) 2009-02-26
CN105400868B (zh) 2021-03-26
CN101861399A (zh) 2010-10-13
WO2009025852A2 (en) 2009-02-26
EP2612926B1 (en) 2017-11-29
PL2195450T3 (pl) 2013-09-30
CN101861399B (zh) 2015-11-25
WO2009025852A3 (en) 2009-05-07
CN105400868A (zh) 2016-03-16
EP2612926A1 (en) 2013-07-10
US20200283851A1 (en) 2020-09-10
ES2415245T5 (es) 2016-12-23
DK2195450T4 (en) 2016-10-24
JP2010536372A (ja) 2010-12-02
DK2612926T3 (en) 2018-03-12
EP2195450B2 (en) 2016-07-20
EP2195450B1 (en) 2013-04-03
AU2014210676A1 (en) 2014-08-28
CA2696403C (en) 2018-01-02
PT2195450E (pt) 2013-07-10
AU2008289447B2 (en) 2014-09-04
ES2660785T3 (es) 2018-03-26
CY1114111T1 (el) 2016-07-27
US8486626B2 (en) 2013-07-16
JP5416110B2 (ja) 2014-02-12
TR201802758T4 (tr) 2018-03-21
HK1218767A1 (zh) 2017-03-10
US20090081640A1 (en) 2009-03-26
HUE019019T5 (en) 2017-04-28
HRP20130618T1 (en) 2013-07-31
US20180135126A1 (en) 2018-05-17
PL2612926T3 (pl) 2018-07-31
CA2696403A1 (en) 2009-02-26
US20150197805A1 (en) 2015-07-16

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